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Chen-Lu Tsou
Zou Chenglu (; 17 May 1923 – 23 November 2006), better known as Chen-Lu Tsou, was a Chinese biochemist. He was a professor of the Shanghai Institute of Biochemistry and later a professor and Deputy Director of the Institute of Biophysics, Chinese Academy of Sciences (CAS). He made important contributions to the synthesis of insulin, and was elected an academician of the CAS and The World Academy of Sciences (TWAS). He won the TWAS Prize in Biology in 1992 for his pioneering study of enzyme inhibition kinetics, and was a six-time laureate of the State Natural Science Award (three times each for First Class and Second Class). His wife, physicist Li Lin, was also an academician of the CAS. Tsou was a strong advocate against academic fraud and pseudoscience, and led a public campaign against what he called "unhealthy practices" such as administrators' interference in scientific research. Early life and education Tsou was born on 17 May 1923 in Qingdao, Shandong province, wi ...
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Zou (surname)
Zou () is the 67th most common Chinese surname, which originated from the state of Zou of the Spring and Autumn period in ancient China. Depending on Chinese variety, Zou can be transliterated as Chow, Chau, Tsau, Trau, Tsou or Chew. It is the 35th name on the ''Hundred Family Surnames The ''Hundred Family Surnames'' (), commonly known as ''Bai Jia Xing'', also translated as ''Hundreds of Chinese Surnames'', is a classic Chinese text composed of common Chinese surnames. An unknown author compiled the book during the Song dyn ...'' poem. Notable people *Zou Yan (鄒衍), Chinese philosopher best known as the representative thinker of the Yin and Yang School (or School of Naturalists) during the Hundred Schools of Thought era *Zou Rong, anti-Qing revolutionary *Zou Zhe: 鄒喆; pinyin: Zōu Zhé; Wade–Giles: Tsou Che 1636-ca. 1708), Chinese painter during the Qing Dynasty *Zou Taofen, journalist *Zou Jiahua, Vice Premier of China, son of Zou Taofen *Chen-Lu Tsou, Chinese bi ...
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Enzyme Inhibition
An enzyme inhibitor is a molecule that binds to an enzyme and blocks its activity. Enzymes are proteins that speed up chemical reactions necessary for life, in which substrate molecules are converted into products. An enzyme facilitates a specific chemical reaction by binding the substrate to its active site, a specialized area on the enzyme that accelerates the most difficult step of the reaction. An enzyme inhibitor stops ("inhibits") this process, either by binding to the enzyme's active site (thus preventing the substrate itself from binding) or by binding to another site on the enzyme such that the enzyme's catalysis of the reaction is blocked. Enzyme inhibitors may bind reversibly or irreversibly. Irreversible inhibitors form a chemical bond with the enzyme such that the enzyme is inhibited until the chemical bond is broken. By contrast, reversible inhibitors bind non-covalently and may spontaneously leave the enzyme, allowing the enzyme to resume its function. Rever ...
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Edward Slater
Edward Charles Slater (16 January 1917 – 26 March 2016), also known as Bill Slater, was an Australian biochemist who spent most of his career at the University of Amsterdam. Early life and education Slater was raised in Australia. He received a training in biochemistry at the Ormond College of the University of Melbourne. In 1946, he moved to Cambridge, where he earned his PhD under the supervision of David Keilin. Career In 1955, Slater joined the medical faculty of the University of Amsterdam, where he remained until retiring in 1985. He is recognised for his contributions to the development of Dutch biochemistry. Slater managed the journal ''Biochimica et Biophysica Acta'', turning it into one of the most influential publications in the field. He wrote a history of the journal, ''Biochimica et biophysica acta: the story of a biochemical journal'', which was published in 1986. He served as the president of the International Union of Biochemistry and Molecular Biology ...
