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Braingate
BrainGate is a brain implant system built and previously owned by Cyberkinetics, currently under development and in clinical trials, designed to help those who have lost control of their limbs, or other bodily functions, such as patients with amyotrophic lateral sclerosis (ALS) or spinal cord injury. The Braingate technology and related Cyberkinetic’s assets are now owned by privately held Braingate, Co. The sensor, which is implanted into the brain, monitors brain activity in the patient and converts the intention of the user into computer commands. Technology In its current form, BrainGate consists of a sensor implanted in the brain and an external decoder device, which connects to some kind of prosthetic or other external object. The sensor is in the form of a microelectrode array, formerly known as the Utah Array, which consists of 100 hair-thin electrodes that sense the electromagnetic signature of neurons firing in specific areas of the brain, for example, the are ...
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BrainGate2-Drinking
BrainGate is a brain implant system built and previously owned by Cyberkinetics, currently under development and in clinical trials, designed to help those who have lost control of their Limb (anatomy), limbs, or other bodily functions, such as patients with amyotrophic lateral sclerosis (ALS) or spinal cord injury. The Braingate technology and related Cyberkinetic’s assets are now owned by privately held Braingate, Co. The sensor, which is implanted into the brain, monitors brain activity in the patient and converts the intention of the user into computer commands. Technology In its current form, BrainGate consists of a sensor implanted in the brain and an external decoder device, which connects to some kind of prosthetic or other external object. The sensor is in the form of a microelectrode array, formerly known as the Utah Array, which consists of 100 hair-thin electrodes that sense the electromagnetic signature of neurons firing in specific areas of the brain, for exampl ...
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BrainGate
BrainGate is a brain implant system built and previously owned by Cyberkinetics, currently under development and in clinical trials, designed to help those who have lost control of their limbs, or other bodily functions, such as patients with amyotrophic lateral sclerosis (ALS) or spinal cord injury. The Braingate technology and related Cyberkinetic’s assets are now owned by privately held Braingate, Co. The sensor, which is implanted into the brain, monitors brain activity in the patient and converts the intention of the user into computer commands. Technology In its current form, BrainGate consists of a sensor implanted in the brain and an external decoder device, which connects to some kind of prosthetic or other external object. The sensor is in the form of a microelectrode array, formerly known as the Utah Array, which consists of 100 hair-thin electrodes that sense the electromagnetic signature of neurons firing in specific areas of the brain, for example, the are ...
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Cyberkinetics
Cyberkinetics is an American company with roots tied to the University of Utah. It was co-founded by John Donoghue, Mijail Serruya, Gerhard Friehs of Brown University, and Nicho Hatsopoulos of the University of Chicago. The Braingate technology and related Cyberkinetic’s assets were acquired by BrainGate in 2008. BrainGate, Inc. is a privately held company designing and testing devices for transformative neurotechnologies which can help computers decode the neural signals to operate external devices.Braingate gets a new lease on life
The Boston Globe, August, 2009


Funding

Scientists behind the project used $9.3 million in first round funding led by
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Brain–computer Interface
A brain–computer interface (BCI), sometimes called a brain–machine interface (BMI) or smartbrain, is a direct communication pathway between the brain's electrical activity and an external device, most commonly a computer or robotic limb. BCIs are often directed at researching, mapping, assisting, augmenting, or repairing human cognitive or sensory-motor functions. Implementations of BCIs range from non-invasive ( EEG, MEG, EOG, MRI) and partially invasive (ECoG and endovascular) to invasive (microelectrode array), based on how close electrodes get to brain tissue.Michael L Martini, BA, Eric Karl Oermann, MD, Nicholas L Opie, PhD, Fedor Panov, MD, Thomas Oxley, MD, PhD, Kurt Yaeger, MD, Sensor Modalities for Brain-Computer Interface Technology: A Comprehensive Literature Review, Neurosurgery, Volume 86, Issue 2, February 2020, Pages E108–E117/ref> Research on BCIs began in the 1970s by Jacques Vidal at the University of California, Los Angeles (UCLA) under a grant from ...
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Brain Implant
Brain implants, often referred to as neural implants, are technological devices that connect directly to a biological subject's brain – usually placed on the surface of the brain, or attached to the brain's cortex. A common purpose of modern brain implants and the focus of much current research is establishing a biomedical prosthesis circumventing areas in the brain that have become dysfunctional after a stroke or other head injuries. This includes sensory substitution, e.g., in vision. Other brain implants are used in animal experiments simply to record brain activity for scientific reasons. Some brain implants involve creating interfaces between neural systems and computer chips. This work is part of a wider research field called brain–computer interfaces. (Brain–computer interface research also includes technology such as EEG arrays that allow interface between mind and machine but do not require direct implantation of a device.) Neural implants such as deep brain st ...
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Matt Nagle
Matthew Nagle (October 16, 1979 – July 24, 2007) was the first person to use a brain–computer interface to restore functionality lost due to paralysis. He was a C3 tetraplegic, paralyzed from the neck down after being stabbed. Biography Nagle attended Weymouth High School (Class of 1998). He was an exceptional athlete and a star football player. In 2001, he sustained a stabbing injury while leaving the town’s annual fireworks show near Wessagussett Beach on July 3. He was stabbed and his spinal cord severed when he stepped in to help a friend. Nagle died on July 24, 2007 in Stoughton, Massachusetts from sepsis. BrainGate Clinical Trial Nagle agreed to participate in a clinical trial involving the BrainGate Neural Interface System (developed by Cyberkinetics) out of a desire to again be healthy and lead a normal life, and in hopes that modern medical discoveries could help him. He also hoped that his participation in this Clinical Trial would help improve the lives of peo ...
