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Animal Study Registry
Animal Study Registry is an online registry for the preregistration of research studies involving animals. Animal Study Registry was launched in January 2019 and can be used by scientists worldwide. History The reproducibility of animal test results in biomedical research has been questioned repeatedly in the past. Discussions about this replication crisis have already reached the public. In clinical research, the call for transparency led to the introduction of clinical trial registries that disclose the experimental design of clinical trials before the study is conducted. In order to increase the transparency and the quality in the field of preclinical and basic research, the establishment of so-called centralized animal study registries was suggested. The German Federal Institute for Risk Assessment (BfR), as a scientifically independent research institution, has decided to provide an international freely accessible platform for the pre-registration of studies involving anima ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Preregistration (science)
Preregistration is the practice of registering the hypotheses, methods, and/or analyses of a scientific study before it is conducted. This can include analyzing primary data or secondary data. Clinical trial registration is similar, although it may not require the registration of a study's analysis protocol. Finally, registered reports include the peer review and in principle acceptance of a study protocol prior to data collection. Preregistration assists in the identification and/or reduction of a variety of potentially problematic research practices, including p-hacking, publication bias, data dredging, inappropriate forms of post hoc analysis, and (relatedly) HARKing. It has recently gained prominence in the open science community as a potential solution to some of the issues that are thought to underlie the replication crisis. However, critics have argued that it may not be necessary when other open science practices are implemented such as Registered Reports. Types Standar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Replication Crisis
The replication crisis (also called the replicability crisis and the reproducibility crisis) is an ongoing methodological crisis in which the results of many scientific studies are difficult or impossible to reproduce. Because the reproducibility of empirical results is an essential part of the scientific method, such failures undermine the credibility of theories building on them and potentially call into question substantial parts of scientific knowledge. The replication crisis is frequently discussed in relation to psychology and medicine, where considerable efforts have been undertaken to reinvestigate classic results, to determine both their reliability and, if found unreliable, the reasons for the failure. Data strongly indicate that other natural, and social sciences are affected as well. The phrase ''replication crisis'' was coined in the early 2010s as part of a growing awareness of the problem. Considerations of causes and remedies have given rise to a new scientific ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Clinical Trial Registries
Preregistration is the practice of registering the hypotheses, methods, and/or analyses of a scientific study before it is conducted. This can include analyzing primary data or secondary data. Clinical trial registration is similar, although it may not require the registration of a study's analysis protocol. Finally, registered reports include the peer review and in principle acceptance of a study protocol prior to data collection. Preregistration assists in the identification and/or reduction of a variety of potentially problematic research practices, including p-hacking, publication bias, data dredging, inappropriate forms of post hoc analysis, and (relatedly) HARKing. It has recently gained prominence in the open science community as a potential solution to some of the issues that are thought to underlie the replication crisis. However, critics have argued that it may not be necessary when other open science practices are implemented such as Registered Reports. Types Standar ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
