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COVID-19 Pandemic In Toronto
The COVID-19 pandemic in Toronto is an ongoing viral pandemic of coronavirus disease 2019 (COVID-19), a novel infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Toronto is the most populous city in Canada, and the fourth most populous city in North America. On January 23, 2020, the first identified case of COVID-19 in Canada during the pandemic was admitted to Sunnybrook Health Sciences Centre in Toronto. On March 17, 2020, the government of Ontario declared its first state of emergency during the pandemic, followed by Toronto mayor John Tory declaring a local state of emergency March 23, 2020. Initial restrictions preventing essential businesses from operating (such as the closure of indoor dining and personal care services) continued through until June 24, 2020, when the government of Ontario allowed Toronto to enter Stage 2 of reopening. Toronto introduced mask requirements at all public indoor settings on July 7, 2020. On July 31, ...
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Sunnybrook Health Sciences Centre
Sunnybrook Health Sciences Centre (SHSC), commonly known as Sunnybrook Hospital or simply Sunnybrook, is an academic health science centre An academic medical centre (AMC), variously also known as academic health science centre, academic health science system, or academic health science partnership, is an educational and healthcare institute formed by the grouping of a health profess ... located in Toronto, Ontario, Canada. It is the largest trauma centre in Canada and one of two trauma centres in Toronto, the other being St. Michael's Hospital (Toronto), St. Michael's Hospital. Sunnybrook is a teaching hospital fully affiliated with the University of Toronto. The hospital is home to Canada's largest veterans centre, in the Kilgour Wing and the George Hees, which cares for World War II and Korean War veterans. Sunnybrook has made surgical breakthroughs in its history, including the world's first non-invasive opening of the blood–brain barrier being performed in 2015. History ...
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Variants Of SARS-CoV-2
There are many variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the virus that causes coronavirus disease 2019 (COVID-19). Some are believed, or have been stated, to be of particular importance due to their potential for increased transmissibility, increased virulence, or reduced effectiveness of vaccines against them. These variants contribute to the continuation of the COVID-19 pandemic. only the Omicron variant is designated as a circulating variant of concern by the World Health Organization. Overview The emergence of SARS-CoV-2 may have resulted from recombination events between a bat SARS-like coronavirus and a pangolin coronavirus through cross-species transmission. The earliest available SARS-CoV-2 viral genomes were collected from patients in December 2019, and Chinese researchers compared these early genomes with bat and pangolin coronavirus strains to estimate the ancestral human coronavirus type; the identified ancestral genome type ...
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The Globe And Mail
''The Globe and Mail'' is a Canadian newspaper printed in five cities in western and central Canada. With a weekly readership of approximately 2 million in 2015, it is Canada's most widely read newspaper on weekdays and Saturdays, although it falls slightly behind the ''Toronto Star'' in overall weekly circulation because the ''Star'' publishes a Sunday edition, whereas the ''Globe'' does not. ''The Globe and Mail'' is regarded by some as Canada's " newspaper of record". ''The Globe and Mail''s predecessors, '' The Globe'' and ''The Mail and Empire'' were both established in the 19th century. The former was established in 1844, while the latter was established in 1895 through a merger of ''The Toronto Mail'' and the ''Toronto Empire''. In 1936, ''The Globe'' and ''The Mail and Empire'' merged to form ''The Globe and Mail''. The newspaper was acquired by FP Publications in 1965, who later sold the paper to the Thomson Corporation in 1980. In 2001, the paper merged with broadcast ...
