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Bryan Williams (professor)
Bryan Raymond George Williams Hon. FRSNZ, FAA (born 1949) is a molecular biologist from New Zealand, with expertise in innate immunity and cancer biology. He is emeritus director and distinguished scientist at the Hudson Institute of Medical Research in Melbourne, Australia, and professor in the Department of Molecular and Translational Science at Monash University. Background and early career Williams graduated in 1973, from the University of Otago, New Zealand, with a Bachelor of Science (Honours) in microbiology. He was awarded his PhD from the department of microbiology, University of Otago in 1976. He then moved to the UK to undertake postdoctoral training at the National Institute for Medical Research in Mill Hill, London, where he worked on the biochemistry of interferon action. Research career In 1980, Williams relocated to Toronto, Canada, where he held positions at the Hospital for Sick Children and the University of Toronto. He continued to work on the mechanisms o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Molecular Biologist
Molecular biology is the branch of biology that seeks to understand the molecular basis of biological activity in and between cells, including biomolecular synthesis, modification, mechanisms, and interactions. The study of chemical and physical structure of biological macromolecules is known as molecular biology. Molecular biology was first described as an approach focused on the underpinnings of biological phenomena - uncovering the structures of biological molecules as well as their interactions, and how these interactions explain observations of classical biology. In 1945 the term molecular biology was used by physicist William Astbury. In 1953 Francis Crick, James Watson, Rosalind Franklin, and colleagues, working at Medical Research Council unit, Cavendish laboratory, Cambridge (now the MRC Laboratory of Molecular Biology), made a double helix model of DNA which changed the entire research scenario. They proposed the DNA structure based on previous research done by Ro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein Kinase R
Protein kinase RNA-activated also known as protein kinase R (PKR), interferon-induced, double-stranded RNA-activated protein kinase, or eukaryotic translation initiation factor 2-alpha kinase 2 (EIF2AK2) is an enzyme that in humans is encoded by the ''EIF2AK2'' gene. PKR protects against viral infections. Mechanism of action Protein kinase-R is activated by double-stranded RNA (dsRNA), introduced to the cells by a viral infection. PKR can also be activated by the protein PACT or by heparin. PKR contains an N-terminal dsRNA binding domain (dsRBD) and a C-terminal kinase domain, that gives it pro-apoptotic (cell-killing) functions. The dsRBD consists of two tandem copies of a conserved double stranded RNA binding motif, dsRBM1 and dsRBM2. PKR is induced by interferon in a latent state. Binding to dsRNA is believed to activate PKR by inducing dimerization and subsequent auto-phosphorylation reactions. In situations of viral infection, the dsRNA created by viral replication and g ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Monash University Faculty
Monash may refer to: __NOTOC__ Places Australia Australian Capital Territory * Monash, Australian Capital Territory, a suburb of Canberra South Australia * Monash, South Australia, a town Victoria * City of Monash, a municipality * Division of Monash, an Australian Electoral Division * Monash College, Melbourne * Monash Freeway, a road linking Melbourne to Gippsland * Monash Medical Centre, a hospital and research centre in Melbourne * Monash Province, an electorate of the Victorian Legislative Council until 2006 * Monash Special Developmental School, a school * Monash University, a public research university in Melbourne Israel * Kfar Monash, an agricultural settlement in central Israel People * John Monash (1865–1931), Australian World War I general * Paul Monash (1917–2003), American producer and screenwriter Other uses * .monash This list of Internet top-level domains (TLD) contains top-level domains, which are those domains in the DNS root zone of the Domain Nam ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
New Zealand Chief Executives
New is an adjective referring to something recently made, discovered, or created. New or NEW may refer to: Music * New, singer of K-pop group The Boyz Albums and EPs * ''New'' (album), by Paul McCartney, 2013 * ''New'' (EP), by Regurgitator, 1995 Songs * "New" (Daya song), 2017 * "New" (Paul McCartney song), 2013 * "New" (No Doubt song), 1999 *"new", by Loona from '' Yves'', 2017 *"The New", by Interpol from ''Turn On the Bright Lights'', 2002 Acronyms * Net economic welfare, a proposed macroeconomic indicator * Net explosive weight, also known as net explosive quantity * Network of enlightened Women, a conservative university women's organization * Next Entertainment World, a South Korean film distribution company Identification codes * Nepal Bhasa language ISO 639 language code * New Century Financial Corporation (NYSE stock abbreviation) * Northeast Wrestling, a professional wrestling promotion in the northeastern United States Transport * New Orleans Lakefront Ai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1949 Births
Events January * January 1 – A United Nations-sponsored ceasefire brings an end to the Indo-Pakistani War of 1947. The war results in a stalemate and the division of Kashmir, which still continues as of 2022. * January 2 – Luis Muñoz Marín becomes the first democratically elected Governor of Puerto Rico. * January 11 – The first "networked" television broadcasts take place, as KDKA-TV in Pittsburgh, Pennsylvania goes on the air, connecting east coast and mid-west programming in the United States. * January 16 – Şemsettin Günaltay forms the new government of Turkey. It is the 18th government, last One-party state, single party government of the Republican People's Party. * January 17 – The first Volkswagen Beetle, VW Type 1 to arrive in the United States, a 1948 model, is brought to New York City, New York by Dutch businessman Ben Pon Sr., Ben Pon. Unable to interest dealers or importers in the Volkswagen, Pon sells the sample car to pay his ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Journal Of Virology
