Carl Voegtlin
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Carl Voegtlin
Carl Voegtlin (July 28, 1879 – April 9, 1960), also Karl Voegtlin, was a Swiss-American pharmacologist, organic chemist, and the first director of the U.S. National Cancer Institute. He is known for his research into the biochemical effects of cancer, contributions to the pharmacology of arsenicals and the discovery, with Homer Smith, of mapharsen as the active agent in Paul Ehrlich's Salvarsan. Education and career Voegtlin was born in Zofingen, Switzerland and grew up in Basel, Switzerland. He studied preclinical science at the University of Basel, chemistry and physics at the University of Munich, and also attended University of Geneva, where he worked with the German chemist Carl Graebe. He obtained a doctorate under the supervision of Ludwig Gattermann at the University of Freiburg, Germany in 1902, with a thesis entitled ''Beiträge zur Kenntnis des Phenyläthers und seiner Homologen'' (Contribution to the study of phenylether and its homologues). In 1903 and 1 ...
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Zofingen, Switzerland
Zofingen (french: Zofingue) is a city in the canton of Aargau in Switzerland. It is the capital of the district of Zofingen. Zofingen is a walled city and home of an ancient monastic settlement. History In ancient times Zofingen was a settlement of the Celtic Helvetii. In later times the Romans built a manor. The Alemanni settled in the 6th century and formed one of the oldest parishes in Aargau. In the 11th century the House of Frohburg founded a canons monastery. The town was founded in 1201 by the counts of Frohburg. 1231 was the first written mention of Zofingen, which in 1299 came in the possession of the Habsburgs. In 1415 the Bernese conquered the city and in 1528 they introduced the Reformation. Since 1803 Zofingen has belonged to the canton of Aargau and has become a regional center. The neighboring Mühlethal was incorporated in 2002. Geography Zofingen has an area, , of . Of this area, or 18.8% is used for agricultural purposes, while or 47.3% is forested. Of t ...
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William Henry Perkin Jr
William is a masculine given name of Norman French origin.Hanks, Hardcastle and Hodges, ''Oxford Dictionary of First Names'', Oxford University Press, 2nd edition, , p. 276. It became very popular in the English language after the Norman conquest of England in 1066,All Things William"Meaning & Origin of the Name"/ref> and remained so throughout the Middle Ages and into the modern era. It is sometimes abbreviated "Wm." Shortened familiar versions in English include Will, Wills, Willy, Willie, Liam, Bill, and Billy. A common Irish form is Liam. Scottish diminutives include Wull, Willie or Wullie (as in Oor Wullie or the play ''Douglas''). Female forms are Willa, Willemina, Wilma and Wilhelmina. Etymology William is related to the German given name ''Wilhelm''. Both ultimately descend from Proto-Germanic ''*Wiljahelmaz'', with a direct cognate also in the Old Norse name ''Vilhjalmr'' and a West Germanic borrowing into Medieval Latin ''Willelmus''. The Proto-Germanic name is a ...
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American Society For Pharmacology And Experimental Therapeutics
The American Society for Pharmacology and Experimental Therapeutics (ASPET) is a scientific society founded in late 1908 by John Jacob Abel of Johns Hopkins University (also the founder of the American Society for Biochemistry and Molecular Biology), with the aim of promoting the growth of pharmacological research. Many society members are researchers in basic and clinical pharmacology who help develop disease-fighting medications and therapeutics. ASPET is one of the constituent societies of the Federation of American Societies for Experimental Biology (FASEB). The society's headquarters are in Rockville, MD. The current president is Michael F. Jarvis. Publications The society publishes three research journals and a review journal: the ''Journal of Pharmacology and Experimental Therapeutics'', ''Drug Metabolism and Disposition'', ''Molecular Pharmacology'', and ''Pharmacological Reviews'' Starting in 2012 these publications are only offered online. The society copublishes a who ...
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American Society Of Brewing Chemists
The American Society of Brewing Chemists (ASBC) is a professional organization of scientists and technical professionals in the brewing, malting, and allied industries. It publishes an journal A journal, from the Old French ''journal'' (meaning "daily"), may refer to: *Bullet journal, a method of personal organization *Diary, a record of what happened over the course of a day or other period *Daybook, also known as a general journal, a ..., the Journal of the American Society of Brewing Chemists'. External linksASBC Website Beer organizations Chemistry societies {{sci-org-stub ...
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American Physiological Society
The American Physiological Society is a non-profit professional society for physiologists. It has nearly 10,000 members, most of whom hold doctoral degrees in medicine, physiology or other health professions. Its mission is to support research and education in the physiological sciences. The society publishes 16 peer reviewed journals, sponsors scientific conferences, and sponsors awards to further this mission. Governance Since it was founded in 1887, the APS has had 93 presidents lead the organization, beginning with founder Henry Bowditch and continuing through its current president, Linda C. Samuelson. The APS is governed by an elected Council consisting of the president, the president-elect, the immediate past president, and nine councilors. Management of the affairs of the society is the responsibility of a full-time executive director, appointed by and responsible to the Council. The society maintains a staff and offices in Rockville, Maryland. It conducts its operation ...
