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Borrelia Lusitaniae
''Borrelia lusitaniae'' is a bacterium of the spirochete class of the genus'' Borrelia'', which has a diderm (double-membrane) envelope. It is a part of the ''Borrelia burgdorferi'' ''sensu lato'' genospecies and is a Gram-negative bacterium. ''B. lusitaniae'' is tick-borne; he type strain is PotiB2. It can be pathogenic, being involved in cases of Lyme borreliosis. A species of tick, ''Ixodes ricinus'', is the host of ''B. lusitaniae''. It is thought to have originated from Portugal and has since spread to parts of Europe and North Africa. Lizards of the family Lacertidae are now believed to be important reservoir hosts of this bacterium. Origin and distribution While ''B. lusitaniae'' is distributed throughout countries in Europe and North Africa, it is the sole species of the Lyme borreliosis group in southern Portugal. Lizards of the family Lacertidae are believed to be important reservoir hosts of ''B. lusitaniae''. They were first isolated in Portugal in 1993. These lizar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spirochete
A spirochaete () or spirochete is a member of the phylum Spirochaetota (), (synonym Spirochaetes) which contains distinctive diderm (double-membrane) gram-negative bacteria, most of which have long, helically coiled (corkscrew-shaped or spiraled, hence the name) cells. Spirochaetes are chemoheterotrophic in nature, with lengths between 3 and 500 μm and diameters around 0.09 to at least 3 μm. Spirochaetes are distinguished from other bacterial phyla by the location of their flagella, called endoflagella which are sometimes called ''axial filaments''. Endoflagella are anchored at each end (pole) of the bacterium within the periplasmic space (between the inner and outer membranes) where they project backwards to extend the length of the cell. These cause a twisting motion which allows the spirochaete to move about. When reproducing, a spirochaete will undergo asexual transverse binary fission. Most spirochaetes are free-living and anaerobic, but there are numero ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Parapatric
In parapatric speciation, two subpopulations of a species evolve reproductive isolation from one another while continuing to exchange genes. This mode of speciation has three distinguishing characteristics: 1) mating occurs non-randomly, 2) gene flow occurs unequally, and 3) populations exist in either continuous or discontinuous geographic ranges. This distribution pattern may be the result of unequal dispersal, incomplete geographical barriers, or divergent expressions of behavior, among other things. Parapatric speciation predicts that hybrid zones will often exist at the junction between the two populations. In biogeography, the terms parapatric and parapatry are often used to describe the relationship between organisms whose ranges do not significantly overlap but are immediately adjacent to each other; they do not occur together except in a narrow contact zone. Parapatry is a geographical distribution opposed to sympatry (same area) and allopatry or peripatry (two similar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Microbiology And Immunology
Microbiology () is the scientific study of microorganisms, those being unicellular (single cell), multicellular (cell colony), or acellular (lacking cells). Microbiology encompasses numerous sub-disciplines including virology, bacteriology, protistology, mycology, immunology, and parasitology. Eukaryotic microorganisms possess membrane-bound organelles and include fungi and protists, whereas prokaryotic organisms—all of which are microorganisms—are conventionally classified as lacking membrane-bound organelles and include Bacteria and Archaea. Microbiologists traditionally relied on culture, staining, and microscopy. However, less than 1% of the microorganisms present in common environments can be cultured in isolation using current means. Microbiologists often rely on molecular biology tools such as DNA sequence based identification, for example the 16S rRNA gene sequence used for bacteria identification. Viruses have been variably classified as organisms, as they have been ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Plasmid
A plasmid is a small, extrachromosomal DNA molecule within a cell that is physically separated from chromosomal DNA and can replicate independently. They are most commonly found as small circular, double-stranded DNA molecules in bacteria; however, plasmids are sometimes present in archaea and eukaryotic organisms. In nature, plasmids often carry genes that benefit the survival of the organism and confer selective advantage such as antibiotic resistance. While chromosomes are large and contain all the essential genetic information for living under normal conditions, plasmids are usually very small and contain only additional genes that may be useful in certain situations or conditions. Artificial plasmids are widely used as vectors in molecular cloning, serving to drive the replication of recombinant DNA sequences within host organisms. In the laboratory, plasmids may be introduced into a cell via transformation. Synthetic plasmids are available for procurement over the inter ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Serological
Serology is the scientific study of serum and other body fluids. In practice, the term usually refers to the diagnostic identification of antibodies in the serum. Such antibodies are typically formed in response to an infection (against a given microorganism), against other foreign proteins (in response, for example, to a mismatched blood transfusion), or to one's own proteins (in instances of autoimmune disease). In either case, the procedure is simple. Serological tests Serological tests are diagnostic methods that are used to identify antibodies and antigens in a patient's sample. Serological tests may be performed to diagnose infections and autoimmune illnesses, to check if a person has immunity to certain diseases, and in many other situations, such as determining an individual's blood type. Serological tests may also be used in forensic serology to investigate crime scene evidence. Several methods can be used to detect antibodies and antigens, including ELISA, agglutinati ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Lisbon
