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Baker IDI Heart And Diabetes Institute
The Baker Heart and Diabetes Institute, commonly known as the Baker Institute, is an Australian independent medical research research institute, institute headquartered in Melbourne, Victoria (Australia), Victoria. Established in 1926, the institute is one of Australia's oldest medical research organisations with a historical focus on cardiovascular disease. In 2008, it became the country's first medical research institute to target diabetes, heart disease, obesity and their complications at the basic, clinical and population health levels. The institute is located adjacent to The Alfred Hospital within the Alfred Research Alliance Precinct. The institute also has a national Indigenous health in Australia, Aboriginal Health program, with a research facility in Alice Springs in the Northern Territory. Research The Baker Institute's work ranges from cellular and molecular biology research in the laboratory to clinical-based research through to lifestyle and behavioural research th ...
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Medical Research
Medical research (or biomedical research), also known as experimental medicine, encompasses a wide array of research, extending from "basic research" (also called ''bench science'' or ''bench research''), – involving fundamental scientific principles that may apply to a ''preclinical'' understanding – to clinical research, which involves studies of people who may be subjects in clinical trials. Within this spectrum is applied research, or translational research, conducted to expand knowledge in the field of medicine. Both clinical and preclinical research phases exist in the pharmaceutical industry's drug development pipelines, where the clinical phase is denoted by the term ''clinical trial''. However, only part of the clinical or preclinical research is oriented towards a specific pharmaceutical purpose. The need for fundamental and mechanism-based understanding, diagnostics, medical devices, and non-pharmaceutical therapies means that pharmaceutical research i ...
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Mitral Valve
The mitral valve (), also known as the bicuspid valve or left atrioventricular valve, is one of the four heart valves. It has two cusps or flaps and lies between the left atrium and the left ventricle of the heart. The heart valves are all one-way valves allowing blood flow in just one direction. The mitral valve and the tricuspid valve are known as the atrioventricular valves because they lie between the atria and the ventricles. In normal conditions, blood flows through an open mitral valve during diastole with contraction of the left atrium, and the mitral valve closes during systole with contraction of the left ventricle. The valve opens and closes because of pressure differences, opening when there is greater pressure in the left atrium than ventricle and closing when there is greater pressure in the left ventricle than atrium. In abnormal conditions, blood may flow backward through the valve ( mitral regurgitation) or the mitral valve may be narrowed (mitral stenosis). Rh ...
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Epigenetics
In biology, epigenetics is the study of stable phenotypic changes (known as ''marks'') that do not involve alterations in the DNA sequence. The Greek prefix '' epi-'' ( "over, outside of, around") in ''epigenetics'' implies features that are "on top of" or "in addition to" the traditional genetic basis for inheritance. Epigenetics most often involves changes that affect the regulation of gene expression, but the term can also be used to describe any heritable phenotypic change. Such effects on cellular and physiological phenotypic traits may result from external or environmental factors, or be part of normal development. The term also refers to the mechanism of changes: functionally relevant alterations to the genome that do not involve mutation of the nucleotide sequence. Examples of mechanisms that produce such changes are DNA methylation and histone modification, each of which alters how genes are expressed without altering the underlying DNA sequence. Gene expression c ...
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University Of Queensland
, mottoeng = By means of knowledge and hard work , established = , endowment = A$224.3 million , budget = A$2.1 billion , type = Public research university , chancellor = Peter Varghese , vice_chancellor = Deborah Terry , city = Brisbane, Queensland, Australia , students = 55,305 (2019) , undergrad = 35,051 (2019) , postgrad = 19,939 (2019) , faculty = 2,854 , campus = Multiple sites , colours = Purple , affiliations = Group of EightUniversitas 21 ASAIHL EdX , website = , logo = Logo of the University of Queensland.svg , coor = The University of Queensland (UQ, or Queensland University) is a public research university located primarily in Brisbane, the capital city of the Australian state of Queensland. Founded in 1909 by the Queensland parliament, UQ is one of the six sandstone universities, an informal designation of the oldest university in each state. As per 2023, The University of Queensland is ranked as 2nd in Australia and 42nd in the world. Al ...
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University Of Melbourne
The University of Melbourne is a public research university located in Melbourne, Australia. Founded in 1853, it is Australia's second oldest university and the oldest in Victoria. Its main campus is located in Parkville, an inner suburb north of Melbourne's central business district, with several other campuses located across Victoria. Incorporated in the 19th century by the colony of Victoria, the University of Melbourne is one of Australia's six sandstone universities and a member of the Group of Eight, Universitas 21, Washington University's McDonnell International Scholars Academy, and the Association of Pacific Rim Universities. Since 1872, many residential colleges have become affiliated with the university, providing accommodation for students and faculty, and academic, sporting and cultural programs. There are ten colleges located on the main campus and in nearby suburbs. The university comprises ten separate academic units and is associated with numerous institut ...
