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Charles Alderson Janeway
Charles Alderson Janeway (1909 in New York City – 1981 in Weston, Massachusetts) was an American pediatrician, medical professor, and clinical researcher. Janeway was physician in chief from 1946 to 1976 at Children's Hospital Boston. He also was Thomas Morgan Rotch Professor of Pediatrics at Harvard Medical School. As a clinical researcher, he discovered the first immunodeficiency disease.Haggerty, RJ, and Lovejoy Jr., FH.(2007) ''Charles A. Janeway: Pediatrician to the World's Children'' Cambridge, Massachusetts: Harvard University Press. () According to a 2007 biography by physicians Robert J. Haggerty and Frederick H. Lovejoy Jr.: "Janeway built the first department of pediatrics in the nation with subspecialties based upon the new developments in basic sciences. Janeway and his colleagues defined the gamma globulin disorders that resulted in children's increased susceptibility to infections and associated arthritic disorders. Janeway was the most visible U.S. pediatri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Weston, Massachusetts
Weston is a town in Middlesex County, Massachusetts, Middlesex County, Massachusetts, about 15 miles west of Boston. At the time of the 2020 United States Census, the population of Weston was 11,851. Weston was incorporated in 1713, and protection of the town's historic resources is driven by the Weston Historical Commission and Weston Historical Society. The town has one Local Historic District, 10 National Register Districts, 26 Historic Areas, and seven houses individually listed on the National Register of Historic Places. Weston's predominance as a residential community is reflected in its population density, which is among the lowest of Boston's suburbs near or within Massachusetts Route 128, Route 128. More than 2,000 acres, or 18 percent of the town's total acreage, have been preserved as parks, fields, wetlands, and forests, with 90 miles of trails for hiking, horseback riding, and cross-country skiing. Thirty-seven scenic roads, as defined by Massachusetts law, maintain ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Janeway Lesions
Janeway lesions are rare, non-Tenderness (medicine), tender, small erythematous or haemorrhagic macule, macular, papule, papular or Nodule (medicine), nodular lesions on the palms or Sole (foot), soles only a few millimeters in diameter that are associated with infective endocarditis and often indistinguishable from Osler's nodes. Definition Janeway lesions are painless, frequently haemorrhagic lesions seen most commonly on the palms and soles, particularly on the base of the thumb and little finger, and seen in infective endocarditis. Differential Osler's nodes and Janeway lesions are similar and point to the same diagnostic conclusion. The most significant difference between the two is that Osler's nodes present with tenderness, while Janeway lesions do not. Osler's nodes are thought to be due to immunologic phenomenon where deposition of immune complexes provoke inflammatory response, leading to swelling, redness and pain. On the contrary, Janeway lesions are thought to be due t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Milton Academy Alumni
Milton may refer to: Names * Milton (surname), a surname (and list of people with that surname) ** John Milton (1608–1674), English poet * Milton (given name) ** Milton Friedman (1912–2006), Nobel laureate in Economics, author of '' Free to Choose'' Places Australia * Milton, New South Wales * Milton, Queensland, a suburb of Brisbane ** Milton Courts, a tennis centre ** Milton House, Milton, a heritage-listed house ** Milton railway station, Brisbane ** Milton Reach, a reach of the Brisbane River ** Milton Road, an arterial road in Brisbane Canada * Milton, Newfoundland and Labrador * Milton, Nova Scotia in the Region of Queens Municipality * Milton, Ontario ** Milton line, a commuter train line ** Milton GO Station * Milton (electoral district), Ontario ** Milton (provincial electoral district), Ontario * Beaverton, Ontario a community in Durham Region and renamed as Beaverton in 1835 * Rural Municipality of Milton No. 292, Saskatchewan New Zealand * Milton, Ne ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Johns Hopkins University Alumni
Johns may refer to: Places * Johns, Mississippi, an unincorporated community * Johns, Oklahoma, United States, a community * Johns Creek (Chattahoochee River), Georgia, United States * Johns Island (other), islands in Canada and the United States * Johns Mountain, a summit in Georgia * Johns River (other) * Johns River (Vermont), a tributary of Lake Memphremagog * Johns Township, Appanoose County, Iowa, United States Other uses * Johns (surname) * Johns Hopkins (1795–1873), American entrepreneur, investor and philanthropist * ''johns'' (film), a 1996 film starring David Arquette and Lukas Haas See also * John (other) * Justice Johns (other) * {{disambig, geo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yale University Alumni
Yale University is a private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the third-oldest institution of higher education in the United States and among the most prestigious in the world. It is a member of the Ivy League. Chartered by the Connecticut Colony, the Collegiate School was established in 1701 by clergy to educate Congregational ministers before moving to New Haven in 1716. Originally restricted to theology and sacred languages, the curriculum began to incorporate humanities and sciences by the time of the American Revolution. In the 19th century, the college expanded into graduate and professional instruction, awarding the first PhD in the United States in 1861 and organizing as a university in 1887. Yale's faculty and student populations grew after 1890 with rapid expansion of the physical campus and scientific research. Yale is organized into fourteen constituent schools: the original undergraduate colleg ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1981 Deaths
Events January * January 1 ** Greece enters the European Economic Community, predecessor of the European Union. ** Palau becomes a self-governing territory. * January 10 – Salvadoran Civil War: The Farabundo Martí National Liberation Front, FMLN launches its first major offensive, gaining control of most of Morazán Department, Morazán and Chalatenango Department, Chalatenango departments. * January 15 – Pope John Paul II receives a delegation led by Polish Solidarity (Polish trade union), Solidarity leader Lech Wałęsa at the Vatican City, Vatican. * January 20 – Iran releases the 52 Americans held for 444 days, minutes after Ronald Reagan is First inauguration of Ronald Reagan, sworn in as the 40th President of the United States, ending the Iran hostage crisis. * January 21 – The first DMC DeLorean, DeLorean automobile, a stainless steel sports car with gull-wing doors, rolls off the production line in Dunmurry, Northern Ireland. * January 24 – An 1981 Dawu ea ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1909 Births
