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CRON-diet
The CRON-diet (Calorie Restriction with Optimal Nutrition) is a nutrient-rich, reduced calorie diet developed by Roy Walford, Lisa Walford, and Brian M. Delaney. The CRON-diet involves calorie restriction in the hope that the practice will improve health and retard aging, while still attempting to provide the recommended daily amounts of various nutrients. Other names include ''CR-diet'', ''Longevity diet'', and ''Anti-Aging Plan''. The Walfords and Delaney, among others, founded the CR Society International to promote the CRON-diet. Context There is no experimental evidence that calorie restriction can slow biological aging in humans. The biological mechanisms for the supposed antiaging effects are not determined, as of 2021. Origins The CRON-diet was developed from data Walford compiled during his participation in Biosphere 2 from 1991 to 1993. The subjects ate a diet low in fat and in calories but "nutrient-dense", derived from the food crops raised inside the Biospher ...
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CR Society International
The CR Society International (or CRSI) is a nonprofit 501(c)(3) organization that was previously known as the CR Society or Calorie Restriction Society. In 1994, Brian M. Delaney, Lisa Walford, and Roy Walford, along with several others, founded CR Society International. The group sponsors conferences and funds anti-aging research. See also * CRON-diet Further reading * Conniff, Richard (February 16, 2017)"The Hunger Gains: Extreme Calorie-Restriction Diet Shows Anti-Aging Results"* Lauth, Kimberly (October 21, 2009)"Calorie restriction: fountain of youth or dangerous diet?"Should you severely restrict calories? CNN Interview with Brian M. Delaney* Seligman, Katherine (September 2, 2007) ''San Francisco Chronicle The ''San Francisco Chronicle'' is a newspaper serving primarily the San Francisco Bay Area of Northern California. It was founded in 1865 as ''The Daily Dramatic Chronicle'' by teenage brothers Charles de Young and M. H. de Young, Michael H. de ...''"Iron Will: C ...
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Roy Walford
Roy Lee Walford, M. D. (June 29, 1924 – April 27, 2004) was a professor of pathology at University of California, Los Angeles School of Medicine, a leading advocate of calorie restriction for life extension and health improvement, and a crew member of Biosphere 2. Career highlights Walford is credited with significantly furthering aging research by his discovery that laboratory mice, when fed a diet that restricted their caloric intake by 50% yet maintaining nutritional requirements, almost doubled their expected life span. He received his medical degree from the University of Chicago in 1948. He completed his internship at Gorgas Hospital, Panama, and served his residency at the V.A. Medical Center in Los Angeles. He then served two years in the US Air Force during the Korean War. Walford joined the faculty at the University of California at Los Angeles (UCLA) in 1954. He became a Professor of Pathology at the UCLA School of Medicine in 1966. He became Professor of Patholog ...
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Christopher Turner
Christopher Turner is a British writer. He has been a regular contributor to ''Cabinet'' magazine since 2004, and to the ''London Review of Books'' since 2001. He has also written for ''The Guardian'' and ''The Sunday Telegraph'', and is the editor of ''Icon'' magazine. Turner is the author of ''Adventures in the Orgasmatron: Wilhelm Reich and the Invention of Sex'' (2011), which was long-listed for the Orwell Prize The Orwell Prize, based at University College London, is a British prize for political writing. The Prize is awarded by The Orwell Foundation, an independent charity (Registered Charity No 1161563, formerly "The Orwell Prize") governed by a boa .... Background Turner obtained an MA in anthropology, archaeology and art history from the University of Cambridge, and his PhD in 2000 in humanities and cultural studies from the London Consortium, with a thesis entitled "The Disgusting: The Unrepresentable from Kant to Kristeva." He was a visiting scholar at Columbia U ...
