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Charles River Labs
Charles River Laboratories International, Inc., is an American pharmaceutical company specializing in a variety of preclinical and clinical laboratory, gene therapy and cell therapy services for the Pharmaceutical, Medical device and Biotechnology industries. It also supplies assorted biomedical products, outsourcing services, and animals for research and development in the pharmaceutical industry (for example, contract research organization services) and offer support in the fields of basic research, drug discovery, safety and efficacy, clinical support, and manufacturing. The company's broad portfolio allowed them to support the development of approximately 85% of FDA-approved drugs in 2018. Its customers include leading pharmaceutical, biotechnology, agrochemical, government, and academic organization around the globe. The company has over 90 facilities, operates in 20 countries, and employs approximately 18,400 people worldwide. Charles River Laboratories is often criticize ...
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Public Company
A public company is a company whose ownership is organized via shares of stock which are intended to be freely traded on a stock exchange or in over-the-counter markets. A public (publicly traded) company can be listed on a stock exchange (listed company), which facilitates the trade of shares, or not (unlisted public company). In some jurisdictions, public companies over a certain size must be listed on an exchange. In most cases, public companies are ''private'' enterprises in the ''private'' sector, and "public" emphasizes their reporting and trading on the public markets. Public companies are formed within the legal systems of particular states, and therefore have associations and formal designations which are distinct and separate in the polity in which they reside. In the United States, for example, a public company is usually a type of corporation (though a corporation need not be a public company), in the United Kingdom it is usually a public limited company (plc), i ...
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Contract Research Organization
In the life sciences, a contract research organization (CRO) is a company that provides support to the pharmaceutical, biotechnology, and medical device industries in the form of research services outsourced on a contract basis. A CRO may provide such services as biopharmaceutical development, biological assay development, commercialization, clinical development, clinical trials management, pharmacovigilance, outcomes research, and Real world evidence. CROs are designed to reduce costs for companies developing new medicines and drugs in niche markets. They aim to simplify entry into drug markets, and simplify development, as the need for large pharmaceutical companies to do everything ‘in house’ is now redundant. CROs also support foundations, research institutions, and universities, in addition to governmental organizations (such as the NIH, EMA, etc.). Many CROs specifically provide clinical-study and clinical-trial support for drugs and/or medical devices. However, ...
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RiskMetrics
The RiskMetrics variance model (also known as exponential smoother) was first established in 1989, when Sir Dennis Weatherstone, the new chairman of J.P. Morgan, asked for a daily report measuring and explaining the risks of his firm. Nearly four years later in 1992, J.P. Morgan launched the RiskMetrics methodology to the marketplace, making the substantive research and analysis that satisfied Sir Dennis Weatherstone's request freely available to all market participants. In 1998, as client demand for the group's risk management expertise exceeded the firm's internal risk management resources, the Corporate Risk Management Department was spun off from J.P. Morgan as RiskMetrics Group with 23 founding employees. The RiskMetrics technical document was revised in 1996. In 2001, it was revised again in ''Return to RiskMetrics''. In 2006, a new method for modeling risk factor returns was introduced (RM2006). On 25 January 2008, RiskMetrics Group listed on the New York Stock Exchange ...
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Neuberger Berman
Neuberger Berman Group LLC is a private, independent, employee-owned investment management firm. The firm manages equities, fixed income, private equity and hedge fund portfolios for global institutional investors, advisors and high-net-worth individuals. Overview Founded in 1939, Neuberger Berman is a privately held asset management firm, which is 100% owned by its employees. It serves pension plans, charitable organizations, sovereign wealth funds and other institutions, as well as high-net-worth individuals and mutual fund investors, both directly and through financial intermediaries and other partners. The firm has a broad range of investment capabilities, which have enabled it to win numerous public strategic partnership mandates with both leading institutional pension plans and major financial institutions. For its private clients, Neuberger Berman also provides financial planning, fiduciary services, and trust services. Known as a firm of investors, the firm has maintaine ...
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JANA Partners
JANA Partners LLC ("JANA" or "JANA Partners") is an investment manager specializing in event-driven investing. It was founded in 2001 by Barry Rosenstein. JANA engages in traditional shareholder activism and socially responsible investing. History In the 1980s Barry Rosenstein worked with Asher Edelman. In 2001 Rosenstein founded JANA Partners. He began the firm in 2001 with $35 million, making it into a shareholder watchdog. Investment strategies Activist investing As an activist investor JANA Partners buys large numbers of shares in companies that it believes are underperforming, and then encourages the companies to make the changes JANA believes are needed to improve performance. The hedge fund has made activist investments in Apple Inc., Tiffany's, Whole Foods, ConAgra, PetSmart, Walgreens Boots Alliance, Apache, URS, Safeway, Ashland, Marathon Petroleum, McGraw Hill, CNET, and Kerr-McGee. In July 2014, JANA announced a 10% share in Petsmart, despite the company's po ...
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Relational Investors
{{Infobox company , name = Relational Investors LLC , type = Private , foundation = 1996 , location = San Diego California , founder = Ralph V. Whitworth, Co-Founder David H. Batchelder, Co-Founder , industry = Financial services , products = Asset Managements, Activist Investor , assets = $6 billion , homepage www.rillc.com Relational Investors is an activist investment fund based in San Diego, California. Founded in 1996 by Ralph V. Whitworth, the fund has $6 Billion in assets under management. The firm primarily invests in value stocks of companies with market capitalization of over $5 billion while charging a 1% management fee and a 20% incentive fee on returns above the S&P 500. The fund tends to invest in specific target companies with the intent of exerting influence on management while getting its own board members elected. Typically, the fund looks for businesses with strong fundamentals and cash flows but are trading below their intrinsic value due to imprope ...
