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Baramicin
''Baramicin'' (''Bara'') is an antimicrobial peptide gene of the fruit fly ''Drosophila melanogaster''. Baramicin is a prominent element of the fly immune response: of the most abundant immune peptides detected in the fly hemolymph, the BaraA' gene is responsible for 9 of the 24 peptides first described for their high concentrations after systemic infection. The name of the ''Baramicin'' gene was inspired by One Piece character “ Buggy" and derives from the Japanese expression "Bara Bara", an onomatopoeia Onomatopoeia is the process of creating a word that phonetically imitates, resembles, or suggests the sound that it describes. Such a word itself is also called an onomatopoeia. Common onomatopoeias include animal noises such as ''oink'', '' ... for things breaking apart, in reference to the Baramicin precursor breaking into multiple sub-peptides. Activity The Baramicin A precursor protein can be broken into three distinct domains: the IM10-like, IM22, and IM24 doma ...
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One Piece
''One Piece'' (stylized in all caps) is a Japanese manga series written and illustrated by Eiichiro Oda. It has been serialized in Shueisha's ''shōnen'' manga magazine ''Weekly Shōnen Jump'' since July 1997, with its individual chapters compiled into 104 ''tankōbon'' volumes . The story follows the adventures of Monkey D. Luffy, a boy whose body gained the properties of rubber after unintentionally eating a Devil Fruit. With his pirate crew, the Straw Hat Pirates, Luffy explores the Grand Line in search of the deceased King of the Pirates Gol D. Roger's ultimate treasure known as the "One Piece" in order to become the next King of the Pirates. The manga spawned a media franchise, having been adapted into a festival film produced by Production I.G, and an anime series produced by Toei Animation, which began broadcasting in Japan in 1999. Additionally, Toei has developed fourteen animated feature films, one original video animation, and thirteen television specials. ...
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Antimicrobial Peptide
Antimicrobial peptides (AMPs), also called host defence peptides (HDPs) are part of the innate immune response found among all classes of life. Fundamental differences exist between prokaryotic and eukaryotic cells that may represent targets for antimicrobial peptides. These peptides are potent, broad spectrum antibiotics which demonstrate potential as novel therapeutic agents. Antimicrobial peptides have been demonstrated to kill Gram negative and Gram positive bacteria, enveloped viruses, fungi and even transformed or cancerous cells. Unlike the majority of conventional antibiotics it appears that antimicrobial peptides frequently destabilize biological membranes, can form transmembrane channels, and may also have the ability to enhance immunity by functioning as immunomodulators. Structure Antimicrobial peptides are a unique and diverse group of molecules, which are divided into subgroups on the basis of their amino acid composition and structure. Antimicrobial peptides are ge ...
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Drosophila Melanogaster
''Drosophila melanogaster'' is a species of fly (the taxonomic order Diptera) in the family Drosophilidae. The species is often referred to as the fruit fly or lesser fruit fly, or less commonly the "vinegar fly" or "pomace fly". Starting with Charles W. Woodworth's 1901 proposal of the use of this species as a model organism, ''D. melanogaster'' continues to be widely used for biological research in genetics, physiology, microbial pathogenesis, and life history evolution. As of 2017, five Nobel Prizes have been awarded to drosophilists for their work using the insect. ''D. melanogaster'' is typically used in research owing to its rapid life cycle, relatively simple genetics with only four pairs of chromosomes, and large number of offspring per generation. It was originally an African species, with all non-African lineages having a common origin. Its geographic range includes all continents, including islands. ''D. melanogaster'' is a common pest in homes, restaurants, and othe ...
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Hemolymph
Hemolymph, or haemolymph, is a fluid, analogous to the blood in vertebrates, that circulates in the interior of the arthropod (invertebrate) body, remaining in direct contact with the animal's tissues. It is composed of a fluid plasma in which hemolymph cells called hemocytes are suspended. In addition to hemocytes, the plasma also contains many chemicals. It is the major tissue type of the open circulatory system characteristic of arthropods (e.g. arachnids, crustaceans and insects). In addition, some non-arthropods such as molluscs possess a hemolymphatic circulatory system. Oxygen-transport systems were long thought unnecessary in insects, but ancestral and functional hemocyanin has been found in the hemolymph. Insect "blood" generally does not carry hemoglobin, although hemoglobin may be present in the tracheal system instead and play some role in respiration. Method of transport In the grasshopper, the closed portion of the system consists of tubular hearts and an aort ...
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Buggy (One Piece)
The ''One Piece'' manga features an extensive cast of characters created by Eiichiro Oda. The series takes place in a fictional universe where vast numbers of pirates, soldiers, revolutionaries, and other adventurers fight each other, using various superhuman abilities. The majority of the characters are human, but the cast also includes dwarfs, giants, mermen and mermaids, fishmen, sky people, and minks, and many others. Many of the characters possess abilities gained by eating "Devil Fruits". The series' storyline follows the adventures of a group of pirates as they search for the mythical "One Piece" treasure. Monkey D. Luffy is the series' main protagonist, a young pirate who wishes to succeed Gol D. Roger, the deceased King of the Pirates, by finding his treasure, the "One Piece". Throughout the series, Luffy gathers himself a diverse crew, named the Straw Hat Pirates, including: the three-sword-wielding combatant Roronoa Zoro (sometimes referred to as Roronoa Zolo in ...
