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CHRS2
The Centre for Human Reproductive Science (ChRS) was established in December 2006 to further develop research and innovation in fertility diagnosis and treatment, working in partnership as the academic and research wing of the Birmingham Women's Fertility Centre at Birmingham Women’s Hospital and the University of Birmingham Medical School. A particular emphasis in the biomedical research strategy is placing research and discovery in the true physiological context. Current Research and Funding The current focus and funding of the Centre includes: * Translational medicine research funded by the National Institute for Health and Care Research (NIHR) on Andrology and male factors in healthy live birth * Research into the role for paternal sperm DNA damage in unexplained miscarriage, its diagnosis and treatment - as part of the Tommy's National Centre for Miscarriage Research * Research into advanced computer-assisted diagnosis of male fertility issues - funded by the EPSRC * A ...
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Birmingham Women's Fertility Centre
The Birmingham Women's Fertility Centre at Birmingham Women’s Hospital, Birmingham, England, formerly named the "Assisted Conception Unit", is one of the UK's leading medical centres for infertility treatment and care. It is the longest established fertility clinic in the Midlands, marking thirty years operations in the year 2010. The clinic is based in an NHS hospital and provides integrated care to both NHS and private patients; the staff is internationally recognised for their work in treating with infertility. The clinic runs active programmes of egg-sharing, sperm donation and egg-donation. Care Advances The Fertility Centre was one of five clinics selected around the UK to receive Medical Research Council funding to elevate the IVF laboratories to ‘cleanroom’ levels. This is fundamental for producing human embryonic stem cells that are suitable for human use, as all stages of development were in strictly controlled conditions. These opened in summer 2006 and the ce ...
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Birmingham Women’s Hospital
Birmingham Women's and Children's NHS Foundation Trust ran Birmingham Women's Hospital in the Edgbaston area of Birmingham, situated very close to the University of Birmingham. On 1 February 2008, it was granted NHS Foundation Trust Status. It merged into Birmingham Women's and Children's NHS Foundation Trust in 2017 Services The first Birmingham maternity hospital was established in 1842 to reduce the number of women and children dying needlessly from puerperal fever and childbirth related infections. This hospital has been at its present site since 1994, and is one of only two trusts in the UK specialising in women's health care. They provide a focused range of health care services, primarily, though not exclusively, to women and their families. These are: *Maternity and foetal medicine services *Neonatal care and newborn transport service *Milk bank—the only one in the West Midlands. It provides donor breast milk for its own neonatal babies and also distributes donor breas ...
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University Of Birmingham Medical School
The University of Birmingham Medical School is one of Britain's largest and oldest medical schools with over 400 medical, 70 pharmacy, 140 biomedical science and 130 nursing students graduating each year. It is based at the University of Birmingham in Edgbaston, Birmingham, United Kingdom. Since 2008, the medical school is a constituent of The College of Medical and Dental Sciences. History The roots of the Birmingham Medical School were in the medical education seminars of Mr. John Tomlinson, first surgeon to the Birmingham Workhouse Infirmary and later to the General Hospital. These classes were the first held in the winter of 1767–68. The first clinical teaching was undertaken by medical and surgical apprentices at the General Hospital, opened in 1779. Birmingham Medical School was founded in 1825 by William Sands Cox, who began by teaching medical students in his father's house in Birmingham. A new building was used from 1829 (on the site of what is now Snow Hill ...
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National Institute For Health And Care Research
The National Institute for Health and Care Research (NIHR) is the British government’s major funder of clinical, public health, social care and translational research. With a budget of over £1.2 billion in 2020–21, its mission is to "improve the health and wealth of the nation through research". The NIHR was established in 2006 under the government's Best Research for Best Health strategy, and is funded by the Department of Health and Social Care. As a research funder and research partner of the NHS, public health and social care, the NIHR complements the work of the Medical Research Council. NIHR focuses on translational research (translating discoveries from the laboratory to the clinic), clinical research and applied health and social care research. History The NIHR (originally named National Institute for Health Research) was created in April 2006 under the government's health research strategy, Best Research for Best Health. This strategy outlined the direction that ...
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Andrology
Andrology (from grc, ἀνήρ, ''anēr'', genitive , ''andros'', "man"; and , ''-logia'') is a name for the medical specialty that deals with male health, particularly relating to the problems of the male reproductive system and urological problems that are unique to men. It is the counterpart to gynaecology, which deals with medical issues which are specific to female health, especially reproductive and urologic health. Process Andrology covers anomalies in the connective tissues pertaining to the genitalia, as well as changes in the volume of cells, such as in genital hypertrophy or macrogenitosomia. From reproductive and urologic viewpoints, male-specific medical and surgical procedures include vasectomy, vasovasostomy (one of the vasectomy reversal procedures), orchidopexy and circumcision as well as intervention to deal with male genitourinary disorders such as the following: History Unlike gynaecology, which has a plethora of medical board certification programs worldw ...
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Engineering And Physical Sciences Research Council
The Engineering and Physical Sciences Research Council (EPSRC) is a British Research Council that provides government funding for grants to undertake research and postgraduate degrees in engineering and the physical sciences, mainly to universities in the United Kingdom. EPSRC research areas include mathematics, physics, chemistry, artificial intelligence and computer science, but exclude particle physics, nuclear physics, space science and astronomy (which fall under the remit of the Science and Technology Facilities Council). Since 2018 it has been part of UK Research and Innovation, which is funded through the Department for Business, Energy and Industrial Strategy. History EPSRC was created in 1994. At first part of the Science and Engineering Research Council (SERC), in 2018 it was one of nine organisations brought together to form UK Research and Innovation (UKRI). Its head office is in Swindon, Wiltshire in the same building (Polaris House) that houses the AHRC, BBSRC ...
