CDK2-Selective Inhibitor
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CDK2-Selective Inhibitor
CDK may refer to: * CDK Global, a US-based automotive dealer services company * The IATA airport code for George T. Lewis Airport, Cedar Key, Florida, United States. * Chemistry Development Kit, an open source chemical expert system for chemoinformatics and bioinformatics, written in Java * Chung Do Kwan, founded in 1944, the first of nine schools teaching what came to be known as Taekwondo * Complete knock down, a production technique, often used in automotive industry * Curses Development Kit, one of two open source distributions of the Curses widgets library * Cyclin-dependent kinase, a major class of enzymes involved in the regulation of the cell cycle * Chronic kidney disease, a progressive loss of function of the kidney. * Charles De Ketelaere Charles Marc S. De Ketelaere (born 10 March 2001) is a Belgian professional footballer who plays as an attacking midfielder for club AC Milan and the Belgium national team. Club career Club Brugge De Ketelaere joined Club Br ...
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CDK Global
CDK Global Inc. is an American multinational corporation based in Hoffman Estates, Illinois, providing data and technology to the automotive, heavy truck, recreation, and heavy equipment industries. The company has 37 locations in 25 countries and its products are sold in over 100 countries, however most of its customers are in the United States. In 2020, the company ranked 911 on the Fortune 1000 list of the largest United States corporations by total revenue. Products CDK Global provides integrated information technology and digital marketing to the automotive, heavy truck, recreation, and heavy equipment industries. The company's products help to integrate clients buying processes and include targeted advertising and marketing, as well as products for the sale, financing, insuring, parts supply, repair, and maintenance of vehicles. Competitors include Reynolds and Reynolds and Dealertrack. History The company has its origins as the Dealer Services division of Automatic Data P ...
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George T
George may refer to: People * George (given name) * George (surname) * George (singer), American-Canadian singer George Nozuka, known by the mononym George * George Washington, First President of the United States * George W. Bush, 43rd President of the United States * George H. W. Bush, 41st President of the United States * George V, King of Great Britain, Ireland, the British Dominions and Emperor of India from 1910-1936 * George VI, King of Great Britain, Ireland, the British Dominions and Emperor of India from 1936-1952 * Prince George of Wales * George Papagheorghe also known as Jorge / GEØRGE * George, stage name of Giorgio Moroder * George Harrison, an English musician and singer-songwriter Places South Africa * George, Western Cape ** George Airport United States * George, Iowa * George, Missouri * George, Washington * George County, Mississippi * George Air Force Base, a former U.S. Air Force base located in California Characters * George (Peppa Pig), a 2-year-old pig ...
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Chemistry Development Kit
The Chemistry Development Kit (CDK) is computer software, a library in the programming language Java, for chemoinformatics and bioinformatics. It is available for Windows, Linux, Unix, and macOS. It is free and open-source software distributed under the GNU Lesser General Public License (LGPL) 2.0. History The CDK was created by Christoph Steinbeck, Egon Willighagen and Dan Gezelter, then developers of Jmol and JChemPaint, to provide a common code base, on 27–29 September 2000 at the University of Notre Dame. The first source code release was made on 11 May 2011. Since then more than 100 people have contributed to the project, leading to a rich set of functions, as given below. Between 2004 and 2007, ''CDK News'' was the project's newsletter of which all articles are available from a public archive. Due to an unsteady rate of contributions, the newsletter was put on hold. Later, unit testing, code quality checking, and Javadoc validation was introduced. Rajarshi Guha developed ...