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Manitoba
Manitoba ( ) is a Provinces and territories of Canada, province of Canada at the Centre of Canada, longitudinal centre of the country. It is Canada's Population of Canada by province and territory, fifth-most populous province, with a population of 1,342,153 as of 2021, of widely varied landscape, from arctic tundra and the Hudson Bay coastline in the Northern Region, Manitoba, north to dense Boreal forest of Canada, boreal forest, large freshwater List of lakes of Manitoba, lakes, and prairie grassland in the central and Southern Manitoba, southern regions. Indigenous peoples in Canada, Indigenous peoples have inhabited what is now Manitoba for thousands of years. In the early 17th century, British and French North American fur trade, fur traders began arriving in the area and establishing settlements. The Kingdom of England secured control of the region in 1673 and created a territory named Rupert's Land, which was placed under the administration of the Hudson's Bay Company. Rupe ...
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Winnipeg
Winnipeg () is the capital and largest city of the province of Manitoba in Canada. It is centred on the confluence of the Red and Assiniboine rivers, near the longitudinal centre of North America. , Winnipeg had a city population of 749,607 and a metropolitan population of 834,678, making it the sixth-largest city, and eighth-largest metropolitan area in Canada. The city is named after the nearby Lake Winnipeg; the name comes from the Western Cree words for "muddy water" - “winipīhk”. The region was a trading centre for Indigenous peoples long before the arrival of Europeans; it is the traditional territory of the Anishinabe (Ojibway), Ininew (Cree), Oji-Cree, Dene, and Dakota, and is the birthplace of the Métis Nation. French traders built the first fort on the site in 1738. A settlement was later founded by the Selkirk settlers of the Red River Colony in 1812, the nucleus of which was incorporated as the City of Winnipeg in 1873. Being far inland, the local cl ...
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National Microbiology Laboratory
The National Microbiology Laboratory (NML) is part of the Public Health Agency of Canada (PHAC), the agency of the Government of Canada that is responsible for public health, health emergency preparedness and response, and infectious and chronic disease control and prevention. NML is located in several sites across the country including the Canadian Science Centre for Human and Animal Health (CSCHAH) in Winnipeg, Manitoba. NML has a second site in Winnipeg, the Wilt Infectious Disease Research Centre on Logan Avenue which serves as a hub for HIV research and diagnostics in Canada. The three other primary sites include locations in Guelph, St. Hyacinthe and Lethbridge. The CSCHAH is a biosafety level 4 infectious disease laboratory facility, the only one of its kind in Canada. With maximum containment, scientists are able to work with pathogens including Ebola, Marburg and Lassa fever. The NML's CSCHAH is also home to the Canadian Food Inspection Agency's National Centre for Fo ...
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Public Health Ontario
The Ontario Agency for Health Protection and Promotion (more commonly known as Public Health Ontario) is the Ontario Government agency responsible for providing scientific and technical advice to those working to promote and protect the health of people in Ontario, Canada. History and organization The Ontario Agency for Health Protection and Promotion was established in 2008 by the Ontario Agency for Health Protection and Promotion Act, 2007. The OAHPP is an agent of the Crown (i.e. a Crown agency) and is considered an arm's-length government agency. It has a mandate to provide scientific and technical advice to those working to protect and promote the health of Ontario residents. Its objectives include establishing, operating and maintaining laboratory centers, providing laboratory services, and operating Ontario public health laboratories previously operated by the Ministry of Health and Long-Term Care. As of December 15, 2008, the Ministry of Health and Long-Term Care annou ...
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Guangzhou
Guangzhou (, ; ; or ; ), also known as Canton () and alternatively romanized as Kwongchow or Kwangchow, is the capital and largest city of Guangdong province in southern China. Located on the Pearl River about north-northwest of Hong Kong and north of Macau, Guangzhou has a history of over 2,200 years and was a major terminus of the maritime Silk Road; it continues to serve as a major port and transportation hub as well as being one of China's three largest cities. For a long time, the only Chinese port accessible to most foreign traders, Guangzhou was captured by the British during the First Opium War. No longer enjoying a monopoly after the war, it lost trade to other ports such as Hong Kong and Shanghai, but continued to serve as a major transshipment port. Due to a high urban population and large volumes of port traffic, Guangzhou is classified as a Large-Port Megacity, the largest type of port-city in the world. Due to worldwide travel restrictions at the beginni ...
