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Chloroprocaine
Chloroprocaine (trade name Nesacaine, Nesacaine-MPF) (often in the hydrochloride salt form as the aforementioned trade names) is a local anesthetic given by injection during surgical procedures and labor and delivery. Chloroprocaine vasodilates; this is in contrast to cocaine which vasoconstricts. Chloroprocaine is an ester anesthetic. Medical uses Chloroprocaine is used for regional anaesthesia including spinal anaesthesia, caudal anaesthesia and epidural anesthesia It is also indicated for local anaesthesia including brachial plexus block, cervical nerve block, occipital nerve block. mandibular nerve block or maxillary nerve block for dental anesthesia, ophthalmic anesthesia via infraorbital nerve block, ulnar nerve block, paravertebral block, intercostal nerve block, sciatic nerve block, stellate ganglion block, lumbar sympathetic block and interdigital block. It is also used for obstetric anesthesia including pudendal nerve block and paracervical block. Chloroprocaine i ...
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Pudendal Nerve Block
Pudendal anesthesia, also known as a pudendal block, or saddle block, is a form of local anesthesia commonly used in the practice of obstetrics to relieve pain during the delivery of baby by forceps. The pudendal nerve block prevents fainting during forceps delivery which was common before pudendal nerve block use was available. The anesthesia is produced by blocking the pudendal nerves near the ischial spine of the pelvis. The ischial spine separates the greater and lesser sciatic foramina at the exit of the bony pelvis. The pudendal block gets its name because a local anesthetic, such as lidocaine or chloroprocaine, is injected into the pudendal canal where the pudendal nerve is located. This allows quick pain relief to the perineum, vulva, and vagina. A pudendal block is usually given in the second stage of labor just before delivery of the baby. It relieves pain around the vagina and rectum as the baby comes down the birth canal. It is also helpful just before an episiotomy ...
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Local Anesthetic
A local anesthetic (LA) is a medication that causes absence of pain sensation. In the context of surgery, a local anesthetic creates an absence of pain in a specific location of the body without a loss of consciousness, as opposed to a general anesthetic. When it is used on specific nerve pathways (local anesthetic nerve block), paralysis (loss of muscle power) also can be achieved. Examples Short Duration & Low Potency Procaine Chloroprocaine Medium Duration & Potency Lidocaine Prilocaine High Duration & Potency Tetracaine Bupivacaine Cinchocaine Ropivacaine Clinical LAs belong to one of two classes: aminoamide and aminoester local anesthetics. Synthetic LAs are structurally related to cocaine. They differ from cocaine mainly in that they have a very low abuse potential and do not produce hypertension or (with few exceptions) vasoconstriction. They are used in various techniques of local anesthesia such as: * Topical anesthesia (surface) * Topical administration ...
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Lidocaine
Lidocaine, also known as lignocaine and sold under the brand name Xylocaine among others, is a local anesthetic of the amino amide type. It is also used to treat ventricular tachycardia. When used for local anaesthesia or in nerve blocks, lidocaine typically begins working within several minutes and lasts for half an hour to three hours. Lidocaine mixtures may also be applied directly to the skin or mucous membranes to numb the area. It is often used mixed with a small amount of adrenaline (epinephrine) to prolong its local effects and to decrease bleeding. If injected intravenously, it may cause cerebral effects such as confusion, changes in vision, numbness, tingling, and vomiting. It can cause low blood pressure and an irregular heart rate. There are concerns that injecting it into a joint can cause problems with the cartilage. It appears to be generally safe for use in pregnancy. A lower dose may be required in those with liver problems. It is generally safe to use in those ...
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Infraorbital Nerve
The infraorbital nerve is a branch of the maxillary nerve, itself a branch of the trigeminal nerve (CN V). It travels through the orbit and enters the infraorbital canal to exit onto the face through the infraorbital foramen. It provides sensory innervation to the skin and mucous membranes around the middle of the face. Structure The infraorbital nerve is a branch of the maxillary nerve (CN V2), itself a branch of the trigeminal nerve (CN V). It travels with the infraorbital artery and vein. It branches from the maxillary nerve in the pterygopalatine fossa and travels through the inferior orbital fissure to enter the orbit. It runs anteriorly along the floor of the orbit in the infraorbital groove to the infraorbital canal of the maxilla. Within the infraorbital canal it has three branches, the posterior superior alveolar nerve, middle superior alveolar nerve and anterior superior alveolar nerve. After traversing the canal it emerges onto the anterior surface of the maxilla thr ...
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Sodium Bisulfate
Sodium bisulfate, also known as sodium hydrogen sulfate, is the sodium salt of the bisulfate anion, with the molecular formula NaHSO4. Sodium bisulfate is an acid salt formed by partial neutralization of sulfuric acid by an equivalent of sodium base, typically in the form of either sodium hydroxide (lye) or sodium chloride (table salt). It is a dry granular product that can be safely shipped and stored. The anhydrous form is hygroscopic. Solutions of sodium bisulfate are acidic, with a 1M solution having a pH of around 1. Production Sodium bisulfate is produced as an intermediate in the Mannheim process, an industrial process involving the reaction of sodium chloride and sulfuric acid: :NaCl + H2SO4 → HCl + NaHSO4 This step is highly exothermic. The liquid sodium bisulfate is sprayed and cooled so that it forms a solid bead. The hydrogen chloride gas is dissolved in water to produce hydrochloric acid as a useful coproduct of the reaction. Although not of commercial inter ...