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Onomatopoeia
Onomatopoeia is the process of creating a word that phonetically imitates, resembles, or suggests the sound that it describes. Such a word itself is also called an onomatopoeia. Common onomatopoeias include animal noises such as ''oink'', ''meow'' (or ''miaow''), ''roar'', and ''chirp''. Onomatopoeia can differ between languages: it conforms to some extent to the broader linguistic system; hence the sound of a clock may be expressed as ''tick tock'' in English, in Spanish and Italian (shown in the picture), in Mandarin, in Japanese, or in Hindi. The English term comes from the Ancient Greek compound ''onomatopoeia'', 'name-making', composed of ''onomato''- 'name' and -''poeia'' 'making'. Thus, words that imitate sounds can be said to be onomatopoeic or onomatopoetic. Uses In the case of a frog croaking, the spelling may vary because different frog species around the world make different sounds: Ancient Greek (only in Aristophanes' comic play ''The Frogs'') probably ...
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Toll-like Receptor
Toll-like receptors (TLRs) are a class of proteins that play a key role in the innate immune system. They are Bitopic protein, single-pass membrane-spanning Receptor (biochemistry), receptors usually expressed on sentinel cells such as macrophages and dendritic cells, that recognize structurally conserved molecules derived from microbes. Once these microbes have reached physical barriers such as the skin or intestinal tract mucosa, they are recognized by TLRs, which activate immune cell responses. The TLRs include TLR1, TLR2, TLR3, TLR4, TLR5, TLR6, TLR7, TLR8, TLR9, TLR10, TLR11, TLR12, and TLR13. Humans lack genes for TLR11, TLR12 and TLR13 and mice lack a functional gene for TLR10. TLR1, TLR2, TLR4, TLR5, TLR6, and TLR10 are located on the cell membrane, whereas TLR3, TLR7, TLR8, and TLR9 are located in Intracellular receptor, intracellular Vesicle (biology and chemistry), vesicles (because they are sensors of nucleic acids). TLRs received their name from their similarity to th ...
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Beauveria Bassiana
''Beauveria bassiana'' is a fungus that grows naturally in soils throughout the world and acts as a parasite on various arthropod species, causing white muscardine disease; it thus belongs to the entomopathogenic fungi. It is used as a biological insecticide to control a number of pests, including termites, thrips, whiteflies, aphids and various beetles. Its use in the control of bedbugs and malaria-transmitting mosquitos is under investigation.Donald G. McNeil Jr.Fungus Fatal to Mosquito May Aid Global War on Malaria ''The New York Times'', 10 June 2005 Discovery and name The species is named after the Italian entomologist Agostino Bassi, who discovered it in 1835 as the cause of the muscardine disease which then led to carriers transmitting it by airborne means, and later the same year it was named ''Botrytis bassiana'' by Giuseppe Gabriel Balsamo-Crivelli. In 1911 Jean Beauverie did further study and the next year Jean Paul Vuillemin made it the type species of his new ''B ...
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Metarhizium Rileyi
''Metarhizium rileyi''Kepler, Humber, Bischoff, Rehner SA (2014) ''Mycologia'' 106(4): 824. is a species of entomopathogenic fungus in the family Clavicipitaceae The Clavicipitaceae are a family of fungi within the order Hypocreales. A 2008 estimate placed 43 genera in the family, but recent work has increased this number to 97. Phylogeny Molecular phylogenetic analysis of multigene DNA sequence data in ...; there is extensive literature under its synonym ''Nomuraea rileyi''. References External links * * Clavicipitaceae Hypocreales genera Biological pest control Fungi described in 1883 {{Hypocreales-stub ...
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Peptides
Peptides (, ) are short chains of amino acids linked by peptide bonds. Long chains of amino acids are called proteins. Chains of fewer than twenty amino acids are called oligopeptides, and include dipeptides, tripeptides, and tetrapeptides. A polypeptide is a longer, continuous, unbranched peptide chain. Hence, peptides fall under the broad chemical classes of biological polymers and oligomers, alongside nucleic acids, oligosaccharides, polysaccharides, and others. A polypeptide that contains more than approximately 50 amino acids is known as a protein. Proteins consist of one or more polypeptides arranged in a biologically functional way, often bound to ligands such as coenzymes and cofactors, or to another protein or other macromolecule such as DNA or RNA, or to complex macromolecular assemblies. Amino acids that have been incorporated into peptides are termed residues. A water molecule is released during formation of each amide bond.. All peptides except cyclic peptides ...
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