Anadenanthera
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Anadenanthera
''Anadenanthera'' is a genus of South American trees in the Legume family, Fabaceae. The genus contains two to four species, including '' A. colubrina'' and '' A. peregrina''. These trees respectively are known to the western world primarily as sources of the hallucinogenic snuffs vilca/cebil and yopo/cohoba. The main active constituent of ''Anadenanthera'' is bufotenin. Species *''Anadenanthera colubrina'' ** ''Anadenanthera colubrina'' var. ''cebil'' ** ''Anadenanthera colubrina'' var. ''colubrina'' *'' Anadenanthera peregrina'' ** ''Anadenanthera peregrina'' var. ''falcata'' ** ''Anadenanthera peregrina'' var. ''peregrina'' Chemical compounds Chemical compounds contained in ''Anadenanthera'' include: * 5-Methoxy-N,N-dimethyltryptamine, bark * Serotonin * N-Methyl-serotonin *5-Methoxy-N-methyltryptamine, bark *Bufotenin, seeds, bark *Bufotenine N-oxide, seeds *N,N-Dimethyltryptamine, seeds, pods, bark *N,N-Dimethyltryptamine-N-oxide, Seeds *N- Methyltr ...
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Yopo
''Anadenanthera peregrina'', also known as yopo, jopo, cohoba, parica or calcium tree, is a perennial tree of the genus ''Anadenanthera'' native to the Caribbean and South America. It grows up to tall, and has a horny bark. Its flowers grow in small, pale yellow to white spherical clusters resembling Acacia (e.g. wattle) inflorescences. It is an entheogen which has been used in healing ceremonies and rituals for thousands of years in northern South America and the Caribbean. Although the seeds of the yopo tree were originally gathered from the wild, increased competition between tribes over access to the seeds led to it being intentionally cultivated and transported elsewhere, expanding the plant's distribution through introduction to areas beyond its original native range. Related species This plant is almost identical to that of a related tree, ''Anadenanthera colubrina'', commonly known as cebíl or vilca. The beans of ''A. colubrina'' have a similar chemical makeup as ' ...
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Anadenanthera Peregrina
''Anadenanthera peregrina'', also known as yopo, jopo, cohoba, parica or calcium tree, is a perennial tree of the genus ''Anadenanthera'' native to the Caribbean and South America. It grows up to tall, and has a horny bark. Its flowers grow in small, pale yellow to white spherical clusters resembling Acacia (e.g. wattle) inflorescences. It is an entheogen which has been used in healing ceremonies and rituals for thousands of years in northern South America and the Caribbean. Although the seeds of the yopo tree were originally gathered from the wild, increased competition between tribes over access to the seeds led to it being intentionally cultivated and transported elsewhere, expanding the plant's distribution through introduction to areas beyond its original native range. Related species This plant is almost identical to that of a related tree, ''Anadenanthera colubrina'', commonly known as cebíl or vilca. The beans of ''A. colubrina'' have a similar chemical makeup as '' ...
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Anadenanthera Colubrina
''Anadenanthera colubrina'' (also known as vilca, huilco, huilca, wilco, willka, curupay, curupau, cebil, or angico) is a South American tree closely related to yopo, or ''Anadenanthera peregrina''. It grows to tall and the trunk is very thorny. The leaves are mimosa-like, up to in length and they fold up at night. In Argentina, ''A. colubrina'' produces flowers from September to December and bean pods from September to July. In Brazil ''A. colubrina'' has been given "high priority" conservation status. Nomenclature ''Anadenanthera colubrina'' is known by many names throughout South America. In Peru it is known as ''willka'' (also spelled ''wilca,'' ''vilca'' and ''huilca'') which in the Quechua languages means "sacred". Geography ''A. colubrina'' is found in Argentina, Bolivia, Brazil, Ecuador, Paraguay, Peru, Cuba, and Mauritius. Natural growing conditions ''A. colubrina'' grows at altitudes of about with roughly per year of precipitation and a mean temperature ...
