BioFET
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BioFET
A field-effect transistor-based biosensor, also known as a biosensor field-effect transistor (Bio-FET or BioFET), field-effect biosensor (FEB), or biosensor MOSFET, is a field-effect transistor (based on the MOSFET structure) that is gated by changes in the surface potential induced by the binding of molecules. When charged molecules, such as biomolecules, bind to the FET gate, which is usually a dielectric material, they can change the charge distribution of the underlying semiconductor material resulting in a change in conductance of the FET channel. A Bio-FET consists of two main compartments: one is the biological recognition element and the other is the field-effect transistor. The BioFET structure is largely based on the ion-sensitive field-effect transistor (ISFET), a type of metal-oxide-semiconductor field-effect transistor (MOSFET) where the metal gate is replaced by an ion-sensitive membrane, electrolyte solution and reference electrode. Mechanism of operation Bio-FETs c ...
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BioFET
A field-effect transistor-based biosensor, also known as a biosensor field-effect transistor (Bio-FET or BioFET), field-effect biosensor (FEB), or biosensor MOSFET, is a field-effect transistor (based on the MOSFET structure) that is gated by changes in the surface potential induced by the binding of molecules. When charged molecules, such as biomolecules, bind to the FET gate, which is usually a dielectric material, they can change the charge distribution of the underlying semiconductor material resulting in a change in conductance of the FET channel. A Bio-FET consists of two main compartments: one is the biological recognition element and the other is the field-effect transistor. The BioFET structure is largely based on the ion-sensitive field-effect transistor (ISFET), a type of metal-oxide-semiconductor field-effect transistor (MOSFET) where the metal gate is replaced by an ion-sensitive membrane, electrolyte solution and reference electrode. Mechanism of operation Bio-FETs c ...
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Biosensor
A biosensor is an analytical device, used for the detection of a chemical substance, that combines a biological component with a physicochemical detector. The ''sensitive biological element'', e.g. tissue, microorganisms, organelles, cell receptors, enzymes, antibodies, nucleic acids, etc., is a biologically derived material or biomimetic component that interacts with, binds with, or recognizes the analyte under study. The biologically sensitive elements can also be created by biological engineering. The ''transducer'' or the ''detector element'', which transforms one signal into another one, works in a physicochemical way: optical, piezoelectric, electrochemical, electrochemiluminescence etc., resulting from the interaction of the analyte with the biological element, to easily measure and quantify. The biosensor reader device connects with the associated electronics or signal processors that are primarily responsible for the display of the results in a user-friendly way. This ...
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Ion-sensitive Field-effect Transistor
An ion-sensitive field-effect transistor (ISFET) is a field-effect transistor used for measuring ion concentrations in solution; when the ion concentration (such as H+, see pH scale) changes, the current through the transistor will change accordingly. Here, the solution is used as the gate electrode. A voltage between substrate and oxide surfaces arises due to an ion sheath. It is a special type of MOSFET (metal-oxide-semiconductor field-effect transistor), and shares the same basic structure, but with the metal gate replaced by an ion-sensitive membrane, electrolyte solution and reference electrode. Invented in 1970, the ISFET was the first biosensor FET (BioFET). The surface hydrolysis of Si–OH groups of the gate materials varies in aqueous solutions due to pH value. Typical gate materials are SiO2, Si3N4, Al2O3 and Ta2O5. The mechanism responsible for the oxide surface charge can be described by the ''site binding model'', which describes the equilibrium between the ...
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Field-effect Transistor
The field-effect transistor (FET) is a type of transistor that uses an electric field to control the flow of current in a semiconductor. FETs (JFETs or MOSFETs) are devices with three terminals: ''source'', ''gate'', and ''drain''. FETs control the flow of current by the application of a voltage to the gate, which in turn alters the conductivity between the drain and source. FETs are also known as unipolar transistors since they involve single-carrier-type operation. That is, FETs use either electrons (n-channel) or holes (p-channel) as charge carriers in their operation, but not both. Many different types of field effect transistors exist. Field effect transistors generally display very high input impedance at low frequencies. The most widely used field-effect transistor is the MOSFET (metal-oxide-semiconductor field-effect transistor). History The concept of a field-effect transistor (FET) was first patented by Austro-Hungarian physicist Julius Edgar Lilienfeld in 192 ...
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Glass Electrode
A glass electrode is a type of ion-selective electrode made of a doped glass membrane that is sensitive to a specific ion. The most common application of ion-selective glass electrodes is for the measurement of pH. The pH electrode is an example of a glass electrode that is sensitive to hydrogen ions. Glass electrodes play an important part in the instrumentation for chemical analysis and physicochemical studies. The voltage of the glass electrode, relative to some reference value, is sensitive to changes in the activity of a certain type of ions. History The first studies of glass electrodes (GE) found different sensitivities of different glasses to change the medium's acidity (pH), due to the effects of the alkali metal ions. In 1906, M. Cremer, the father of Erika Cremer, determined that the electric potential that arises between parts of the fluid, located on opposite sides of the glass membrane is proportional to the concentration of acid (hydrogen ion concentration ...
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Leland C
Leland may refer to: Places United States * Leland, Illinois, a village * Leland, Iowa, a city * Leland, Michigan, an unincorporated community and census-designated place * Leland, Mississippi, a city * Leland, North Carolina, a town * Leland, Oregon, an unincorporated community * Leland, Utah, an unincorporated community * Leland, Washington, an unincorporated community * Leland, Wisconsin, an unincorporated community * Leland Township, Michigan * Leland River, Michigan * Leland Pond, New York Elsewhere * Leland, Norway, a village * Mount Leland, Victoria Land, Antarctica People Given name * Leland Austin (born 1986), American rapper under the stage name Yung L.A. * Leland Bardwell (1922–2016), Irish poet, novelist and playwright * Leland Chapman (born 1976), American bounty hunter on the reality television series ''Dog the Bounty Hunter'' * Leland Christensen (1959–2022), American politician * Leland D. Melvin (born 1964), American engineer and retired astronaut * Leland ...