The ''Journal of Virology'' is a biweekly peer-reviewed scientific journal that covers research concerning all aspects of virology. It was established in 1967 and is published by the American Society for Microbiology. Research papers are available free online four months after print publication. The editor-in-chief is Rozanne M. Sandri-Goldin (University of California, Irvine, California) (2012–present). Past editors-in-chief include Lynn W. Enquist (2002–2012), Thomas Shenk (1994–2002), and Arnold J. Levine (1984–1994).American Society for Microbiology: ASM Announces Appointments of New Editors In Chief for CMR and JVI (accessed 23 January 2013)Enquist LW. (2012) Ten years under the JVI flag. ''Journal of Virology'' ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Monash Institute Of Medical Research
The Monash Institute of Medical Research (MIMR), was an Australian medical research institute located in the Melbourne suburb of Clayton, Victoria, consisting of 400 scientists and students belonging to the Faculty of Medicine, Nursing and Health Sciences at Monash University. In January 2014 the Institute merged with Prince Henry's Institute of Medical Research and has since been renamed the Hudson Institute of Medical Research. The focus of the work of MIMR was research into the characterisation and application of stem cells, the cause and treatment of inflammation and cancer, and the improvement of women's, men's and children's health. The reputation of MIMR has been built on advances in assisted human reproduction, the reduction of Sudden infant death syndrome (SIDS), advances in stem cell research and the treatment of arthritis. Together with the collaborative resources of Monash University and the Monash Health Research Precinct, the impact of MIMR research by translation ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Small Interfering RNA
Small interfering RNA (siRNA), sometimes known as short interfering RNA or silencing RNA, is a class of double-stranded RNA at first non-coding RNA molecules, typically 20-24 (normally 21) base pairs in length, similar to miRNA, and operating within the RNA interference (RNAi) pathway. It interferes with the expression of specific genes with complementary nucleotide sequences by degrading mRNA after transcription, preventing translation. Text was copied from this source, which is available under Creative Commons Attribution 4.0 International License Structure Naturally occurring siRNAs have a well-defined structure that is a short (usually 20 to 24- bp) double-stranded RNA (dsRNA) with phosphorylated 5' ends and hydroxylated 3' ends with two overhanging nucleotides. The Dicer enzyme catalyzes production of siRNAs from long dsRNAs and small hairpin RNAs. siRNAs can also be introduced into cells by transfection. Since in principle any gene can be knocked down by a syntheti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ohio
Ohio () is a state in the Midwestern region of the United States. Of the fifty U.S. states, it is the 34th-largest by area, and with a population of nearly 11.8 million, is the seventh-most populous and tenth-most densely populated. The state's capital and largest city is Columbus, with the Columbus metro area, Greater Cincinnati, and Greater Cleveland being the largest metropolitan areas. Ohio is bordered by Lake Erie to the north, Pennsylvania to the east, West Virginia to the southeast, Kentucky to the southwest, Indiana to the west, and Michigan to the northwest. Ohio is historically known as the "Buckeye State" after its Ohio buckeye trees, and Ohioans are also known as "Buckeyes". Its state flag is the only non-rectangular flag of all the U.S. states. Ohio takes its name from the Ohio River, which in turn originated from the Seneca word ''ohiːyo'', meaning "good river", "great river", or "large creek". The state arose from the lands west of the Appalachian Mountai ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cleveland Clinic
Cleveland Clinic is a nonprofit American academic medical center based in Cleveland, Ohio. Owned and operated by the Cleveland Clinic Foundation, an Ohio nonprofit corporation established in 1921, it runs a 170-acre (69 ha) campus in Cleveland, as well as 11 affiliated hospitals, 19 family health centers in Northeast Ohio, and hospitals in Florida and Nevada. International operations include the Cleveland Clinic Abu Dhabi hospital in the United Arab Emirates and Cleveland Clinic Canada, which has two executive health and sports medicine clinics in Toronto."Facts & Figures" Cleveland Clinic. Another hospital campus in the United Kingdom, Cleveland Clinic London, opened to outpatients in 2021 and is scheduled to fully open in 2022. Tomislav Mihaljevic is the president and CEO. Cleveland Cl ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Wilms Tumour
Wilms' tumor or Wilms tumor, also known as nephroblastoma, is a cancer of the kidneys that typically occurs in children, rarely in adults.; and occurs most commonly as a renal tumor in child patients. It is named after Max Wilms, the German surgeon (1867–1918) who first described it. Approximately 650 cases are diagnosed in the U.S. annually. The majority of cases occur in children with no associated genetic syndromes; however, a minority of children with Wilms' tumor have a congenital abnormality. It is highly responsive to treatment, with about 90 percent of children being cured. Signs and symptoms Typical signs and symptoms of Wilms' tumor include the following: * a painless, palpable abdominal mass * loss of appetite * abdominal pain * fever * nausea and vomiting * blood in the urine (in about 20% of cases) * high blood pressure in some cases (especially if synchronous or metachronous bilateral kidney involvement) * Rarely as varicoceleErginel B, Vural S, Akın M, K ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