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Anadenanthera Colubrina Var
''Anadenanthera'' is a genus of South American trees in the Legume family, Fabaceae. The genus contains two to four species, including '' A. colubrina'' and '' A. peregrina''. These trees respectively are known to the western world primarily as sources of the hallucinogenic snuffs vilca/cebil and yopo/cohoba. The main active constituent of ''Anadenanthera'' is bufotenin. Species *''Anadenanthera colubrina'' ** ''Anadenanthera colubrina'' var. ''cebil'' ** ''Anadenanthera colubrina'' var. ''colubrina'' *'' Anadenanthera peregrina'' ** ''Anadenanthera peregrina'' var. ''falcata'' ** ''Anadenanthera peregrina'' var. ''peregrina'' Chemical compounds Chemical compounds contained in ''Anadenanthera'' include: * 5-Methoxy-N,N-dimethyltryptamine, bark * Serotonin * N-Methyl-serotonin *5-Methoxy-N-methyltryptamine, bark *Bufotenin, seeds, bark *Bufotenine N-oxide, seeds *N,N-Dimethyltryptamine, seeds, pods, bark *N,N-Dimethyltryptamine-N-oxide, Seeds *N- Methyltry ...
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Anadenanthera
''Anadenanthera'' is a genus of South American trees in the Legume family, Fabaceae. The genus contains two to four species, including '' A. colubrina'' and '' A. peregrina''. These trees respectively are known to the western world primarily as sources of the hallucinogenic snuffs vilca/cebil and yopo/cohoba. The main active constituent of ''Anadenanthera'' is bufotenin. Species *''Anadenanthera colubrina'' ** ''Anadenanthera colubrina'' var. ''cebil'' ** ''Anadenanthera colubrina'' var. ''colubrina'' *'' Anadenanthera peregrina'' ** ''Anadenanthera peregrina'' var. ''falcata'' ** ''Anadenanthera peregrina'' var. ''peregrina'' Chemical compounds Chemical compounds contained in ''Anadenanthera'' include: * 5-Methoxy-N,N-dimethyltryptamine, bark * Serotonin * N-Methyl-serotonin *5-Methoxy-N-methyltryptamine, bark *Bufotenin, seeds, bark *Bufotenine N-oxide, seeds *N,N-Dimethyltryptamine, seeds, pods, bark *N,N-Dimethyltryptamine-N-oxide, Seeds *N- Methyltr ...
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Anadenanthera Peregrina Var
''Anadenanthera'' is a genus of South American trees in the Legume family, Fabaceae. The genus contains two to four species, including '' A. colubrina'' and '' A. peregrina''. These trees respectively are known to the western world primarily as sources of the hallucinogenic snuffs vilca/cebil and yopo/cohoba. The main active constituent of ''Anadenanthera'' is bufotenin. Species *''Anadenanthera colubrina'' ** ''Anadenanthera colubrina'' var. ''cebil'' ** ''Anadenanthera colubrina'' var. ''colubrina'' *'' Anadenanthera peregrina'' ** ''Anadenanthera peregrina'' var. ''falcata'' ** ''Anadenanthera peregrina'' var. ''peregrina'' Chemical compounds Chemical compounds contained in ''Anadenanthera'' include: * 5-Methoxy-N,N-dimethyltryptamine, bark * Serotonin * N-Methyl-serotonin *5-Methoxy-N-methyltryptamine, bark *Bufotenin, seeds, bark *Bufotenine N-oxide, seeds *N,N-Dimethyltryptamine, seeds, pods, bark *N,N-Dimethyltryptamine-N-oxide, Seeds *N- Methyltry ...
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Bufotenin
Bufotenin (5-HO-DMT, bufotenine) is a tryptamine derivative - more specifically, a DMT derivative - related to the neurotransmitter serotonin. It is an alkaloid found in some species of toads (especially the skin), mushrooms and plants. The name bufotenin originates from the toad genus ''Bufo'', which includes several species of psychoactive toads, most notably ''Incilius alvarius'', that secrete bufotoxins from their parotoid glands. Bufotenin is similar in chemical structure to the psychedelics psilocin (4-HO-DMT), 5-MeO-DMT, and DMT, chemicals which also occur in some of the same fungus, plant, and animal species as bufotenin. Nomenclature Bufotenin (bufotenine) is also known by the chemical names 5-hydroxy-''N'',''N''-dimethyltryptamine (5-HO-DMT), ''N'',''N''-dimethyl-5-hydroxytryptamine, dimethyl serotonin, and mappine. History Bufotenin was isolated from toad skin, and named by the Austrian chemist Handovsky at the University of Prague during World War I. The struct ...