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Chung Do Kwan
Chung Do Kwan, created by Won Kuk Lee in 1944, is one of the first of nine schools or '' kwan'' teaching Tang Soo Do. Later, the school began to teach what came to be known as taekwondo. This style of Tang Soo Do is known for its overall power and emphasis on kicks to the head. Founding The Chung Do Kwan (; "Blue Way School") name was first used by Won Kuk Lee. Lee had studied Taekkyon in An Gup Dong (a neighborhood in Seoul), karate with Sensei Gichin Funakoshi in Okinawa, and kung fu at centers in Henan and Shanghai in China. Lee earned 4th dan ranking in Shotokan karate. According to Yong Taek Chung (a student of Lee) "it is probable that he did practice in secret as a teenager because he told this author that when he first started training he and his first teachers would not exchange names due to possible consequences if someone got caught." Chung Do Kwan was the second oldest of the martial arts schools, or "kwans", that were established following the Japanese Occupation ...
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Complete Knock Down
A knock-down kit (also knockdown kit, knocked-down kit, or simply knockdown or KD) is a collection of parts required to assemble a product. The parts are typically manufactured in one country or region, then exported to another country or region for final assembly. A common form of knock-down is a complete knock-down (CKD), which is a kit of entirely unassembled parts of a product. It is also a method of supplying parts to a market, particularly in shipping to foreign nations, and serves as a way of counting or pricing. CKD is a common practice in the automotive, bus, heavy truck, and rail vehicle industries, as well as electronics, furniture and other products. Businesses sell knocked-down kits to their foreign affiliates or licensees for various reasons, including the avoidance of import taxes, to receive tax preferences for providing local manufacturing jobs, or even to be considered as a bidder at all (for example, in public transport projects with "buy national" rules). A ...
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Curses Development Kit
CDK is a library written in C that provides a collection of widgets for text user interfaces (TUI) development. The widgets wrap ncurses functionality to make writing full screen curses programs faster. Perl Perl is a family of two high-level, general-purpose, interpreted, dynamic programming languages. "Perl" refers to Perl 5, but from 2000 to 2019 it also referred to its redesigned "sister language", Perl 6, before the latter's name was offici ... and Python bindings are also available. There are two versions of the library. It was originally written by Mike Glover, introduced as version 4.6 in comp.sources.unix. The other version was extended beginning in May 1999 by Thomas Dickey. Programs that use CDK Password Management SystemA console based password management program See also * Dialog (software) References External links * Application programming interfaces Software that uses ncurses Software using the BSD license Text user interface libraries Widg ...
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Cyclin-dependent Kinase
Cyclin-dependent kinases (CDKs) are the families of protein kinases first discovered for their role in regulating the cell cycle. They are also involved in regulating transcription, mRNA processing, and the differentiation of nerve cells. They are present in all known eukaryotes, and their regulatory function in the cell cycle has been evolutionarily conserved. In fact, yeast cells can proliferate normally when their CDK gene has been replaced with the homologous human gene. CDKs are relatively small proteins, with molecular weights ranging from 34 to 40 kDa, and contain little more than the kinase domain. By definition, a CDK binds a regulatory protein called a cyclin. Without cyclin, CDK has little kinase activity; only the cyclin-CDK complex is an active kinase but its activity can be typically further modulated by phosphorylation and other binding proteins, like p27. CDKs phosphorylate their substrates on serines and threonines, so they are serine-threonine kinases. The c ...
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Chronic Kidney Disease
Chronic kidney disease (CKD) is a type of kidney disease in which a gradual loss of kidney function occurs over a period of months to years. Initially generally no symptoms are seen, but later symptoms may include leg swelling, feeling tired, vomiting, loss of appetite, and confusion. Complications can relate to hormonal dysfunction of the kidneys and include (in chronological order) high blood pressure (often related to activation of the renin–angiotensin system system), bone disease, and anemia. Additionally CKD patients have markedly increased cardiovascular complications with increased risks of death and hospitalization. Causes of chronic kidney disease include diabetes, high blood pressure, glomerulonephritis, and polycystic kidney disease. Risk factors include a family history of chronic kidney disease. Diagnosis is by blood tests to measure the estimated glomerular filtration rate (eGFR), and a urine test to measure albumin. Ultrasound or kidney biopsy may be performe ...
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