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Animal Free Research UK
Animal Free Research UK (AFRUK), formerly the Dr Hadwen Trust, is a UK medical research charity that funds and promotes non-animal techniques to replace animal experiments.Pain Experts Say Greater Focus On High-Tech Non-Animal Research Could Help Thousands Of Patients 15 August 2008 Medical News Today Established in 1970, the work undertaken by Animal Free Research UK develops reliable science whilst avoiding animal testing. Originally registered with the Charity Commission as charity number 261096, as the Dr Hadwen Trust, the charity became incorporated as a charitable company (registered charity number 1146896) in 2013. In 2015, the Dr Hadwen Trust ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brain Tumour Research
Brain Tumour Research is a UK-based medical research charity dedicated to funding research, raising awareness of brain tumours. The charities vision is to find a cure for brain tumours of all kinds. The charity works with, and funds a network of experts in sustainable research at dedicated Centres of Excellence across the UK. The charity also focuses on influencing the Government and larger cancer charities to invest more nationally. History In 2004, an informal partnership of several regional UK charities working to raise funds for brain tumour research and support agreed to join forces under the banner of the United Brain Tumour Campaign, committing themselves to work together to increase awareness across the UK and achieve a common goal to raise funds specifically for research in the UK into the prevention and treatment of brain tumours. The Diana Ford Trust, a charity funding brain tumour research, re-registered as Brain Tumour Research in 2008, using their cash deposits to ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Dentistry
Dentistry, also known as dental medicine and oral medicine, is the branch of medicine focused on the teeth, gums, and mouth. It consists of the study, diagnosis, prevention, management, and treatment of diseases, disorders, and conditions of the mouth, most commonly focused on dentition (the development and arrangement of teeth) as well as the oral mucosa. Dentistry may also encompass other aspects of the craniofacial complex including the temporomandibular joint. The practitioner is called a dentist. The history of dentistry is almost as ancient as the history of humanity and civilization with the earliest evidence dating from 7000 BC to 5500 BC. Dentistry is thought to have been the first specialization in medicine which have gone on to develop its own accredited degree with its own specializations. Dentistry is often also understood to subsume the now largely defunct medical specialty of stomatology (the study of the mouth and its disorders and diseases) for which reas ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
In Silico
In biology and other experimental sciences, an ''in silico'' experiment is one performed on computer or via computer simulation. The phrase is pseudo-Latin for 'in silicon' (correct la, in silicio), referring to silicon in computer chips. It was coined in 1987 as an allusion to the Latin phrases , , and , which are commonly used in biology (especially systems biology). The latter phrases refer, respectively, to experiments done in living organisms, outside living organisms, and where they are found in nature. History The earliest known use of the phrase was by Christopher Langton to describe artificial life, in the announcement of a workshop on that subject at the Center for Nonlinear Studies at the Los Alamos National Laboratory in 1987. The expression ''in silico'' was first used to characterize biological experiments carried out entirely in a computer in 1989, in the workshop "Cellular Automata: Theory and Applications" in Los Alamos, New Mexico, by Pedro Miramontes, a ma ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Folding@home
Folding@home (FAH or F@h) is a volunteer computing project aimed to help scientists develop new therapeutics for a variety of diseases by the means of simulating protein dynamics. This includes the process of protein folding and the movements of proteins, and is reliant on simulations run on volunteers' personal computers. Folding@home is currently based at the University of Pennsylvania and led by Greg Bowman, a former student of Vijay Pande. The project utilizes graphics processing units (GPUs), central processing units (CPUs), and ARM processors like those on the Raspberry Pi for volunteer computing and scientific research. The project uses statistical simulation methodology that is a paradigm shift from traditional computing methods. As part of the client–server model network architecture, the volunteered machines each receive pieces of a simulation (work units), complete them, and return them to the project's database servers, where the units are compiled into an overa ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Computer Experiment
A computer experiment or simulation experiment is an experiment used to study a computer simulation, also referred to as an in silico system. This area includes computational physics, computational chemistry, computational biology and other similar disciplines. Background Computer simulations are constructed to emulate a physical system. Because these are meant to replicate some aspect of a system in detail, they often do not yield an analytic solution. Therefore, methods such as discrete event simulation or finite element solvers are used. A computer model is used to make inferences about the system it replicates. For example, climate models are often used because experimentation on an earth sized object is impossible. Objectives Computer experiments have been employed with many purposes in mind. Some of those include: * Uncertainty quantification: Characterize the uncertainty present in a computer simulation arising from unknowns during the computer simulation's construc ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Computational Biomodeling
Modelling biological systems is a significant task of systems biology and mathematical biology. Computational systems biology aims to develop and use efficient algorithms, data structures, visualization and communication tools with the goal of computer modelling of biological systems. It involves the use of computer simulations of biological systems, including cellular subsystems (such as the networks of metabolites and enzymes which comprise metabolism, signal transduction pathways and gene regulatory networks), to both analyze and visualize the complex connections of these cellular processes. An unexpected emergent property of a complex system may be a result of the interplay of the cause-and-effect among simpler, integrated parts (see biological organisation). Biological systems manifest many important examples of emergent properties in the complex interplay of components. Traditional study of biological systems requires reductive methods in which quantities of data are gathered ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Computational Biology
