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Club Cell
Club cells, also known as bronchiolar exocrine cells, and formerly known as Clara cells, are low columnar/cuboidal cells with short microvilli, found in the small airways ( bronchioles) of the lungs. Club cells are found in the ciliated simple epithelium. These cells may secrete glycosaminoglycans to protect the bronchiole lining. Bronchiolar cells gradually increase in number as the number of goblet cells decrease. One of the main functions of club cells is to protect the bronchiolar epithelium. They do this by secreting a small variety of products, including club cell secretory protein uteroglobin, and a solution similar in composition to pulmonary surfactant. They are also responsible for detoxifying harmful substances inhaled into the lungs. Club cells accomplish this with cytochrome P450 enzymes found in their smooth endoplasmic reticulum. Club cells also act as a stem cell, multiplying and differentiating into ciliated cells to regenerate the bronchiolar epithelium. Funct ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cell (biology)
The cell is the basic structural and functional unit of life forms. Every cell consists of a cytoplasm enclosed within a membrane, and contains many biomolecules such as proteins, DNA and RNA, as well as many small molecules of nutrients and metabolites.Cell Movements and the Shaping of the Vertebrate Body in Chapter 21 of Molecular Biology of the Cell '' fourth edition, edited by Bruce Alberts (2002) published by Garland Science. The Alberts text discusses how the "cellular building blocks" move to shape developing embryos. It is also common to describe small molecules such as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Influenza A
'' A virus'' (''IAV'') causes influenza in birds and some mammals, and is the only species of the genus ''Alphainfluenzavirus'' of the virus family '' Orthomyxoviridae''. Strains of all subtypes of influenza A virus have been isolated from wild birds, although disease is uncommon. Some isolates of influenza A virus cause severe disease both in domestic poultry and, rarely, in humans. Occasionally, viruses are transmitted from wild aquatic birds to domestic poultry, and this may cause an outbreak or give rise to human influenza pandemics. Influenza A viruses are negative-sense, single-stranded, segmented RNA viruses. The several subtypes are labeled according to an H number (for the type of hemagglutinin) and an N number (for the type of neuraminidase). There are 18 different known H antigens (H1 to H18) and 11 different known N antigens (N1 to N11). H17N10 was isolated from fruit bats in 2012. H18N11 was discovered in a Peruvian bat in 2013. Each virus subtype has mutated i ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Skatole
Skatole or 3-methylindole is an organic compound belonging to the indole family. It occurs naturally in the feces of mammals and birds and is the primary contributor to fecal odor. In low concentrations, it has a flowery smell and is found in several flowers and essential oils, including those of orange blossoms, jasmine, and ''Ziziphus mauritiana''. It is used as a fragrance and fixative in many perfumes and as an aroma compound. Its name derives from the Greek root ''skato-'', meaning feces. Skatole was discovered in 1877 by the German physician Ludwig Brieger (1849–1919). Original: "''Ich habe mich zuerst mit der Untersuchung der flüchtigen Bestandtheile der Excremente aus sauerer Lösung beschäftigt. Es wurden dabei die flüchtigen Fettsäuren: Essigsäure, normale und Isobuttersäure, sowie die aromatischen Substanzen: Phenol, Indol und eine neue dem Indol verwandte Substanz, die ich Skatol nennen werde, erhalten."'' ----''Translation'': "I was occupied initial ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Medical Eponyms With Nazi Associations
This article lists medical eponyms which have been associated with Nazi human experimentation or Nazi politics. While normally eponyms used in medicine serve to honor the memory of the physician or researcher who first documented a disease or pioneered a procedure, the propriety of such names resulting from unethical research practices is controversial. In some cases terms closely related to doctors in the Nazi era have fallen out of favor or there are active lobbying efforts to remove the original name from use. In other cases their use in the medical literature is sometimes presented with a caveat or footnote. The declining use of the Nazi-era eponyms has itself been tracked in the literature. Since 2007, the ''Israel Medical Association Journal'' and ''European Neurology'' have each published articles cataloging eponyms honoring Nazis and their collaborators. While the most direct Nazi experimenters (such as Josef Mengele) were never honored, others who were members of the Naz ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
CGMP-dependent Protein Kinase
cGMP-dependent protein kinase or protein kinase G (PKG) is a serine/threonine-specific protein kinase that is activated by cGMP. It phosphorylates a number of biologically important targets and is implicated in the regulation of smooth muscle relaxation, platelet function, sperm metabolism, cell division, and nucleic acid synthesis. Genes and proteins PKG are serine/threonine kinases that are present in a variety of eukaryotes ranging from the unicellular organism ''Paramecium'' to humans. Two PKG genes, coding for PKG type I (PKG-I) and type II (PKG-II), have been identified in mammals. The N-terminus of PKG-I is encoded by two alternatively spliced exons that specify for the PKG-Iα and PKG-Iβ isoforms. PKG-Iβ is activated at ~10-fold higher cGMP concentrations than PKG-Iα. The PKG-I and PKG-II are homodimers of two identical subunits (~75 kDa and ~85 kDa, respectively) and share common structural features. Each subunit is composed of three functional domains: * ( ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eponym
An eponym is a person, a place, or a thing after whom or which someone or something is, or is believed to be, named. The adjectives which are derived from the word eponym include ''eponymous'' and ''eponymic''. Usage of the word The term ''eponym'' functions in multiple related ways, all based on an explicit relationship between two named things. A person, place, or thing named after a particular person share an eponymous relationship. In this way, Elizabeth I of England is the eponym of the Elizabethan era. When Henry Ford is referred to as "the ''eponymous'' founder of the Ford Motor Company", his surname "Ford" serves as the eponym. The term also refers to the title character of a fictional work (such as Rocky Balboa of the Rocky film series, ''Rocky'' film series), as well as to ''self-titled'' works named after their creators (such as the album The Doors (album), ''The Doors'' by the band the Doors). Walt Disney created the eponymous The Walt Disney Company, Walt Disney Com ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American College Of Chest Physicians
