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CVM
CVM may refer to: Veterinary medicine * California Variegated Mutant, a sheep breed * Center for Veterinary Medicine of U.S. FDA * Cervical Vertebral Malformation or wobbler disease of dogs and horses * Complex vertebral malformation of Holstein cattle Other uses * Christian Vision for Men, a UK charity * Climate Vulnerability Monitor * Securities Commission (Brazil) * Cooperation and Verification Mechanism The Mechanism for Cooperation and Verification (CVM) is a safeguard measure invoked by the European Commission when a new member or acceding state of the European Union has failed to implement commitments undertaken in the context of the access ... of EU applicant state * General Pedro J. Méndez International Airport in Ciudad Victoria, Mexico, IATA code {{Disambiguation ...
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Complex Vertebral Malformation
Complex vertebral malformation or CVM is a lethal hereditary syndrome found in Holstein cattle. CVM is responsible for malformed calves that are either spontaneously aborted or die shortly after birth. It is caused by a missense mutation in the SLC35A3 gene. Since the mutant form of the gene is recessive, only individuals carrying two copies of the faulty gene (homozygous individuals) are affected. Heterozygous individuals, those who carry one copy of the faulty gene and one copy of the normal gene, have no symptoms but may still pass the disease on to their offspring. Origin CVM has been traced back to the bull Carlin-M Ivanhoe Bell who lived in the 1980s. He was used for two decades in international Holstein breeding for the exceptional milk production he passed on to his daughters. Unusually, Carlin-M Ivanhoe Bell was a carrier for two genetic diseases, CVM and Bovine leukocyte adhesion deficiency (BLAD). The BLAD and CVM genes are located in different chromosomes. When the sir ...
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