COPS2
COP9 signalosome complex subunit 2 is a protein that in humans is encoded by the ''COPS2'' gene. It encodes a subunit of the COP9 signalosome. Interactions COPS2 has been shown to interact with: * DAX1, * IRF8 Interferon regulatory factor 8 (IRF8) also known as interferon consensus sequence-binding protein (ICSBP), is a protein that in humans is encoded by the ''IRF8'' gene. IRF8 is a transcription factor that plays critical roles in the regulation of ..., * NIF3L1, and * THRA. References External links * * Further reading * * * * * * * * * * * * * * * * * {{gene-15-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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NIF3L1
NIF3-like protein 1 is a protein that in humans is encoded by the ''NIF3L1'' gene. Interactions NIF3L1 has been shown to interact with COPS2 COP9 signalosome complex subunit 2 is a protein that in humans is encoded by the ''COPS2'' gene. It encodes a subunit of the COP9 signalosome. Interactions COPS2 has been shown to interact with: * DAX1, * IRF8 Interferon regulatory facto .... References Further reading * * * * * * {{gene-2-stub ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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IRF8
Interferon regulatory factor 8 (IRF8) also known as interferon consensus sequence-binding protein (ICSBP), is a protein that in humans is encoded by the ''IRF8'' gene. IRF8 is a transcription factor that plays critical roles in the regulation of lineage commitment and in myeloid cell maturation including the decision for a common myeloid progenitor (CMP) to differentiate into a monocyte precursor cell. Function Interferon Consensus Sequence-binding protein (ICSBP) is a transcription factor of the interferon regulatory factor ( IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-α and IFN-β. IRF family proteins also control expression of IFN-α and IFN-β-regulated genes that are induced by viral infection. ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Protein
Proteins are large biomolecules and macromolecules that comprise one or more long chains of amino acid residue (biochemistry), residues. Proteins perform a vast array of functions within organisms, including Enzyme catalysis, catalysing metabolic reactions, DNA replication, Cell signaling, responding to stimuli, providing Cytoskeleton, structure to cells and Fibrous protein, organisms, and Intracellular transport, transporting molecules from one location to another. Proteins differ from one another primarily in their sequence of amino acids, which is dictated by the Nucleic acid sequence, nucleotide sequence of their genes, and which usually results in protein folding into a specific Protein structure, 3D structure that determines its activity. A linear chain of amino acid residues is called a polypeptide. A protein contains at least one long polypeptide. Short polypeptides, containing less than 20–30 residues, are rarely considered to be proteins and are commonly called pep ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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Gene
In biology, the word gene has two meanings. The Mendelian gene is a basic unit of heredity. The molecular gene is a sequence of nucleotides in DNA that is transcribed to produce a functional RNA. There are two types of molecular genes: protein-coding genes and non-coding genes. During gene expression (the synthesis of Gene product, RNA or protein from a gene), DNA is first transcription (biology), copied into RNA. RNA can be non-coding RNA, directly functional or be the intermediate protein biosynthesis, template for the synthesis of a protein. The transmission of genes to an organism's offspring, is the basis of the inheritance of phenotypic traits from one generation to the next. These genes make up different DNA sequences, together called a genotype, that is specific to every given individual, within the gene pool of the population (biology), population of a given species. The genotype, along with environmental and developmental factors, ultimately determines the phenotype ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |
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COP9 Signalosome
The 2003 United Nations Climate Change Conference took place between 1–12 December 2003 in Milan, Italy. The conference included the 9th Conference of the Parties (COP9) to the United Nations Framework Convention on Climate Change (UNFCCC). The parties agreed to use the Adaptation Fund established at COP7 in 2001 primarily in supporting developing countries better adapt to climate change. The fund would also be used for capacity-building through technology transfer. At the conference, the parties also agreed to review the first national reports submitted by 110 non-Annex I countries. References 21st-century diplomatic conferences Diplomatic conferences in Italy 2003 2003 2003 was designated by the United Nations as the International Year of Fresh water, Freshwater. In 2003, a Multi-National Force – Iraq, United States-led coalition 2003 invasion of Iraq, invaded Iraq, starting the Iraq War. Demographic ... 2003 in international relations 2003 in the env ... [...More Info...]       [...Related Items...]     OR:     [Wikipedia]   [Google]   [Baidu]   |