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Intracytoplasmic Sperm Injection
Intracytoplasmic sperm injection (ICSI ) is an in vitro fertilization (IVF) procedure in which a single sperm cell is injected directly into the cytoplasm of an egg. This technique is used in order to prepare the gametes for the obtention of embryos that may be transferred to a maternal uterus. With this method, the acrosome reaction is skipped. There are several differences between classic IVF and ICSI. However, the steps to be followed before and after insemination are the same. In terms of insemination, ICSI needs only one sperm cell per oocyte, while IVF needs 50,000–100,000. This is because the acrosome reaction has to take place and thousands of sperm cells have to be involved in IVF. Once fertilized, the egg is transformed into a pre-embryo and it has to be transferred to the uterus to continue its development. The first human pregnancy generated by ICSI was carried out in 1991 by Gianpiero Palermo and his team. Round spermatid injection (ROSI) Round spermatid inject ...
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University Of Birmingham
, mottoeng = Through efforts to heights , established = 1825 – Birmingham School of Medicine and Surgery1836 – Birmingham Royal School of Medicine and Surgery1843 – Queen's College1875 – Mason Science College1898 – Mason University College1900 – gained university status by royal charter , city = Birmingham , province = West Midlands , country = England, UK , coor = , campus = Urban, suburban , academic_staff = 5,495 (2020) , administrative_staff = , head_label = Visitor , head = The Rt Hon Penny Mordaunt MP , chancellor = Lord Bilimoria , vice_chancellor = Adam Tickell , type = Public , endowment = £134.5 million (2021) , budget = £774.1 million (2020–21) , students = () , undergrad = () , postgrad = () , affiliations = Universitas 21Universities UK EUA ACUSutton 13Russell Group , free_label = , free = , colours = The University , website = , logo = The University of Birmingham (informally Birmingham University) i ...
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Medical Research Council (UK)
The Medical Research Council (MRC) is responsible for co-coordinating and funding medical research in the United Kingdom. It is part of United Kingdom Research and Innovation (UKRI), which came into operation 1 April 2018, and brings together the UK's seven research councils, Innovate UK and Research England. UK Research and Innovation is answerable to, although politically independent from, the Department for Business, Energy and Industrial Strategy. The MRC focuses on high-impact research and has provided the financial support and scientific expertise behind a number of medical breakthroughs, including the development of penicillin and the discovery of the structure of DNA. Research funded by the MRC has produced 32 Nobel Prize winners to date. History The MRC was founded as the Medical Research Committee and Advisory Council in 1913, with its prime role being the distribution of medical research funds under the terms of the National Insurance Act 1911. This was a consequen ...
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Cleanroom
A cleanroom or clean room is an engineered space, which maintains a very low concentration of airborne particulates. It is well isolated, well-controlled from contamination, and actively cleansed. Such rooms are commonly needed for scientific research, and in industrial production for all nanoscale processes, such as semiconductor manufacturing. A cleanroom is designed to keep everything from dust, to airborne organisms, or vaporised particles, away from it, and so from whatever material is being handled inside it. The other way around, a cleanroom can also help keep materials escaping from it. This is often the primary aim in hazardous biology and nuclear work, in pharmaceutics and in virology. Cleanrooms typically come with a cleanliness level quantified by the number of particles per cubic meter at a predetermined molecule measure. The ambient outdoor air in a typical urban area contains 35,000,000 particles for each cubic meter in the size range 0.5 μm and bigger, equ ...
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Human Embryonic Stem Cells
Embryonic stem cells (ESCs) are pluripotent stem cells derived from the inner cell mass of a blastocyst, an early-stage pre- implantation embryo. Human embryos reach the blastocyst stage 4–5 days post fertilization, at which time they consist of 50–150 cells. Isolating the inner cell mass (embryoblast) using immunosurgery results in destruction of the blastocyst, a process which raises ethical issues, including whether or not embryos at the pre-implantation stage have the same moral considerations as embryos in the post-implantation stage of development. Researchers are currently focusing heavily on the therapeutic potential of embryonic stem cells, with clinical use being the goal for many laboratories. Potential uses include the treatment of diabetes and heart disease. The cells are being studied to be used as clinical therapies, models of genetic disorders, and cellular/DNA repair. However, adverse effects in the research and clinical processes such as tumors and unwante ...
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HFEA
The Human Fertilisation and Embryology Authority (HFEA) is an executive non-departmental public body of the Department of Health and Social Care in the United Kingdom. It is a statutory body that regulates and inspects all clinics in the United Kingdom providing ''in vitro'' fertilisation (IVF), artificial insemination and the storage of human eggs, sperm or embryos. It also regulates human embryo research. Background to the establishment of the HFEA After the birth of Louise Brown, the world's first IVF baby, in 1978, there was concern about the implications of this new technology. In 1982, the UK government formed a committee chaired by philosopher Mary Warnock to look into the issues and see what action needed to be taken. Hundreds of interested individuals including doctors, scientists and organisations such as health, patient and parent organisations as well as religious groups gave evidence to the committee. In the years following the Warnock report, proposals wer ...
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