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Baramicin
''Baramicin'' (''Bara'') is an antimicrobial peptide gene of the fruit fly '' Drosophila melanogaster''. Baramicin is a prominent element of the fly immune response: of the most abundant immune peptides detected in the fly hemolymph, the BaraA' gene is responsible for 9 of the 24 peptides first described for their high concentrations after systemic infection. The name of the ''Baramicin'' gene was inspired by One Piece character “ Buggy" and derives from the Japanese expression "Bara Bara", an onomatopoeia for things breaking apart, in reference to the Baramicin precursor breaking into multiple sub-peptides. Activity The Baramicin A precursor protein can be broken into three distinct domains: the IM10-like, IM22, and IM24 domains. Five sub-peptides are produced by the BaraA precursor including one IM24 peptide, three IM10-like peptides, and one IM22 peptide. Immune response The ''Baramicin'' gene is part of the Toll pathway antifungal immune response. Flies lacking ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
One Piece
''One Piece'' (stylized in all caps) is a Japanese manga series written and illustrated by Eiichiro Oda. It has been serialized in Shueisha's ''shōnen'' manga magazine ''Weekly Shōnen Jump'' since July 1997, with its individual chapters compiled into 104 ''tankōbon'' volumes . The story follows the adventures of Monkey D. Luffy, a boy whose body gained the properties of rubber after unintentionally eating a Devil Fruit. With his pirate crew, the Straw Hat Pirates, Luffy explores the Grand Line in search of the deceased King of the Pirates Gol D. Roger's ultimate treasure known as the "One Piece" in order to become the next King of the Pirates. The manga spawned a media franchise, having been adapted into a festival film produced by Production I.G, and an anime series produced by Toei Animation, which began broadcasting in Japan in 1999. Additionally, Toei has developed fourteen animated feature films, one original video animation, and thirteen television specials. ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Antimicrobial Peptide
Antimicrobial peptides (AMPs), also called host defence peptides (HDPs) are part of the innate immune response found among all classes of life. Fundamental differences exist between prokaryotic and eukaryotic cells that may represent targets for antimicrobial peptides. These peptides are potent, broad spectrum antibiotics which demonstrate potential as novel therapeutic agents. Antimicrobial peptides have been demonstrated to kill Gram negative and Gram positive bacteria, enveloped viruses, fungi and even transformed or cancerous cells. Unlike the majority of conventional antibiotics it appears that antimicrobial peptides frequently destabilize biological membranes, can form transmembrane channels, and may also have the ability to enhance immunity by functioning as immunomodulators. Structure Antimicrobial peptides are a unique and diverse group of molecules, which are divided into subgroups on the basis of their amino acid composition and structure. Antimicrobial peptides are ge ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Drosophila Melanogaster
''Drosophila melanogaster'' is a species of fly (the taxonomic order Diptera) in the family Drosophilidae. The species is often referred to as the fruit fly or lesser fruit fly, or less commonly the "vinegar fly" or "pomace fly". Starting with Charles W. Woodworth's 1901 proposal of the use of this species as a model organism, ''D. melanogaster'' continues to be widely used for biological research in genetics, physiology, microbial pathogenesis, and life history evolution. As of 2017, five Nobel Prizes have been awarded to drosophilists for their work using the insect. ''D. melanogaster'' is typically used in research owing to its rapid life cycle, relatively simple genetics with only four pairs of chromosomes, and large number of offspring per generation. It was originally an African species, with all non-African lineages having a common origin. Its geographic range includes all continents, including islands. ''D. melanogaster'' is a common pest in homes, restaurants, and othe ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Hemolymph
Hemolymph, or haemolymph, is a fluid, analogous to the blood in vertebrates, that circulates in the interior of the arthropod (invertebrate) body, remaining in direct contact with the animal's tissues. It is composed of a fluid plasma in which hemolymph cells called hemocytes are suspended. In addition to hemocytes, the plasma also contains many chemicals. It is the major tissue type of the open circulatory system characteristic of arthropods (e.g. arachnids, crustaceans and insects). In addition, some non-arthropods such as molluscs possess a hemolymphatic circulatory system. Oxygen-transport systems were long thought unnecessary in insects, but ancestral and functional hemocyanin has been found in the hemolymph. Insect "blood" generally does not carry hemoglobin, although hemoglobin may be present in the tracheal system instead and play some role in respiration. Method of transport In the grasshopper, the closed portion of the system consists of tubular hearts and an aort ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Buggy (One Piece)
The '' One Piece'' manga features an extensive cast of characters created by Eiichiro Oda. The series takes place in a fictional universe where vast numbers of pirates, soldiers, revolutionaries, and other adventurers fight each other, using various superhuman abilities. The majority of the characters are human, but the cast also includes dwarfs, giants, mermen and mermaids, fishmen, sky people, and minks, and many others. Many of the characters possess abilities gained by eating "Devil Fruits". The series' storyline follows the adventures of a group of pirates as they search for the mythical "One Piece" treasure. Monkey D. Luffy is the series' main protagonist, a young pirate who wishes to succeed Gol D. Roger, the deceased King of the Pirates, by finding his treasure, the "One Piece". Throughout the series, Luffy gathers himself a diverse crew, named the Straw Hat Pirates, including: the three-sword-wielding combatant Roronoa Zoro (sometimes referred to as Roronoa Zolo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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