Ciguatera Poisoning
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Ciguatera Poisoning
Ciguatera fish poisoning (CFP), also known simply as ciguatera, is a foodborne illness caused by eating reef fish whose flesh is contaminated with certain toxins. Such individual fish are said to be ciguatoxic. Symptoms may include diarrhea, vomiting, numbness, itchiness, sensitivity to hot and cold, dizziness, and weakness. The onset of symptoms varies with the amount of toxin eaten from half an hour to up to two days. The diarrhea may last for up to four days. Some symptoms typically remain for a few weeks to months. Heart difficulties such as slow heart rate and low blood pressure may also occur. The specific toxins involved are ciguatoxin and maitotoxin. They are originally made by a small marine organism, ''Gambierdiscus toxicus'', that grows on and around coral reefs in tropical and subtropical waters. These are eaten by herbivorous fish which in turn are eaten by larger carnivorous fish. The toxins become more concentrated as they move up the food chain. The fish mo ...
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Ciguatoxin
300px, Chemical structure of the ciguatoxin CTX1B Ciguatoxins are a class of toxic polycyclic polyethers found in fish that cause ciguatera. There are several different chemicals in this class. "CTX" is often used as an abbreviation. * - Ciguatoxin 1 * - Ciguatoxin 2 * - Ciguatoxin 3 * - Ciguatoxin 4B (Gambiertoxin 4b) Toxic effect on humans Ciguatoxins do not harm the fish that carry them, but they are poisonous to humans. They cannot be smelled or tasted and cannot be destroyed by cooking. Rapid testing for this toxin in food is not standard. Some ciguatoxins lower the threshold for opening excitatory voltage-gated sodium channels in the nervous system. Opening a sodium channel causes depolarization, which could sequentially cause paralysis, heart contraction, and changing the senses of heat and cold. Such poisoning from ciguatoxins is known as ciguatera. Ciguatoxins are lipophillic, able to cross the blood brain barrier, and can cause both central and peripheral ...
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Gabapentin
Gabapentin, sold under the brand name Neurontin among others, is an anticonvulsant medication primarily used to treat partial seizures and neuropathic pain. It is a first-line medication for the treatment of neuropathic pain caused by diabetic neuropathy, postherpetic neuralgia, and central pain. It is moderately effective: about 30–40% of those given gabapentin for diabetic neuropathy or postherpetic neuralgia have a meaningful benefit. Sleepiness and dizziness are the most common side effects. Serious side effects include an increased risk of suicide, respiratory depression, and allergic reactions. Lower doses are recommended in those with kidney disease. Gabapentin acts by decreasing activity of a subset of calcium channels. Gabapentin was first approved for use in 1993. It has been available as a generic medication in the United States since 2004. In 2020, it was the tenth most commonly prescribed medication in the United States, with more than 49million prescriptio ...
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Carnivorous
A carnivore , or meat-eater (Latin, ''caro'', genitive ''carnis'', meaning meat or "flesh" and ''vorare'' meaning "to devour"), is an animal or plant whose food and energy requirements derive from animal tissues (mainly muscle, fat and other soft tissues) whether through hunting or scavenging. Nomenclature Mammal order The technical term for mammals in the order Carnivora is ''carnivoran'', and they are so-named because most member species in the group have a carnivorous diet, but the similarity of the name of the order and the name of the diet causes confusion. Many but not all carnivorans are meat eaters; a few, such as the large and small cats ( felidae) are ''obligate'' carnivores (see below). Other classes of carnivore are highly variable. The Ursids, for example: While the Arctic polar bear eats meat almost exclusively (more than 90% of its diet is meat), almost all other bear species are omnivorous, and one species, the giant panda, is nearly exclusively herbivo ...
