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Basem Al-Shayeb
Basem Al-Shayeb is a researcher at the Innovative Genomics Institute. He led the discovery of the largest known bacteriophages, the smallest CRISPR gene editing systems, and Borgs in methane-oxidizing archaea. He was named Forbes 30 Under 30 ''Forbes'' 30 Under 30 is a set of lists of people under 30 years old issued annually by ''Forbes'' magazine and some of its regional editions. The American lists recognize 600 business and industry figures, with 30 selected in twenty industries ... and Arab America's 30 Under 30. References Year of birth missing (living people) Living people {{more cats, date=November 2022 ...
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Bacteriophage
A bacteriophage (), also known informally as a ''phage'' (), is a duplodnaviria virus that infects and replicates within bacteria and archaea. The term was derived from "bacteria" and the Greek φαγεῖν ('), meaning "to devour". Bacteriophages are composed of proteins that encapsulate a DNA or RNA genome, and may have structures that are either simple or elaborate. Their genomes may encode as few as four genes (e.g. MS2) and as many as hundreds of genes. Phages replicate within the bacterium following the injection of their genome into its cytoplasm. Bacteriophages are among the most common and diverse entities in the biosphere. Bacteriophages are ubiquitous viruses, found wherever bacteria exist. It is estimated there are more than 1031 bacteriophages on the planet, more than every other organism on Earth, including bacteria, combined. Viruses are the most abundant biological entity in the water column of the world's oceans, and the second largest component of biom ...
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CRISPR Gene Editing
CRISPR gene editing (pronounced "crisper") is a genetic engineering technique in molecular biology by which the genomes of living organisms may be modified. It is based on a simplified version of the bacterial CRISPR-Cas9 antiviral defense system. By delivering the Cas9 nuclease complexed with a synthetic guide RNA (gRNA) into a cell, the cell's genome can be cut at a desired location, allowing existing genes to be removed and/or new ones added ''in vivo''. The technique is considered highly significant in biotechnology and medicine as it enables editing genomes ''in vivo'' very precisely, cheaply, and easily. It can be used in the creation of new medicines, agricultural products, and genetically modified organisms, or as a means of controlling pathogens and pests. It also has possibilities in the treatment of inherited genetic diseases as well as diseases arising from somatic mutations such as cancer. However, its use in human germline genetic modification is highly controve ...
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Borg (microbiology)
A borg is a "giant extrachromosomal element with the potential to augment methane oxidation", described by Basem Al-Shayeb and Jill Banfield. Borgs are long DNA sequences existing alongside the main chromosome in the archaea '' Methanoperedens'', in oxygen-starved environments such as deep mud. Borgs are considered to be a new form of "giant linear plasmids" or giant viruses rather than unknown DNA elements. They co-occur within a species of archaea which likely hosts them and shares many of their genes. The archaeon's main chromosome is only three times larger, and their capacity for anaerobic oxidation of methane Anaerobic means "living, active, occurring, or existing in the absence of free oxygen", as opposed to aerobic which means "living, active, or occurring only in the presence of oxygen." Anaerobic may also refer to: * Anaerobic adhesive, a bonding a ... as well as other biological functions – such as production of proteins – may be augmented by borgs. Reference ...
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Forbes 30 Under 30
''Forbes'' 30 Under 30 is a set of lists of people under 30 years old issued annually by ''Forbes'' magazine and some of its regional editions. The American lists recognize 600 business and industry figures, with 30 selected in twenty industries each. Asia and Europe also each have ten categories for a total of 300 each, while Africa has a single list of 30 people. ''Forbes'' hosts associated conferences and a section of its website called 30 Under 30. History ''Forbes'' launched its 30 Under 30 list in 2011 under the direction of Randall Lane. By 2016, the nominations for the list had reached more than 15,000, with ''Forbes'' editors selecting 30 winners for each of 20 categories. Over time, ''Forbes'' has expanded the feature to establish continental lists for Asia, Europe (launched in 2016), and Africa. ''Forbes'' also uses the Under 30 name for a dedicated channel on its website, associated with a 30 Under 30 social media app. ''The Washington Post'' reports the channel aim ...
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Year Of Birth Missing (living People)
A year or annus is the orbital period of a planetary body, for example, the Earth, moving in its orbit around the Sun. Due to the Earth's axial tilt, the course of a year sees the passing of the seasons, marked by change in weather, the hours of daylight, and, consequently, vegetation and soil fertility. In temperate and subpolar regions around the planet, four seasons are generally recognized: spring, summer, autumn and winter. In tropical and subtropical regions, several geographical sectors do not present defined seasons; but in the seasonal tropics, the annual wet and dry seasons are recognized and tracked. A calendar year is an approximation of the number of days of the Earth's orbital period, as counted in a given calendar. The Gregorian calendar, or modern calendar, presents its calendar year to be either a common year of 365 days or a leap year of 366 days, as do the Julian calendars. For the Gregorian calendar, the average length of the calendar year (the ...
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