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Big Five Weapons
{{Unreferenced, date=June 2019, bot=noref (GreenC bot) The Big Five was a series of biological weapons developed by the United States Army Chemical Corps' Special Operations Division (SOD) at Fort Detrick Biological Warfare Laboratory (BWL) for use by special forces. These weapons were developed in the 1950s and 1960s, and were eventually destroyed when the United States unilaterally ended its offensive biological warfare program. The weapons were - M1 Biodart (E1) A 7.62mm rifle cartridge with a sabot surrounding a flechette with exterior grooves filled with either botulinum toxin A (XR), saxitoxin (TZ), or possibly a combination of the two. There were 4,450 filled and 5,315 unfilled M1s in the arsenal at the time of its destruction. M2 Separable Bullet (E2) A 7.62mm rifle cartridge with a hollow metal bullet containing dry-type botulinum toxin A (XR), or a simulant. The bullet would release a puff of aerosol on impact. Anthrax (TR) was another possible fill. There were ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biological Weapons
A biological agent (also called bio-agent, biological threat agent, biological warfare agent, biological weapon, or bioweapon) is a bacterium, virus, protozoan, parasite, fungus, or toxin that can be used purposefully as a weapon in bioterrorism or biological warfare (BW). In addition to these living or replicating pathogens, toxins and biotoxins are also included among the bio-agents. More than 1,200 different kinds of potentially weaponizable bio-agents have been described and studied to date. Biological agents have the ability to adversely affect human health in a variety of ways, ranging from relatively mild allergic reactions to serious medical conditions, including serious injury, as well as serious or permanent disability or even death. Many of these organisms are ubiquitous in the natural environment where they are found in water, soil, plants, or animals. Bio-agents may be amenable to "weaponization" to render them easier to deploy or disseminate. Genetic modification m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States Army
The United States Army (USA) is the land service branch of the United States Armed Forces. It is one of the eight U.S. uniformed services, and is designated as the Army of the United States in the U.S. Constitution.Article II, section 2, clause 1 of the United States Constitution (1789). See alsTitle 10, Subtitle B, Chapter 301, Section 3001 The oldest and most senior branch of the U.S. military in order of precedence, the modern U.S. Army has its roots in the Continental Army, which was formed 14 June 1775 to fight the American Revolutionary War (1775–1783)—before the United States was established as a country. After the Revolutionary War, the Congress of the Confederation created the United States Army on 3 June 1784 to replace the disbanded Continental Army.Library of CongressJournals of the Continental Congress, Volume 27/ref> The United States Army considers itself to be a continuation of the Continental Army, and thus considers its institutional inception to be th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Chemical Corps
The Chemical Corps is the branch of the United States Army tasked with defending against chemical, biological, radiological, and nuclear (CBRN) weapons. The Chemical Warfare Service was established on 28 June 1918, combining activities that until then had been dispersed among five separate agencies of the United States federal government. It was made a permanent branch of the Regular Army by the National Defense Act of 1920. In 1945, it was redesignated the Chemical Corps. History Origins Discussion of the topic dates back to the American Civil War. A letter to the War Department dated 5 April 1862 from New York City resident John Doughty proposed the use of chlorine shells to drive the Confederate Army from its positions. Doughty included a detailed drawing of the shell with his letter. It is unknown how the military reacted to Doughty's proposal but the letter was unnoticed in a pile of old official documents until modern times. Another American, Forrest Shepherd, also propos ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fort Detrick
Fort Detrick () is a United States Army Futures Command installation located in Frederick, Maryland. Historically, Fort Detrick was the center of the U.S. biological weapons program from 1943 to 1969. Since the discontinuation of that program, it has hosted most elements of the United States biological defense program. As of the early 2010s, Fort Detrick's campus supports a multi-governmental community that conducts biomedical research and development, medical materiel management, global medical communications and the study of foreign plant pathogens. The lab is known to research pathogens such as Ebola and smallpox. It is home to the U.S. Army Medical Research and Development Command (USAMRDC), with its bio-defense agency, the U.S. Army Medical Research Institute of Infectious Diseases (USAMRIID). It also hosts the National Cancer Institute-Frederick (NCI-Frederick) and is home to the National Interagency Confederation for Biological Research (NICBR) and National Interagen ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
United States Army Biological Warfare Laboratories
The U.S. Army Biological Warfare Laboratories (USBWL) were a suite of research laboratories and pilot plant centers operating at Camp (later Fort) Detrick, Maryland, United States beginning in 1943 under the control of the U.S. Army Chemical Corps Research and Development Command. The USBWL undertook research and development into biocontainment, decontamination, gaseous sterilization, and agent production and purification for the U.S. offensive biological warfare program. The laboratories and their projects were discontinued in 1969. History Origins The USBWL were created after Secretary of War Henry L. Stimson requested the National Academy of Sciences (NAS) in 1941 to review the feasibility of biological warfare (BW). The following year, the NAS reported that BW might be feasible and recommended that steps be taken to reduce U.S. vulnerability to BW attack. Thereafter, the official policy of the United States was first to deter the use of BW against U.S. forces, and secondar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Botulinum Toxin