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Bufotenin
Bufotenin (5-HO-DMT, bufotenine) is a tryptamine derivative - more specifically, a DMT derivative - related to the neurotransmitter serotonin. It is an alkaloid found in some species of toads (especially the skin), mushrooms and plants. The name bufotenin originates from the toad genus ''Bufo'', which includes several species of psychoactive toads, most notably ''Incilius alvarius'', that secrete bufotoxins from their parotoid glands. Bufotenin is similar in chemical structure to the psychedelics psilocin (4-HO-DMT), 5-MeO-DMT, and DMT, chemicals which also occur in some of the same fungus, plant, and animal species as bufotenin. Nomenclature Bufotenin (bufotenine) is also known by the chemical names 5-hydroxy-''N'',''N''-dimethyltryptamine (5-HO-DMT), ''N'',''N''-dimethyl-5-hydroxytryptamine, dimethyl serotonin, and mappine. History Bufotenin was isolated from toad skin, and named by the Austrian chemist Handovsky at the University of Prague during World War I. The struct ...
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Dimethyltryptamine
''N'',''N''-Dimethyltryptamine (DMT or ''N'',''N''-DMT, SPL026) is a substituted tryptamine that occurs in many plants and animals, including human beings, and which is both a derivative and a structural analog of tryptamine. It is used as a psychedelic drug and prepared by various cultures for ritual purposes as an entheogen. DMT has a rapid onset, intense effects, and a relatively short duration of action. For those reasons, DMT was known as the "business trip" during the 1960s in the United States, as a user could access the full depth of a psychedelic experience in considerably less time than with other substances such as LSD or psilocybin mushrooms. DMT can be inhaled, ingested, or injected and its effects depend on the dose, as well as the mode of administration. When inhaled or injected, the effects last a short period of time: about five to 15 minutes. Effects can last three hours or more when orally ingested along with a monoamine oxidase inhibitor (MAOI), such as ...
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5-MeO-DMT
5-MeO-DMT (5-methoxy-''N'',''N''-dimethyltryptamine) or O-methyl-bufotenin is a psychedelic of the tryptamine class. It is found in a wide variety of plant species, and also is secreted by the glands of at least one toad species, the Colorado River toad. Like its close relatives DMT and bufotenin (5-HO-DMT), it has been used as an entheogen in South America. Slang terms include Five-methoxy, The power, and Toad venom. Chemistry 5-MeO-DMT was first synthesized in 1936, and in 1959 it was isolated as one of the psychoactive ingredients of '' Anadenanthera peregrina'' seeds used in preparing Yopo snuff. It was once believed to be a major component of the psychoactive effects of the snuff, although this has recently been shown to be unlikely, due to the limited or sometimes even non-existent quantity contained within the seeds, which instead achieve their psychoactivity from the ''O''-demethylated metabolite of 5-MeO-DMT, bufotenin. It is metabolized mainly by CYP2D6. Effects D ...
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Constantino Manuel Torres
Constantino Manuel Torres, known as Manuel Torres, is an archaeologist and ethnobotanist specialising in the ethnobotany of pre-columbian South America and the Caribbean. In particular, he has shed much light on the Taíno use of Anadenanthera snuff Cohoba Cohoba is a Taíno Indian transliteration for a ceremony in which the ground seeds of the ''cojóbana'' tree (''Anadenanthera'' spp.) were inhaled, the Y-shaped nasal snuff tube used to inhale the substance, and the psychoactive drug that was inha ..., its paraphernalia and associated archaeology. Selected published works *''The Use of Anadenanthera colubrina var. Cebil by Wichi (Mataco) Shamans of the Chaco Central, Argentina.'' Yearbook for ethnomedicine and the study of consciousness 5: 41–58, with David Repke as second author. Verläg für Wissenschaft und Bildung, Berlin, (1998). *''The role of cohoba in Taíno shamanism.'' Eleusis, n.s., no. 1: 38–50, Museo Civico di Rovereto, Trento, Italy, (1998). *''Exploring t ...
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Serotonin
Serotonin () or 5-hydroxytryptamine (5-HT) is a monoamine neurotransmitter. Its biological function is complex and multifaceted, modulating mood, cognition, reward, learning, memory, and numerous physiological processes such as vomiting and vasoconstriction. Approximately 90% of the serotonin that the body produces is in the intestinal tract. Biochemically, the indoleamine molecule derives from the amino acid tryptophan, via the (rate-limiting) hydroxylation of the 5 position on the ring (forming the intermediate 5-hydroxytryptophan), and then decarboxylation to produce serotonin. Serotonin is primarily found in the enteric nervous system located in the gastrointestinal tract (GI tract). However, it is also produced in the central nervous system (CNS), specifically in the raphe nuclei located in the brainstem, Merkel cells located in the skin, pulmonary neuroendocrine cells and taste receptor cells in the tongue. Additionally, serotonin is stored in blood platelets and is ...
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