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Herbivorous
A herbivore is an animal anatomically and physiologically adapted to eating plant material, for example foliage or marine algae, for the main component of its diet. As a result of their plant diet, herbivorous animals typically have mouthparts adapted to rasping or grinding. Horses and other herbivores have wide flat teeth that are adapted to grinding grass, tree bark, and other tough plant material. A large percentage of herbivores have mutualistic gut flora that help them digest plant matter, which is more difficult to digest than animal prey. This flora is made up of cellulose-digesting protozoans or bacteria. Etymology Herbivore is the anglicized form of a modern Latin coinage, ''herbivora'', cited in Charles Lyell's 1830 '' Principles of Geology''.J.A. Simpson and E.S.C. Weiner, eds. (2000) ''The Oxford English Dictionary'', vol. 8, p. 155. Richard Owen employed the anglicized term in an 1854 work on fossil teeth and skeletons. ''Herbivora'' is derived from Latin ''herb ...
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Subtropical
The subtropical zones or subtropics are geographical and climate zones to the north and south of the tropics. Geographically part of the temperate zones of both hemispheres, they cover the middle latitudes from to approximately 35° north and south. The horse latitudes lie within this range. Subtropical climates are often characterized by hot summers and mild winters with infrequent frost. Most subtropical climates fall into two basic types: humid subtropical ( Koppen climate Cfa), where rainfall is often concentrated in the warmest months, for example Southeast China and the Southeastern United States, and dry summer or Mediterranean climate ( Koppen climate Csa/Csb), where seasonal rainfall is concentrated in the cooler months, such as the Mediterranean Basin or Southern California. Subtropical climates can also occur at high elevations within the tropics, such as in the southern end of the Mexican Plateau and in Da Lat of the Vietnamese Central Highlands. The six c ...
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Tropical
The tropics are the regions of Earth surrounding the Equator. They are defined in latitude by the Tropic of Cancer in the Northern Hemisphere at N and the Tropic of Capricorn in the Southern Hemisphere at S. The tropics are also referred to as the tropical zone and the torrid zone (see geographical zone). In terms of climate, the tropics receive sunlight that is more direct than the rest of Earth and are generally hotter and wetter as they aren't affected as much by the solar seasons. The word "tropical" sometimes refers to this sort of climate in the zone rather than to the geographical zone itself. The tropical zone includes deserts and snow-capped mountains, which are not tropical in the climatic sense. The tropics are distinguished from the other climatic and biomatic regions of Earth, which are the middle latitudes and the polar regions on either side of the equatorial zone. The tropics constitute 40% of Earth's surface area and contain 36% of Earth's landmass. , t ...
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Coral Reefs
A coral reef is an underwater ecosystem characterized by reef-building corals. Reefs are formed of colonies of coral polyps held together by calcium carbonate. Most coral reefs are built from stony corals, whose polyps cluster in groups. Coral belongs to the class Anthozoa in the animal phylum Cnidaria, which includes sea anemones and jellyfish. Unlike sea anemones, corals secrete hard carbonate exoskeletons that support and protect the coral. Most reefs grow best in warm, shallow, clear, sunny and agitated water. Coral reefs first appeared 485 million years ago, at the dawn of the Early Ordovician, displacing the microbial and sponge reefs of the Cambrian. Sometimes called ''rainforests of the sea'', shallow coral reefs form some of Earth's most diverse ecosystems. They occupy less than 0.1% of the world's ocean area, about half the area of France, yet they provide a home for at least 25% of all marine species, including fish, mollusks, worms, crustaceans, echinoderms, ...
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Gambierdiscus Toxicus
''Gambierdiscus toxicus'' is a species of photosynthetic unicellular eukaryote belonging to the Alveolata, part of the SAR supergroup. It is a dinoflagellate which can cause the foodborne illness ciguatera, and is known to produce several natural polyethers including ciguatoxin, maitotoxin, gambieric acid, and gambierol. The species was discovered attached to the surface of brown macroalgae. History This species was first described by Adachi, R. & Fukuyo, Y in 1979 using samples collected around Gambier Islands. Which was split into five different species (''Gambierdiscus caribaeus'', ''Gambierdiscus carolinianus'', ''Gambierdiscus carpenteri'', ''Gambierdiscus ruetzleri'' and ''Gambierdiscus toxicus'') according to their morphological characteristic of thecal structure, and the sequence of both D1–D3 and D8–D10 regions in large-subunit rDNA. Distribution This species can be found in tropical and subtropical regions in Pacific Ocean and Indian Ocean. It is often f ...