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Microelectrode Array
Microelectrode arrays (MEAs) (also referred to as multielectrode arrays) are devices that contain multiple (tens to thousands) microelectrodes through which neural signals are obtained or delivered, essentially serving as neural interfaces that connect neurons to electronic circuitry. There are two general classes of MEAs: implantable MEAs, used ''in vivo'', and non-implantable MEAs, used ''in vitro''. Theory Neurons and muscle cells create ion currents through their membranes when excited, causing a change in voltage between the inside and the outside of the cell. When recording, the electrodes on an MEA transduce the change in voltage from the environment carried by ions into currents carried by electrons (electronic currents). When stimulating, electrodes transduce electronic currents into ionic currents through the media. This triggers the voltage-gated ion channels on the membranes of the excitable cells, causing the cell to depolarize and trigger an action potential if it ...
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Radcliffe Infirmary
The Radcliffe Infirmary was a hospital in central north Oxford, England, located at the southern end of Woodstock Road on the western side, backing onto Walton Street. History The initial proposals to build a hospital in Oxford were put forward at a meeting of the Radcliffe Trustees, who were administering John Radcliffe's estate valued at £4,000, in 1758. The facility was constructed on land given by Thomas Rowney, one of the two members of parliament for Oxford. The foundation stone was laid on 27 August 1761 and the new facility was officially opened on 18 October 1770. A fountain of the Greek god Triton was placed in front of the main infirmary building in 1858 and the Oxford Eye Hospital was established on the site in 1886.A brief history of the Nuffield Laboratory of Ophthalmology
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Kevin Warwick
Kevin Warwick (born 9 February 1954) is an English engineer and Deputy Vice-Chancellor (Research) at Coventry University. He is known for his studies on direct interfaces between computer systems and the human nervous system, and has also done research concerning robotics. Biography Kevin Warwick was born in 1954 in Keresley, Coventry, England, and was raised in the nearby village of Ryton-on-Dunsmore, Warwickshire. His family attended a Methodist church but soon he began doubting the existence of God. He attended Lawrence Sheriff School in Rugby, Warwickshire, where he was a contemporary of actor Arthur Bostrom. He left school at the age of 16 to start an apprenticeship with British Telecom. In 1976, he was granted his first degree at Aston University, followed by a PhD degree and a research job at Imperial College London. He took up positions at Somerville College in Oxford, Newcastle University, the University of Warwick, and the University of Reading, before relocatin ...
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Peter Kyberd
Peter Kyberd is an academic specialising in engineering cybernetics. He is currently head of the School of Energy and Electronic Engineering at Portsmouth University and serves on the editorial board of the ''Journal of Prosthetics and Orthotics''. His main research activity has been the practical application of technology to rehabilitation and engineering in Orthopaedics. Education Kyberd has a first class degree from Durham University ( Hatfield College), where he completed the science stream of the General Studies course and graduated in 1982. He then earned a MSc in Electronic Engineering from Southampton University, followed by a PhD from the same institution for work on the digital control of a multifunction prosthetic hand. Career After spending the previous decade working at the Oxford Orthopaedic Engineering Centre (part of the Nuffield Orthopaedic Centre), Kyberd lectured in the Cybernetics Department of Reading University, where he was part of the team that perform ...
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Current Clinical Trials
Currents, Current or The Current may refer to: Science and technology * Current (fluid), the flow of a liquid or a gas ** Air current, a flow of air ** Ocean current, a current in the ocean *** Rip current, a kind of water current ** Current (stream), currents in rivers and streams ** Convection current, flow caused by unstable density variation due to temperature differences * Current (mathematics), geometrical current in differential topology * Conserved current, a field associated to a symmetry in field theory * Electric current, a flow of electric charge through a medium * Probability current, in quantum mechanics * IBM Current, an early personal information management program Arts and entertainment Music * ''Current'' (album), a 1982 album by Heatwave * ''Currents'' (Eisley album) * ''Currents'' (Tame Impala album) * "The Current" (song), by the Blue Man Group * "Currents", a song by Dashboard Confessional from ''Dusk and Summer'', 2006 * "Currents", a song by Drake f ...
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Amyotrophic Lateral Sclerosis
Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease (MND) or Lou Gehrig's disease, is a neurodegenerative disease that results in the progressive loss of motor neurons that control voluntary muscles. ALS is the most common type of motor neuron diseases. Early symptoms of ALS include stiff muscles, muscle twitches, and gradual increasing weakness and muscle wasting. ''Limb-onset ALS'' begins with weakness in the arms or legs, while ''bulbar-onset ALS'' begins with difficulty speaking or swallowing. Half of the people with ALS develop at least mild difficulties with thinking and behavior, and about 15% develop frontotemporal dementia. Most people experience pain. The affected muscles are responsible for chewing food, speaking, and walking. Motor neuron loss continues until the ability to eat, speak, move, and finally the ability to breathe is lost. ALS eventually causes paralysis and early death, usually from respiratory failure. Most cases of ALS ...
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