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Diets
The Low Countries comprise the coastal Rhine–Meuse–Scheldt delta region in Western Europe, whose definition usually includes the modern countries of Luxembourg, Belgium and the Netherlands. Both Belgium and the Netherlands derived their names from earlier names for the region, due to ''nether'' meaning "low" and ''Belgica'' being the Latinized name for all the Low Countries, a nomenclature that became obsolete after Belgium's secession in 1830. The Low Countries—and the Netherlands and Belgium—had in their history exceptionally many and widely varying names, resulting in equally varying names in different languages. There is diversity even within languages: the use of one word for the country and another for the adjective form is common. This holds for English, where ''Dutch'' is the adjective form for the country "the Netherlands". Moreover, many languages have the same word for both the country of the Netherlands and the region of the Low Countries, e.g., French ( ...
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Bulgur
Bulgur (from tr, bulgur, itself from fa, بلغور, bolġur (bolghur)/balġur (balghur), groats ), also riffoth (from biblical he, ריפות, riffoth) and burghul (from ar, برغل, burġul ), is a cracked wheat dish found in West Asian cuisine. Characteristics Bulgur is sometimes confused with cracked wheat, which is crushed wheat grain that, unlike bulgur, has not been parboiled. Bulgur is a common ingredient in cuisines of many countries of the West Asian cuisine and Mediterranean Basin. It has a light, nutty flavor. Bulgur is recognized as a whole grain by the United States Department of Agriculture. Composition and nutrition Cooked bulgur is 78% water, 19% carbohydrates, 3% protein, and contains negligible fat (table). A 100 gram (3.5 oz) reference serving supplies 83 calories, with no micronutrients in appreciable amounts of the Daily Value (table). Culinary uses Bulgur does not require cooking, although it can be included in cooked dishe ...
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Slate (magazine)
''Slate'' is an online magazine that covers current affairs, politics, and culture in the United States. It was created in 1996 by former '' New Republic'' editor Michael Kinsley, initially under the ownership of Microsoft as part of MSN. In 2004, it was purchased by The Washington Post Company (later renamed the Graham Holdings Company), and since 2008 has been managed by The Slate Group, an online publishing entity created by Graham Holdings. ''Slate'' is based in New York City, with an additional office in Washington, D.C. ''Slate'', which is updated throughout the day, covers politics, arts and culture, sports, and news. According to its former editor-in-chief Julia Turner, the magazine is "not fundamentally a breaking news source", but rather aimed at helping readers to "analyze and understand and interpret the world" with witty and entertaining writing. As of mid-2015, it publishes about 1,500 stories per month. A French version, ''slate.fr'', was launched in February 20 ...
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Emily Yoffe
Emily J. Yoffe (born October 15, 1955) is an American journalist and contributing writer for ''The Atlantic''. From 1998 to 2016 she was a regular contributor to ''Slate'' magazine, notably as Dear Prudence. She has also written for ''The New York Times; O, The Oprah Magazine; The Washington Post;'' ''Esquire''; the ''Los Angeles Times''; ''Texas Monthly''; and many other publications. Yoffe began her career as a staff writer at ''The New Republic'' before moving on to other publications. Career In 2006 outgoing columnist Margo Howard turned ''Slate''s "Dear Prudence" advice column over to Yoffe. The column appears four times per week, including one day of live chats and one day in which the letters are responded to using a video instead of text. In November 2015, Yoffe published her last "Dear Prudence" column, and was replaced by Daniel M. Lavery, co-founder of ''The Toast''. Lavery left Dear Prudence in 2021. Yoffe also hosted a podcast called "Manners for the Digital Ag ...
