Clostebol
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Clostebol
Clostebol (; also known as 4-chlorotestosterone) usually as the ester clostebol acetate, is a synthetic anabolic–androgenic steroid (AAS). Clostebol is the 4- chloro derivative of the natural hormone testosterone. The chlorination prevents conversion to dihydrotestosterone (DHT) while also rendering the chemical incapable of conversion to estrogen. Although usually used as an ester including clostebol acetate (Macrobin, Steranabol, Alfa-Trofodermin, Megagrisevit), clostebol caproate (Macrobin-Depot), or clostebol propionate (Yonchlon), unmodified/non-esterified clostebol is also reported to be marketed, under the brand name Trofodermin-S in Mexico. Clostebol is a weak AAS with potential use as a performance enhancing drug. It is currently banned by the World Anti-Doping Agency. Chlorodehydromethyltestosterone (Oral Turinabol), combining the chemical structures of clostebol and metandienone, was widely used in the East German state-sponsored doping program. Medical uses ...
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Clostebol Caproate
Clostebol caproate (brand name Macrobin-Depot), also known as clostebol hexanoate or chlorotestosterone caproate (JAN), as well as 4-chlorotestosterone 17β-caproate or as 4-chloroandrost-4-en-17β-ol-3-one 17β-caproate, is a synthetic, injected anabolic-androgenic steroid (AAS) and a derivative of testosterone. It is an androgen ester – specifically, the C17β caproate ester of clostebol (4-chlorotestosterone) – and acts as a prodrug of clostebol in the body. Clostebol acetate is administered via intramuscular injection. See also * Clostebol acetate * Clostebol propionate * Norclostebol * Norclostebol acetate * Oxabolone * Oxabolone cipionate Oxabolone cipionate (, ) (brand names Steranabol Depo, Steranabol Ritardo; former developmental code name FI-5852), or oxabolone cypionate, also known as 4-hydroxy-19-nortestosterone 17β-cypionate or estr-4-en-4,17β-diol-3-one 17β-cypionate, is ... References Androgen esters Androgens and anabolic steroids Androsta ...
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Viktoria Orsi Toth
Viktoria Orsi Toth (born 14 August 1990) is an Italian beach volleyball player who plays as a right-side blocker. With partner Marta Menegatti, she achieved a career-high world ranking of No. 7 in June 2016. Her career highlights include two gold, three silver and two bronze medals on the FIVB World Tour. Born in Hungary, her family moved to Italy when Orsi Toth was five. She began her sporting career playing indoor volleyball for various clubs, including two seasons in the Serie A1. As a member of the Italy women's national under-20 team, she won the 2008 Junior European Volleyball Championship. Orsi Toth competed in her first international beach volleyball event in 2010 and quit indoor volleyball the following year to focus solely on the beach game. Orsi Toth debuted on the World Tour in 2011. For the next two and a half seasons, she was mostly partnered with Laura Giombini and struggled to qualify for main draws. Her breakthrough came mid-2013 when she teamed up with ...
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Clostebol Propionate
Clostebol propionate (brand name Yonchlon), also known as 4-chlorotestosterone 17β-propionate or as 4-chloroandrost-4-en-17β-ol-3-one 17β-propionate, is a synthetic, injected anabolic-androgenic steroid (AAS) and a derivative of testosterone. It is an androgen ester – specifically, the C17β propionate ester of clostebol (4-chlorotestosterone) – and acts as a prodrug of clostebol in the body. Clostebol acetate is administered via intramuscular injection. See also * Clostebol acetate * Clostebol caproate * Norclostebol * Norclostebol acetate * Oxabolone * Oxabolone cipionate Oxabolone cipionate (, ) (brand names Steranabol Depo, Steranabol Ritardo; former developmental code name FI-5852), or oxabolone cypionate, also known as 4-hydroxy-19-nortestosterone 17β-cypionate or estr-4-en-4,17β-diol-3-one 17β-cypionate, is ... References Propionate esters Androgen esters Androgens and anabolic steroids Androstanes Organochlorides Prodrugs World Anti-Doping ...
