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Biostatistics Journals
Biostatistics (also known as biometry) are the development and application of statistical methods to a wide range of topics in biology. It encompasses the design of biological experiments, the collection and analysis of data from those experiments and the interpretation of the results. History Biostatistics and genetics Biostatistical modeling forms an important part of numerous modern biological theories. Genetics studies, since its beginning, used statistical concepts to understand observed experimental results. Some genetics scientists even contributed with statistical advances with the development of methods and tools. Gregor Mendel started the genetics studies investigating genetics segregation patterns in families of peas and used statistics to explain the collected data. In the early 1900s, after the rediscovery of Mendel's Mendelian inheritance work, there were gaps in understanding between genetics and evolutionary Darwinism. Francis Galton tried to expand Mendel's ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Statistical
Statistics (from German: ''Statistik'', "description of a state, a country") is the discipline that concerns the collection, organization, analysis, interpretation, and presentation of data. In applying statistics to a scientific, industrial, or social problem, it is conventional to begin with a statistical population or a statistical model to be studied. Populations can be diverse groups of people or objects such as "all people living in a country" or "every atom composing a crystal". Statistics deals with every aspect of data, including the planning of data collection in terms of the design of surveys and experiments.Dodge, Y. (2006) ''The Oxford Dictionary of Statistical Terms'', Oxford University Press. When census data cannot be collected, statisticians collect data by developing specific experiment designs and survey samples. Representative sampling assures that inferences and conclusions can reasonably extend from the sample to the population as a whole. An experim ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
The Genetical Theory Of Natural Selection
''The Genetical Theory of Natural Selection'' is a book by Ronald Fisher which combines Mendelian genetics with Charles Darwin's theory of natural selection, with Fisher being the first to argue that "Mendelism therefore validates Darwinism" and stating with regard to mutations that "The vast majority of large mutations are deleterious; small mutations are both far more frequent and more likely to be useful", thus refuting orthogenesis. First published in 1930 by The Clarendon Press, it is one of the most important books of the modern synthesis, and helped define population genetics. It is commonly cited in biology books, outlining many concepts that are still considered important such as Fisherian runaway, Fisher's principle, reproductive value, Fisher's fundamental theorem of natural selection, Fisher's geometric model, the sexy son hypothesis, mimicry and the evolution of dominance. It was dictated to his wife in the evenings as he worked at Rothamsted Research in the day. Co ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Qualitative Data
Qualitative properties are properties that are observed and can generally not be measured with a numerical result. They are contrasted to quantitative properties which have numerical characteristics. Some engineering and scientific properties are qualitative. A test method can result in qualitative data about something. This can be a categorical result or a binary classification Binary classification is the task of classifying the elements of a set into two groups (each called ''class'') on the basis of a classification rule. Typical binary classification problems include: * Medical testing to determine if a patient has c ... (e.g., pass/fail, go/no go, Conformity, conform/non-conform). It can sometimes be an engineering judgement. The data that all share a qualitative property form a nominal category. A variable which codes for the presence or absence of such a property is called a binary categorical variable, or equivalently a dummy variable (statistics), dummy variable. In b ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
D'Arcy Thompson
Sir D'Arcy Wentworth Thompson CB FRS FRSE (2 May 1860 – 21 June 1948) was a Scottish biologist, mathematician and classics scholar. He was a pioneer of mathematical and theoretical biology, travelled on expeditions to the Bering Strait and held the position of Professor of Natural History at University College, Dundee for 32 years, then at St Andrews for 31 years. He was elected a Fellow of the Royal Society, was knighted, and received the Darwin Medal and the Daniel Giraud Elliot Medal. Thompson is remembered as the author of the 1917 book ''On Growth and Form'', which led the way for the scientific explanation of morphogenesis, the process by which patterns and body structures are formed in plants and animals. Thompson's description of the mathematical beauty of nature, and the mathematical basis of the forms of animals and plants, stimulated thinkers as diverse as Julian Huxley, C. H. Waddington, Alan Turing, René Thom, Claude Lévi-Strauss, Eduardo Paolozzi, Le Corb ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Statistics
Statistics (from German language, German: ''wikt:Statistik#German, Statistik'', "description of a State (polity), state, a country") is the discipline that concerns the collection, organization, analysis, interpretation, and presentation of data. In applying statistics to a scientific, industrial, or social problem, it is conventional to begin with a statistical population or a statistical model to be studied. Populations can be diverse groups of people or objects such as "all people living in a country" or "every atom composing a crystal". Statistics deals with every aspect of data, including the planning of data collection in terms of the design of statistical survey, surveys and experimental design, experiments.Dodge, Y. (2006) ''The Oxford Dictionary of Statistical Terms'', Oxford University Press. When census data cannot be collected, statisticians collect data by developing specific experiment designs and survey sample (statistics), samples. Representative sampling as ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Genetics
