Asifa Akhtar
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Asifa Akhtar
Asifa Akhtar is a Pakistani biologist who has made significant contributions to the field of chromosome regulation. She is Senior Group Leader and Director of the Department of Chromatin Regulation at the Max Planck Institute of Immunobiology and Epigenetics. Akhtar was awarded EMBO membership in 2013. She became the first international and female Vice President of the Max Planck Society's Biology and Medicine Section in July 2020. Academic career Originally from Karachi, Pakistan, Asifa Akhtar studied for a BSc in biology at University College London, moving to the Imperial Cancer Research Fund (now part of the Francis Crick Institute) to gain a PhD for studying transcriptional regulation in the lab of Richard Treisman. Akhtar's postdoctoral studies in chromatin regulation were carried out in Peter Becker’s lab Germany, at European Molecular Biology Laboratory (EMBL), Heidelberg and the Adolf Butenandt Institute, Munich. Akhtar became a group leader at EMBL in 2001, moving ...
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Karachi
Karachi (; ur, ; ; ) is the most populous city in Pakistan and 12th most populous city in the world, with a population of over 20 million. It is situated at the southern tip of the country along the Arabian Sea coast. It is the former capital of Pakistan and capital of the province of Sindh. Ranked as a beta-global city, it is Pakistan's premier industrial and financial centre, with an estimated GDP of over $200 billion ( PPP) . Karachi paid $9billion (25% of whole country) as tax during fiscal year July 2021 to May 2022 according to FBR report. Karachi is Pakistan's most cosmopolitan city, linguistically, ethnically, and religiously diverse, as well as one of Pakistan's most secular and socially liberal cities. Karachi serves as a transport hub, and contains Pakistan’s two largest seaports, the Port of Karachi and Port Qasim, as well as Pakistan's busiest airport, Jinnah International Airport. Karachi is also a media center, home to news channels, film and fashi ...
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Drosophila Melanogaster
''Drosophila melanogaster'' is a species of fly (the taxonomic order Diptera) in the family Drosophilidae. The species is often referred to as the fruit fly or lesser fruit fly, or less commonly the "vinegar fly" or "pomace fly". Starting with Charles W. Woodworth's 1901 proposal of the use of this species as a model organism, ''D. melanogaster'' continues to be widely used for biological research in genetics, physiology, microbial pathogenesis, and life history evolution. As of 2017, five Nobel Prizes have been awarded to drosophilists for their work using the insect. ''D. melanogaster'' is typically used in research owing to its rapid life cycle, relatively simple genetics with only four pairs of chromosomes, and large number of offspring per generation. It was originally an African species, with all non-African lineages having a common origin. Its geographic range includes all continents, including islands. ''D. melanogaster'' is a common pest in homes, restaurants, and othe ...
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21st-century Pakistani Scientists
The 1st century was the century spanning AD 1 ( I) through AD 100 ( C) according to the Julian calendar. It is often written as the or to distinguish it from the 1st century BC (or BCE) which preceded it. The 1st century is considered part of the Classical era, epoch, or historical period. The 1st century also saw the appearance of Christianity. During this period, Europe, North Africa and the Near East fell under increasing domination by the Roman Empire, which continued expanding, most notably conquering Britain under the emperor Claudius (AD 43). The reforms introduced by Augustus during his long reign stabilized the empire after the turmoil of the previous century's civil wars. Later in the century the Julio-Claudian dynasty, which had been founded by Augustus, came to an end with the suicide of Nero in AD 68. There followed the famous Year of Four Emperors, a brief period of civil war and instability, which was finally brought to an end by Vespasian, ninth Roman emperor ...
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Max Planck Institute Directors
Max or MAX may refer to: Animals * Max (dog) (1983–2013), at one time purported to be the world's oldest living dog * Max (English Springer Spaniel), the first pet dog to win the PDSA Order of Merit (animal equivalent of OBE) * Max (gorilla) (1971–2004), a western lowland gorilla at the Johannesburg Zoo who was shot by a criminal in 1997 Brands and enterprises * Australian Max Beer * Max Hamburgers, a fast-food corporation * MAX Index, a Hungarian domestic government bond index * Max Fashion, an Indian clothing brand Computing * MAX (operating system), a Spanish-language Linux version * Max (software), a music programming language * Commodore MAX Machine * Multimedia Acceleration eXtensions, extensions for HP PA-RISC Films * ''Max'' (1994 film), a Canadian film by Charles Wilkinson * ''Max'' (2002 film), a film about Adolf Hitler * ''Max'' (2015 film), an American war drama film Games * '' Dancing Stage Max'', a 2005 game in the ''Dance Dance Revolution'' series * ''DDRM ...
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Alumni Of University College London
Alumni (singular: alumnus (masculine) or alumna (feminine)) are former students of a school, college, or university who have either attended or graduated in some fashion from the institution. The feminine plural alumnae is sometimes used for groups of women. The word is Latin and means "one who is being (or has been) nourished". The term is not synonymous with "graduate"; one can be an alumnus without graduating ( Burt Reynolds, alumnus but not graduate of Florida State, is an example). The term is sometimes used to refer to a former employee or member of an organization, contributor, or inmate. Etymology The Latin noun ''alumnus'' means "foster son" or "pupil". It is derived from PIE ''*h₂el-'' (grow, nourish), and it is a variant of the Latin verb ''alere'' "to nourish".Merriam-Webster: alumnus
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Separate, but from the ...
