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China Basin Landing
China Basin Landing, now referred to as simply China Basin, is an office complex on the border of the South of Market (SoMa) and Mission Bay areas of San Francisco, California.Gordon, Rachel and Bernadette TanseyAnother biotech arrival Sirna Therapeutics moving to S.F.'s Mission Bay area" ''San Francisco Chronicle''. Saturday March 5, 2005. C1. Retrieved on March 3, 2012. The complex has of space.Ross, Andrew S.JPMorgan Chase's sweet deal for China Basin space" ''San Francisco Chronicle''. Thursday January 26, 2012. Retrieved on March 3, 2012. It is the headquarters of Lyft and Dignity Health. History M. Larry Lawrence, a developer from San Diego, California, purchased the site of the China Basin Landing building in 1982. The site had a six story existing structure, the China Basin Building, dating back to the 1920s or earlier. Lawrence spent $40 million to renovate the older building and build a new three story, office facility next to the existing structure. The new o ...
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San Francisco
San Francisco (; Spanish language, Spanish for "Francis of Assisi, Saint Francis"), officially the City and County of San Francisco, is the commercial, financial, and cultural center of Northern California. The city proper is the List of California cities by population, fourth most populous in California and List of United States cities by population, 17th most populous in the United States, with 815,201 residents as of 2021. It covers a land area of , at the end of the San Francisco Peninsula, making it the second most densely populated large U.S. city after New York City, and the County statistics of the United States, fifth most densely populated U.S. county, behind only four of the five New York City boroughs. Among the 91 U.S. cities proper with over 250,000 residents, San Francisco was ranked first by per capita income (at $160,749) and sixth by aggregate income as of 2021. Colloquial nicknames for San Francisco include ''SF'', ''San Fran'', ''The '', ''Frisco'', and '' ...
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McCovey Cove
McCovey Cove is the unofficial name of a section of San Francisco Bay beyond the right field wall of Oracle Park, home of the San Francisco Giants, named after famed Giants first baseman Willie McCovey. The proper name for the cove is China Basin, which is the mouth of Mission Creek as it meets the bay. The cove is bounded along the north by Oracle Park, with a ferry landing and a breakwater at the northeast end. The southern shore is lined by China Basin Park and McCovey Point. To the east, it opens up to San Francisco Bay, while the west end of the cove is bounded by the Lefty O'Doul Bridge, named after San Francisco ballplayer and manager Lefty O'Doul. Naming The name was coined thanks to two sportswriters. Mark Purdy of the ''San Jose Mercury News'' wrote an article suggesting naming the body of water after McCovey, though his original suggestions were 'McCovey Channel,' 'McCovey Stream' or 'McCovey Run.' Purdy then noted the more 'lyrical' name of 'McCovey Cove' was sugge ...
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KEST
KEST (1450 AM) is a brokered time radio station in San Francisco, California. Most of the station's programming is in Asian languages, including Mandarin and Cantonese. It also airs some South Asian, Greek and German programs as well as New Age shows in English. KEST, then called KSOL, was one of the first full time "rhythm and blues" radio stations in the U.S. That station employed disc jockey Sylvester Stewart, later known as Sly Stone of Sly and the Family Stone recording fame. Multicultural Radio owns KEST and numerous ethnic stations across the country, including five in New York City. KEST transmits with 1,000 watts by day and 960 watts at night. It shares a transmitter site with KSFB 1260 AM, off Bayview Park Road, near the Bayshore Freeway (U.S. Route 101) in San Francisco. History KGTT, KGGC and KSAN On , the station first signed on the air. Its first call sign was KGTT. A few years later, it switched its callsign to KGGC, which stood for the Golden Gate Broadca ...
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Public Library Of Science
PLOS (for Public Library of Science; PLoS until 2012 ) is a nonprofit publisher of open-access journals in science, technology, and medicine and other scientific literature, under an open-content license. It was founded in 2000 and launched its first journal, ''PLOS Biology'', in October 2003. As of 2022, PLOS publishes 12 academic journals, including 7 journals indexed within the Science Citation Index Expanded, and consequently 7 journals ranked with an impact factor. PLOS journals are included in the Directory of Open Access Journals (DOAJ). PLOS is also a member of the Open Access Scholarly Publishers Association (OASPA), a participating publisher and supporter of the Initiative for Open Citations, and a member of the Committee on Publication Ethics (COPE). History The Public Library of Science began in 2000 with an online petition initiative by Nobel Prize winner Harold Varmus, formerly director of the National Institutes of Health and at that time directo ...
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Sirna Therapeutics
Sirna Therapeutics, Inc. was a San Francisco, California based biotechnology company that explored the use of RNA interference in human disease therapy. Sirna's development pipeline included several small interfering RNA (siRNA) drugs, thought to stably silence the expression of specific disease-related genes. Sirna's clinical trial of an siRNA-based treatment for age-related macular degeneration was the first such trial for an siRNA drug. Sirna Therapeutics was acquired by Merck & Co. in 2006, the cash transaction deal was worth $1.1 billion.Merck & Co., Inc. Announces Completion of Acquisition of Sirna Therapeutics, Inc.