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Manhattan District
The Manhattan Project was a research and development undertaking during World War II that produced the first nuclear weapons. It was led by the United States with the support of the United Kingdom and Canada. From 1942 to 1946, the project was under the direction of Major General Leslie Groves of the U.S. Army Corps of Engineers. Nuclear physicist Robert Oppenheimer was the director of the Los Alamos Laboratory that designed the actual bombs. The Army component of the project was designated the Manhattan District as its first headquarters were in Manhattan; the placename gradually superseded the official codename, Development of Substitute Materials, for the entire project. Along the way, the project absorbed its earlier British counterpart, Tube Alloys. The Manhattan Project began modestly in 1939, but grew to employ more than 130,000 people and cost nearly US$2 billion (equivalent to about $ billion in ). Over 90 percent of the cost was for building factories and t ...
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University Of Rochester Medical School
The University of Rochester Medical Center (URMC), now known as UR Medicine, is located in Rochester, New York, is one of the main campuses of the University of Rochester and comprises the university's primary medical education, research and patient care facilities. Schools and facilities URMC is one of the largest facilities for medical treatment and research in Upstate New York and includes a regional Prenatal Center, Trauma Center, Burn Center, Cancer Center, an Epilepsy Center, Psychiatric/Behavioral Health Emergency and treatment departments, Liver Transplant Center and Cardiac Transplant Center and also includes a major AIDS Treatment Center and an NIH-designated AIDS Vaccine Evaluation Unit. A large portion of the university's biomedical research is conducted in the Arthur Kornberg Medical Research Building and the Aab Institute of Biomedical Sciences. In January 2008, the University of Rochester announced a $500 million strategic plan geared toward expansion in research ...
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New York University
New York University (NYU) is a private research university in New York City. Chartered in 1831 by the New York State Legislature, NYU was founded by a group of New Yorkers led by then-Secretary of the Treasury Albert Gallatin. In 1832, the non-denominational all-male institution began its first classes near City Hall based on a curriculum focused on a secular education. The university moved in 1833 and has maintained its main campus in Greenwich Village surrounding Washington Square Park. Since then, the university has added an engineering school in Brooklyn's MetroTech Center and graduate schools throughout Manhattan. NYU has become the largest private university in the United States by enrollment, with a total of 51,848 enrolled students, including 26,733 undergraduate students and 25,115 graduate students, in 2019. NYU also receives the most applications of any private institution in the United States and admission is considered highly selective. NYU is organized int ...
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Bellevue Hospital Medical College
NYU Grossman School of Medicine is a medical school of New York University, a private research university in New York City. It was founded in 1841 and is one of two medical schools of the university, with the other being the Long Island School of Medicine. NYU Grossman School of Medicine is part of NYU Langone Health, named after Kenneth Langone, the investment banker and financial backer of The Home Depot. In 2022, U.S''. News & World Report'' ranked NYU Grossman School of Medicine as No. 2 “Best Graduate Schools". History New York University College of Medicine was established in 1841. The medical school merged with Bellevue Hospital Medical College in 1898 to form the University and Bellevue Hospital Medical College. The name NYU Grossman School of Medicine was adopted in 2019. NYU Grossman School of Medicine is home to many key advancements in medical education. In 1854, human dissection in New York was legalized due to efforts of the faculty. In 1866, NYU professors pro ...
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Chemotherapy
Chemotherapy (often abbreviated to chemo and sometimes CTX or CTx) is a type of cancer treatment that uses one or more anti-cancer drugs (chemotherapeutic agents or alkylating agents) as part of a standardized chemotherapy regimen. Chemotherapy may be given with a curative intent (which almost always involves combinations of drugs) or it may aim to prolong life or to reduce symptoms ( palliative chemotherapy). Chemotherapy is one of the major categories of the medical discipline specifically devoted to pharmacotherapy for cancer, which is called ''medical oncology''. The term ''chemotherapy'' has come to connote non-specific usage of intracellular poisons to inhibit mitosis (cell division) or induce DNA damage, which is why inhibition of DNA repair can augment chemotherapy. The connotation of the word chemotherapy excludes more selective agents that block extracellular signals (signal transduction). The development of therapies with specific molecular or genetic targets, wh ...
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National Institutes Of Health
The National Institutes of Health, commonly referred to as NIH (with each letter pronounced individually), is the primary agency of the United States government responsible for biomedical and public health research. It was founded in the late 1880s and is now part of the United States Department of Health and Human Services. The majority of NIH facilities are located in Bethesda, Maryland, and other nearby suburbs of the Washington metropolitan area, with other primary facilities in the Research Triangle Park in North Carolina and smaller satellite facilities located around the United States. The NIH conducts its own scientific research through the NIH Intramural Research Program (IRP) and provides major biomedical research funding to non-NIH research facilities through its Extramural Research Program. , the IRP had 1,200 principal investigators and more than 4,000 postdoctoral fellows in basic, translational, and clinical research, being the largest biomedical research instit ...
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Reid Hunt
Reid Hunt (1870–1948), was an American pharmacologist, known for his work on adrenal glands The adrenal glands (also known as suprarenal glands) are endocrine glands that produce a variety of hormones including adrenaline and the steroids aldosterone and cortisol. They are found above the kidneys. Each gland has an outer cortex which ...; where he postulated that extracts from which cause rise in blood pressure due to its content of adrenaline. When he removed the adrenaline from the extract and he found that it causes fall in blood pressure, which he concluded was due to a derivative of choline, later on known as acetylcholine. Research Methyl alcohol toxicity Activity of acetylcholine Thyroid gland During the study of thyroid gland iodine content and its physiological activity he demonstrated the presence of thyroid hormone in the human blood. Studies involving acetonitrile showed that the poisoning is mainly due to the hydrocyanic acid liberated in the org ...
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