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Clyde E. Keeler
Clyde Edgar Keeler (April 11, 1900 – April 22, 1994) was a medical geneticist who is noted for his work on laboratory mice and the genetics of vision. His work was instrumental in the understanding of retinitis pigmentosa. He also seems to have published the first scientific paper on Intrinsically photosensitive retinal ganglion cells, non-rod non-cone visual sensation. Short biographies may be found at the web site of Georgia College, which keeps the Clyde E. Keeler collection, and at the Guggenheim Foundation, where he was List of Guggenheim Fellowships awarded in 1938, made a Fellow in 1938. His daughter, Irmgard Keeler Howard, wrote a three-page obituary for ''The Journal of Heredity'' and he self-published an autobiography, ''The Gene Hunter''. The manuscript is in the Keeler Collection. References 20th-century American zoologists American geneticists People from Marion, Ohio 1900 births 1994 deaths Harvard University alumni Scientists from Ohio {{US-zoo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetics
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Irmgard (Irma) Keeler Howard
Irmgard is a feminine German given name. Notable people with the name include: * Irmgard of Berg (fl. 12th century), German noble, daughter of Adolf VI, Count of Berg * Irmgard of Chiemsee (c. 831/833 – 16 July 866) * Irmgard of Cleves (c. 1307–1362), German noble, wife of John IV, Lord of Arkel * Saint Irmgardis or Irmgard (1000–1065 or 1082/1089) * Irmgard Bartenieff (1900–1981), German dance theorist, dancer, choreographer and physical therapist * Irmgard Bensusan (born 1991), South African paralympic sprinter * Irmgard Brendenal-Böhmer, German rower * Irmgard Enderle (1895–1985), German politician, trade unionist and journalist * Irmgard Farden Aluli (1911–2001), Hawaiian composer * Irmgard Flügge-Lotz (1903–1974), German-American mathematician, aerospace engineer, and control theorist * Irmgard Fuest (1903–1980), German lawyer and politician * Irmgard Griss (born 1946), Austrian lawyer and judge, former President of the Supreme Court of Justice * Irm ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1994 Deaths
File:1994 Events Collage.png, From left, clockwise: The 1994 Winter Olympics are held in Lillehammer, Norway; The Kaiser Permanente building after the 1994 Northridge earthquake; A model of the MS Estonia, which sank in the Baltic Sea; Nelson Mandela casts his vote in the 1994 South African general election, in which he was elected South Africa's first president, and which effectively brought Apartheid to an end; NAFTA, which was signed in 1992, comes into effect in Canada, the United States, and Mexico; The first passenger rail service to utilize the newly-opened Channel tunnel; The 1994 FIFA World Cup is held in the United States; Skulls from the Rwandan genocide, in which over half a million Tutsi people were massacred by Hutus., 300x300px, thumb rect 0 0 200 200 1994 Winter Olympics rect 200 0 400 200 Northridge earthquake rect 400 0 600 200 Sinking of the MS Estonia rect 0 200 300 400 Rwandan genocide rect 300 200 600 400 Nelson Mandela rect 0 400 200 600 1994 FIFA ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1900 Births
Nineteen or 19 may refer to: * 19 (number), the natural number following 18 and preceding 20 * one of the years 19 BC, AD 19, 1919, 2019 Films * ''19'' (film), a 2001 Japanese film * ''Nineteen'' (film), a 1987 science fiction film Music * 19 (band), a Japanese pop music duo Albums * ''19'' (Adele album), 2008 * ''19'', a 2003 album by Alsou * ''19'', a 2006 album by Evan Yo * ''19'', a 2018 album by MHD * ''19'', one half of the double album ''63/19'' by Kool A.D. * ''Number Nineteen'', a 1971 album by American jazz pianist Mal Waldron * ''XIX'' (EP), a 2019 EP by 1the9 Songs * "19" (song), a 1985 song by British musician Paul Hardcastle. * "Nineteen", a song by Bad4Good from the 1992 album '' Refugee'' * "Nineteen", a song by Karma to Burn from the 2001 album ''Almost Heathen''. * "Nineteen" (song), a 2007 song by American singer Billy Ray Cyrus. * "Nineteen", a song by Tegan and Sara from the 2007 album '' The Con''. * "XIX" (song), a 2014 song by Slipk ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
People From Marion, Ohio
A person ( : people) is a being that has certain capacities or attributes such as reason, morality, consciousness or self-consciousness, and being a part of a culturally established form of social relations such as kinship, ownership of property, or legal responsibility. The defining features of personhood and, consequently, what makes a person count as a person, differ widely among cultures and contexts. In addition to the question of personhood, of what makes a being count as a person to begin with, there are further questions about personal identity and self: both about what makes any particular person that particular person instead of another, and about what makes a person at one time the same person as they were or will be at another time despite any intervening changes. The plural form "people" is often used to refer to an entire nation or ethnic group (as in "a people"), and this was the original meaning of the word; it subsequently acquired its use as a plural form of per ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Geneticists