Botulinum toxin, or botulinum neurotoxin (BoNT), is a neurotoxic protein produced by the bacterium ''Clostridium botulinum'' and related species. It prevents the release of the neurotransmitter acetylcholine from axon endings at the neuromuscular junction, thus causing flaccid paralysis. The toxin causes the disease botulism. The toxin is also used commercially for medical and cosmetic purposes. The seven main types of botulinum toxin are named types A to G (A, B, C1, C2, D, E, F and G). New types are occasionally found. Types A and B are capable of causing disease in humans, and are also used commercially and medically. Types C–G are less common; types E and F can cause disease in humans, while the other types cause disease in other animals. Botulinum toxins are among the most potent toxins known. Intoxication can occur naturally as a result of either wound or intestinal infection or by ingesting formed toxin in food. The estimated human lethal dose of type A toxin is 1.3 ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Saxitoxin
Saxitoxin (STX) is a potent neurotoxin and the best-known paralytic shellfish toxin (PST). Ingestion of saxitoxin by humans, usually by consumption of shellfish contaminated by toxic algal blooms, is responsible for the illness known as paralytic shellfish poisoning (PSP). The term saxitoxin originates from the genus name of the butter clam (''Saxidomus'') from which it was first isolated. But the term saxitoxin can also refer to the entire suite of more than 50 structurally related neurotoxins (known collectively as "saxitoxins") produced by protists, algae and cyanobacteria which includes saxitoxin itself (STX), neosaxitoxin (NSTX), gonyautoxins (GTX) and decarbamoylsaxitoxin (dcSTX). Saxitoxin has a large environmental and economic impact, as its presence in bivalve shellfish such as mussels, clams, oysters and scallops frequently leads to bans on commercial and recreational shellfish harvesting in many temperate coastal waters around the world including the Northeastern and W ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anthrax
Anthrax is an infection caused by the bacterium ''Bacillus anthracis''. It can occur in four forms: skin, lungs, intestinal, and injection. Symptom onset occurs between one day and more than two months after the infection is contracted. The skin form presents with a small blister with surrounding swelling that often turns into a painless ulcer with a black center. The inhalation form presents with fever, chest pain and shortness of breath. The intestinal form presents with diarrhea (which may contain blood), abdominal pains, nausea and vomiting. The injection form presents with fever and an abscess at the site of drug injection. According to the USA's Centers for Disease Control and Prevention, the first clinical descriptions of cutaneous anthrax were given by Maret in 1752 and Fournier in 1769. Before that anthrax had been described only through historical accounts. The Prussian scientist Robert Koch (1843–1910) was the first to identify ''Bacillus anthracis'' as the bacteri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Tularemia
Tularemia, also known as rabbit fever, is an infectious disease caused by the bacterium ''Francisella tularensis''. Symptoms may include fever, skin ulcers, and enlarged lymph nodes. Occasionally, a form that results in pneumonia or a throat infection may occur. The bacterium is typically spread by ticks, deer flies, or contact with infected animals. It may also be spread by drinking contaminated water or breathing in contaminated dust. It does not spread directly between people. Diagnosis is by blood tests or cultures of the infected site. Prevention is by using insect repellent, wearing long pants, rapidly removing ticks, and not disturbing dead animals. Treatment is typically with the antibiotic streptomycin. Gentamicin, doxycycline, or ciprofloxacin may also be used. Between the 1970s and 2015, around 200 cases were reported in the United States a year. Males are affected more often than females. It occurs most frequently in the young and the middle aged. In the United St ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Anthrax
Anthrax is an infection caused by the bacterium ''Bacillus anthracis''. It can occur in four forms: skin, lungs, intestinal, and injection. Symptom onset occurs between one day and more than two months after the infection is contracted. The skin form presents with a small blister with surrounding swelling that often turns into a painless ulcer with a black center. The inhalation form presents with fever, chest pain and shortness of breath. The intestinal form presents with diarrhea (which may contain blood), abdominal pains, nausea and vomiting. The injection form presents with fever and an abscess at the site of drug injection. According to the USA's Centers for Disease Control and Prevention, the first clinical descriptions of cutaneous anthrax were given by Maret in 1752 and Fournier in 1769. Before that anthrax had been described only through historical accounts. The Prussian scientist Robert Koch (1843–1910) was the first to identify ''Bacillus anthracis'' as the bacteri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Biological Weapons
A biological agent (also called bio-agent, biological threat agent, biological warfare agent, biological weapon, or bioweapon) is a bacterium, virus, protozoan, parasite, fungus, or toxin that can be used purposefully as a weapon in bioterrorism or biological warfare (BW). In addition to these living or replicating pathogens, toxins and biotoxins are also included among the bio-agents. More than 1,200 different kinds of potentially weaponizable bio-agents have been described and studied to date. Biological agents have the ability to adversely affect human health in a variety of ways, ranging from relatively mild allergic reactions to serious medical conditions, including serious injury, as well as serious or permanent disability or even death. Many of these organisms are ubiquitous in the natural environment where they are found in water, soil, plants, or animals. Bio-agents may be amenable to "weaponization" to render them easier to deploy or disseminate. Genetic modification m ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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