China National GeneBank
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China National GeneBank
China National GeneBank or CNGB () is China's first national-level gene storage bank, approved and funded by the Chinese government. Based in the Dapeng Peninsula of Shenzhen, CNGB's mission is to support public welfare, life science research and innovation, as well as industry incubation, through effective bioresource conservation, digitalization and utilization. In 2011 the Chinese National Development and Reform Commission (NDRC), Ministry of Finance, Ministry of Industry and Information Technology, and Ministry of Health and Family Planning approved the establishment of the Centre, entrusting BGI with its construction in a public-private partnership. After 5-years of development the first phase of the centre opened in September 2016, spanning more than 47,500 square meters and including a biorepository, a bioinformatics data center and a living biobank. The Centre also has a Synthetic Biology platform collaborating with Australia's Macquarie University and Harvard on me ...
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Database
In computing, a database is an organized collection of data stored and accessed electronically. Small databases can be stored on a file system, while large databases are hosted on computer clusters or cloud storage. The design of databases spans formal techniques and practical considerations, including data modeling, efficient data representation and storage, query languages, security and privacy of sensitive data, and distributed computing issues, including supporting concurrent access and fault tolerance. A database management system (DBMS) is the software that interacts with end users, applications, and the database itself to capture and analyze the data. The DBMS software additionally encompasses the core facilities provided to administer the database. The sum total of the database, the DBMS and the associated applications can be referred to as a database system. Often the term "database" is also used loosely to refer to any of the DBMS, the database system or an appli ...
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Australia Bioinformatics Resource
The Australia Bioinformatics Resource (EMBL-ABR) (formerly the Bioinformatics Resource Australia - EMBL (BRAEMBL)) was a significant initiative under the associate membership to EMBL. Since 2019, all activities carried out under EMBL-ABR have rolled over into the Bioplatforms Australia (NCRIS-funded) Australian BioCommons, under new funding agreements and led by Associate Professor Andrew Lonie. EMBL-ABR aimed to: # Increase Australia’s capacity to collect, integrate, analyse, exploit, share and archive the large heterogeneous data sets now part of modern life sciences research # Contribute to the development of and provide training in data, tools and platforms to enable Australia’s life science researchers to undertake research in the age of big data # Showcase Australian research and datasets at an international level # Enable engagement in international programs that create, deploy and develop best practice approaches to data management, software tools and methods, compu ...
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Biobank Organizations
A biobank is a type of biorepository that stores biological samples (usually human) for use in research. Biobanks have become an important resource in medical research, supporting many types of contemporary research like genomics and personalized medicine. Biobanks can give researchers access to data representing a large number of people. Samples in biobanks and the data derived from those samples can often be used by multiple researchers for cross purpose research studies. For example, many diseases are associated with single-nucleotide polymorphisms. Genome-wide association studies using data from tens or hundreds of thousands of individuals can identify these genetic associations as potential disease biomarkers. Many researchers struggled to acquire sufficient samples prior to the advent of biobanks. Biobanks have provoked questions on privacy, research ethics, and medical ethics. Viewpoints on what constitutes appropriate biobank ethics diverge. However, a consensus has bee ...
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Biobanks
A biobank is a type of biorepository that stores biological samples (usually human) for use in research. Biobanks have become an important resource in medical research, supporting many types of contemporary research like genomics and personalized medicine. Biobanks can give researchers access to data representing a large number of people. Samples in biobanks and the data derived from those samples can often be used by multiple researchers for cross purpose research studies. For example, many diseases are associated with single-nucleotide polymorphisms. Genome-wide association studies using data from tens or hundreds of thousands of individuals can identify these genetic associations as potential disease biomarkers. Many researchers struggled to acquire sufficient samples prior to the advent of biobanks. Biobanks have provoked questions on privacy, research ethics, and medical ethics. Viewpoints on what constitutes appropriate biobank ethics diverge. However, a consensus has been ...
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Biological Databases
Biological databases are libraries of biological sciences, collected from scientific experiments, published literature, high-throughput experiment technology, and computational analysis. They contain information from research areas including genomics, proteomics, metabolomics, microarray gene expression, and phylogenetics. Information contained in biological databases includes gene function, structure, localization (both cellular and chromosomal), clinical effects of mutations as well as similarities of biological sequences and structures. Biological databases can be classified by the kind of data they collect (see below). Broadly, there are molecular databases (for sequences, molecules, etc.), functional databases (for physiology, enzyme activities, phenotypes, ecology etc), taxonomic databases (for species and other taxonomic ranks), images and other media, or specimens (for museum collections etc.) Databases are important tools in assisting scientists to analyze and explain ...