Nineteen or 19 may refer to: * 19 (number), the natural number following 18 and preceding 20 * one of the years 19 BC, AD 19, 1919, 2019 Films * ''19'' (film), a 2001 Japanese film * ''Nineteen'' (film), a 1987 science fiction film Music * 19 (band), a Japanese pop music duo Albums * ''19'' (Adele album), 2008 * ''19'', a 2003 album by Alsou * ''19'', a 2006 album by Evan Yo * ''19'', a 2018 album by MHD * ''19'', one half of the double album ''63/19'' by Kool A.D. * ''Number Nineteen'', a 1971 album by American jazz pianist Mal Waldron * ''XIX'' (EP), a 2019 EP by 1the9 Songs * "19" (song), a 1985 song by British musician Paul Hardcastle. * "Nineteen", a song by Bad4Good from the 1992 album '' Refugee'' * "Nineteen", a song by Karma to Burn from the 2001 album ''Almost Heathen''. * "Nineteen" (song), a 2007 song by American singer Billy Ray Cyrus. * "Nineteen", a song by Tegan and Sara from the 2007 album '' The Con''. * "XIX" (song), a 2014 song by Slipk ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Innate Immune Response
The innate, or nonspecific, immune system is one of the two main immunity strategies (the other being the adaptive immune system) in vertebrates. The innate immune system is an older evolutionary defense strategy, relatively speaking, and is the dominant immune system response found in plants, fungi, insects, and primitive multicellular organisms (see Beyond vertebrates).. The major functions of the innate immune system are to: * recruit immune cells to infection sites by producing chemical factors, including chemical mediators called cytokines * activate the complement cascade to identify bacteria, activate cells, and promote clearance of antibody complexes or dead cells * identify and remove foreign substances present in organs, tissues, blood and lymph, by specialized white blood cells * activate the adaptive immune system through antigen presentation * act as a physical and chemical barrier to infectious agents; via physical measures such as skin and chemical measures such a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Academy Of Sciences
The National Academy of Sciences (NAS) is a United States nonprofit, non-governmental organization. NAS is part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Engineering (NAE) and the National Academy of Medicine (NAM). As a national academy, new members of the organization are elected annually by current members, based on their distinguished and continuing achievements in original research. Election to the National Academy is one of the highest honors in the scientific field. Members of the National Academy of Sciences serve '' pro bono'' as "advisers to the nation" on science, engineering, and medicine. The group holds a congressional charter under Title 36 of the United States Code. Founded in 1863 as a result of an Act of Congress that was approved by Abraham Lincoln, the NAS is charged with "providing independent, objective advice to the nation on matters related to science and technology. ... to provide scien ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Charles Janeway
Charles Alderson Janeway, Jr. (1943–2003) was a noted immunologist who helped create the modern field of innate immunity. A member of the National Academy of Sciences, he held a faculty position at Yale University's Medical School and was an Howard Hughes Medical Institute Investigator. Early life Born in Boston on February 5, 1943, to Charles A. and Elizabeth B. Janeway, Charles Janeway was raised in Weston, Massachusetts. He was educated at Phillips Exeter Academy in New Hampshire, and Harvard College, where he graduated summa cum laude in 1963 with a bachelor's degree in chemistry. His interest in medicine was inspired by his parents: his father Charles Alderson Janeway was physician-in-chief at Boston Children's Hospital from 1946 to 1974 and his mother was a social worker at the Boston Lying-In Hospital. By earning his medical degree from Harvard Medical School in 1969, Janeway joined a long family line of prominent physicians. In addition to his father, his gra ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Johns Hopkins University School Of Medicine
The Johns Hopkins University School of Medicine (JHUSOM) is the medical school of Johns Hopkins University, a private research university in Baltimore, Maryland. Founded in 1893, the School of Medicine shares a campus with the Johns Hopkins Hospital and Johns Hopkins Children's Center, established in 1889. It has consistently ranked among the top medical schools in the United States in terms of the number/amount of research grants/funding awarded by the National Institutes of Health, among other measures. History The founding physicians (the "Four Doctors") of the Johns Hopkins School of Medicine included pathologist William Henry Welch (1850–1934), the first dean of the school and a mentor to generations of research scientists; a Canadian, internist Sir William Osler (1849–1919), regarded as the ''Father of Modern Medicine'', having been perhaps the most influential physician of the late 19th and early 20th centuries as author of '' The Principles and Practice of Medicine'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Skull And Bones
Skull and Bones, also known as The Order, Order 322 or The Brotherhood of Death, is an undergraduate senior secret student society at Yale University in New Haven, Connecticut. The oldest senior class society at the university, Skull and Bones has become a cultural institution known for its powerful alumni and various conspiracy theories. It is one of the "Big Three" societies at Yale, the other two being Scroll and Key and Wolf's Head. The society's alumni organization, the Russell Trust Association, owns the organization's real estate and oversees the membership. The society is known informally as "Bones," and members are known as "Bonesmen," "Members of The Order" or "Initiated to The Order." History Skull and Bones was founded in 1832 after a dispute among Yale debating societies Linonia, Brothers in Unity, and the Calliopean Society over that season's Phi Beta Kappa awards. William Huntington Russell and Alphonso Taft co-founded "the Order of the Skull and Bones". Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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