|
Bruce H. Lipshutz
Bruce H. Lipshutz (born 1951) is an American chemist. He is a professor at the University of California, Santa Barbara. Biography Lipshutz received his undergraduate degree in chemistry from Binghamton University in 1973. His graduate work was supervised by Harry H. Wasserman at Yale. After a PhD degree in 1977, he spent two years at Harvard as a post-doctoral researcher in the group of Nobel Laureate E. J. Corey. Soon after, he accepted a position of Assistant Professor at UCSB rising to the ranks of Professor in 1987. He has received the Alfred P. Sloan Foundation Fellowship and the Camille & Henry Dreyfus Teacher-Scholar Award. In 2011 he was awarded Presidential Green Chemistry Award. He is Co-founder of Zymes LLC. Contributions Reagents *Aqueous Micellar Catalysis using TPGS-750-M and Nok. *Sustainable Palladium catalysis. * 2-(Trimethylsilyl)ethoxymethyl chloride: hydroxyl protecting group, selectively cleaved with fluoride ion under mild conditions. Di-(4-chlorobenzyl)az ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of California, Santa Barbara
The University of California, Santa Barbara (UC Santa Barbara or UCSB) is a Public university, public Land-grant university, land-grant research university in Santa Barbara County, California, Santa Barbara, California with 23,196 undergraduates and 2,983 graduate students enrolled in 2021–2022. It is part of the University of California 10-university system. Tracing its roots back to 1891 as an independent teachers' college, UCSB joined the University of California system in 1944, and is the third-oldest undergraduate campus in the system, after University of California, Berkeley, UC Berkeley and University of California, Los Angeles, UCLA. Located on a WWII-era Marine air station, UC Santa Barbara is organized into three undergraduate colleges (UCSB College of Letters and Science, College of Letters and Science, UCSB College of Engineering, College of Engineering, College of Creative Studies) and two graduate schools (Gevirtz Graduate School of Education and Bren School of E ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Stryker's Reagent
Stryker's reagent ( PPh3)CuHsub>6), also known as the Osborn complex, is a hexameric copper hydride ligated with triphenylphosphine. It is a brick red, air-sensitive solid. Stryker's reagent is a mildly hydridic reagent, used in homogeneous catalysis of conjugate reduction reactions of enones, enoates, and related substrates. Preparation and structure The compound is prepared by hydrogenation of copper(I) ''tert''-butoxide, generated in situ from copper(I) chloride and sodium ''tert''-butoxide. Other more convenient methods have been developed since its discovery. In terms of its structure, the compound is an octahedral cluster of Cu(PPh3) centres that are bonded by Cu---Cu and Cu---H interactions. Originally six of the eight faces were thought to be capped by hydride ligands. This structural assignment was revised in 2014; the hydrides are now best described as edge bridging rather than face bridging. Applications in organic synthesis The compound can effect regioselectiv ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Harvard University Staff
Harvard University is a private Ivy League research university in Cambridge, Massachusetts. Founded in 1636 as Harvard College and named for its first benefactor, the Puritan clergyman John Harvard, it is the oldest institution of higher learning in the United States and one of the most prestigious and highly ranked universities in the world. The university is composed of ten academic faculties plus Harvard Radcliffe Institute. The Faculty of Arts and Sciences offers study in a wide range of undergraduate and graduate academic disciplines, and other faculties offer only graduate degrees, including professional degrees. Harvard has three main campuses: the Cambridge campus centered on Harvard Yard; an adjoining campus immediately across Charles River in the Allston neighborhood of Boston; and the medical campus in Boston's Longwood Medical Area. Harvard's endowment is valued at $50.9 billion, making it the wealthiest academic institution in the world. Endowment inco ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Yale University Alumni
Yale University is a private research university in New Haven, Connecticut. Established in 1701 as the Collegiate School, it is the third-oldest institution of higher education in the United States and among the most prestigious in the world. It is a member of the Ivy League. Chartered by the Connecticut Colony, the Collegiate School was established in 1701 by clergy to educate Congregational ministers before moving to New Haven in 1716. Originally restricted to theology and sacred languages, the curriculum began to incorporate humanities and sciences by the time of the American Revolution. In the 19th century, the college expanded into graduate and professional instruction, awarding the first PhD in the United States in 1861 and organizing as a university in 1887. Yale's faculty and student populations grew after 1890 with rapid expansion of the physical campus and scientific research. Yale is organized into fourteen constituent schools: the original undergraduate colleg ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
21st-century American Chemists
The 1st century was the century spanning AD 1 ( I) through AD 100 ( C) according to the Julian calendar. It is often written as the or to distinguish it from the 1st century BC (or BCE) which preceded it. The 1st century is considered part of the Classical era, epoch, or historical period. The 1st century also saw the appearance of Christianity. During this period, Europe, North Africa and the Near East fell under increasing domination by the Roman Empire, which continued expanding, most notably conquering Britain under the emperor Claudius ( AD 43). The reforms introduced by Augustus during his long reign stabilized the empire after the turmoil of the previous century's civil wars. Later in the century the Julio-Claudian dynasty, which had been founded by Augustus, came to an end with the suicide of Nero in AD 68. There followed the famous Year of Four Emperors, a brief period of civil war and instability, which was finally brought to an end by Vespasian, ninth Roman em ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