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Janssen COVID-19 Vaccine
The Janssen COVID19 vaccine, sold under the brand name Jcovden, is a COVID19 vaccine that was developed by Janssen Vaccines in Leiden, Netherlands, and its Belgian parent company Janssen Pharmaceuticals, a subsidiary of American company Johnson & Johnson. It is a viral vector vaccine based on a human adenovirus that has been modified to contain the gene for making the spike protein of the SARS-CoV-2 virus that causes COVID19. The body's immune system responds to this spike protein to produce antibodies. The vaccine requires only one dose and does not need to be stored frozen. Clinical trials for the vaccine were started in June 2020, with phaseIII involving around 43,000 people. On 29 January 2021, Janssen announced that 28 days after a completed vaccination, the vaccine was 66% effective in a one-dose regimen in preventing symptomatic COVID19, with an 85% efficacy in preventing severe COVID19 and 100% efficacy in preventing hospitalization or death caused by the disease ...
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Oxford–AstraZeneca COVID-19 Vaccine
The Oxford–AstraZeneca COVID19 vaccine, sold under the brand names Covishield and Vaxzevria among others, is a viral vector vaccine for prevention of COVID-19. Developed in the United Kingdom by Oxford University and British-Swedish company AstraZeneca, using as a vector the modified chimpanzee adenovirus ChAdOx1. The vaccine is given by intramuscular injection. Studies carried out in 2020 showed that the efficacy of the vaccine is 76.0% at preventing symptomatic COVID-19 beginning at 22 days following the first dose, and 81.3% after the second dose. A study in Scotland found that, for symptomatic COVID-19 infection after the second dose, the vaccine is 81% effective against the Alpha variant (lineage B.1.1.7), and 61% against the Delta variant (lineage B.1.617.2). The vaccine is stable at refrigerator temperatures and has a good safety profile, with side effects including injection-site pain, headache, and nausea, all generally resolving within a few days. More rarely, ...
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COVID-19 Vaccination In Canada
COVID-19 vaccination in Canada is an ongoing, intergovernmental effort coordinated between the bodies responsible in the Government of Canada to acquire and distribute vaccines to individual provincial and territorial governments who in turn administer authorized COVID-19 vaccines during the COVID-19 pandemic in Canada. Provinces have worked with local municipal governments, hospital systems, family doctors and independently owned pharmacies to aid in part, or in full with vaccination rollout. The vaccination effort in full is the largest such immunization effort in the nation's history. The vaccination effort began December 14, 2020, and is currently ongoing. Health Canada is responsible for approval and regulation of vaccines (and other pharmaceuticals), while the Public Health Agency of Canada (PHAC) is responsible for public health, emergency preparedness and response, and infectious and chronic disease control and prevention. Vaccines are authorized by Health Canada, ...
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Moderna
Moderna, Inc. ( ) is an American pharmaceutical and biotechnology company based in Cambridge, Massachusetts that focuses on RNA therapeutics, primarily mRNA vaccines. These vaccines use a copy of a molecule called messenger RNA (mRNA) to produce an immune response. The company's only commercial product is the Moderna COVID-19 vaccine, marketed as Spikevax. As of 2022, the company has 44 treatment and vaccine candidates, of which 21 have entered clinical trials. Targets for vaccine candidates include influenza, HIV, respiratory syncytial virus, Epstein–Barr virus, the Nipah virus, chikungunya, a combined single-shot COVID-19 booster and influenza vaccine, a cytomegalovirus vaccine, and two cancer vaccines. The company's pipeline also includes candidates for cancer immunotherapy using OX40 ligand, interleukin 23, IL36G, and interleukin 12 as well as, in partnership with AstraZeneca, a regenerative medicine treatment that encodes vascular endothelial growth factor A to stimul ...
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