Computational biology refers to the use of data analysis, mathematical modeling and computational simulations to understand biological systems and relationships. An intersection of computer science, biology, and big data, the field also has foundations in applied mathematics, chemistry, and genetics. It differs from biological computing, a subfield of computer engineering which uses bioengineering to build computers. History Bioinformatics, the analysis of informatics processes in biological systems, began in the early 1970s. At this time, research in artificial intelligence was using network models of the human brain in order to generate new algorithms. This use of biological data pushed biological researchers to use computers to evaluate and compare large data sets in their own field. By 1982, researchers shared information via punch cards. The amount of data grew exponentially by the end of the 1980s, requiring new computational methods for quickly interpreting ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cellular Model
A cellular model is a mathematical model of aspects of a biological cell, for the purposes of in silico research. Developing such models has been a task of systems biology and mathematical biology. It involves developing efficient algorithms, data structures, visualization and communication tools to orchestrate the integration of large quantities of biological data with the goal of computer modeling. It involves the use of computer simulations of cellular subsystems, such as the networks of metabolites and enzymes which comprise metabolism, signal transduction pathways and gene regulatory networks.It is the preminary research of biology cells Overview The eukaryotic cell cycle is very complex and is one of the most studied topics, since its misregulation leads to cancers. It is possibly a good example of a mathematical model as it deals with simple calculus but gives valid results. Two research groups have produced several models of the cell cycle simulating several organisms. Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Three Rs (animal Research)
The Three Rs (3Rs) are guiding principles for more ethical use of animals in product testing and scientific research. They were first described by W. M. S. Russell and R. L. Burch in 1959.Russell, W.M.S. and Burch, R.L., (1959). ''The Principles of Humane Experimental Technique'', Methuen, London.A digital version of the Principles may be accessed for free on thwebsiteof Johns Hopkins University's Center for Alternatives to Animal Testing (CAAT). The 3Rs are: #Replacement: methods which avoid or replace the use of animals in research #Reduction: use of methods that enable researchers to obtain comparable levels of information from fewer animals, or to obtain more information from the same number of animals. #Refinement: use of methods that alleviate or minimize potential pain, suffering or distress, and enhance animal welfare for the animals used. The 3Rs have a broader scope than simply encouraging alternatives to animal testing, but aim to improve animal welfare and scientif ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
List Of Animal Rights Groups
This list of animal rights groups consists of groups in the animal rights movement. Such animal rights groups work towards their ideals, which include the viewpoint that animals should have equivalent rights to humans, such as not being "used" in research, food, clothing and entertainment industries, and seek to end the status of animals as property. (Cf. Animal welfare.) This list contains only groups, organizations and leaderless resistance networks that have articles within Wikipedia. Organizations General animal rights *American Society for the Prevention of Cruelty to Animals (ASPCA) *Animal Aid (UK) *Animal Defenders International *Animal Defense League *Animal Ethics *Animal Legal Defense Fund *Animal Liberation Leagues *Animal Liberation Press Office * Animal Outlook (formerly Compassion Over Killing) *Animal Protection and Rescue League *Animal Welfare Network Nepal * AnimaNaturalis (Spain and Latin America) *Animals Now *Anonymous for the Voiceless *Best Friends Anim ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
AIDS
Human immunodeficiency virus infection and acquired immunodeficiency syndrome (HIV/AIDS) is a spectrum of conditions caused by infection with the human immunodeficiency virus (HIV), a retrovirus. Following initial infection an individual may not notice any symptoms, or may experience a brief period of influenza-like illness. Typically, this is followed by a prolonged incubation period with no symptoms. If the infection progresses, it interferes more with the immune system, increasing the risk of developing common infections such as tuberculosis, as well as other opportunistic infections, and tumors which are rare in people who have normal immune function. These late symptoms of infection are referred to as acquired immunodeficiency syndrome (AIDS). This stage is often also associated with unintended weight loss. HIV is spread primarily by unprotected sex (including anal and vaginal sex), contaminated blood transfusions, hypodermic needles, and from mother to child duri ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Brain Tumor
A brain tumor occurs when abnormal cells form within the brain. There are two main types of tumors: malignant tumors and benign (non-cancerous) tumors. These can be further classified as primary tumors, which start within the brain, and secondary tumors, which most commonly have spread from tumors located outside the brain, known as brain metastasis tumors. All types of brain tumors may produce symptoms that vary depending on the size of the tumor and the part of the brain that is involved. Where symptoms exist, they may include headaches, seizures, problems with vision, vomiting and mental changes. Other symptoms may include difficulty walking, speaking, with sensations, or unconsciousness. The cause of most brain tumors is unknown. Uncommon risk factors include exposure to vinyl chloride, Epstein–Barr virus, ionizing radiation, and inherited syndromes such as neurofibromatosis, tuberous sclerosis, and von Hippel-Lindau Disease. Studies on mobile phone exposure hav ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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