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German Academy Of Sciences Leopoldina
The German National Academy of Sciences Leopoldina (german: Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften), short Leopoldina, is the national academy of Germany, and is located in Halle (Saale). Founded on January 1, 1652, based on academic models in Italy, it was originally named the ''Academia Naturae Curiosorum'' until 1687 when Emperor Leopold I raised it to an academy and named it after himself. It was since known under the German name ''Deutsche Akademie der Naturforscher Leopoldina'' until 2007, when it was declared to be Germany's National Academy of Sciences. History ' The Leopoldina was founded in the imperial city of Schweinfurt on 1 January 1652 under the Latin name sometimes translated into English as "Academy of the Curious as to Nature." It was founded by four local physicians- Johann Laurentius Bausch, the first president of the society, Johann Michael Fehr, Georg Balthasar Metzger, and Georg Balthasar Wohlfarth; and ...
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Leibniz Prize
The Gottfried Wilhelm Leibniz Prize (german: link=no, Förderpreis für deutsche Wissenschaftler im Gottfried Wilhelm Leibniz-Programm der Deutschen Forschungsgemeinschaft), in short Leibniz Prize, is awarded by the German Research Foundation to "exceptional scientists and academics for their outstanding achievements in the field of research". Since 1986, up to ten prizes are awarded annually to individuals or research groups working at a research institution in Germany or at a German research institution abroad. It is considered the most important research award in Germany. The prize is named after the German polymath and philosopher Gottfried Wilhelm Leibniz (1646–1716). It is one of the highest endowed research prizes in Germany with a maximum of €2.5 million per award. Past prize winners include Stefan Hell (2008), Gerd Faltings (1996), Peter Gruss (1994), Svante Pääbo (1992), Theodor W. Hänsch (1989), Erwin Neher (1987), Bert Sakmann (1987), Jürgen Habermas (1986), ...
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Feldberg Foundation
The Feldberg Foundation promotes scientific exchange between German and British scientists in the field of experimental medical research. The foundation is registered in Hamburg, Germany with the secretariat based in the UK. The pharmacologist Wilhelm Feldberg, who as a Jew had been forced to emigrate from Germany in 1933, used the pension he was given as Emeritus Professor in Germany and the restitution money that he received from the German Government to establish the Feldberg Foundation in 1961. Each year a German and a British scientist are chosen, and each recipient gives a prize lecture in the other one's country. Recipients 2011– 2001–2010 1991–2000 1981–1990 1971–1980 1961–1970 {, class="wikitable" , - ! Year !! British !! German , - , 1970 , , Thaddeus Mann, University of Cambridge , , , Technical University of Berlin , - , 1969 , , Marthe Louise Vogt, Babraham Institute , , , Ludwig Maximilian University of Munich , - , ...
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European Life Science Organisation
The European Molecular Biology Organization (EMBO) is a professional, non-profit organization of more than 1,800 life scientists. Its goal is to promote research in life science and enable international exchange between scientists. It co-funds courses, workshops and conferences, publishes five scientific journals and supports individual scientists. The organization was founded in 1964 and is a founding member of the Initiative for Science in Europe. the Director of EMBO is Fiona Watt, a stem cell researcher, professor at King's College London and a group leader at the European Molecular Biology Laboratory. Conferences and journals EMBO funds or co-funds over 90 meetings involving more than 11,000 participants every year. EMBO publishes five peer-reviewed scientific journals: '' The EMBO Journal'', ''EMBO Reports'', ''Molecular Systems Biology'', '' EMBO Molecular Medicine'', and ''Life Science Alliance'', History The European Molecular Biology Organization (EMBO) was launche ...
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Nucleosome
A nucleosome is the basic structural unit of DNA packaging in eukaryotes. The structure of a nucleosome consists of a segment of DNA wound around eight histone proteins and resembles thread wrapped around a spool. The nucleosome is the fundamental subunit of chromatin. Each nucleosome is composed of a little less than two turns of DNA wrapped around a set of eight proteins called histones, which are known as a histone octamer. Each histone octamer is composed of two copies each of the histone proteins H2A, H2B, H3, and H4. DNA must be compacted into nucleosomes to fit within the cell nucleus. In addition to nucleosome wrapping, eukaryotic chromatin is further compacted by being folded into a series of more complex structures, eventually forming a chromosome. Each human cell contains about 30 million nucleosomes. Nucleosomes are thought to carry epigenetically inherited information in the form of covalent modifications of their core histones. Nucleosome positions in the gen ...
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Transcription (biology)
Transcription is the process of copying a segment of DNA into RNA. The segments of DNA transcribed into RNA molecules that can encode proteins are said to produce messenger RNA (mRNA). Other segments of DNA are copied into RNA molecules called non-coding RNAs (ncRNAs). mRNA comprises only 1–3% of total RNA samples. Less than 2% of the human genome can be transcribed into mRNA ( Human genome#Coding vs. noncoding DNA), while at least 80% of mammalian genomic DNA can be actively transcribed (in one or more types of cells), with the majority of this 80% considered to be ncRNA. Both DNA and RNA are nucleic acids, which use base pairs of nucleotides as a complementary language. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, antiparallel RNA strand called a primary transcript. Transcription proceeds in the following general steps: # RNA polymerase, together with one or more general transcription factors, binds to promoter ...
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Transposon
A transposable element (TE, transposon, or jumping gene) is a nucleic acid sequence in DNA that can change its position within a genome, sometimes creating or reversing mutations and altering the cell's genetic identity and genome size. Transposition often results in duplication of the same genetic material. Barbara McClintock's discovery of them earned her a Nobel Prize in 1983. Its importance in personalized medicine is becoming increasingly relevant, as well as gaining more attention in data analytics given the difficulty of analysis in very high dimensional spaces. Transposable elements make up a large fraction of the genome and are responsible for much of the C-value, mass of DNA in a eukaryotic cell. Although TEs are selfish genetic elements, many are important in genome function and evolution. Transposons are also very useful to researchers as a means to alter DNA inside a living organism. There are at least two classes of TEs: Class I TEs or retrotransposons generally ...
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