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Clostebol Acetate
Clostebol acetate ( BAN) (brand names Macrobin, Steranabol, Alfa-Trofodermin, Megagrisevit), also known as 4-chlorotestosterone 17β-acetate (4-CLTA) or as 4-chloroandrost-4-en-17β-ol-3-one 17β-acetate, is a synthetic, injected anabolic-androgenic steroid (AAS) and a derivative of testosterone that is marketed in Germany and Italy. It is an androgen ester – specifically, the C17β acetate ester of clostebol (4-chlorotestosterone) – and acts as a prodrug of clostebol in the body. Clostebol acetate is administered via intramuscular injection. See also * Clostebol caproate * Clostebol propionate * Norclostebol * Norclostebol acetate * Oxabolone * Oxabolone cipionate Oxabolone cipionate (, ) (brand names Steranabol Depo, Steranabol Ritardo; former developmental code name FI-5852), or oxabolone cypionate, also known as 4-hydroxy-19-nortestosterone 17β-cypionate or estr-4-en-4,17β-diol-3-one 17β-cypionate, is ... References Acetate esters Androgen esters Andro ...
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Methylclostebol
Methylclostebol, also known as 4-chloro-17α-methyltestosterone or as 4-chloro-17α-methylandrost-4-en-17β-ol-3-one, is a synthetic, orally active anabolic-androgenic steroid (AAS) and designer steroid that has been sold on the Internet as a " dietary supplement", but it has never been studied for medical use. It is the 17α-alkylated variant of clostebol (4-chlorotestosterone).Lootens, L., Van Eenoo, P., Pozo Mendoza, O. J., Meulemans, P., Leroux-Roels, G., & Delbeke, F. (2010). Application of in vivo urinary steroid detection in uPA+/+-SCID chimeric mice. In 28th Cologne workshop on Dope Analysis (Manfred Donike workshop) (Vol. 18, pp. 52-61). Sportverlag Strauss. Rahnema, Crosnoe, and Kim (2015) reported that German athletes used methylclostebol as a performance enhancing drug in the 1960s and 1970s, but this has not been substantiated. The compound is listed as a banned anabolic agent by the World Anti-Doping Agency. See also * Chlorodehydromethylandrostenediol * Chlor ...
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Chlorodehydromethyltestosterone
Chlorodehydromethyltestosterone (CDMT; brand name Oral Turinabol), also known as 4-chloro-17β-hydroxy17α-methylandrosta-1,4-dien-3-one, is an anabolic–androgenic steroid (AAS). It is the 4-chloro-substituted derivative of metandienone (dehydromethyltestosterone). Side effects *Chlorodehydromethyltestosterone History CDMT was the first original product of Jenapharm, an East German pharmaceutical company. It was patented in 1961. The idea of combining the structures of 4-chlorotestosterone (clostebol) and metandienone originated with chemist Albert Stachowiak. At the time, this represented a unique dissociation of anabolic from androgenic effects after oral administration. The product was introduced for clinical use in 1965 and remained in use until 1994, when production was discontinued. Society and culture Doping in sports CDMT was the key steroid administered to approximately ten thousand East German athletes as part of a secret doping program, known as State Pla ...
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Dee Gordon
Devaris "Dee" Strange-Gordon (born April 22, 1988) is an American professional baseball second baseman, shortstop, and center fielder who is currently a free agent. He has played Major League Baseball (MLB) for the Los Angeles Dodgers, Miami Marlins, Seattle Mariners and Washington Nationals. Strange-Gordon was primarily a shortstop and second baseman, and with the Marlins, he was primarily a second baseman. He began his tenure with the Mariners by playing center field in 2018, and started playing left field in 2020. In 2015, in his first season with the Marlins, Strange-Gordon hit .333 with a total of 205 hits and stole 58 bases. He led the NL in all three categories and became the first player to lead the National League in both batting average and stolen bases since fellow second baseman Jackie Robinson in 1949. Through the 2010s, Strange-Gordon stole 330 bases, the most of any player. On April 29, 2016, Major League Baseball suspended Strange-Gordon for 80 games due to perf ...