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WuXi PharmaTech
WuXi AppTec (WuXi pronounced ''Wu-shee'') is a global pharmaceutical, biopharmaceutical, and medical device company. The company covers the development cycle through five core operations, including small molecule R&D and manufacturing, biologics R&D and manufacturing, cell therapy and gene therapy R&D and manufacturing, medical device testing, and molecular testing and genomics. History WuXi's founder is Dr. Ge Li, an organic chemist, who founded WuXi PharmaTech in Shanghai in December 2000. WuXi established services in synthetic chemistry in 2001, manufacturing process development in 2003, research manufacturing in 2004, bioanalytical services in 2005, service biology in 2006, and toxicology and formulation in 2007. On December 14, 2006, WuXi PharmaTech announced that it was ranked 173rd on the Deloitte Technology Fast 500 Asia Pacific 2006. The company opened chemistry facilities in Tianjin in 2007. In 2008, WuXi PharmaTech acquired AppTec Laboratory Services Inc., a US-based ...
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Quotient Bioresearch
In arithmetic, a quotient (from lat, quotiens 'how many times', pronounced ) is a quantity produced by the division of two numbers. The quotient has widespread use throughout mathematics, and is commonly referred to as the integer part of a division (in the case of Euclidean division), or as a fraction or a ratio (in the case of proper division). For example, when dividing 20 (the ''dividend'') by 3 (the ''divisor''), the ''quotient'' is "6 with a remainder of 2" in the Euclidean division sense, and 6\tfrac in the proper division sense. In the second sense, a quotient is simply the ratio of a dividend to its divisor. Notation The quotient is most frequently encountered as two numbers, or two variables, divided by a horizontal line. The words "dividend" and "divisor" refer to each individual part, while the word "quotient" refers to the whole. \dfrac \quad \begin & \leftarrow \text \\ & \leftarrow \text \end \Biggr \} \leftarrow \text Integer part definition The quo ...
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Edinburgh
Edinburgh ( ; gd, Dùn Èideann ) is the capital city of Scotland and one of its 32 Council areas of Scotland, council areas. Historically part of the county of Midlothian (interchangeably Edinburghshire before 1921), it is located in Lothian on the southern shore of the Firth of Forth. Edinburgh is Scotland's List of towns and cities in Scotland by population, second-most populous city, after Glasgow, and the List of cities in the United Kingdom, seventh-most populous city in the United Kingdom. Recognised as the capital of Scotland since at least the 15th century, Edinburgh is the seat of the Scottish Government, the Scottish Parliament and the Courts of Scotland, highest courts in Scotland. The city's Holyrood Palace, Palace of Holyroodhouse is the official residence of the Monarchy of the United Kingdom, British monarchy in Scotland. The city has long been a centre of education, particularly in the fields of medicine, Scots law, Scottish law, literature, philosophy, the sc ...
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Jackson Laboratory
The Jackson Laboratory (often abbreviated as JAX) is an independent, non-profit biomedical research institution which was founded by a eugenicist. It employs more than 3,000 employees in Bar Harbor, Maine; Sacramento, California; Farmington, Connecticut; Shanghai, China; and Yokohama, Japan. The institution is a National Cancer Institute-designated Cancer Center and has NIH Centers of Excellence in aging and systems genetics. The mission of The Jackson Laboratory is "to discover the genetic basis for preventing, treating and curing human diseases, and to enable research and education for the global biomedical community." The laboratory is also the world's source for more than 8,000 strains of genetically defined mice, home of the Mouse Genome Informatics database, and is an international hub for scientific courses, conferences, training and education. Major research areas Jackson Laboratory's research, represented by the activities of more than 60 laboratories, performs resear ...
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Hollister, California
Hollister is a city in and the county seat of San Benito County, located in the Central Coast region of California. With a 2020 United States census population of 41,678, Hollister is one of the largest cities in the Monterey Bay Area and a member of the Association of Monterey Bay Area Governments. The city is an agricultural town known primarily for its local Blenheim apricots, olive oil, vineyards, pomegranates, and chocolate. History The area of modern-day Hollister was historically inhabited by the Mutsun band of the Ohlone Native Americans. With the construction of Mission San Juan Bautista in 1797, the Ohlone were forced into the California mission system. The town of Hollister was founded on November 19, 1868, by William Welles Hollister on the grounds of the former Mexican land-grant Rancho San Justo. At the time, Hollister was located within Monterey County, until San Benito County was formed by the California Legislature in 1874 from portions of Monterey, Merc ...
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San Diego
San Diego ( , ; ) is a city on the Pacific Ocean coast of Southern California located immediately adjacent to the Mexico–United States border. With a 2020 population of 1,386,932, it is the List of United States cities by population, eighth most populous city in the United States and the county seat, seat of San Diego County, the List of the most populous counties in the United States, fifth most populous county in the United States, with 3,338,330 estimated residents as of 2019. The city is known for its mild year-round climate, natural deep-water harbor, extensive beaches and parks, long association with the United States Navy, and recent emergence as a healthcare and biotechnology development center. San Diego is the List of municipalities in California, second largest city in the U.S. state, state of California, after Los Angeles. Historically home to the Kumeyaay people, San Diego is frequently referred to as the "Birthplace of California", as it was the first site vi ...
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