Synopsys
Synopsys is an American electronic design automation (EDA) company that focuses on silicon design and verification, silicon intellectual property and software security and quality. Products include tools for logic synthesis and physical design of integrated circuits, simulators for development and debugging environments that assist in the design of the logic for chips and computer systems. In recent years, Synopsys has expanded its products and services to include application security testing. Synopsys has gained attention due to its relationship with various Chinese state entities. In 2018, Synopsys formed a partnership with the People's Liberation Army National Defence University and, in 2022, the company came under investigation by the United States Department of Justice for technology transfers to sanctioned entities in China. History Synopsys was founded by Aart J de Geus and David Gregory in 1986 in Research Triangle Park, North Carolina. The company was initially est ...
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Embarcadero Station
Embarcadero station is a combined BART and Muni Metro rapid transit station in the Market Street subway. Located under Market Street between Drumm Street and Beale Street near The Embarcadero, it serves the Financial District neighborhood and surrounding areas. The three-level station has a large fare mezzanine level, with separate platform levels for Muni Metro and BART below. Embarcadero opened in May 1976 – almost two years after service began through the Transbay Tube – as an infill station. With over 42,000 daily passenger entrances on weekdays, Embarcadero and Montgomery Street stations are the two busiest in the BART system. A major Bay Area transit hub, Embarcadero is also served by numerous bus routes of several other agencies which stop above the station and on surrounding streets. Station layout Like the three other shared Muni/BART stations in the Market Street subway, Embarcadero has three underground levels. The uppermost level is a fare mezzanine, with one ...
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Bay Area Rapid Transit
Bay Area Rapid Transit (BART) is a rapid transit system serving the San Francisco Bay Area in California. BART serves 50 stations along six routes on of rapid transit lines, including a spur line in eastern Contra Costa County which uses diesel multiple-unit trains and a automated guideway transit line to the Oakland International Airport. With an average of weekday passengers as of and annual passengers in , BART is the fifth-busiest heavy rail rapid transit system in the United States. BART is operated by the San Francisco Bay Area Rapid Transit District which formed in 1957. The initial system opened in stages from 1972 to 1974. The system was extended most recently in 2020, when Milpitas and Berryessa/North San José stations opened as part of the Silicon Valley BART extension in partnership with the Santa Clara Valley Transportation Authority (VTA). Services BART serves large portions of its three member counties – San Francisco, Alameda, and Contra Costa ...
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San Francisco Ferry Building
The San Francisco Ferry Building is a terminal for ferries that travel across the San Francisco Bay, a food hall and an office building. It is located on The Embarcadero in San Francisco, California and is served by Golden Gate Ferry and San Francisco Bay Ferry routes. On top of the building is a clock tower with four clock dials, each in diameter, which can be seen from Market Street, a main thoroughfare of the city. Designed in 1892 by American architect A. Page Brown in the Beaux-Arts style, the ferry building was completed in 1898. At its opening, it was the largest project undertaken in the city up to that time. One of Brown's design inspirations for the clock tower may have been the current 16th-century iteration of the 12th-century Giralda bell tower in Seville, Spain. The entire length of the building on both frontages is based on an arched arcade. With decreased use since the 1950s, after bridges were constructed to carry transbay traffic and most streetcar r ...
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Financial District, San Francisco
The Financial District is a neighborhood in San Francisco, California, United States, that serves as its main central business district and had 372,829 jobs according to U.S. census tracts as of 2012-2016. It is home to the city's largest concentration of corporate headquarters, law firms, insurance companies, real estate firms, savings and loan banks, and other financial institutions. Multiple Fortune 500 companies headquartered in San Francisco have their offices in the Financial District, including Wells Fargo, Salesforce, PG&E, Uber, Gap, and Williams-Sonoma. Since the 1980s, restrictions on high-rise construction have shifted new development to the adjacent South of Market area surrounding the Transbay Transit Center. This area is sometimes called the South Financial District by real estate developers, or simply included as part of the Financial District itself. However, the COVID-19 pandemic in the United States has accelerated the exodus of business from the downtown core ...
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Muni Metro
Muni Metro is a light rail system serving San Francisco, California, United States. Operated by the San Francisco Municipal Railway (Muni), a part of the San Francisco Municipal Transportation Agency (SFMTA), Muni Metro served an average of 157,700 passengers per weekday in the fourth quarter of 2019, making it the second-busiest light rail system in the United States. Six services – J Church, K Ingleside, L Taraval, M Ocean View, N Judah, and T Third Street run on separate surface alignments and merge into a single downtown tunnel. The supplementary S Shuttle service operates within the tunnel. Muni Metro operates a fleet of 151 Breda high-floor light rail vehicles (LRVs), which are currently being replaced by a fleet of 249 Siemens S200 LRVs. The system has 113 stations, of which 59 (52%) are accessible. Muni Metro is one of the surviving first-generation streetcar systems in North America. The San Francisco Municipal Railway was created in 1909 and opened its first st ...
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Stanford University
Stanford University, officially Leland Stanford Junior University, is a private research university in Stanford, California. The campus occupies , among the largest in the United States, and enrolls over 17,000 students. Stanford is considered among the most prestigious universities in the world. Stanford was founded in 1885 by Leland and Jane Stanford in memory of their only child, Leland Stanford Jr., who had died of typhoid fever at age 15 the previous year. Leland Stanford was a U.S. senator and former governor of California who made his fortune as a railroad tycoon. The school admitted its first students on October 1, 1891, as a coeducational and non-denominational institution. Stanford University struggled financially after the death of Leland Stanford in 1893 and again after much of the campus was damaged by the 1906 San Francisco earthquake. Following World War II, provost of Stanford Frederick Terman inspired and supported faculty and graduates' entrepreneu ...
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