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Cytochrome C
The cytochrome complex, or cyt ''c'', is a small hemeprotein found loosely associated with the inner membrane of the mitochondrion. It belongs to the cytochrome c family of proteins and plays a major role in cell apoptosis. Cytochrome c is highly water-soluble, unlike other cytochromes, and is an essential component of the respiratory electron transport chain, where it carries one electron. It is capable of undergoing oxidation and reduction as its iron atom converts between the ferrous and ferric forms, but does not bind oxygen. It transfers electrons between Complexes III (Coenzyme Q – Cyt c reductase) and IV (Cyt c oxidase). In humans, cytochrome c is encoded by the ''CYCS'' gene. Species distribution Cytochrome c is a highly conserved protein across the spectrum of eukaryotic species, found in plants, animals, fungi, and many unicellular organisms. This, along with its small size (molecular weight about 12,000 daltons), makes it useful in studies of cladistics. Cyt ...
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Haemprotein
A hemeprotein (or haemprotein; also hemoprotein or haemoprotein), or heme protein, is a protein that contains a heme prosthetic group. They are a very large class of metalloproteins. The heme group confers functionality, which can include oxygen carrying, oxygen reduction, electron transfer, and other processes. Heme is bound to the protein either covalently or noncovalently or both. The heme consists of iron cation bound at the center of the conjugate base of the porphyrin, as well as other ligands attached to the "axial sites" of the iron. The porphyrin ring is a planar dianionic, tetradentate ligand. The iron is typically Fe2+ or Fe3+. One or two ligands are attached at the axial sites. The porphyrin ring has 4 nitrogen atoms that bind to the iron, leaving two other coordination positions of the iron available for bonding to the histidine of the protein and a divalent atom. Hemeproteins probably evolved to incorporate the iron atom contained within the protoporphyrin IX rin ...
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Zou Chenglu Aboard A Ship To England
Zou or ZOU may refer to: Places *Zou (state), Chinese state that existed during the Zhou Dynasty *Zou, Ivory Coast, town and sub-prefecture in Ivory Coast *Zou Department of Benin *Zou River of Benin *Zoucheng, formerly Zou County, in Jining, Shandong, China Other uses *Zou (surname) (邹), a Chinese surname * ''Zou'' (TV series), a French animated television series *Zou people, indigenous community living along Indo-Burma frontier *Zimbabwe Open University or "ZOU" See also * Zo language, the language spoken by the Zo people * Zo people, a group of indigenous tribe in Burma and northeast India * Zoo (other) * Zu (other) Zu or ZU may refer to: Arts and entertainment Fictional elements * Zu, a mountain featured in the films ''Zu Warriors from the Magic Mountain'' and ''The Legend of Zu'' * ''ZU'', a " furry" anthology published by MU Press * Zu, a large birdlike mo ... {{Disambiguation, geo Language and nationality disambiguation pages ...
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Molteno Institute For Research In Parasitology
The Molteno Institute for Research in Parasitology was a biological research institute in the University of Cambridge, UK, situated on the Downing Site and founded in response to an appeal by the Quick Professor by a $150 000 gift from Mr & Mrs Percy Alport Molteno in 1919. When it opened in 1921 it was the first parasite biology institute to be established. Between 1947 and 1964 the MRC ( Medical Research Council) Chemotherapy Research Unit was based in 'the Molteno', but research into parasitology continued alongside. Later, between 1968 and 1987, 'the Molteno' became fully occupied by the MRC as their Biochemical Parasitology Unit and totally dedicated to research into parasitology, although the building was still rented from the University of Cambridge. In September 1987 it became part of the University of Cambridge's Pathology Department. Notable workers include Ann Bishop, Douglas Mackay Henderson, David Keilin, Thaddeus Mann and Brunó Ferenc Straub Brunó Ferenc St ...