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Computer History Museum
The Computer History Museum (CHM) is a museum of computer history, located in Mountain View, California. The museum presents stories and artifacts of Silicon Valley and the information age, and explores the computing revolution and its impact on society. History The museum's origins date to 1968 when Gordon Bell began a quest for a historical collection and, at that same time, others were looking to preserve the Whirlwind computer. The resulting ''Museum Project'' had its first exhibit in 1975, located in a converted coat closet in a DEC lobby. In 1978, the museum, now ''The Digital Computer Museum'' (TDCM), moved to a larger DEC lobby in Marlborough, Massachusetts. Maurice Wilkes presented the first lecture at TDCM in 1979 – the presentation of such lectures has continued to the present time. TDCM incorporated as '' The Computer Museum'' (TCM) in 1982. In 1984, TCM moved to Boston, locating on Museum Wharf. In 1996/1997, the TCM History Center (TCMHC) was established; a ...
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Dawon Kahng
Dawon Kahng ( ko, 강대원; May 4, 1931 – May 13, 1992) was a Korean-American electrical engineer and inventor, known for his work in solid-state electronics. He is best known for inventing the MOSFET (metal–oxide–semiconductor field-effect transistor, or MOS transistor), along with his colleague Mohamed Atalla, in 1959. Kahng and Atalla developed both the PMOS and NMOS processes for MOSFET semiconductor device fabrication. The MOSFET is the most widely used type of transistor, and the basic element in most modern electronic equipment. Kahng and Atalla later proposed the concept of the MOS integrated circuit, and they did pioneering work on Schottky diodes and nanolayer-base transistors in the early 1960s. Kahng then invented the floating-gate MOSFET (FGMOS) with Simon Min Sze in 1967. Kahng and Sze proposed that FGMOS could be used as floating-gate memory cells for non-volatile memory (NVM) and reprogrammable read-only memory (ROM), which became the basis for EPROM ( ...
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Mohamed M
Muhammad was an Islamic prophet and a religious and political leader who preached and established Islam. Muhammad and variations may also refer to: *Muhammad (name), a given name and surname, and list of people with the name and its variations Persons with the name Muhammad and no other name *Muhammad (Bavandid ruler), 13th-century Iranian monarch *Muhammad V of Kelantan (born 1969), 15th Yang di-Pertuan Agong and Sultan of Kelantan *Mohammed VI of Morocco (born 1963), King of Morocco * Muhammed VII, Sultan of Granada (1370–1408) *Muhammad VII of Bornu of the Sayfawa dynasty (1731–1747) * Muhammed VIII, Sultan of Granada (1411–1431) * Mohammed VIII of Bornu of the Sayfawa dynasty (1811–1814) Places * Mohammad-e Olya, a village in Fars Province, Iran *Mohammad, Gachsaran, a village in Kohgiluyeh and Boyer-Ahmad Province, Iran *Mohammad, Kohgiluyeh, a village in Kohgiluyeh and Boyer-Ahmad Province, Iran *Mohammad, Sistan and Baluchestan, a village in Sistan and Baluchest ...
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Classification Of BioFET
Classification is a process related to categorization, the process in which ideas and objects are recognized, differentiated and understood. Classification is the grouping of related facts into classes. It may also refer to: Business, organizations, and economics * Classification of customers, for marketing (as in Master data management) or for profitability (e.g. by Activity-based costing) * Classified information, as in legal or government documentation * Job classification, as in job analysis * Standard Industrial Classification, economic activities Mathematics * Attribute-value system, a basic knowledge representation framework * Classification theorems in mathematics * Mathematical classification, grouping mathematical objects based on a property that all those objects share * Statistical classification, identifying to which of a set of categories a new observation belongs, on the basis of a training set of data Media * Classification (literature), a figure of speech li ...
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Microcontroller
A microcontroller (MCU for ''microcontroller unit'', often also MC, UC, or μC) is a small computer on a single VLSI integrated circuit (IC) chip. A microcontroller contains one or more CPUs (processor cores) along with memory and programmable input/output peripherals. Program memory in the form of ferroelectric RAM, NOR flash or OTP ROM is also often included on chip, as well as a small amount of RAM. Microcontrollers are designed for embedded applications, in contrast to the microprocessors used in personal computers or other general purpose applications consisting of various discrete chips. In modern terminology, a microcontroller is similar to, but less sophisticated than, a system on a chip (SoC). An SoC may connect the external microcontroller chips as the motherboard components, but an SoC usually integrates the advanced peripherals like graphics processing unit (GPU) and Wi-Fi interface controller as its internal microcontroller unit circuits. Microcontrollers are use ...
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Signal Processing
Signal processing is an electrical engineering subfield that focuses on analyzing, modifying and synthesizing ''signals'', such as audio signal processing, sound, image processing, images, and scientific measurements. Signal processing techniques are used to optimize transmissions, Data storage, digital storage efficiency, correcting distorted signals, subjective video quality and to also detect or pinpoint components of interest in a measured signal. History According to Alan V. Oppenheim and Ronald W. Schafer, the principles of signal processing can be found in the classical numerical analysis techniques of the 17th century. They further state that the digital refinement of these techniques can be found in the digital control systems of the 1940s and 1950s. In 1948, Claude Shannon wrote the influential paper "A Mathematical Theory of Communication" which was published in the Bell System Technical Journal. The paper laid the groundwork for later development of information c ...
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