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Molecular Biology
Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physical structure of biological macromolecules is known as molecular biology. Molecular biology was first described as an approach focused on the underpinnings of biological phenomena - uncovering the structures of biological molecules as well as their interactions, and how these interactions explain observations of classical biology. In 1945 the term molecular biology was used by physicist William Astbury. In 1953 Francis Crick, James Watson, Rosalind Franklin, and colleagues, working at Medical Research Council unit, Cavendish laboratory, Cambridge (now the MRC Laboratory of Molecular Biology), made a double helix model of DNA which changed the entire research scenario. They proposed the DNA structure based on previous research done by Ro ...
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Ruili Botanical Garden
Founded in 2002, Ruili Botanical Garden () and Nanmaohu Park is a botanical garden in Ruili. Located 6 km from the city in Dehong Dai and Jingpo Autonomous Prefecture of Yunnan in the South-West of China near the Myanmar border. The park has more than 5,000 acres of well-preserved native vegetation, mainly monsoon evergreen broad-leaved forest, with more than 1,200 species of tropical and subtropical plants. Research Working with China National GeneBank, BGI and the Forestry Bureau of Ruili, the Botanical Garden is carrying out the Digitalization of Ruili Botanic Garden project, committed to protecting endangered and Chinese endemic plants, by collection, long-term preservation and breeding of germplasm Germplasm are living genetic resources such as seeds or tissues that are maintained for the purpose of animal and plant breeding, preservation, and other research uses. These resources may take the form of seed collections stored in seed banks, t ... resources. Moreover ...
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Swiss Institute Of Bioinformatics
The SIB Swiss Institute of Bioinformatics is an academic not-for-profit foundation which federates bioinformatics activities throughout Switzerland. The institute was established on 30 March 1998 and its mission is to provide core bioinformatics resources to the national and international life science research community in fields such as genomics, proteomics and systems biology as well as to lead and coordinate the field of bioinformatics in Switzerland. In particular, it promotes research, develops databanks and computer technologies, and is involved in teaching and service activities. History The institute was originally created to provide a framework for stable long-term funding for both the Swiss-Prot database and the Swiss EMBnet node. Swiss-Prot in particular went through a major funding crisis in 1996, which led the leaders of the five research groups active in bioinformatics in Geneva and Lausanne, Ron Appel, Amos Bairoch, Philipp Bucher, Victor Jongeneel a ...
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Svalbard Global Seed Vault
The Svalbard Global Seed Vault ( no, Svalbard globale frøhvelv) is a secure backup facility for the world's crop diversity on the Norwegian island of Spitsbergen in the remote Arctic Svalbard archipelago. The Seed Vault provides long-term storage of duplicates of seeds conserved in genebanks around the world. This provides security of the world's food supply against the loss of seeds in genebanks due to mismanagement, accident, equipment failures, funding cuts, war, sabotage, disease and natural disasters. The Seed Vault is managed under terms spelled out in a tripartite agreement among the Norwegian government, the Crop Trust, and the Nordic Genetic Resource Center (NordGen). The Norwegian government entirely funded the Seed Vault's approximately ( in 2008) construction cost. Norway and the Crop Trust pay for operational costs. Storing seeds in the vault is free to depositors. The vault has been depicted in several films and other art forms, including Marcus Paus’ children' ...
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National Center For Biotechnology Information
The National Center for Biotechnology Information (NCBI) is part of the United States National Library of Medicine (NLM), a branch of the National Institutes of Health (NIH). It is approved and funded by the government of the United States. The NCBI is located in Bethesda, Maryland, and was founded in 1988 through legislation sponsored by US Congressman Claude Pepper. The NCBI houses a series of databases relevant to biotechnology and biomedicine and is an important resource for bioinformatics tools and services. Major databases include GenBank for DNA sequences and PubMed, a bibliographic database for biomedical literature. Other databases include the NCBI Epigenomics database. All these databases are available online through the Entrez search engine. NCBI was directed by David Lipman, one of the original authors of the BLAST sequence alignment program and a widely respected figure in bioinformatics. GenBank NCBI had responsibility for making available the GenBank DNA seque ...
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European Bioinformatics Institute
The European Bioinformatics Institute (EMBL-EBI) is an Intergovernmental Organization (IGO) which, as part of the European Molecular Biology Laboratory (EMBL) family, focuses on research and services in bioinformatics. It is located on the Wellcome Genome Campus in Hinxton near Cambridge, and employs over 600 full-time equivalent (FTE) staff. Institute leaders such as Rolf Apweiler, Alex Bateman, Ewan Birney, and Guy Cochrane, an adviser on the National Genomics Data Center Scientific Advisory Board, serve as part of the international research network of the BIG Data Center at the Beijing Institute of Genomics. Additionally, the EMBL-EBI hosts training programs that teach scientists the fundamentals of the work with biological data and promote the plethora of bioinformatic tools available for their research, both EMBL-EBI and non-EMBL-EBI-based. Bioinformatic services One of the roles of the EMBL-EBI is to index and maintain biological data in a set of databases, including E ...
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