Biflavonoid
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Biflavonoid
Biflavonoids are a type of flavonoids with the general formula scheme (C6-C3-C6)2. Examples * Amentoflavone (bis-apigenin coupled at 8 and 3' positions) * Lophirone L and lophirone M found in ''Lophira alata'' * Sulcatone A, a naturally occurring biflavonoid isolated from '' Ouratea sulcata''. Extracts of the leaves of this plant, used with and with other plant's extracts, are used in many African countries to treat some infections such as upper tract respiratory infections, dysenteria, diarrhoea and toothache. Positive antimicrobial activity has been shown in-vitro against '' Staphylococcus aureus'' and ''Bacillus subtilis''. ''Escherichia coli'' showed to be resistant in the same study. * Hinokiflavone, a cytotoxic biflavonoid from ''Toxicodendron succedaneum'', ''Juniperus sp.'', or '' Chamaecyparis obtusa'' (hinoki). * Leaflets of ''Cycas circinalis'' and '' C. revoluta'' contain biflavonoids such as (2''S'', 2′′''S'')-2,3,2′′,3′′-tetrahydro-4′,4′′′-di- ...
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Ochnaflavone
Ochnaflavone, a secondary plant secondary metabolite of the Biflavonoid family, has been widely investigated in past decades due to its unique ability to mediate biological activities, such as inhibition of phospholipase A2 and lymphocyte proliferation. It was first isolated from '' Ochna squarrosa'' Linn, a member of Ochnaceae family, in 1973. Synthesis The first total synthesis of ochnaflavone derivatives was achieved by Kawano group in 1973, followed by the Heerden group for the first time reporting the total synthesis the ochnaflavone by constructing a diaryl ether intermediate and assemble the two flavone nuclei through ring cyclization. To date, the field of biochemistry of biflavonoids is still wide open. Little is known about Ochnaflavone of its natural occurrence and biosynthesis. Activity Although Ochnaflavone has not been fully studied in the past decades, its protective role in plants and human body already attract scientists’ much attention, such as anti-atherogen ...
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Cycas Circinalis
''Cycas circinalis'', also known as the queen sago, is a species of cycad known in the wild only from southern India. ''Cycas circinalis'' is the only gymnosperm species found among native Sri Lankan flora. Taxonomy ''C. circinallis'' is native to southern India and Sri Lanka, but the species name was formerly widely used for similar cycads in Southeast Asia, which leads to confusion in modern sources. The specimens described as "''C. circinallis''" in Indonesia and New Guinea is now recognized as ''Cycas rumphii''; while the taxon formerly described as the subspecies ''C. circinallis'' ssp. ''riuminiana'' from the Philippines is now regarded as a separate species, '' Cycas riuminiana''. Cultivation The plant is widely cultivated in Hawaii, both for its appearance in landscape and interiors, and for cut foliage. File:Cycas circinalis - sago palm - desc-top of trunk.jpg, Male cone, new File:Cycas circinalis 002.JPG, Male cone, old File:Cycas circinalis at Kadavoor.jpg, Young s ...
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Amentoflavone
Amentoflavone is a biflavonoid (''bis''-apigenin coupled at 8 and 3' positions, or 3′,8′′-biapigenin) constituent of a number of plants including ''Ginkgo biloba'', ''Chamaecyparis obtusa'' (hinoki), ''Hypericum perforatum'' (St. John's Wort) and ''Xerophyta plicata''. Amentoflavone can interact with many medications by being a potent inhibitor of CYP3A4 and CYP2C9, which are enzymes responsible for the metabolism of some drugs in the body. It is also an inhibitor of human cathepsin B. Amentoflavone has a variety of ''in vitro'' activities including antimalarial activity, anticancer activity (which may, at least in part, be mediated by its inhibition of fatty acid synthase), and antagonist activity at the κ-opioid receptor (''K''e = 490  nmol L−1) as well as activity at the allosteric In biochemistry, allosteric regulation (or allosteric control) is the regulation of an enzyme by binding an effector molecule at a site other than ...
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Cycas Revoluta
''Cycas revoluta'' (Sotetsu apanese ソテツ sago palm, king sago, sago cycad, Japanese sago palm) is a species of gymnosperm in the family Cycadaceae, native to southern Japan including the Ryukyu Islands. It is one of several species used for the production of sago, as well as an ornamental plant. The sago cycad can be distinguished by a thick coat of fibers on its trunk. The sago cycad is sometimes mistakenly thought to be a palm, although the only similarity between the two is that they look similar and both produce seeds. The leaves grow from the trunk and start out as small leaves near the centre of the plant. Names Cycads' only relations to the true palms (Arecaceae) is that both are vascular plants and seed plants. The Latin specific epithet ''revoluta'' means "curled back", in reference to the leaves. This is also called kungi (comb) palm in Urdu speaking areas. Description This very symmetrical plant supports a crown of shiny, dark green leaves on a thick shaggy t ...
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Morelloflavone
Morelloflavone, an isolate of ''Garcinia dulcis'', belongs to the family of biflavonoid Biflavonoids are a type of flavonoids with the general formula scheme (C6-C3-C6)2. Examples * Amentoflavone (bis-apigenin coupled at 8 and 3' positions) * Lophirone L and lophirone M found in ''Lophira alata'' * Sulcatone A, a naturally occur ...s and is an inhibitor of HMG-CoA reductase. References Flavonoids {{organic-compound-stub ...
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