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BANP
Protein BANP is a protein that can be found in humans, it is encoded by the ''BANP'' gene. It is a member of the human gene family, " BEN-domain containing", which includes eight other genes: BEND2, BEND3, BEND4, BEND5, BEND6, BEND7, NACC1 (BEND8), and NACC2 (BEND9). BANP is a protein coding gene that is located in the Nucleoplasm. Its official name is BTG3 associated with nuclear protein. It plays a role in DNA binding, chromatin regulation, repressor, transcription regulation and the cell cycle process. In recombination BANP protein represses T-cell receptors to control recombination during transcription. As a tumor suppressor BANP negatively regulates p53 transcription in recombination. It can be expressed in various tissues in the body including the testis, spleen, and the placenta. Function This gene encodes a protein that binds to matrix attachment regions. The protein functions as a tumor suppressor and cell cycle The cell cycle, or cell-division cycle, is the s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
BEN Domain
In molecular biology, the BEN domain is a protein domain which is found in diverse proteins including: * SMAR1 (Scaffold/Matrix attachment region-binding protein 1; also known as BANP), a tumour-suppressor MAR-binding protein that down-regulates Cyclin D1 expression by recruiting HDAC1-mSin3A co-repressor complex at Cyclin D1 promoter locus; SMAR1 is the target of prostaglandin A2 (PGA2) induced growth arrest. * NACC1, a novel member of the POZ/BTB (Pox virus and Zinc finger/Bric-a-bracTramtrack Broad complex), but which varies from other proteins of this class in that it lacks the characteristic DNA-binding motif. * Mod(mdg4) isoform C, the modifier of the mdg4 locus in ''Drosophila melanogaster'' (Fruit fly), where mdg4 encodes chromatin proteins which are involved in position effect variegation, establishment of chromatin boundaries, nerve path finding, meiotic chromosome pairing and apoptosis. Trans-splicing of Mod(mdg4) produces at least 26 transcripts. * BEND2, a protein o ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
BEND2 (protein)
BEND2 is a protein that in humans is encoded by the ''BEND2'' gene. It is also found in other vertebrates, including mammals, birds, and reptiles. The expression of BEND2 in ''Homo sapiens'' is regulated and occurs at high levels in the skeletal muscle tissue of the male Testicle, testis and in the bone marrow. The presence of the BEN domains in the BEND2 protein indicates that this protein may be involved in Chromatin remodeling, chromatin modification and regulation. Gene Common aliases BEND2 stands for BEN domain containing 2 and is also known as CXorf20 (HGNC ID28509. Locus and size The locus for BEND2 is on the minus strand of the X chromosome at Xp22.13. The gene is approximately 58 kilobases in length. mRNA Alternative splicing BEND2 contains 14 exons which undergo alternative splicing to create five transcript variants that vary from 4,720 Base pair, base pairs (bp) to 2,144 bp in the mature mRNA. The longest and most complete transcript of the gene, variant ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
