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Bongani Mayosi
Bongani Mawethu Mayosi BMedSci, MB ChB, FCP(SA), DPhil, (28 January 1967 – 27 July 2018) was a South African professor of cardiology He was the Dean of the Faculty of Health Sciences at the University of Cape Town and an A-rated National Research Foundation researcher. Prior to this, he was head of the Department of Medicine at the University of Cape Town and Groote Schuur Hospital. his research interests included rheumatic fever, tuberculous pericarditis and cardiomyopathy. He was a member of the Academy of Science of South Africa and a former President of the College of Physicians of South Africa and he headed numerous other biomedical organisations during his career. Early life At the youthful age of 15, he received the top marks in the Independent Transkei's matric exams. Career In 2017 he was elected to the US National Academy of Medicine. Professor Mayosi published over 400 peer-reviewed academic articles individually and collectively, including collabor ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bachelor Of Medical Sciences
A Bachelor of Medical Sciences (BMedSci, BMedSc, BSc(Med), BMSc) is an undergraduate academic degree involving study of a variety of disciplines related to human health leading to an in depth understanding of human biology and associated research skills such as study design, statistics and laboratory techniques. Such disciplines include biochemistry, cell biology, physiology, pharmacology or psychosocial aspects of health. It is an equivalent level qualification to the more commonly awarded Bachelor of Science (BSc). Graduates may enter a diverse range of roles including post-graduate study, higher education, the biotechnology industry, the pharmaceutical industry, consultancy roles, scientific communication, education or unrelated disciplines which make use of the broad range of transferable skills gained through this degree. Australia In Australia, the Bachelor of Medical Sciences (BMedSc) degree is offered by The University of Adelaide, Griffith University, University of New Sout ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cardiology
Cardiology () is a branch of medicine that deals with disorders of the heart and the cardiovascular system. The field includes medical diagnosis and treatment of congenital heart defects, coronary artery disease, heart failure, valvular heart disease and electrophysiology. Physicians who specialize in this field of medicine are called cardiologists, a specialty of internal medicine. Pediatric cardiologists are pediatricians who specialize in cardiology. Physicians who specialize in cardiac surgery are called cardiothoracic surgeons or cardiac surgeons, a specialty of general surgery. Specializations All cardiologists study the disorders of the heart, but the study of adult and child heart disorders each require different training pathways. Therefore, an adult cardiologist (often simply called "cardiologist") is inadequately trained to take care of children, and pediatric cardiologists are not trained to treat adult heart disease. Surgical aspects are not included in cardiology ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Arrhythmogenic Right Ventricular Dysplasia
Arrhythmogenic cardiomyopathy (ACM), arrhythmogenic right ventricular dysplasia (ARVD), or arrhythmogenic right ventricular cardiomyopathy (ARVC), most commonly is an inherited heart disease. ACM is caused by genetic defects of the parts of heart muscle (also called ''myocardium'' or ''cardiac muscle'') known as desmosomes, areas on the surface of heart muscle cells which link the cells together. The desmosomes are composed of several proteins, and many of those proteins can have harmful mutations. ARVC can also develop in intense endurance athletes in the absence of desmosomal abnormalities. Exercise-induced ARVC cause possibly is a result of excessive right ventricular wall stress during high intensity exercise. The disease is a type of non-ischemic cardiomyopathy that primarily involves the right ventricle, though cases of exclusive left ventricular disease have been reported. It is characterized by hypokinetic areas involving the free wall of the ventricle, with fibrofatt ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mutation
In biology, a mutation is an alteration in the nucleic acid sequence of the genome of an organism, virus, or extrachromosomal DNA. Viral genomes contain either DNA or RNA. Mutations result from errors during DNA or viral replication, mitosis, or meiosis or other types of damage to DNA (such as pyrimidine dimers caused by exposure to ultraviolet radiation), which then may undergo error-prone repair (especially microhomology-mediated end joining), cause an error during other forms of repair, or cause an error during replication (translesion synthesis). Mutations may also result from insertion or deletion of segments of DNA due to mobile genetic elements. Mutations may or may not produce detectable changes in the observable characteristics (phenotype) of an organism. Mutations play a part in both normal and abnormal biological processes including: evolution, cancer, and the development of the immune system, including junctional diversity. Mutation is the ultimate source o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Salim Yusuf
Salim Yusuf (born 26 November 1952) is an Indian-born Canadian physician, the Marion W. Burke Chair in Cardiovascular Disease at McMaster University Medical School. He is a cardiologist and epidemiologist. Early life and education Born in the town of Kottarakkara in Kerala, Yusuf studied medicine at St. John's Medical College in Bangalore and earned a DPhil at Oxford University as a Rhodes scholar. At Oxford, he also took part in research into cardiovascular disease. His doctoral thesis was titled "Beta adrenergic blockade in myocardial infarction" and his supervisor was Peter Sleight. Career In 1984, Yusuf moved to the National Institutes of Health in the United States, where he led clinical trials that showed the value of ACE inhibitors in people with left ventricular dysfunction and the optimal use of digoxin). He came to the Michael G. DeGroote School of Medicine at McMaster University in 1992 as director of the cardiology division. In 1999 McMaster created the Popul ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Peer Review