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Lou Gehrig Disease
Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND) or Lou Gehrig's disease, is a neurodegenerative disease that results in the progressive loss of motor neurons that control voluntary muscles. ALS is the most common type of motor neuron diseases. Early symptoms of ALS include stiff muscles, muscle twitches, and gradual increasing weakness and muscle wasting. ''Limb-onset ALS'' begins with weakness in the arms or legs, while ''bulbar-onset ALS'' begins with difficulty speaking or swallowing. Half of the people with ALS develop at least mild difficulties with thinking and behavior, and about 15% develop frontotemporal dementia. Most people experience pain. The affected muscles are responsible for chewing food, speaking, and walking. Motor neuron loss continues until the ability to eat, speak, move, and finally the ability to breathe is lost. ALS eventually causes paralysis and early death, usually from respiratory failure. Most cases of ALS (about ...
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Pagan Kennedy
Pagan Kennedy (born c. 1963) is an American columnist and author, and pioneer of the 1990s zine movement. She has written ten books in a variety of genres, was a regular contributor to the ''Boston Globe'', and has published articles in dozens of magazines and newspapers. In 2012–13, she was a ''New York Times Magazine'' columnist. Early life and education Born Pamela Kennedy around 1963, she grew up in suburban Washington, D.C. She graduated from Wesleyan University in 1984, and later spent a year in the Masters of Fine Arts program at Johns Hopkins University. Career Kennedy's autobiographical zine ''Pagan's Head'' detailed her life during her twenties. Kennedy wrote a biography called ''The First Man-Made Man'' about Michael Dillon who in the 1940s was the first successful case of female-to-male sex change treatment; he established himself as a medical student. It describes how he later fell in love with a male-to-female transsexual, Roberta Cowell, who was at the time t ...
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Clinical Trials
Clinical trials are prospective biomedical or behavioral research studies on human participants designed to answer specific questions about biomedical or behavioral interventions, including new treatments (such as novel vaccines, drugs, dietary choices, dietary supplements, and medical devices) and known interventions that warrant further study and comparison. Clinical trials generate data on dosage, safety and efficacy. They are conducted only after they have received health authority/ethics committee approval in the country where approval of the therapy is sought. These authorities are responsible for vetting the risk/benefit ratio of the trial—their approval does not mean the therapy is 'safe' or effective, only that the trial may be conducted. Depending on product type and development stage, investigators initially enroll volunteers or patients into small pilot studies, and subsequently conduct progressively larger scale comparative studies. Clinical trials can vary i ...
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The New York Times
''The New York Times'' (''the Times'', ''NYT'', or the Gray Lady) is a daily newspaper based in New York City with a worldwide readership reported in 2020 to comprise a declining 840,000 paid print subscribers, and a growing 6 million paid digital subscribers. It also is a producer of popular podcasts such as '' The Daily''. Founded in 1851 by Henry Jarvis Raymond and George Jones, it was initially published by Raymond, Jones & Company. The ''Times'' has won 132 Pulitzer Prizes, the most of any newspaper, and has long been regarded as a national " newspaper of record". For print it is ranked 18th in the world by circulation and 3rd in the U.S. The paper is owned by the New York Times Company, which is publicly traded. It has been governed by the Sulzberger family since 1896, through a dual-class share structure after its shares became publicly traded. A. G. Sulzberger, the paper's publisher and the company's chairman, is the fifth generation of the family to head the pa ...
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Brian M
Brian (sometimes spelled Bryan in English) is a male given name of Irish and Breton origin, as well as a surname of Occitan origin. It is common in the English-speaking world. It is possible that the name is derived from an Old Celtic word meaning "high" or "noble". For example, the element ''bre'' means "hill"; which could be transferred to mean "eminence" or "exalted one". The name is quite popular in Ireland, on account of Brian Boru, a 10th-century High King of Ireland. The name was also quite popular in East Anglia during the Middle Ages. This is because the name was introduced to England by Bretons following the Norman Conquest. Bretons also settled in Ireland along with the Normans in the 12th century, and 'their' name was mingled with the 'Irish' version. Also, in the north-west of England, the 'Irish' name was introduced by Scandinavian settlers from Ireland. Within the Gaelic speaking areas of Scotland, the name was at first only used by professional families of Irish ...
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