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Biositemap ITools NCBC
A Biositemap is a way for a biomedical research institution of organisation to show how biological information is distributed throughout their Information Technology systems and networks. This information may be shared with other organisations and researchers. The Biositemap enables web browsers, crawlers and robots to easily access and process the information to use in other systems, media and computational formats. Biositemaps protocols provide clues for the Biositemap web harvesters, allowing them to find resources and content across the whole interlink of the Biositemap system. This means that human or machine users can access any relevant information on any topic across all organisations throughout the Biositemap system and bring it to their own systems for assimilation or analysis. File framework The information is normally stored in a biositemap.rdf or biositemap.xml file which contains lists of information about the data, software, tools material and services provided or ...
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Medical Research
Medical research (or biomedical research), also known as experimental medicine, encompasses a wide array of research, extending from " basic research" (also called ''bench science'' or ''bench research''), – involving fundamental scientific principles that may apply to a ''preclinical'' understanding – to clinical research, which involves studies of people who may be subjects in clinical trials. Within this spectrum is applied research, or translational research, conducted to expand knowledge in the field of medicine. Both clinical and preclinical research phases exist in the pharmaceutical industry's drug development pipelines, where the clinical phase is denoted by the term ''clinical trial''. However, only part of the clinical or preclinical research is oriented towards a specific pharmaceutical purpose. The need for fundamental and mechanism-based understanding, diagnostics, medical devices, and non-pharmaceutical therapies means that pharmaceutical research ...
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Formal Ontology
In philosophy, the term formal ontology is used to refer to an ontology defined by axioms in a formal language with the goal to provide an unbiased (domain- and application-independent) view on reality, which can help the modeler of domain- or application-specific ontologies (information science) to avoid possibly erroneous ontological assumptions encountered in modeling large-scale ontologies. By maintaining an independent view on reality a formal ( upper level) ontology gains the following properties: *indefinite expandability: *:the ontology remains consistent with increasing content. *content and context independence: *:any kind of 'concept' can find its place. *accommodate different levels of granularity. Historical background Theories on how to conceptualize reality date back as far as Plato and Aristotle. The term 'formal ontology' itself was coined by Edmund Husserl in the second edition of his '' Logical Investigations'' (1900–01), where it refers to an ontological ...
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Domain-specific Knowledge Representation Languages
Domain specificity is a theoretical position in cognitive science (especially modern cognitive development) that argues that many aspects of cognition are supported by specialized, presumably evolutionarily specified, learning devices. The position is a close relative of modularity of mind, but is considered more general in that it does not necessarily entail all the assumptions of Fodorian modularity (e.g., informational encapsulation). Instead, it is properly described as a variant of psychological nativism. Other cognitive scientists also hold the mind to be modular, without the modules necessarily possessing the characteristics of Fodorian modularity. Domain specificity emerged in the aftermath of the cognitive revolution as a theoretical alternative to empiricist theories that believed all learning can be driven by the operation of a few such general learning devices. Prominent examples of such domain-general views include Jean Piaget’s theory of cognitive development, ...
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Sitemaps
The Sitemaps protocol allows a webmaster to inform search engines about URLs on a website that are available for crawling. A Sitemap is an XML file that lists the URLs for a site. It allows webmasters to include additional information about each URL: when it was last updated, how often it changes, and how important it is in relation to other URLs of the site. This allows search engines to crawl the site more efficiently and to find URLs that may be isolated from the rest of the site's content. The Sitemaps protocol is a URL inclusion protocol and complements robots.txt, a URL exclusion protocol. History Google first introduced Sitemaps 0.84 in June 2005 so web developers could publish lists of links from across their sites. Google, Yahoo! and Microsoft announced joint support for the Sitemaps protocol in November 2006. The schema version was changed to "Sitemap 0.90", but no other changes were made. In April 2007, Ask.com and IBM announced support for Sitemaps. Also, Google ...
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ITools Resourceome
iTools{{cite journal, vauthors=Dinov ID, Rubin D, Lorensen W, Dugan J, Ma J, Murphy S, Kirschner B, Bug W, Sherman M, Floratos A, Kennedy D, Jagadish HV, Schmidt J, Athey B, Califano A, Musen M, Altman R, Kikinis R, Kohane I, Delp S, Parker DS, Toga AW , title=iTools: A Framework for Classification, Categorization and Integration of Computational Biology Resources , journal=PLOS ONE , volume=3, issue=5, pages= e2265, doi=10.1371/journal.pone.0002265 , year=2008 , pmid=18509477 , pmc=2386255, bibcode=2008PLoSO...3.2265D , doi-access=free is a distributed infrastructure for managing, discovery, comparison and integration of computational biology resources. iTools employs Biositemap technology to retrieve and service meta-data about diverse bioinformatics data services, tools, and web-services. iTools is developed by the National Centers for Biomedical Computing as part of thNIH Road Map Initiative See also * Biositemaps A Biositemap is a way for a biomedical research instit ...