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Anabolic Steroid
Anabolic steroids, also known more properly as anabolic–androgenic steroids (AAS), are steroidal androgens that include natural androgens like testosterone as well as synthetic androgens that are structurally related and have similar effects to testosterone. They increase protein within cells, especially in skeletal muscles, and also have varying degrees of virilizing effects, including induction of the development and maintenance of masculine secondary sexual characteristics such as the growth of facial hair, facial and body hair. The word ''anabolic'', referring to anabolism, comes from the Greek ἀναβολή ''anabole'', "that which is thrown up, mound". Androgens or AAS are one of three types of sex hormone agonists, the others being estrogen (medication), estrogens like estradiol (medication), estradiol and progestogens like progesterone (medication), progesterone. AAS were synthesized in the 1930s, and are now used therapeutically in medicine to stimulate muscle g ...
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Anabolic–androgenic Steroid
Anabolic steroids, also known more properly as anabolic–androgenic steroids (AAS), are steroidal androgens that include natural androgens like testosterone as well as synthetic androgens that are structurally related and have similar effects to testosterone. They increase protein within cells, especially in skeletal muscles, and also have varying degrees of virilizing effects, including induction of the development and maintenance of masculine secondary sexual characteristics such as the growth of facial and body hair. The word ''anabolic'', referring to anabolism, comes from the Greek ἀναβολή ''anabole'', "that which is thrown up, mound". Androgens or AAS are one of three types of sex hormone agonists, the others being estrogens like estradiol and progestogens like progesterone. AAS were synthesized in the 1930s, and are now used therapeutically in medicine to stimulate muscle growth and appetite, induce male puberty and treat chronic wasting conditions, such as cance ...
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Androgen
An androgen (from Greek ''andr-'', the stem of the word meaning "man") is any natural or synthetic steroid hormone that regulates the development and maintenance of male characteristics in vertebrates by binding to androgen receptors. This includes the embryological development of the primary male sex organs, and the development of male secondary sex characteristics at puberty. Androgens are synthesized in the testes, the ovaries, and the adrenal glands. Androgens increase in both males and females during puberty. The major androgen in males is testosterone. Dihydrotestosterone (DHT) and androstenedione are of equal importance in male development. DHT ''in utero'' causes differentiation of the penis, scrotum and prostate. In adulthood, DHT contributes to balding, prostate growth, and sebaceous gland activity. Although androgens are commonly thought of only as male sex hormones, females also have them, but at lower levels: they function in libido and sexual arousal. Al ...
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Chlorine
Chlorine is a chemical element with the symbol Cl and atomic number 17. The second-lightest of the halogens, it appears between fluorine and bromine in the periodic table and its properties are mostly intermediate between them. Chlorine is a yellow-green gas at room temperature. It is an extremely reactive element and a strong oxidising agent: among the elements, it has the highest electron affinity and the third-highest electronegativity on the revised Pauling scale, behind only oxygen and fluorine. Chlorine played an important role in the experiments conducted by medieval alchemists, which commonly involved the heating of chloride salts like ammonium chloride ( sal ammoniac) and sodium chloride (common salt), producing various chemical substances containing chlorine such as hydrogen chloride, mercury(II) chloride (corrosive sublimate), and hydrochloric acid (in the form of ). However, the nature of free chlorine gas as a separate substance was only recognised aroun ...
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Philadelphia Phillies
The Philadelphia Phillies are an American professional baseball team based in Philadelphia. They compete in Major League Baseball (MLB) as a member of the National League (NL) National League East, East division. Since 2004, the team's home stadium has been Citizens Bank Park, located in the South Philadelphia Sports Complex. Founded in 1883, the Philadelphia Phillies are the oldest continuous same-name, same-city franchise in all of American professional sports. The Phillies have won two World Series championships (against the Kansas City Royals in and the Tampa Bay Rays in ), eight National League pennants (the first of which came in 1915), and made 15 playoff appearances. As of November 6, 2022, the team has played 21,209 games, winning 10,022 games and losing 11,187. Since the first modern World Series was played in , the Phillies have played 120 consecutive seasons and 140 seasons since the team's 1883 establishment. Before the Phillies won their first World Series in 19 ...
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