Baylisascariasis
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Baylisascariasis
''Baylisascaris procyonis'', also known by the common name of raccoon roundworm, is a roundworm nematode, found ubiquitously in raccoons, the definitive hosts. It is named after H. A. Baylis, who studied them in the 1920s–30s, and Greek ''askaris'' (intestinal worm). ''Baylisascaris'' larvae in paratenic hosts can migrate, causing visceral larva migrans (VLM). Baylisascariasis as the zoonotic infection of humans is rare, though extremely dangerous due to the ability of the parasite's larvae to migrate into brain tissue and cause damage. Concern for human infection has been increasing over the years due to urbanization of rural areas resulting in the increase in proximity and potential human interaction with raccoons. Signs and symptoms The potential for human infection was noted in 1969 by Paul C. Beaver, who studied infected mice, and the first case was reported 15 years later. Human infection with ''B. procyonis'' has been relatively rare, with about 30 cases reported since 1 ...
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Zoonotic
A zoonosis (; plural zoonoses) or zoonotic disease is an infectious disease of humans caused by a pathogen (an infectious agent, such as a bacterium, virus, parasite or prion) that has jumped from a non-human (usually a vertebrate) to a human. Typically, the first infected human transmits the infectious agent to at least one other human, who, in turn, infects others. Major modern diseases such as Ebola virus disease and salmonellosis are zoonoses. HIV was a zoonotic disease transmitted to humans in the early part of the 20th century, though it has now evolved into a separate human-only disease. Most strains of influenza that infect humans are human diseases, although many strains of bird flu and swine flu are zoonoses; these viruses occasionally recombine with human strains of the flu and can cause pandemics such as the 1918 Spanish flu or the 2009 swine flu. ''Taenia solium'' infection is one of the neglected tropical diseases with public health and veterinary concern in ende ...
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Albendazole
Albendazole (also known as albendazolum) is a broad-spectrum anthelmintic and antiprotozoal agent of the benzimidazole type. It is used for the treatment of a variety of intestinal parasite infections, including ascariasis, pinworm infection, hookworm infection, trichuriasis, strongyloidiasis, taeniasis, clonorchiasis, opisthorchiasis, cutaneous larva migrans, giardiasis, and gnathostomiasis, among other diseases. Common side effects include nausea, abdominal pain, and headache. Rare but potentially serious side effects include bone marrow suppression which usually improves on discontinuing the medication. Liver inflammation has been reported and those with prior liver problems are at greater risk. It is pregnancy category C in the United States and category D in Australia, meaning it may cause harm if taken by pregnant women. Albendazole was developed in 1975. It is on the World Health Organization's List of Essential Medicines. Medical uses Albendazole is an effective tr ...
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Baylisascaris
''Baylisascaris'' is a genus of roundworms that infect more than fifty animal species. Life cycle ''Baylisascaris'' eggs are passed in feces and become active within a month. They can remain viable in the environment for years, withstanding heat and cold. Animals become infested either by swallowing the eggs or eating another animal infested with ''Baylisascaris.'' Disease progression After an animal swallows the eggs, the microscopic larvae hatch in the intestine and invade the intestinal wall. If they are in their definitive host they develop for several weeks, then enter the intestinal lumen, mature, mate, and produce eggs, which are carried out in the fecal stream. If the larvae are in a paratenic host, they break into the bloodstream and enter various organs, particularly the central nervous system. A great deal of damage occurs wherever the larva try to make a home. In response to the attack, the body attempts to destroy it by walling it off or killing it. The larva moves ...
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Visceral Larva Migrans
Visceral larva migrans (VLM) is a condition in humans caused by the migratory larvae of certain nematodes, humans being a dead-end host, and was first reported in 1952. Nematodes causing such zoonotic infections are ''Baylisascaris procyonis'', ''Toxocara canis'', ''Toxocara cati'', and ''Ascaris suum''. These nematodes can infect but not mature in humans and after migrating through the intestinal wall, travel with the blood stream to various organs where they cause inflammation and damage. Affected organs can include the liver, heart (causing myocarditis) and the CNS (causing dysfunction, seizures, and coma). A special variant is ocular larva migrans where usually ''T. canis'' larvae travel to the eye. Only a few roundworm eggs are necessary to cause larva migrans in the human child or adult. However, visceral larva migrans seems to affect children aged 1–4 more often while ocular larva migrans more frequently affects children aged 7–8. Between 4.6% and 23% of U.S. childr ...
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Gnathostoma
''Gnathostoma'' is a genus of parasitic nematodes. The species ''Gnathostoma spinigerum'' and ''Gnathostoma hispidum'' can cause gnathostomiasis. Neurognathostomiasis occurs in the USA. ''Gnathostoma binucleatum'' (which is native to the Americas) has not been previously reported to cause neurognathostomiasis, suggesting that ''G. spinigerum'' has been introduced to the Americas, but a survey of isolates has not confirmed this. Species * ''Gnathostoma binucleatum'' (Almeyda-. Artigas, 1991) * ''Gnathostoma doloresi'' * ''Gnathostoma hispidum'' (Fedtschenko, 1872) * ''Gnathostoma lamothei'' * ''Gnathostoma malaysiae'' (Miyazaki & Dunn, 1965) * ''Gnathostoma nipponicum'' * ''Gnathostoma spinigerum'' Levinsen, 1889 * ''Gnathostoma turgidum ''Gnathostoma'' is a genus of parasitic nematodes. The species ''Gnathostoma spinigerum'' and ''Gnathostoma hispidum'' can cause gnathostomiasis. Neurognathostomiasis occurs in the USA. ''Gnathostoma binucleatum'' (which is native to th ...
