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CALGB
Cancer and Leukemia Group B (CALGB; former name: Acute Leukemia Group B, ALGB) is a cancer research cooperative group in the United States. CALGB research is focused on seven major disease areas: leukemia, lymphoma, breast cancer, lung cancer, gastrointestinal malignancies, genito-urinary malignancies, and melanoma. In each of these areas, multi-modality treatment programs are designed by national experts. CALGB is headquartered at the University of Chicago in Chicago, Illinois and maintains its statistical centers at Mayo Clinic in Rochester, Minnesota and Duke University in Durham, North Carolina. History The group that was to become known as the CALGB got its roots when James F. Holland initiated a clinical trial for acute leukemia in 1953 while at the National Cancer Institute. In 1954, before the trial was complete, Holland moved to Roswell Park Comprehensive Cancer Center (then known as Roswell Park Memorial Institute), but the new chief of oncology Gordon Zubrod at the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Calgb Logo
Cancer and Leukemia Group B (CALGB; former name: Acute Leukemia Group B, ALGB) is a cancer research cooperative group in the United States. CALGB research is focused on seven major disease areas: leukemia, lymphoma, breast cancer, lung cancer, gastrointestinal malignancies, genito-urinary malignancies, and melanoma. In each of these areas, multi-modality treatment programs are designed by national experts. CALGB is headquartered at the University of Chicago in Chicago, Illinois and maintains its statistical centers at Mayo Clinic in Rochester, Minnesota and Duke University in Durham, North Carolina. History The group that was to become known as the CALGB got its roots when James F. Holland initiated a clinical trial for acute leukemia in 1953 while at the National Cancer Institute. In 1954, before the trial was complete, Holland moved to Roswell Park Comprehensive Cancer Center (then known as Roswell Park Memorial Institute), but the new chief of oncology Gordon Zubrod at the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Emil Frei
Emil "Tom" Frei III (February 21, 1924 – April 30, 2013) was an American physician and oncologist. He was the former director and former physician-in-chief of the Dana–Farber Cancer Institute in Boston, Massachusetts. He was also the Richard and Susan Smith Distinguished Professor of Medicine at Harvard Medical School. Early life and education Frei was born in 1924 in St. Louis. His family owned the stained glass manufacturer Emil Frei & Associates. Frei completed an accelerated pre-med Colgate University in 1944 after only 2 years of study and his medical degree from Yale University in 1948. Career He interned at Firmin Desloge Hospital, now St. Louis University Hospital in St. Louis, Missouri and served as a physician in the Korean War. He worked at the National Cancer Institute from 1955 to 1965 and the M. D. Anderson Cancer Center from 1965 to 1972; while at M.D. Anderson he was the founding director of the Department of Development Therapeutics, which evolved int ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Quality Assurance Review Center
The Imaging and Radiation Oncology Core (IROC) is a center for the evaluation of data produced by clinical trials funded by the National Cancer Institute, as part of the National Clinical Trials Network "to provide integrated radiation oncology and diagnostic imaging quality control programs... thereby assuring high quality data for clinical trials designed to improve the clinical outcomes for cancer patients worldwide." Centers There are currently five centers: IROC Houston QA Center, at the MD Anderson Cancer Center IROC Ohio QA Center, at Ohio State University Wexner Medical Center and James Comprehensive Cancer Center. IROC Rhode Island QA Center in Lincoln, Rhode Island, administered by the University of Massachusetts Medical School IROC Philadelphia (RT) QA Center, at the ACR Research center in Philadelphia, IROC Philadelphia (Imaging) QA Center, at the ACR Research center in Philadelphia, IROC St Louis QA Center at Washington University History The history of the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alliance For Clinical Trials In Oncology
The Alliance for Clinical Trials in Oncology is a national clinical trials network sponsored by the National Cancer Institute (NCI) that consists of about 10,000 cancer specialists at hospitals, medical centers, and community clinics across the United States and Canada. The Alliance develops and conducts clinical trials with promising new cancer therapies, and utilizes scientific research to develop treatment and prevention strategies for cancer, as well as researching methods to alleviate side effects of cancer and cancer treatments. The Alliance seeks to reduce the impact of cancer on people by uniting a broad community of scientists and clinicians from many disciplines, committed to discovering, validating and disseminating effective strategies for the prevention and treatment of cancer. The Alliance conducts trials in the following disease and modality areas: breast, gastrointestinal (GI), genitourinary (GU), leukemia, lymphoma, myeloma, neuro-oncology, respiratory, exper ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Southwest Oncology Group
SWOG (formerly the Southwest Oncology Group) is a National Cancer Institute (NCI) supported organization that conducts clinical trials in adult cancers. Comprising more than 4,000 cancer researchers at more than 650 institutions across the United States and Canada, it is one of the largest of the NCI's clinical trial cooperative groups. Member institutions include 24 of the NCI-designated cancer centers, many university medical centers, private institutions, and Community Clinical Oncology Programs. SWOG is headquartered at the Oregon Health & Science University in Portland, with an operations office in San Antonio, Texas and a statistical center in Seattle, Washington. SWOG was created by the NCI in 1956 as the Southwest Cancer Chemotherapy Study Group (SWCCSG) and was headquartered in Houston, Texas. Its primary purpose was to study leukemia, a cancer of the blood which primarily affects children. Then in 1958, the NCI directed the SWCCSG to include the study of adult cance ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Breast Cancer
