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Carapichea Ipecacuanha
''Carapichea ipecacuanha'' is a species of flowering plant in the family Rubiaceae. It is native to Costa Rica, Nicaragua, Panama, Colombia, and Brazil. Its common name, ipecacuanha (), is derived from the Tupi ''ipega'kwãi'', or "road-side sick-making plant". The plant has been discussed under a variety of synonyms over the years by various botanists. The roots were used to make syrup of ipecac, a powerful emetic, a longtime over-the-counter medicine no longer approved for medical use in the West for lack of evidence of safety and efficacy. An example of emetic compound from the roots is emetine. Description Ipecacuanha is a slow-growing plant, which reduces its commercial appeal as a crop plant. It is seldom cultivated in South America but it has been cultivated in India and elsewhere. The root of ipecacuanha has been used in preparation of the medicament, the syrup, is simple or divided into a few branches, flexuous, and composed of rings of various size. It is somewhat fl ...
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Ipecac
Syrup of ipecac (), or simply ipecac, is a drug that was once widely used as an expectorant (in low doses) and a rapid-acting emetic (in higher doses). It is obtained from the dried rhizome and roots of the ipecacuanha plant (''Carapichea ipecacuanha''), from which it derives its name. It is no longer used in medicine. In particular, the rapidly induced forceful vomiting produced by ipecac was considered for many years to be an important front-line treatment for orally ingested poisons. However, subsequent studies (including a comprehensive 2005 meta-study) revealed the stomach purging produced by ipecac to be far less effective at lowering total body poison concentrations than the adsorption effect of oral activated charcoal (which is effective through the entire gastrointestinal tract and is often coupled with whole bowel irrigation). Ipecac also presents a small risk of overdose (being a mild poison itself) and a major risk of esophagitis and aspiration pneumonia if used to p ...
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Jean Claude Adrien Helvetius
Jean may refer to: People * Jean (female given name) * Jean (male given name) * Jean (surname) Fictional characters * Jean Grey, a Marvel Comics character * Jean Valjean, fictional character in novel ''Les Misérables'' and its adaptations * Jean Pierre Polnareff, a fictional character from ''JoJo's Bizarre Adventure'' Places * Jean, Nevada, USA; a town * Jean, Oregon, USA Entertainment * Jean (dog), a female collie in silent films * "Jean" (song) (1969), by Rod McKuen, also recorded by Oliver * ''Jean Seberg'' (musical), a 1983 musical by Marvin Hamlisch Other uses * JEAN (programming language) * USS ''Jean'' (ID-1308), American cargo ship c. 1918 * Sternwheeler Jean, a 1938 paddleboat of the Willamette River See also * Jehan * * Gene (other) * Jeanne (other) * Jehanne (other) * Jeans (other) Jeans are denim trousers. Jeans may also refer to: Astronomy * Jeans (lunar crater) * Jeans (Martian crater) * 2763 Jeans, an asteroi ...
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Tannin
Tannins (or tannoids) are a class of astringent, polyphenolic biomolecules that bind to and precipitate proteins and various other organic compounds including amino acids and alkaloids. The term ''tannin'' (from Anglo-Norman ''tanner'', from Medieval Latin ''tannāre'', from ''tannum'', oak bark) refers to the use of oak and other bark in tanning animal hides into leather. By extension, the term ''tannin'' is widely applied to any large polyphenolic compound containing sufficient hydroxyls and other suitable groups (such as carboxyls) to form strong complexes with various macromolecules. The tannin compounds are widely distributed in many species of plants, where they play a role in protection from predation (acting as pesticides) and might help in regulating plant growth. The astringency from the tannins is what causes the dry and puckery feeling in the mouth following the consumption of unripened fruit, red wine or tea. Likewise, the destruction or modification of t ...
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Cephaeline
Cephaeline is an alkaloid that is found in ''Cephaelis ipecacuanha'' and other plant species including '' Psychotria acuminata''. Cephaeline induces vomiting by stimulating the stomach lining and is found in commercial products such as syrup of ipecac. Chemically, it is closely related to emetine Emetine is a drug used as both an anti-protozoal and to induce vomiting. It is produced from the ipecac root. It takes its name from its emetic properties. Early preparations Mechanism of action of emetine was studied by François Magendie during .... Poison treatment Cephaeline in the form of syrup of ipecac was once commonly recommended as an emergency treatment for accidental poisoning, but its use has been phased out due to its ineffectiveness. References {{Reflist Isoquinoline alkaloids Phenols Norsalsolinol ethers Emetics Drugs with no legal status ...