1951 Births
Events January * January 4 – Korean War: Third Battle of Seoul – Chinese and North Korean forces capture Seoul for the second time (having lost the Second Battle of Seoul in September 1950). * January 9 – The Government of the United Kingdom announces abandonment of the Tanganyika groundnut scheme for the cultivation of peanuts in the Tanganyika Territory, with the writing off of £36.5M debt. * January 15 – In a court in West Germany, Ilse Koch, The "Witch of Buchenwald", wife of the commandant of the Buchenwald concentration camp, is sentenced to life imprisonment. * January 20 – Winter of Terror: Avalanches in the Alps kill 240 and bury 45,000 for a time, in Switzerland, Austria and Italy. * January 21 – Mount Lamington in Papua New Guinea erupts catastrophically, killing nearly 3,000 people and causing great devastation in Oro Province. * January 25 – Dutch author Anne de Vries releases the first volume of his children's novel '' Journey Through ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Coenzyme Q10
Coenzyme Q, also known as ubiquinone and marketed as CoQ10, is a coenzyme family that is ubiquitous in animals and most bacteria (hence the name ubiquinone). In humans, the most common form is coenzyme Q10 or ubiquinone-10. It is a 1,4-benzoquinone, where Q refers to the quinone chemical group and 10 refers to the number of isoprenyl chemical subunits in its tail. In natural ubiquinones, the number can be anywhere from 6 to 10. This family of fat-soluble substances, which resemble vitamins, is present in all respiring eukaryotic cells, primarily in the mitochondria. It is a component of the electron transport chain and participates in aerobic cellular respiration, which generates energy in the form of ATP. Ninety-five percent of the human body's energy is generated this way. Organs with the highest energy requirements—such as the heart, liver, and kidney—have the highest CoQ10 concentrations. There are three redox states of CoQ: fully oxidized (ubiquinone), semiquinone ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mitsunobu Reaction
The Mitsunobu reaction is an organic reaction that converts an alcohol into a variety of functional groups, such as an ester, using triphenylphosphine and an azodicarboxylate such as diethyl azodicarboxylate (DEAD) or diisopropyl azodicarboxylate (DIAD). Although DEAD and DIAD are most commonly used, there are a variety of other azodicarboxylates available which facilitate an easier workup and/or purification and in some cases, facilitate the use of more basic nucleophiles. It was discovered by Oyo Mitsunobu (1934–2003). Typical protocol is to add the phosphine and azodicarboxylate together at −10 °C, typically in THF or toluene, until a white precipitate forms. This white, cloudy suspension is the ylide. Then a solution of the nucleophile and alcohol are added together and the reaction can be, and in many cases is, heated to reflux. The alcohol reacts with the phosphine to create a good leaving group then undergoes an inversion of stereochemistry in classic SN2 fashion ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Binghamton University
The State University of New York at Binghamton (Binghamton University or SUNY Binghamton) is a public university, public research university with campuses in Binghamton, New York, Binghamton, Vestal, New York, Vestal, and Johnson City, New York. It is one of the four university centers in the State University of New York (SUNY) system. As of Fall 2020, 18,128 undergraduate and graduate students attended the university. Since its establishment in 1946, the school has evolved from a small liberal arts college to a large research university. It is Carnegie Classification of Institutions of Higher Education, classified among "R1: Doctoral Universities – Very high research activity". Binghamton's athletic teams are the Binghamton Bearcats, Bearcats and they compete in NCAA Division I, Division I of the National Collegiate Athletic Association (NCAA). The Bearcats are members of the America East Conference. History Establishment Binghamton University was established in 1946 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
2-(Trimethylsilyl)ethoxymethyl Chloride
2-(Trimethylsilyl)ethoxymethyl chloride (SEM-Cl) is an organochlorine compound with the formula C6H15ClOSi, which was developed by Bruce H. Lipshutz during his work on the synthesis of ''N''-methylmaysenine. It is used to protect hydroxyl group, which can be cleaved with fluoride in organic solvents selectively under mild conditions. Typically tetrabutylammonium fluoride and caesium fluoride can be used as deprotection reagents. Alternatives such as magnesium bromide, lithium tetrafluoroborate and boron trifluoride Boron trifluoride is the inorganic compound with the formula BF3. This pungent, colourless, and toxic gas forms white fumes in moist air. It is a useful Lewis acid and a versatile building block for other boron compounds. Structure and bondin ... etherate were also developed to deprotect SEM group. References Further reading * {{DEFAULTSORT:Trimethylsilyl)ethoxymethyl chloride, 2-( Organochlorides Trimethylsilyl compounds ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Alfred P
Alfred may refer to: Arts and entertainment *''Alfred J. Kwak'', Dutch-German-Japanese anime television series *Alfred (Arne opera), ''Alfred'' (Arne opera), a 1740 masque by Thomas Arne *Alfred (Dvořák), ''Alfred'' (Dvořák), an 1870 opera by Antonín Dvořák *"Alfred (Interlude)" and "Alfred (Outro)", songs by Eminem from the 2020 album ''Music to Be Murdered By'' Business and organisations * Alfred, a radio station in Shaftesbury, England *Alfred Music, an American music publisher *Alfred University, New York, U.S. *The Alfred Hospital, a hospital in Melbourne, Australia People * Alfred (name) includes a list of people and fictional characters called Alfred * Alfred the Great (848/49 – 899), or Alfred I, a king of the West Saxons and of the Anglo-Saxons Places Antarctica * Mount Alfred (Antarctica) Australia * Alfredtown, New South Wales * County of Alfred, South Australia Canada * Alfred and Plantagenet, Ontario * Alfred Island, Nunavut * Mount Alfred, British Colu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