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ACE Inhibitors
Angiotensin-converting-enzyme inhibitors (ACE inhibitors) are a class of medication used primarily for the treatment of high blood pressure and heart failure. They work by causing relaxation of blood vessels as well as a decrease in blood volume, which leads to lower blood pressure and decreased oxygen demand from the heart. ACE inhibitors inhibit the activity of angiotensin-converting enzyme, an important component of the renin–angiotensin system which converts angiotensin I to angiotensin II, and hydrolyses bradykinin. Therefore, ACE inhibitors decrease the formation of angiotensin II, a vasoconstrictor, and increase the level of bradykinin, a peptide vasodilator. This combination is synergistic in lowering blood pressure. As a result of inhibiting the ACE enzyme in the bradykinin system, the ACE inhibitor drugs allow for increased levels of bradykinin which would normally be degraded. Bradykinin produces prostaglandin. This mechanism can explain the two most common side e ...
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J Clin Endocrinol Metab
''The Journal of Clinical Endocrinology and Metabolism'' is a peer-reviewed medical journal in the field of endocrinology and metabolism. The current editor-in-chief An editor-in-chief (EIC), also known as lead editor or chief editor, is a publication's editorial leader who has final responsibility for its operations and policies. The highest-ranking editor of a publication may also be titled editor, managing ... is Paul Stewart. References External links * Publications established in 1941 Endocrinology journals Monthly journals English-language journals {{med-journal-stub ...
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American Journal Of Clinical Nutrition
''The American Journal of Clinical Nutrition'' (''AJCN'') is a monthly peer-reviewed biomedical journal in the fields of dietetics and clinical nutrition. The journal was established in 1952 as the ''Journal of Clinical Nutrition'', edited by S.O. Waife and published by the Nutrition Press. It was continued in series under the present title from 1954 and was published by the American Society for Clinical Nutrition (ASCN).Catalog entry
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It is now published by the .< ...
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British Journal Of Nutrition
The ''British Journal of Nutrition'' is a peer-reviewed scientific journal covering research on animal and human nutrition. It was established in 1947 and is published by Cambridge University Press on behalf of The Nutrition Society. The editor-in-chief is Professor John Mathers of Newcastle University. According to the ''Journal Citation Reports'', the journal has a 2019 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 3.334. References External links * The Nutrition Society English-language journals Cambridge University Press academic journals Nutrition and dietetics journals Biweekly journals Publications established in 1947 Academic journals associated with learned and professional societies of the United Kingdom {{Science-journal-stub ...
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Eur J Clin Nutr
The ''European Journal of Clinical Nutrition'' is a monthly peer-reviewed medical journal covering nutrition science and published by the Springer Nature. It was established in 1947 by John Waterlow as ''Nutrition'' and renamed ''Journal of Human Nutrition'' in 1976. In 1982 its name was changed to ''Human Nutrition'' and the journal was split into two sections: ''Human Nutrition: Applied Nutrition'' and ''Human Nutrition: Clinical Nutrition''. These two sections were combined again in 1988 with the journal obtaining its current name. The editor-in-chief is Mario J. Soares (Curtin University). Abstracting and indexing The journal is abstracted and indexed in: According to the ''Journal Citation Reports'', '' European Journal of Clinical Nutrition'' has a 2020 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the l ...
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Diabetologia
''Diabetologia'' is a monthly peer-reviewed medical journal covering diabetology and is the official journal of the European Association for the Study of Diabetes. It is published by Springer Science+Business Media and the editor-in-chief is Hindrik Mulder (Lund University). According to the ''Journal Citation Reports'', the journal has a 2021 impact factor The impact factor (IF) or journal impact factor (JIF) of an academic journal is a scientometric index calculated by Clarivate that reflects the yearly mean number of citations of articles published in the last two years in a given journal, as i ... of 10.460, ranked 11/146 in Endocrinology and Metabolism. The 5-Year Impact Factor is 10.617. Previous editors The following persons have been editors-in-chief of the journal: References External links * {{Official website, http://www.diabetologia-journal.org Springer Science+Business Media academic journals Monthly journals English-language journals Endocrinology ...
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Medical Journal Of Australia
The ''Medical Journal of Australia'' is a peer-reviewed medical journal published 22 times a year. It is the official journal of the Australian Medical Association, published by Wiley on behalf of the Australasian Medical Publishing Company. The journal publishes editorials, original research, guideline summaries, narrative reviews, perspectives, medical education, reflections, and letters. The full text of every issue since January 2002 is available online. History Early origins The journal was established in 1856, when communication between Australian states and other English-speaking nations entailed long delays. The journal was both a platform for Australian medical research, as well as educational reviews summarising research done overseas. It has since been renamed several times: *''Australian Medical Journal'' (1856–1895) *''Intercolonial Quarterly Journal of Medicine and Surgery'' (1895–1896) *''Intercolonial Medical Journal of Australasia'' (1896–1909) *''Australian ...
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