Lisbon (; pt, Lisboa ) is the capital and largest city of Portugal, with an estimated population of 544,851 within its administrative limits in an area of 100.05 km2. Grande Lisboa, Lisbon's urban area extends beyond the city's administrative limits with a population of around 2.7 million people, being the List of urban areas of the European Union, 11th-most populous urban area in the European Union.Demographia: World Urban Areas - demographia.com, 06.2021 About 3 million people live in the Lisbon metropolitan area, making it the third largest metropolitan area in the Iberian Peninsula, after Madrid and Barcelona. It represents approximately 27% of the country's population. [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mafra, Portugal
Mafra () is a city and a municipality in the district of Lisbon, on the west coast of Portugal, and part of the urban agglomeration of the Greater Lisbon subregion. The population in 2011 was 76,685, in an area of 291.66 km2. It is mostly known for the sumptuous Mafra National Palace inscribed as a UNESCO World Heritage Site. Built in the baroque style, the Mafra National Palace also inspired Portuguese Nobel Prize laureate José Saramago to write his novel ''Baltasar and Blimunda'' (Memorial do Convento). Other points of interest around the municipality include the Tapada Nacional de Mafra, an enclosed wildlife and game reserve, and Ericeira's World Surf Reserve, the second in the world. History The earliest archaeological remnants discovered in Mafra date to an early settlement of this region in the Neolithic period. In Seixosa, civil parish of Encarnação, in an area that was once a beach, there were archaeological remnants from the Paleolithic period, that indicate one ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Belarus
Belarus,, , ; alternatively and formerly known as Byelorussia (from Russian ). officially the Republic of Belarus,; rus, Республика Беларусь, Respublika Belarus. is a landlocked country in Eastern Europe. It is bordered by Russia to the east and northeast, Ukraine to the south, Poland to the west, and Lithuania and Latvia to the northwest. Covering an area of and with a population of 9.4 million, Belarus is the List of European countries by area, 13th-largest and the List of European countries by population, 20th-most populous country in Europe. The country has a hemiboreal climate and is administratively divided into Regions of Belarus, seven regions. Minsk is the capital and List of cities and largest towns in Belarus, largest city. Until the 20th century, different states at various times controlled the lands of modern-day Belarus, including Kievan Rus', the Principality of Polotsk, the Grand Duchy of Lithuania, the Polish–Lithuanian Commonwealth, and t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ukraine
Ukraine ( uk, Україна, Ukraïna, ) is a country in Eastern Europe. It is the second-largest European country after Russia, which it borders to the east and northeast. Ukraine covers approximately . Prior to the ongoing Russian invasion, it was the eighth-most populous country in Europe, with a population of around 41 million people. It is also bordered by Belarus to the north; by Poland, Slovakia, and Hungary to the west; and by Romania and Moldova to the southwest; with a coastline along the Black Sea and the Sea of Azov to the south and southeast. Kyiv is the nation's capital and largest city. Ukraine's state language is Ukrainian; Russian is also widely spoken, especially in the east and south. During the Middle Ages, Ukraine was the site of early Slavic expansion and the area later became a key centre of East Slavic culture under the state of Kievan Rus', which emerged in the 9th century. The state eventually disintegrated into rival regional po ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Moldavia
Moldavia ( ro, Moldova, or , literally "The Country of Moldavia"; in Romanian Cyrillic: or ; chu, Землѧ Молдавскаѧ; el, Ἡγεμονία τῆς Μολδαβίας) is a historical region and former principality in Central and Eastern Europe, corresponding to the territory between the Eastern Carpathians and the Dniester River. An initially independent and later autonomous state, it existed from the 14th century to 1859, when it united with Wallachia () as the basis of the modern Romanian state; at various times, Moldavia included the regions of Bessarabia (with the Budjak), all of Bukovina and Hertsa. The region of Pokuttya was also part of it for a period of time. The western half of Moldavia is now part of Romania, the eastern side belongs to the Republic of Moldova, and the northern and southeastern parts are territories of Ukraine. Name and etymology The original and short-lived reference to the region was ''Bogdania'', after Bogdan I, the fo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Czech Republic
The Czech Republic, or simply Czechia, is a landlocked country in Central Europe. Historically known as Bohemia, it is bordered by Austria to the south, Germany to the west, Poland to the northeast, and Slovakia to the southeast. The Czech Republic has a hilly landscape that covers an area of with a mostly temperate continental and oceanic climate. The capital and largest city is Prague; other major cities and urban areas include Brno, Ostrava, Plzeň and Liberec. The Duchy of Bohemia was founded in the late 9th century under Great Moravia. It was formally recognized as an Imperial State of the Holy Roman Empire in 1002 and became a kingdom in 1198. Following the Battle of Mohács in 1526, the whole Crown of Bohemia was gradually integrated into the Habsburg monarchy. The Protestant Bohemian Revolt led to the Thirty Years' War. After the Battle of White Mountain, the Habsburgs consolidated their rule. With the dissolution of the Holy Empire in 1806, the Cro ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Housekeeping Genes
In molecular biology, housekeeping genes are typically constitutive genes that are required for the maintenance of basic cellular function, and are expressed in all cells of an organism under normal and patho-physiological conditions. Although some housekeeping genes are expressed at relatively constant rates in most non-pathological situations, the expression of other housekeeping genes may vary depending on experimental conditions. The origin of the term "housekeeping gene" remains obscure. Literature from 1976 used the term to describe specifically tRNA and rRNA. For experimental purposes, the expression of one or multiple housekeeping genes is used as a reference point for the analysis of expression levels of other genes. The key criterion for the use of a housekeeping gene in this manner is that the chosen housekeeping gene is uniformly expressed with low variance under both control and experimental conditions. Validation of housekeeping genes should be performed before th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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