The American College of Chest Physicians (CHEST) is a medical association in the United States consisting of physicians and non-physician specialists in the field of chest medicine, which includes pulmonology, critical care medicine, and sleep medicine Sleep medicine is a medical specialty or subspecialty devoted to the diagnosis and therapy of sleep disturbances and sleep disorder, disorders. From the middle of the 20th century, research has provided increasing knowledge and answered many .... The group was founded in 1935. It has a membership of over 19,000. See also * ''Chest'' (journal) References External linksOfficial website* {{authority control Medical associations based in the United States Professional titles and certifications Pulmonology and respiratory therapy organizations Scientific organizations established in 1935 Medical and health professional associations in Chicago ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
European Respiratory Society
The European Respiratory Society, or ERS, is a non-profit organization with offices in Lausanne, Brussels and Sheffield. It was founded in 1990 in the field of respiratory medicine. The organization was formed with the merger of the Societas Europaea Physiologiae Clinicae Respoiratoriae (founded in 1966) and the European Society of Pneumology (founded 1981). The organization's membership is made up of medical professionals and scientists working in the area of respiratory medicine. ERS founded thEuropean Lung Foundation(ELF) in 2000. The foundation aims to bring together patients and the public with respiratory professionals to positively influence lung health. Activities The ERS publishes academic journals and books as well as hosting events aimed at educating health professionals, including a large annual congress. The organization's stated goal is to "promote lung health in order to alleviate suffering from disease and drive standards for respiratory medicine globally". Publi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
American Thoracic Society
The American Thoracic Society (ATS) is a nonprofit organization focused on improving care for pulmonary diseases, critical illnesses and sleep-related breathing disorders. It was established in 1905 as the American Sanatorium Association, and changed its name in 1938 to the American Trudeau Society. In 1960, it changed its name again to the American Thoracic Society. Originally the medical section of the American Lung Association, the Society became independently incorporated in 2000 as a 501 (c) (3) organization. Medical and scientific areas of interest Pulmonology, critical care, sleep medicine, infectious disease, pediatrics, allergy/immunology, thoracic surgery, behavioral science, environmental and occupational medicine, physiology, molecular biology, among others. Membership More than 15,000 physicians, research scientists, and nurses and other allied healthcare professionals (32 percent of whom work outside the United States). ATS Assemblies The interests of members ar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nazi Germany
Nazi Germany (lit. "National Socialist State"), ' (lit. "Nazi State") for short; also ' (lit. "National Socialist Germany") (officially known as the German Reich from 1933 until 1943, and the Greater German Reich from 1943 to 1945) was the German state between 1933 and 1945, when Adolf Hitler and the Nazi Party controlled the country, transforming it into a dictatorship. Under Hitler's rule, Germany quickly became a totalitarian state where nearly all aspects of life were controlled by the government. The Third Reich, meaning "Third Realm" or "Third Empire", alluded to the Nazi claim that Nazi Germany was the successor to the earlier Holy Roman Empire (800–1806) and German Empire (1871–1918). The Third Reich, which Hitler and the Nazis referred to as the Thousand-Year Reich, ended in May 1945 after just 12 years when the Allies defeated Germany, ending World War II in Europe. On 30 January 1933, Hitler was appointed chancellor of Germany, the head of gove ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nazi Party
The Nazi Party, officially the National Socialist German Workers' Party (german: Nationalsozialistische Deutsche Arbeiterpartei or NSDAP), was a far-right politics, far-right political party in Germany active between 1920 and 1945 that created and supported the ideology of Nazism. Its precursor, the German Workers' Party (; DAP), existed from 1919 to 1920. The Nazi Party emerged from the Extremism, extremist German nationalism, German nationalist, racism, racist and populism, populist paramilitary culture, which fought against the communism, communist uprisings in post–World War I Germany. The party was created to draw workers away from communism and into nationalism. Initially, Nazi political strategy focused on anti–big business, anti-bourgeoisie, bourgeois, and anti-capitalism, anti-capitalist rhetoric. This was later downplayed to gain the support of business leaders, and in the 1930s, the party's main focus shifted to Antisemitism, antisemitic and Criticism of ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Max Clara
Max Clara (12 February 1899, Völs am Schlern, Austro-Hungary – 13 March 1966, Munich) was a German anatomy, anatomist and Nazi Party member, who conducted research on the corpses of executed prisoners. Biography Early life Max Clara was born on February 12th, 1899 in South Tyrol, at that time part of the Habsburg monarchy, Habsburg Empire. His father, Dr. Josef Clara, graduated with honors at the University of Innsbruck and started working as a general practitioner. Max(imilian) Josef Maria Clara was born as the first of three sons: his younger brothers Josef "Sepp" Franz and Oswald were born on August 18th, 1900, and July 12th, 1902, respectively. After their mother's death (5 August 1903), Josef Clara moved his residence and the seat of his surgery to the village of Blumau-Neurißhof, Blumau, where he built a sanatorium at the Brenner, South Tyrol, Brenner road near the train station. Max Clara graduated from the Franziskaner-Gymnasium in the nearby city of Bolzano, ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
