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BPK may refer to: * Brookmans Park railway station, Hertfordshire, National Rail station code * Bruton's tyrosine kinase * Audit Board of Indonesia The Audit Board of Indonesia (Indonesian: ''Badan Pemeriksa Keuangan Republik Indonesia'', literally ''Financial Audit Board of the Republic of Indonesia'') is a high state body in Indonesia which is responsible for evaluation of management and ac ...

Brookmans Park Railway Station
Brookmans Park railway station serves the village of Brookmans Park in Hertfordshire, England. The station is located north of London Kings Cross on the East Coast Main Line, on the stretch between and . History The station was opened by the London and North Eastern Railway (LNER) on 19 July 1926. During World War II, the station played a small part in the signing of the Anglo-Soviet Treaty. On 21 May 1942, LNER Class A4 locomotive number 4495 ''Golden Fleece'' brought Soviet foreign minister Vyacheslav Molotov to the station, where he was met by his British counterpart Anthony Eden. The pair and their staff were then driven to the Chequers estate, where the treaty was negotiated. Facilities The station is only staffed part-time, with the ticket office being open 06:5010:00, Monday to Friday. Customer help points are available for assistance out of hours. Other facilities include passenger information displays and waiting shelters. Oyster Cards are not valid at the stat ...
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Bruton's Tyrosine Kinase
Bruton's tyrosine kinase (abbreviated Btk or BTK), also known as tyrosine-protein kinase BTK, is a tyrosine kinase that is encoded by the ''BTK'' gene in humans. BTK plays a crucial role in B cell development. Structure BTK contains five different protein interaction domains. These domains include an amino terminal pleckstrin homology (PH) domain, a proline-rich TEC homology (TH) domain, SRC homology (SH) domains SH2 and SH3, as well as a kinase domain with enzymatic activity. Function BTK plays a crucial role in B cell development as it is required for transmitting signals from the pre-B cell receptor that forms after successful immunoglobulin heavy chain rearrangement. It also has a role in mast cell activation through the high-affinity IgE receptor. Btk contains a PH domain that binds phosphatidylinositol (3,4,5)-trisphosphate (PIP3). PIP3 binding induces Btk to phosphorylate phospholipase C, which in turn hydrolyzes PIP2, a phosphatidylinositol, into two second mess ...
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