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Subarachnoid
In anatomy, the meninges (, ''singular:'' meninx ( or ), ) are the three membranes that envelop the brain and spinal cord. In mammals, the meninges are the dura mater, the arachnoid mater, and the pia mater. Cerebrospinal fluid is located in the subarachnoid space between the arachnoid mater and the pia mater. The primary function of the meninges is to protect the central nervous system. Structure Dura mater The dura mater ( la, tough mother) (also rarely called ''meninx fibrosa'' or ''pachymeninx'') is a thick, durable membrane, closest to the skull and vertebrae. The dura mater, the outermost part, is a loosely arranged, fibroelastic layer of cells, characterized by multiple interdigitating cell processes, no extracellular collagen, and significant extracellular spaces. The middle region is a mostly fibrous portion. It consists of two layers: the endosteal layer, which lies closest to the skull, and the inner meningeal layer, which lies closer to the brain. It contains large ...
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Paracervical Block
A paracervical block is an anesthetic procedure used in obstetrics and gynecology, in which a local anesthetic is injected into between two and six sites at a depth of 3–7 mm alongside the vaginal portion of the cervix in the vaginal fornices. It is used for various obstetric and gynecologic procedures, such as hysteroscopy and vacuum aspiration. It is as efficient as intracervical block, according to a study on women undergoing vacuum aspiration with lidocaine as anesthetic agent. Addition of ketorolac Ketorolac, sold under the brand names Toradol, and Biorolac among others, is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain. Specifically it is recommended for moderate to severe pain. Recommended duration of treatment is less ... may offer added benefit of improved pain control. References {{reflist Further reading paracervical block Obstetrical procedures Female genital procedures Regional anesthesia ...
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Obstetric Anesthesia
Obstetric anesthesia or obstetric anesthesiology, also known as ob-gyn anesthesia or ob-gyn anesthesiology, is a sub-specialty of anesthesiology that provides peripartum (time directly preceding, during or following childbirth) pain relief (analgesia) for labor and anesthesia (suppress consciousness) for cesarean deliveries ('C-sections'). Other subspecialty options for anesthesiology include cardiac anesthesiology, pediatric anesthesiology, pain medicine, critical care, neuroanesthesia, regional anesthesia, transplant anesthesia and trauma anesthesia. Scope Obstetric anesthesiologists typically serve as consultants to ob-gyn physicians and provide pain management for both complicated and uncomplicated pregnancies. An obstetric anesthesiologist's practice may consist largely of managing pain during vaginal deliveries and administering anesthesia for cesarean sections; however, the scope is expanding to involve anesthesia for both maternal as well as fetal procedures. Maternal-s ...
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Lumbar
In tetrapod anatomy, lumbar is an adjective that means ''of or pertaining to the abdominal segment of the torso, between the diaphragm and the sacrum.'' The lumbar region is sometimes referred to as the lower spine, or as an area of the back in its proximity. In human anatomy the five lumbar vertebrae (vertebrae in the lumbar region of the back) are the largest and strongest in the movable part of the spinal column, and can be distinguished by the absence of a foramen in the transverse process, and by the absence of facets on the sides of the body. In most mammals, the lumbar region of the spine curves outward. The actual spinal cord terminates between vertebrae one and two of this series, called L1 and L2. The nervous tissue that extends below this point are individual strands that collectively form the cauda equina. In between each lumbar vertebra a nerve root exits, and these nerve roots come together again to form the largest single nerve in the human body, the sciatic n ...
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Stellate Ganglion
The stellate ganglion (or cervicothoracic ganglion) is a sympathetic ganglion formed by the fusion of the inferior cervical ganglion and the first thoracic (superior thoracic sympathetic) ganglion, which exists in 80% of people. Sometimes, the second and the third thoracic ganglia are included in this fusion. The stellate ganglion is relatively big (10–12 x 8–20 mm) compared to much smaller thoracic, lumbar and sacral ganglia, and is polygonal in shape (). Stellate ganglion is located at the level of C7, anterior to the transverse process of C7 and the neck of the first rib, superior to the cervical pleura and just below the subclavian artery. It is superiorly covered by the prevertebral lamina of the cervical fascia and anteriorly in relation with common carotid artery, subclavian artery and the beginning of vertebral artery which sometimes leaves a groove at the apex of this ganglion (this groove can sometimes even separate the stellate ganglion into so called vertebral gangli ...
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Sciatic Nerve Block
A sciatic nerve block is a nerve block that uses local anesthetic to achieve analgesia in the leg. The block works by affecting the sciatic nerve and is used for surgeries at or below the knee. The sciatic nerve is located in the gluteus maximus muscle, where the block is performed. The sciatic nerve can be blocked at different locations. At the popliteal fossa, the sciatic nerve divides into its two branches: The tibial and the common peroneal nerve. If surgery is performed on the ankle, achilles tendon or foot a popliteal block Popliteal refers to anatomical structures located in the back of the knee: *Popliteal artery *Popliteal vein *Popliteal fossa * Popliteal lymph nodes *Popliteus muscle *Popliteal nerves *Popliteal pterygium syndrome Popliteal pterygium syndrome (P ... can be performed, affecting the two branches of the sciatic nerve. It is done above the knee on the posterior leg where the sciatic nerve starts splitting into the common peroneal and tibial nerves. Refe ...
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