Peer review is the evaluation of work by one or more people with similar competencies as the producers of the work (peers). It functions as a form of self-regulation by qualified members of a profession within the relevant field. Peer review methods are used to maintain quality standards, improve performance, and provide credibility. In academia, scholarly peer review is often used to determine an academic paper's suitability for publication. Peer review can be categorized by the type of activity and by the field or profession in which the activity occurs, e.g., medical peer review. It can also be used as a teaching tool to help students improve writing assignments. Henry Oldenburg (1619–1677) was a German-born British philosopher who is seen as the 'father' of modern scientific peer review. Professional Professional peer review focuses on the performance of professionals, with a view to improving quality, upholding standards, or providing certification. In academia, peer ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
National Academy Of Medicine
The National Academy of Medicine (NAM), formerly called the Institute of Medicine (IoM) until 2015, is an American nonprofit, non-governmental organization. The National Academy of Medicine is a part of the National Academies of Sciences, Engineering, and Medicine, along with the National Academy of Sciences (NAS), National Academy of Engineering (NAE), and the National Research Council (NRC). The National Academy of Medicine provides national and international advice on issues relating to health, medicine, health policy, and biomedical science. It aims to provide unbiased, evidence-based, and authoritative information and advice concerning health and science policy to policy-makers, professionals, leaders in every sector of society, and the public at large. Operating outside the framework of the U.S. federal government, it relies on a volunteer workforce of scientists and other experts, operating under a formal peer-review system. As a national academy, the organization ann ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Matriculation In South Africa
In South Africa, matriculation (or matric) is the final year of high school and the qualification received on graduating from high school, and the minimum university entrance requirements. The first formal examination was conducted in South Africa under the University of the Cape of Good Hope in 1858. In general usage, the school-leaving exams, which are government-administered, are known as the "matric exams"; by extension, students in the final year of high school (grade 12) are known as "matriculants" or, more commonly, "matrics". Once the Matric year has been passed, students are said to have "matriculated". See . Qualification Officially, the qualification obtained at the end of secondary schooling is the National Senior Certificate, and the school-leaving examinations are the "Senior Certificate Examinations". The National Senior Certificate can be completed through either the Department of Education or the Independent Examination Board. Students who fulfill certain requireme ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Transkei
Transkei (, meaning ''the area beyond he riverKei''), officially the Republic of Transkei ( xh, iRiphabliki yeTranskei), was an unrecognised state in the southeastern region of South Africa from 1976 to 1994. It was, along with Ciskei, a Bantustan for the Xhosa people—and operated as a nominally independent parliamentary democracy. Its capital was Umtata (renamed Mthatha in 2004). Transkei represented a significant precedent and historic turning point in South Africa's policy of apartheid and "separate development"; it was the first of four territories to be declared independent of South Africa. Throughout its existence, it remained an internationally unrecognised, diplomatically isolated, politically unstable ''de facto'' one-party state, which at one point broke relations with South Africa, the only country that acknowledged it as a legal entity. In 1994, it was reintegrated into its larger neighbour and became part of the Eastern Cape province. History Establishment T ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Academy Of Science Of South Africa
The Academy of Science of South Africa (ASSAf) is the national science academy in South Africa. It was started in 1996, and encompasses all fields of scientific work. Its legal foundation is the ''Academy of Science of South Africa Act'', Act 67 of 2001, which came into operation in May 2002. The ASSAf was inaugurated in March 1996 by the former President of South Africa and patron of the academy, Nelson Mandela. In 2021, the academy had 632 members. History For about one century, the national science 'academy' comprised two separate institutions – the Royal Society (from the UK) and the ''Suid-Afrikaanse Akademie vir Wetenskap en Kuns'' (SAAWK). SAAWK had an Afrikaans-language focus and was heavily supported by South African business. Based in Pretoria, it was established in 1909 and was the national academy (the statute was passed in 1950) until democracy in 1994. It was structured in two 'faculties': human and natural sciences, with a journal for each. While it still a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cardiomyopathy
Cardiomyopathy is a group of diseases that affect the heart muscle. Early on there may be few or no symptoms. As the disease worsens, shortness of breath, feeling tired, and swelling of the legs may occur, due to the onset of heart failure. An irregular heart beat and fainting may occur. Those affected are at an increased risk of sudden cardiac death. Types of cardiomyopathy include hypertrophic cardiomyopathy, dilated cardiomyopathy, restrictive cardiomyopathy, arrhythmogenic right ventricular dysplasia, and Takotsubo cardiomyopathy (broken heart syndrome). In hypertrophic cardiomyopathy the heart muscle enlarges and thickens. In dilated cardiomyopathy the ventricles enlarge and weaken. In restrictive cardiomyopathy the ventricle stiffens. In many cases, the cause cannot be determined. Hypertrophic cardiomyopathy is usually inherited, whereas dilated cardiomyopathy is inherited in about one third of cases. Dilated cardiomyopathy may also result from alcohol, heavy m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tuberculous Pericarditis
Tuberculous pericarditis is a form of pericarditis. Pericarditis caused by tuberculosis is difficult to diagnose, because definitive diagnosis requires culturing '' Mycobacterium tuberculosis'' from aspirated pericardial fluid or pericardial biopsy, which requires high technical skill and is often not diagnostic (the yield from culture is low even with optimum specimens). The Tygerberg scoring system helps the clinician to decide whether pericarditis is due to tuberculosis or whether it is due to another cause: night sweats (1 point), weight loss (1 point), fever (2 point), serum globulin > 40g/L (3 points), blood total leucocyte count <10 x 109/l (3 points); a total score of 6 or more is highly suggestive of tuberculous pericarditis. Pericardial fluid with an interferon-γ level greater than 50 pg/mL is highly specific for tuberculous pericarditis. There are no randomized trials which evaluate the length of anti-tuberculosis treatment required for tuberculous pericardi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