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Dover's Powder
Dover's powder was a traditional medicine against cold and fever developed by Thomas Dover. It is no longer in use in modern medicine, but may have been in use at least through the 1960s. A 1958 source describes Dover's Powder as follows: "Powder of Ipecacuanha and Opium (''B.P.'', ''Egyp. P.'', ''Ind. P.''). Pulv. Ipecac. et Opii; Ipecac and Opium Powder (''U.S.N.F.''); Dover's Powder; Compound Ipecacuanha Powder. Prepared ipecacuanha, 10 g., powdered opium 10 g., lactose 80 g. It contains 1% of anhydrous morphine. ''Dose:'' 320 to 640 mg. (5 to 10 grains). Many foreign pharmacies include a similar powder, sometimes with potassium sulphate or with equal parts of potassium nitrate and potassium sulphate in place of lactose; ''max. single dose'' 1 to 1.5 g. and max. in 24 hours 4 to 6 g."''The Extra Pharmacopoeia Martindale''. Vol. 1, 24th edition. London: The Pharmaceutical Press, 1958, page 812. This reference also cites "Tablets of Ipecacuanha and Opium (''B.P.'', ''Ind. P ...
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Bronchitis
Bronchitis is inflammation of the bronchi (large and medium-sized airways) in the lungs that causes coughing. Bronchitis usually begins as an infection in the nose, ears, throat, or sinuses. The infection then makes its way down to the bronchi. Symptoms include coughing up sputum, wheezing, shortness of breath, and chest pain. Bronchitis can be acute or chronic. Acute bronchitis usually has a cough that lasts around three weeks, and is also known as a chest cold. In more than 90% of cases the cause is a viral infection. These viruses may be spread through the air when people cough or by direct contact. A small number of cases are caused by a bacterial infection such as ''Mycoplasma pneumoniae'' or ''Bordetella pertussis''. Risk factors include exposure to tobacco smoke, dust, and other air pollution. Treatment of acute bronchitis typically involves rest, paracetamol (acetaminophen), and nonsteroidal anti-inflammatory drugs (NSAIDs) to help with the fever. Chronic bronchi ...
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Diaphoretic
Perspiration, also known as sweating, is the production of fluids secreted by the sweat glands in the skin of mammals. Two types of sweat glands can be found in humans: eccrine glands and apocrine glands. The eccrine sweat glands are distributed over much of the body and are responsible for secreting the watery, brackish sweat most often triggered by excessive body temperature. The apocrine sweat glands are restricted to the armpits and a few other areas of the body and produce an odorless, oily, opaque secretion which then gains its characteristic odor from bacterial decomposition. In humans, sweating is primarily a means of thermoregulation, which is achieved by the water-rich secretion of the eccrine glands. Maximum sweat rates of an adult can be up to 2–4 liters per hour or 10–14 liters per day (10–15 g/min·m2), but is less in children prior to puberty. Evaporation of sweat from the skin surface has a cooling effect due to evaporative cooling. Hence, in hot weath ...
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Expectorant
Mucoactive agents are a class of chemical agents that aid in the clearance of mucus or sputum from the upper and lower airways, including the lungs, bronchi, and trachea. Mucoactive drugs include expectorants, mucolytics, mucoregulators, and mucokinetics. These medications are used in the treatment of respiratory diseases that are complicated by the oversecretion or inspissation of mucus. These drugs can be further categorized by their mechanism of action. Mechanism of action Mucoactive agents - expectorants – include mucolytics, secretolytics and mucokinetics (also called secretomotorics) * Mucolytics – thin (reduce the viscosity of) mucus * Secretolytics – increase airway water or the volume of airway secretions * Mucokinetics – increase mucociliary transport (clearance) and transportability of mucus by cough * Mucoregulators – suppress underlying mechanisms of mucus hypersecretion Alternatively, attacking the affinity between secretions and the biological surfaces ...
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Nauseant
Vomiting (also known as emesis and throwing up) is the involuntary, forceful expulsion of the contents of one's stomach through the mouth and sometimes the nose. Vomiting can be the result of ailments like food poisoning, gastroenteritis, pregnancy, motion sickness, or hangover; or it can be an after effect of diseases such as brain tumors, elevated intracranial pressure, or overexposure to ionizing radiation. The feeling that one is about to vomit is called nausea; it often precedes, but does not always lead to vomiting. Impairment due to alcohol or anesthesia can cause inhalation of vomit, leading to suffocation. In severe cases, where dehydration develops, intravenous fluid may be required. Antiemetics are sometimes necessary to suppress nausea and vomiting. Self-induced vomiting can be a component of an eating disorder such as bulimia, and is itself now classified as an eating disorder on its own, purging disorder. Complications Aspiration Vomiting is dangerou ...
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Poison
Poison is a chemical substance that has a detrimental effect to life. The term is used in a wide range of scientific fields and industries, where it is often specifically defined. It may also be applied colloquially or figuratively, with a broad sense. Whether something is considered a poison may change depending on the amount, the circumstances, and what living things are present. Poisoning could be accidental or deliberate, and if the cause can be identified there may be ways to neutralise the effects or minimise the symptoms. In biology, a poison is a chemical substance causing death, injury or harm to organisms or their parts. In medicine, poisons are a kind of toxin that are delivered passively, not actively. In industry the term may be negative, something to be removed to make a thing safe, or positive, an agent to limit unwanted pests. In ecological terms, poisons introduced into the environment can later cause unwanted effects elsewhere, or in other parts of the food ...
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