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Angiostrongylus
''Angiostrongylus'' is a genus of parasitic nematodes in the family Metastrongylidae. Species Species in the genus * ''Angiostrongylus cantonensis ''Angiostrongylus cantonensis'' is a parasitic nematode (roundworm) that causes angiostrongyliasis, the most common cause of eosinophilic meningitis in Southeast Asia and the Pacific Basin. The nematode commonly resides in the pulmonary arteries ...'' (Chen, 1935) * '' Angiostrongylus costaricensis'' Morera & Cespedes, 1971 * '' Angiostrongylus vasorum'' Baillet, 1866 References Strongylida Secernentea genera {{Secernentea-stub ...
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Ancylostoma
''Ancylostoma'' is a genus of nematodes that includes some species of hookworms. Species include: : '' Ancylostoma braziliense'', commonly infects cats, popularly known in Brazil as ''bicho-geográfico'' : '' Ancylostoma caninum'', commonly infects dogs : '' Ancylostoma ceylanicum'' : ''Ancylostoma duodenale ''Ancylostoma'' is a genus of nematodes that includes some species of hookworms. Species include: : '' Ancylostoma braziliense'', commonly infects cats, popularly known in Brazil as ''bicho-geográfico'' : '' Ancylostoma caninum'', commonly infe ...'' : '' Ancylostoma pluridentatum'', commonly infects sylvatic cats : '' Ancylostoma tubaeforme'', infects cats along with other hosts See also * Ancylostomiasis * List of parasites (human) External links * Ancylostomatidae Rhabditida genera {{Rhabditida-stub ...
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Alae (anatomy)
The alae is a protruding ridge that forms longitudinally on many nematodes. In the ''Caenorhabditis elegans'' nematode they are present in the L1, dauer (an alternative long living larvae stage where the nematode is dormant) and adult stages. The alae are most pronounced during the dauer larval stage and not present in the L2, and L3 ''C. elegans'' stages. The term ‘alae’ is the plural of ala (wing), describing either one of the pair of ridges that forms on a nematode or an individual crease found on an individual ridge. The term ‘ala’ is rarely used in describing the alae and scientific journals use the term ‘alae’ both singularly and in the plural. Structure The alae is formed by the hypodermal seam cells where a fibrous ribbon of a zona pellucida (ZP) domain protein is produced. In ''C. elegans'' many of these proteins are termed CUT-1. The CUT refers to cuticulins which are the various proteins that are not solubilised by both reducing agents and detergents ...
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Infectious Disease (medical Speciality)
Infectious diseases or ID, also known as infectiology, is a medical specialty dealing with the diagnosis and treatment of infections. An infectious diseases specialist's practice consists of managing nosocomial ( healthcare-acquired) infections or community-acquired infections and is historically associated with hygiene, epidemiology, clinical microbiology, travel medicine and tropical medicine. Scope Infectious diseases specialists typically serve as consultants to other physicians in cases of complex infections, and often manage patients with HIV/AIDS and other forms of immunodeficiency. Although many common infections are treated by physicians without formal expertise in infectious diseases, specialists may be consulted for cases where an infection is difficult to diagnose or manage. They may also be asked to help determine the cause of a fever of unknown origin. Specialists in infectious diseases can practice both in hospitals (inpatient) and clinics (outpatient). In hospitals ...
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Serologic
Serology is the scientific study of serum and other body fluids. In practice, the term usually refers to the diagnostic identification of antibodies in the serum. Such antibodies are typically formed in response to an infection (against a given microorganism), against other foreign proteins (in response, for example, to a mismatched blood transfusion), or to one's own proteins (in instances of autoimmune disease). In either case, the procedure is simple. Serological tests Serological tests are diagnostic methods that are used to identify antibodies and antigens in a patient's sample. Serological tests may be performed to diagnose infections and autoimmune illnesses, to check if a person has immunity to certain diseases, and in many other situations, such as determining an individual's blood type. Serological tests may also be used in forensic serology to investigate crime scene evidence. Several methods can be used to detect antibodies and antigens, including ELISA, agglutination, ...
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Toxocara Cati
''Toxocara cati'', also known as the feline roundworm, is a parasite of cats and other felids. It is one of the most common nematodes of cats, infecting both wild and domestic felids worldwide. Adult worms are localised in the gut of the host. In adult cats, the infection – which is called toxocariasis – is usually asymptomatic. However, massive infection in juvenile cats can be fatal. Feline roundworms are brownish-yellow to cream-colored to pink and may be up to 10 cm in length. Adults have short, wide cervical alae giving their anterior ends the distinct appearance of an arrow (hence their name, ''toxo'', meaning arrow, and ''cara,'' meaning head). Eggs are pitted ovals with a width of 65  μm and a length of about 75 μm making them invisible to the human eye. The larvae are so small that they are easily transmitted from an adult female to her nursing kittens through her milk. Transmission Wild felids can become infected from a variety of sources; the pri ...
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Brain Biopsy
Brain biopsy is the removal of a small piece of brain tissue for the diagnosis of abnormalities of the brain. It is used to diagnose tumors, infection, inflammation, and other brain disorders. By examining the tissue sample under a microscope, the biopsy sample provides information about the appropriate diagnosis and treatment. Indications Given the potential risks surrounding the procedure, cerebral biopsy is indicated only if other diagnostic approaches (e.g. magnetic resonance imaging) have been insufficient in showing the cause of symptoms, and if it is felt that the benefits of histological diagnosis will influence the treatment plan. If the person has a brain tumor, biopsy is 95% sensitive. The procedure can also be valuable in people who are immunocompromised and who have evidence of brain lesions that could be caused by opportunistic infection An opportunistic infection is an infection caused by pathogens (bacteria, fungi, parasites or viruses) that take advantage of an ...
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