Confocal Endoscopy
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Confocal Endoscopy
Confocal endoscopy, or confocal laser endomicroscopy (CLE), is a modern Medical imaging, imaging technique that allows the Physical examination, examination of real-time Microscope, microscopic and histological features inside the body. In the word "endomicroscopy", endo- means "within" and -skopein means "to view or observe". CLE, also known as "optical biopsy", can analyse histology and cytology features of a tissue which otherwise is only possible by Biopsy, tissue biopsy. Similar to confocal microscopy, the laser in CLE filtered by the Pinhole (optics), pinhole excites the Fluorescence, fluorescent dye through a beam splitter and objective lens. The fluorescent emission then follows similar paths into the Sensor, detector. A pinhole is used to select emissions from the desired Focus (optics), focal plane. Two categories of CLE exist, namely probe-based (pCLE) and the less common endoscopy-based endoscopy (eCLE). CLE can be intubated to study the gastrointestinal tract, gastroint ...
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Medical Imaging
Medical imaging is the technique and process of imaging the interior of a body for clinical analysis and medical intervention, as well as visual representation of the function of some organs or tissues (physiology). Medical imaging seeks to reveal internal structures hidden by the skin and bones, as well as to diagnose and treat disease. Medical imaging also establishes a database of normal anatomy and physiology to make it possible to identify abnormalities. Although imaging of removed organs and tissues can be performed for medical reasons, such procedures are usually considered part of pathology instead of medical imaging. Measurement and recording techniques that are not primarily designed to produce images, such as electroencephalography (EEG), magnetoencephalography (MEG), electrocardiography (ECG), and others, represent other technologies that produce data susceptible to representation as a parameter graph versus time or maps that contain data about the measurement loca ...
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