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Wang Yinglai
Wang Yinglai (; 13 November 1907 – 5 May 2001), also known as Ying-Lai Wang, was a Chinese biochemist recognized as the first person to create synthetic insulin, a major scientific breakthrough that produced a biologically active compound from inorganic chemicals. He was one of the first group of scientists elected to the Chinese Academy of Sciences in 1955. He founded the Shanghai Institute of Biochemistry in 1958 and served as its director until his retirement in 1984. Early life and education Wang was born in Kinmen County (Quemoy), Fujian Province on 13 November 1907, in the final years of the Qing dynasty. He became an orphan at the age of six when his mother died. His father, an Overseas Chinese merchant, had died four years before. Despite the adverse circumstances, he pursued an education throughout the 1920s and 1930s, when China was mired in wars and turmoil. He graduated from the Department of Chemistry of the University of Nanking (Jinling University) and was ...
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University Of Birmingham
, mottoeng = Through efforts to heights , established = 1825 – Birmingham School of Medicine and Surgery1836 – Birmingham Royal School of Medicine and Surgery1843 – Queen's College1875 – Mason Science College1898 – Mason University College1900 – gained university status by royal charter , city = Birmingham , province = West Midlands , country = England, UK , coor = , campus = Urban, suburban , academic_staff = 5,495 (2020) , administrative_staff = , head_label = Visitor , head = The Rt Hon Penny Mordaunt MP , chancellor = Lord Bilimoria , vice_chancellor = Adam Tickell , type = Public , endowment = £134.5 million (2021) , budget = £774.1 million (2020–21) , students = () , undergrad = () , postgrad = () , affiliations = Universitas 21Universities UK EUA ACUSutton 13Russell Group , free_label = , free = , colours = The University , website = , logo = The University of Birmingham (informally Birmingham University) i ...
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World War II
World War II or the Second World War, often abbreviated as WWII or WW2, was a world war that lasted from 1939 to 1945. It involved the vast majority of the world's countries—including all of the great powers—forming two opposing military alliances: the Allies and the Axis powers. World War II was a total war that directly involved more than 100 million personnel from more than 30 countries. The major participants in the war threw their entire economic, industrial, and scientific capabilities behind the war effort, blurring the distinction between civilian and military resources. Aircraft played a major role in the conflict, enabling the strategic bombing of population centres and deploying the only two nuclear weapons ever used in war. World War II was by far the deadliest conflict in human history; it resulted in 70 to 85 million fatalities, mostly among civilians. Tens of millions died due to genocides (including the Holocaust), starvation, ma ...
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Kunming
Kunming (; ), also known as Yunnan-Fu, is the capital and largest city of Yunnan province, China. It is the political, economic, communications and cultural centre of the province as well as the seat of the provincial government. The headquarters of many of Yunnan's large businesses are in Kunming. It was important during World War II as a Chinese military center, American air base, and transport terminus for the Burma Road. In the middle of the Yunnan–Guizhou Plateau, Kunming is at an altitude of above sea level and a latitude just north of the Tropic of Cancer. As of 2020 census, Kunming had a total population of 8,460,088 inhabitants, of whom 5,604,310 lived in its built-up (or metro) area made of all urban districts but Jinning, not conurbated yet. It is at the northern edge of Dian Lake, surrounded by temples and lake-and-limestone hill landscapes. Kunming consists of an old, previously walled city, a modern commercial district, residential zones and university areas. ...
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Second Sino-Japanese War
The Second Sino-Japanese War (1937–1945) or War of Resistance (Chinese term) was a military conflict that was primarily waged between the Republic of China and the Empire of Japan. The war made up the Chinese theater of the wider Pacific Theater of the Second World War. The beginning of the war is conventionally dated to the Marco Polo Bridge Incident on 7 July 1937, when a dispute between Japanese and Chinese troops in Peking escalated into a full-scale invasion. Some Chinese historians believe that the Japanese invasion of Manchuria on 18 September 1931 marks the start of the war. This full-scale war between the Chinese and the Empire of Japan is often regarded as the beginning of World War II in Asia. China fought Japan with aid from Nazi Germany, the Soviet Union, United Kingdom and the United States. After the Japanese attacks on Malaya and Pearl Harbor in 1941, the war merged with other conflicts which are generally categorized under those conflicts of World War II a ...
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