Breast cancer is cancer that develops from breast tissue. Signs of breast cancer may include a lump in the breast, a change in breast shape, dimpling of the skin, milk rejection, fluid coming from the nipple, a newly inverted nipple, or a red or scaly patch of skin. In those with distant spread of the disease, there may be bone pain, swollen lymph nodes, shortness of breath, or yellow skin. Risk factors for developing breast cancer include obesity, a lack of physical exercise, alcoholism, hormone replacement therapy during menopause, ionizing radiation, an early age at first menstruation, having children late in life or not at all, older age, having a prior history of breast cancer, and a family history of breast cancer. About 5–10% of cases are the result of a genetic predisposition inherited from a person's parents, including BRCA1 and BRCA2 among others. Breast cancer most commonly develops in cells from the lining of milk ducts and the lobules that supply these ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gordon Zubrod
Charles Gordon Zubrod (January 22, 1914 – January 19, 1999) was an American oncologist who played a prominent role in the introduction of chemotherapy for cancer. He was one of the recipients of the 1972 Albert Lasker Awards in recognition of his contributions to the field, amongst many other doctorates and awards. Life and work Zubrod, an alumnus of the Georgetown Preparatory School (class of 1932), the College of the Holy Cross (class of 1936), and Columbia University College of Physicians and Surgeons (1940 class), served in the U.S. army medical corps during World War II, where he worked on a replacement for quinine in the treatment of malaria. The unit eventually discovered chloroquine. In 1946 he commenced work at Johns Hopkins University Medical School, and was appointed assistant professor of medicine and director of research at Saint Louis University in 1953. This position lasted briefly: he became clinical director of the National Institutes of Health in 1954 and b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Eastern Cooperative Oncology Group
The Eastern Cooperative Oncology Group (ECOG) began in 1955 as one of the first publicly funded cooperative groups to perform multi-center clinical trials for cancer research. A cooperative group in oncology constitutes a large network of private and public medical institutions developing protocols for cancer treatments. Institutional members include universities, medical centers, governments, and other cooperative groups. Research results are often provided through scientific publications, but the group also works closely with the pharmaceutical industry to test potential cancer drugs. According to ECOG's website, there are "more than 90 active clinical trials in all types of adult malignancies. Annual accrual is 6,000 patients, with more than 20,000 patients in follow-up." ECOG's coordinating center is based in Boston, Massachusetts while its Group Chair's office is located in Philadelphia, Pennsylvania Philadelphia, often called Philly, is the largest city in th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Children's Oncology Group
The Children's Oncology Group (COG), a clinical trials group supported by the National Cancer Institute (NCI), is the world's largest organization devoted exclusively to pediatric cancer research. The COG conducts a spectrum of clinical research and translational research trials for infants, children, adolescents, and young adults with cancer. Almost all centers that treat children with cancer in the US and Canada are part of the COG, with more than 200 centers in the United States, Canada, Switzerland, the Netherlands, Australia, and New Zealand. The member institutions have multidisciplinary teams consisting of physicians, research scientists, nurses, psychologists, pharmacists and other specialists. The group, with more than 7,500 experts worldwide, has nearly 100 active clinical-translational trials open at any given time. These trials include treatment for many types of childhood cancers, studies aimed at determining the underlying biology of these diseases, and trials invo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Diagnostic Imaging
Medical imaging is the technique and process of imaging the interior of a body for clinical analysis and medical intervention, as well as visual representation of the function of some organs or tissues (physiology). Medical imaging seeks to reveal internal structures hidden by the skin and bones, as well as to diagnose and treat disease. Medical imaging also establishes a database of normal anatomy and physiology to make it possible to identify abnormalities. Although imaging of removed organs and tissues can be performed for medical reasons, such procedures are usually considered part of pathology instead of medical imaging. Measurement and recording techniques that are not primarily designed to produce images, such as electroencephalography (EEG), magnetoencephalography (MEG), electrocardiography (ECG), and others, represent other technologies that produce data susceptible to representation as a parameter graph versus time or maps that contain data about the measurement lo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Radiotherapy
Radiation therapy or radiotherapy, often abbreviated RT, RTx, or XRT, is a therapy using ionizing radiation, generally provided as part of cancer treatment to control or kill malignant cells and normally delivered by a linear accelerator. Radiation therapy may be curative in a number of types of cancer if they are localized to one area of the body. It may also be used as part of adjuvant therapy, to prevent tumor recurrence after surgery to remove a primary malignant tumor (for example, early stages of breast cancer). Radiation therapy is synergistic with chemotherapy, and has been used before, during, and after chemotherapy in susceptible cancers. The subspecialty of oncology concerned with radiotherapy is called radiation oncology. A physician who practices in this subspecialty is a radiation oncologist. Radiation therapy is commonly applied to the cancerous tumor because of its ability to control cell growth. Ionizing radiation works by damaging the DNA of cancerous tissue l ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lincoln, Rhode Island
Lincoln is a town in Providence County, Rhode Island, United States. The population was 22,529 at the 2020 census. Lincoln is located in northeastern Rhode Island, north of Providence. Lincoln is part of the Providence metropolitan statistical area and the Greater Boston combined statistical area. Lincoln was settled in the 17th century as part of the Louisquisset grant, and several colonial stone-enders still exist in the town. Lincoln Woods State Park is located within the town. Limestone quarrying has occurred there since colonial times at the village of Lime Rock. Lincoln was a part of the town of Smithfield until 1871, when it was split off and named in honor of Abraham Lincoln. Lincoln became an important mill town in the late 19th century, with many textile factories running along the Blackstone River. Lincoln's villages include Manville, Albion, Lime Rock, Lonsdale, Fairlawn, Quinnville, and Saylesville. In 2008, the town was ranked #63 in Money Magazine's "Best P ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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