American(s) may refer to: * American, something of, from, or related to the United States of America, commonly known as the "United States" or "America" ** Americans, citizens and nationals of the United States of America ** American ancestry, people who self-identify their ancestry as "American" ** American English, the set of varieties of the English language native to the United States ** Native Americans in the United States, indigenous peoples of the United States * American, something of, from, or related to the Americas, also known as "America" ** Indigenous peoples of the Americas * American (word), for analysis and history of the meanings in various contexts Organizations * American Airlines, U.S.-based airline headquartered in Fort Worth, Texas * American Athletic Conference, an American college athletic conference * American Recordings (record label), a record label previously known as Def American * American University, in Washington, D.C. Sports teams Soccer * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Journal Of Heredity
The ''Journal of Heredity'' is a peer-reviewed scientific journal concerned with heredity in a biological sense, covering all aspects of genetics. It is published by Oxford University Press on behalf of the American Genetic Association. History The trends in topics that have been published in the journal reflect the history of the discipline of genetics.Crow, J F (2004). "Genetics: Alive and Well. The First Hundred Years as Viewed Through the Pages of the Journal of Heredity. WILHEMINE E. KEY 2003 INVITATIONAL LECTURE". J Hered (95(5):365–374. Early issues included many papers on eugenics, particularly under the editorial leadership of the journal's first two editors-in-chief, Paul Popenoe and R. C. Cook. Emphasis on eugenics in the journal declined throughout the 1940s and 1950s as support for the topic waned in the scientific community and the general public; when Cook's daughter, Barbara Kuhn, took over as editor in 1962 after her father's 40-year service, "...the sub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Guggenheim Fellowships Awarded In 1938
Fifty-eight Guggenheim Fellowships were awarded in 1938. 1938 U.S. and Canadian Fellows 1938 Latin American and Caribbean Fellows See also * Guggenheim Fellowship * List of Guggenheim Fellowships awarded in 1937 * List of Guggenheim Fellowships awarded in 1939 References {{DEFAULTSORT:List Of Guggenheim Fellowships Awarded In 1938 1938 Events January * January 1 ** The Constitution of Estonia#Third Constitution (de facto 1938–1940, de jure 1938–1992), new constitution of Estonia enters into force, which many consider to be the ending of the Era of Silence and the a ... 1938 awards ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Intrinsically Photosensitive Retinal Ganglion Cells
Intrinsically photosensitive retinal ganglion cells (ipRGCs), also called photosensitive retinal ganglion cells (pRGC), or melanopsin-containing retinal ganglion cells (mRGCs), are a type of neuron in the retina of the mammalian eye. The presence of (something like) ipRGCs was first suspected in 1927 when rodless, coneless mice still responded to a light stimulus through pupil constriction, This implied that rods and cones are not the only light-sensitive neurons in the retina. Yet research on these cells did not advance until the 1980s. Recent research has shown that these retinal ganglion cells, unlike other retinal ganglion cells, are intrinsically photosensitive due to the presence of melanopsin, a light-sensitive protein. Therefore they constitute a third class of photoreceptors, in addition to rod and cone cells. Overview Compared to the rods and cones, the ipRGCs respond more sluggishly and signal the presence of light over the long term. They represent a very small ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Retinitis Pigmentosa
Retinitis pigmentosa (RP) is a genetic disorder of the eyes that causes loss of vision. Symptoms include trouble seeing at night and decreasing peripheral vision (side and upper or lower visual field). As peripheral vision worsens, people may experience "tunnel vision". Complete blindness is uncommon. Onset of symptoms is generally gradual and often begins in childhood. Retinitis pigmentosa is generally inherited from one or both parents or rarely it can be caused by a miscoding during DNA division. It is caused by genetic miscoding of proteins in one of more than 300 genes involved. The underlying mechanism involves the progressive loss of rod photoreceptor cells that line the retina of the eyeball. The rod cells secrete a neuroprotective substance (Rod-derived cone viability factor, RdCVF) that protects the cone cells from apoptosis (cell death). However, when the rod cells die, this substance is no longer provided. This is generally followed by the loss of cone photorecept ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Laboratory Mice
The laboratory mouse or lab mouse is a small mammal of the order Rodentia which is bred and used for scientific research or feeders for certain pets. Laboratory mice are usually of the species ''Mus musculus''. They are the most commonly used mammalian research model and are used for research in genetics, physiology, psychology, medicine and other scientific disciplines. Mice belong to the Euarchontoglires clade, which includes humans. This close relationship, the associated high homology with humans, their ease of maintenance and handling, and their high reproduction rate, make mice particularly suitable models for human-oriented research. The laboratory mouse genome has been sequenced and many mouse genes have human homologues. Other mouse species sometimes used in laboratory research include two American species, the white-footed mouse (''Peromyscus leucopus'') and the North American deer mouse (''Peromyscus maniculatus''). History as a biological model Mice have been ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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