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Evolutionary Biology
Evolutionary biology is the subfield of biology that studies the evolutionary processes (natural selection, common descent, speciation) that produced the diversity of life on Earth. It is also defined as the study of the history of life forms on Earth. Evolution is based on the theory that all species are related and they gradually change over time. In a population, the genetic variations affect the physical characteristics i.e. phenotypes of an organism. These changes in the phenotypes will be an advantage to some organisms, which will then be passed onto their offspring. Some examples of evolution in species over many generations are the Peppered Moth and Flightless birds. In the 1930s, the discipline of evolutionary biology emerged through what Julian Huxley called the modern synthesis of understanding, from previously unrelated fields of biological research, such as genetics and ecology, systematics, and paleontology. The importance of studying Evolutionary biology is ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Mathematical Biology
Mathematical and theoretical biology, or biomathematics, is a branch of biology which employs theoretical analysis, mathematical models and abstractions of the living organisms to investigate the principles that govern the structure, development and behavior of the systems, as opposed to experimental biology which deals with the conduction of experiments to prove and validate the scientific theories. The field is sometimes called mathematical biology or biomathematics to stress the mathematical side, or theoretical biology to stress the biological side. Theoretical biology focuses more on the development of theoretical principles for biology while mathematical biology focuses on the use of mathematical tools to study biological systems, even though the two terms are sometimes interchanged. Mathematical biology aims at the mathematical representation and modeling of biological processes, using techniques and tools of applied mathematics. It can be useful in both theoretical and prac ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Primordial Soup
Primordial soup, also known as, primordial goo, primordial ooze, prebiotic soup and prebiotic broth, is the hypothetical set of conditions present on the Earth around 3.7 to 4.0 billion years ago. It is an aspect of the heterotrophic theory (also known as the Oparin–Haldane hypothesis) concerning the origin of life, first proposed by Alexander Oparin in 1924, and J. B. S. Haldane in 1929. As formulated by Oparin, in the primitive Earth's surface layers, carbon, hydrogen, water vapour, and ammonia reacted to form the first organic compounds. The concept of a primordial soup gained credence in 1953 when the "Miller–Urey experiment" used a highly reduced mixture of gases—methane, ammonia and hydrogen—to form basic organic monomers, such as amino acids. Historical background The notion that living beings originated from inanimate materials comes from the Ancient Greeks—the theory known as spontaneous generation. Aristotle in the 4th century BCE gave a proper explanation, wri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Inbreeding Coefficient
The coefficient of inbreeding of an individual is the probability that two alleles at any locus in an individual are identical by descent from the common ancestor(s) of the two parents. The coefficient of inbreeding is: The probability that two alleles at a given locus are identical by descent. The coefficient of relationship is: The proportion Proportionality, proportion or proportional may refer to: Mathematics * Proportionality (mathematics), the property of two variables being in a multiplicative relation to a constant * Ratio, of one quantity to another, especially of a part compare ... of genes that are held in common by two individuals as a result of direct or collateral relationship. References Population genetics {{genetics-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
F-statistics
In population genetics, ''F''-statistics (also known as fixation indices) describe the statistically expected level of heterozygosity in a population; more specifically the expected degree of (usually) a reduction in heterozygosity when compared to Hardy–Weinberg expectation. ''F''-statistics can also be thought of as a measure of the correlation between genes drawn at different levels of a (hierarchically) subdivided population. This correlation is influenced by several evolutionary processes, such as genetic drift, founder effect, bottleneck, genetic hitchhiking, meiotic drive, mutation, gene flow, inbreeding, natural selection, or the Wahlund effect, but it was originally designed to measure the amount of allelic fixation owing to genetic drift. The concept of ''F''-statistics was developed during the 1920s by the American geneticist Sewall Wright, who was interested in inbreeding in cattle. However, because complete dominance causes the phenotypes of homozygote dominants ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Sewall G
Sewall is a surname. Notable people with the surname include: * Arthur Sewall (1835–1900), Shipbuilder and American Democratic politician from Maine * Charles S. Sewall (1779–1848), American politician * Doug Sewall, American wheelchair curler * George P. Sewall (1811–1881), American lawyer and State Representative from Old Town, Maine * Gilbert T. Sewall (born 1946), American educator and author * Harold M. Sewall (1860–1924), American politician and diplomat * Harriet Winslow Sewall (1819–1889), American poet * Jonathan Sewall (1729–1796), last British attorney general of Massachusetts * Joseph Sewall (1921–2011), American businessman and politician from Maine * May Wright Sewall (1844–1920), American feminist, educator, and lecturer * Richard B. Sewall (1908–2003), American professor of English at Yale University * Samuel Sewall (1652–1730), American judge in Massachusetts * Samuel Sewall (congressman) (1757–1814), American lawyer and congressman * ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