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Information Visualization
Information is an abstract concept that refers to that which has the power to inform. At the most fundamental level information pertains to the interpretation of that which may be sensed. Any natural process that is not completely random, and any observable pattern in any medium can be said to convey some amount of information. Whereas digital signals and other data use discrete signs to convey information, other phenomena and artifacts such as analog signals, poems, pictures, music or other sounds, and currents convey information in a more continuous form. Information is not knowledge itself, but the meaning that may be derived from a representation through interpretation. Information is often processed iteratively: Data available at one step are processed into information to be interpreted and processed at the next step. For example, in written text each symbol or letter conveys information relevant to the word it is part of, each word conveys information releva ...
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Resource Description Framework
The Resource Description Framework (RDF) is a World Wide Web Consortium (W3C) standard originally designed as a data model for metadata. It has come to be used as a general method for description and exchange of graph data. RDF provides a variety of syntax notations and data serialization formats with Turtle (Terse RDF Triple Language) currently being the most widely used notation. RDF is a directed graph composed of triple statements. An RDF graph statement is represented by: 1) a node for the subject, 2) an arc that goes from a subject to an object for the predicate, and 3) a node for the object. Each of the three parts of the statement can be identified by a URI. An object can also be a literal value. This simple, flexible data model has a lot of expressive power to represent complex situations, relationships, and other things of interest, while also being appropriately abstract. RDF was adopted as a W3C recommendation in 1999. The RDF 1.0 specification was published in 2004, th ...
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Sitemaps
The Sitemaps protocol allows a webmaster to inform search engines about URLs on a website that are available for crawling. A Sitemap is an XML file that lists the URLs for a site. It allows webmasters to include additional information about each URL: when it was last updated, how often it changes, and how important it is in relation to other URLs of the site. This allows search engines to crawl the site more efficiently and to find URLs that may be isolated from the rest of the site's content. The Sitemaps protocol is a URL inclusion protocol and complements robots.txt, a URL exclusion protocol. History Google first introduced Sitemaps 0.84 in June 2005 so web developers could publish lists of links from across their sites. Google, Yahoo! and Microsoft announced joint support for the Sitemaps protocol in November 2006. The schema version was changed to "Sitemap 0.90", but no other changes were made. In April 2007, Ask.com and IBM announced support for Sitemaps. Also, Google ...
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Computational Biology
Computational biology refers to the use of data analysis, mathematical modeling and Computer simulation, computational simulations to understand biological systems and relationships. An intersection of computer science, biology, and big data, the field also has foundations in applied mathematics, chemistry, and genetics. It differs from biological computing, a subfield of computer engineering which uses bioengineering to build computers. History Bioinformatics, the analysis of informatics processes in biological systems, began in the early 1970s. At this time, research in artificial intelligence was using network models of the human brain in order to generate new algorithms. This use of biological data pushed biological researchers to use computers to evaluate and compare large data sets in their own field. By 1982, researchers shared information via Punched card, punch cards. The amount of data grew exponentially by the end of the 1980s, requiring new computational method ...
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Information Model
An information model in software engineering is a representation of concepts and the relationships, constraints, rules, and operations to specify data semantics for a chosen domain of discourse. Typically it specifies relations between kinds of things, but may also include relations with individual things. It can provide sharable, stable, and organized structure of information requirements or knowledge for the domain context.Y. Tina Lee (1999)"Information modeling from design to implementation"National Institute of Standards and Technology. Overview The term ''information model'' in general is used for models of individual things, such as facilities, buildings, process plants, etc. In those cases, the concept is specialised to facility information model, building information model, plant information model, etc. Such an information model is an integration of a model of the facility with the data and documents about the facility. Within the field of software engineering and data ...
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Information Technology
Information technology (IT) is the use of computers to create, process, store, retrieve, and exchange all kinds of Data (computing), data . and information. IT forms part of information and communications technology (ICT). An information technology system (IT system) is generally an information system, a communications system, or, more specifically speaking, a Computer, computer system — including all Computer hardware, hardware, software, and peripheral equipment — operated by a limited group of IT users. Although humans have been storing, retrieving, manipulating, and communicating information since the earliest writing systems were developed, the term ''information technology'' in its modern sense first appeared in a 1958 article published in the ''Harvard Business Review''; authors Harold Leavitt, Harold J. Leavitt and Thomas L. Whisler commented that "the new technology does not yet have a single established name. We shall call it information technology (IT)." Their ...
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Site Map
A sitemap is a list of pages of a web site within a domain. There are three primary kinds of sitemap: * Sitemaps used during the planning of a website by its designers. * Human-visible listings, typically hierarchical, of the pages on a site. * Structured listings intended for web crawlers such as search engines. Types of sitemaps Sitemaps may be addressed to users or to software. Many sites have user-visible sitemaps which present a systematic view, typically hierarchical, of the site. These are intended to help visitors find specific pages, and can also be used by crawlers. They also act as a navigation aid by providing an overview of a site's content at a single glance. Alphabetically organized sitemaps, sometimes called site indexes, are a different approach. For use by search engines and other crawlers, there is a structured format, the XML Sitemap, which lists the pages in a site, their relative importance, and how often they are updated. This is pointed to from the ...
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