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Marine Organism
Marine life, sea life, or ocean life is the plants, animals and other organisms that live in the salt water of seas or oceans, or the brackish water of coastal estuaries. At a fundamental level, marine life affects the nature of the planet. Marine organisms, mostly microorganisms, produce oxygen and sequester carbon. Marine life in part shape and protect shorelines, and some marine organisms even help create new land (e.g. coral building reefs). Most life forms evolved initially in marine habitats. By volume, oceans provide about 90% of the living space on the planet. The earliest vertebrates appeared in the form of fish, which live exclusively in water. Some of these evolved into amphibians, which spend portions of their lives in water and portions on land. One group of amphibians evolved into reptiles and mammals and a few subsets of each returned to the ocean as sea snakes, sea turtles, seals, manatees, and whales. Plant forms such as kelp and other algae grow in the wate ...
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Low Blood Pressure
Hypotension is low blood pressure. Blood pressure is the force of blood pushing against the walls of the arteries as the heart pumps out blood. Blood pressure is indicated by two numbers, the systolic blood pressure (the top number) and the diastolic blood pressure (the bottom number), which are the maximum and minimum blood pressures, respectively. A systolic blood pressure of less than 90 millimeters of mercury (mmHg) or diastolic of less than 60 mmHg is generally considered to be hypotension. Different numbers apply to children. However, in practice, blood pressure is considered too low only if noticeable symptoms are present. Symptoms include dizziness or lightheadedness, confusion, feeling tired, weakness, headache, blurred vision, nausea, neck or back pain, an irregular heartbeat or feeling that the heart is skipping beats or fluttering, or fainting. Hypotension is the opposite of hypertension, which is high blood pressure. It is best understood as a physiolog ...
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Bradycardia
Bradycardia (also sinus bradycardia) is a slow resting heart rate, commonly under 60 beats per minute (BPM) as determined by an electrocardiogram. It is considered to be a normal heart rate during sleep, in young and healthy or elderly adults, and in athletes. In some people, bradycardia below 60 BPM may be associated with fatigue, weakness, dizziness, sweating, and fainting. The term "relative bradycardia" is used to refer to a heart rate slower than an individual's typical resting heart rate. Athletes may have athletic heart syndrome, which includes bradycardia as part of the cardiovascular adaptations to training and participation. The word "bradycardia" is from the Greek βραδύς ''bradys'' "slow", and καρδία ''kardia'' "heart". Classification Sinus Atrial bradycardias are divided into three types. The first, respiratory sinus arrhythmia, is usually found in young and healthy adults. Heart rate increases during inhalation and decreases during exhalation. ...
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Diarrhea
Diarrhea, also spelled diarrhoea, is the condition of having at least three loose, liquid, or watery bowel movements each day. It often lasts for a few days and can result in dehydration due to fluid loss. Signs of dehydration often begin with loss of the normal stretchiness of the skin and irritable behaviour. This can progress to decreased urination, loss of skin color, a fast heart rate, and a decrease in responsiveness as it becomes more severe. Loose but non-watery stools in babies who are exclusively breastfed, however, are normal. The most common cause is an infection of the intestines due to either a virus, bacterium, or parasite—a condition also known as gastroenteritis. These infections are often acquired from food or water that has been contaminated by feces, or directly from another person who is infected. The three types of diarrhea are: short duration watery diarrhea, short duration bloody diarrhea, and persistent diarrhea (lasting more than two weeks ...
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