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Asa Church
ASA as an abbreviation or initialism may refer to: Biology and medicine * Accessible surface area of a biomolecule, accessible to a solvent * Acetylsalicylic acid, aspirin * Advanced surface ablation, refractive eye surgery * Anterior spinal artery, the blood vessel which supplies the anterior portion of the spinal cord * Antisperm antibodies, antibodies against sperm antigens * Argininosuccinic aciduria, a disorder of the urea cycle * ASA physical status classification system, rating of patients undergoing anesthesia Education and research * African Studies Association of the United Kingdom * African Studies Association *Alandica Shipping Academy, Åland Islands, Finland * Albany Students' Association, at Massey University, Auckland, New Zealand * Alexander-Smith Academy, in Houston, Texas * Alpha Sigma Alpha, U.S. national sorority * American Society for Aesthetics, philosophical organization * American Student Assistance, national non-profit organization * American Studies A ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Accessible Surface Area
The accessible surface area (ASA) or solvent-accessible surface area (SASA) is the surface area of a biomolecule that is accessible to a solvent. Measurement of ASA is usually described in units of square angstroms (a standard unit of measurement in molecular biology). ASA was first described by Lee & Richards in 1971 and is sometimes called the Lee-Richards molecular surface. ASA is typically calculated using the 'rolling ball' algorithm developed by Shrake & Rupley in 1973. This algorithm uses a sphere (of solvent) of a particular radius to 'probe' the surface of the molecule. Methods of calculating ASA Shrake–Rupley algorithm The Shrake–Rupley algorithm is a numerical method that draws a mesh of points equidistant from each atom of the molecule and uses the number of these points that are solvent accessible to determine the surface area. The points are drawn at a water molecule's estimated radius beyond the van der Waals radius, which is effectively similar to ‘rollin ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |