Andrew Pecora
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Andrew Pecora
Andrew Louis Pecora (born 1957) is an American Hematology, hematologist and Oncology, oncologist involved in research on the use of stem cells and oncolytic viruses to treat diseases, including cancer. He is the CEO of Outcomes Matter Innovations. As of 2020, he is on the Board of Directors Celularity, Inc. (since 2017) and founder and Executive Chairman, COTA, Inc. (since 2012). Previously, he was Chief innovation officer, chief innovations officer, professor and vice president of cancer services at the John Theurer Cancer Center, part of the Hackensack University Medical Center. He is a professor of medicine and oncology at Georgetown University School of Medicine, Georgetown University. Early life and education Pecora was born in 1957 in Newark, New Jersey, Newark, New Jersey. He was raised in Nutley, New Jersey, Nutley and graduated Nutley High School. Pecora attended Seton Hall University, graduating in 1979 with Bachelor of Science in Biology. He then attended the Univers ...
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Chairman
The chairperson, also chairman, chairwoman or chair, is the presiding officer of an organized group such as a board, committee, or deliberative assembly. The person holding the office, who is typically elected or appointed by members of the group, presides over meetings of the group, and conducts the group's business in an orderly fashion. In some organizations, the chairperson is also known as ''president'' (or other title). In others, where a board appoints a president (or other title), the two terms are used for distinct positions. Also, the chairman term may be used in a neutral manner not directly implying the gender of the holder. Terminology Terms for the office and its holder include ''chair'', ''chairperson'', ''chairman'', ''chairwoman'', ''convenor'', ''facilitator'', '' moderator'', ''president'', and ''presiding officer''. The chairperson of a parliamentary chamber is often called the ''speaker''. ''Chair'' has been used to refer to a seat or office of authority ...
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Oncolytic Viruses
An oncolytic virus is a virus that preferentially infects and kills cancer cells. As the infected cancer cells are destroyed by oncolysis, they release new infectious virus particles or virions to help destroy the remaining tumour. Oncolytic viruses are thought not only to cause direct destruction of the tumour cells, but also to stimulate host anti-tumour immune system responses. Oncolytic viruses also have the ability to affect the tumor micro-environment in multiples ways. The potential of viruses as anti-cancer agents was first realised in the early twentieth century, although coordinated research efforts did not begin until the 1960s. A number of viruses including adenovirus, reovirus, measles, herpes simplex, Newcastle disease virus, and vaccinia have been clinically tested as oncolytic agents. Most current oncolytic viruses are engineered for tumour selectivity, although there are naturally occurring examples such as reovirus and the senecavirus, resulting in clinical tria ...
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Problem-based Learning
Problem-based learning (PBL) is a student-centered pedagogy in which students learn about a subject through the experience of solving an open-ended problem found in trigger material. The PBL process does not focus on problem solving with a defined solution, but it allows for the development of other desirable skills and attributes. This includes knowledge acquisition, enhanced group collaboration and communication. The PBL process was developed for medical education and has since been broadened in applications for other programs of learning. The process allows for learners to develop skills used for their future practice. It enhances critical appraisal, literature retrieval and encourages ongoing learning within a team environment. The PBL tutorial process often involves working in small groups of learners. Each student takes on a role within the group that may be formal or informal and the role often alternates. It is focused on the student's reflection and reasoning to construc ...
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Stem Cell
In multicellular organisms, stem cells are undifferentiated or partially differentiated cells that can differentiate into various types of cells and proliferate indefinitely to produce more of the same stem cell. They are the earliest type of cell in a cell lineage. They are found in both embryonic and adult organisms, but they have slightly different properties in each. They are usually distinguished from progenitor cells, which cannot divide indefinitely, and precursor or blast cells, which are usually committed to differentiating into one cell type. In mammals, roughly 50–150 cells make up the inner cell mass during the blastocyst stage of embryonic development, around days 5–14. These have stem-cell capability. ''In vivo'', they eventually differentiate into all of the body's cell types (making them pluripotent). This process starts with the differentiation into the three germ layers – the ectoderm, mesoderm and endoderm – at the gastrulation stage. However ...
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Hematopoietic Stem Cell Transplantation
Hematopoietic stem-cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood in order to replicate inside of a patient and to produce additional normal blood cells. It may be autologous (the patient's own stem cells are used), allogeneic (the stem cells come from a donor) or syngeneic (from an identical twin). It is most often performed for patients with certain cancers of the blood or bone marrow, such as multiple myeloma or leukemia. In these cases, the recipient's immune system is usually destroyed with radiation or chemotherapy before the transplantation. Infection and graft-versus-host disease are major complications of allogeneic HSCT. HSCT remains a dangerous procedure with many possible complications; it is reserved for patients with life-threatening diseases. As survival following the procedure has increased, its use has expanded beyond cancer to autoimmun ...
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Hematology
Hematology ( always spelled haematology in British English) is the branch of medicine concerned with the study of the cause, prognosis, treatment, and prevention of diseases related to blood. It involves treating diseases that affect the production of blood and its components, such as blood cells, hemoglobin, blood proteins, bone marrow, platelets, blood vessels, spleen, and the mechanism of coagulation. Such diseases might include hemophilia, blood clots (thrombus), other bleeding disorders, and blood cancers such as leukemia, multiple myeloma, and lymphoma. The laboratory analysis of blood is frequently performed by a medical technologist or medical laboratory scientist. Specialization Physicians specialized in hematology are known as hematologists or haematologists. Their routine work mainly includes the care and treatment of patients with hematological diseases, although some may also work at the hematology laboratory viewing blood films and bone marrow slides under the ...
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American Board Of Internal Medicine
The American Board of Internal Medicine (ABIM) is a 501(c)(3) nonprofit, self-appointed physician-evaluation organization that certifies physicians practicing internal medicine and its subspecialties. The American Board of Internal Medicine is not a membership society, educational institution, or licensing body. History The American Board of Internal Medicine was established on February 28th, 1936 by the American Medical Association and the American College of Physicians to issue certification to physicians. In 1989, ABIM began requiring maintenance of certification (MOC) examinations every 10 years for continued board certification. ABIM is the largest of 24 member certifying boards of the American Board of Medical Specialties. The American Board of Internal Medicine categorizes physicians into one or more of its 20 subspecialties based on training and the passing of a standardized exam, namely: * Adolescent Medicine * Adult Congenital Heart Disease * Advanced Heart Failure & T ...
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Bachelor Of Science
A Bachelor of Science (BS, BSc, SB, or ScB; from the Latin ') is a bachelor's degree awarded for programs that generally last three to five years. The first university to admit a student to the degree of Bachelor of Science was the University of London in 1860. In the United States, the Lawrence Scientific School first conferred the degree in 1851, followed by the University of Michigan in 1855. Nathaniel Southgate Shaler, who was Harvard's Dean of Sciences, wrote in a private letter that "the degree of Bachelor of Science came to be introduced into our system through the influence of Louis Agassiz, who had much to do in shaping the plans of this School." Whether Bachelor of Science or Bachelor of Arts degrees are awarded in particular subjects varies between universities. For example, an economics student may graduate as a Bachelor of Arts in one university but as a Bachelor of Science in another, and occasionally, both options are offered. Some universities follow the Oxford a ...
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Nutley High School
Nutley High School is a four-year comprehensive public high school in the Township of Nutley, in Essex County, New Jersey, United States, serving students in ninth through twelfth grades as the lone secondary school of the Nutley Public Schools. The school's colors are maroon and gray. The school has been accredited by the Middle States Association of Colleges and Schools Commission on Elementary and Secondary Schools since 1928.Nutley High School
Commission on Elementary and Secondary Schools. Accessed August 30, 2020.
Students pursue an appropr ...
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Nutley, New Jersey
Nutley is a township in Essex County, New Jersey, United States. As of the 2020 United States census, the township's population was 30,143. What is now Nutley was originally incorporated as Franklin Township by an act of the New Jersey Legislature on February 18, 1874, from portions of Belleville Township. Nutley was incorporated as a town on March 5, 1902, replacing Franklin Township.Snyder, John P''The Story of New Jersey's Civil Boundaries: 1606–1968'' Bureau of Geology and Topography; Trenton, New Jersey; 1969. p. 130 for Nutley, p. 128 for Franklin Township. Accessed June 1, 2012. In 1981, the town was one of seven Essex County municipalities to pass a referendum to become a township, joining four municipalities that had already made the change, of what would ultimately be more than a dozen Essex County municipalities to reclassify themselves as townships in order take advantage of federal revenue sharing policies that allocated townships a greater share of government ai ...
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New Jersey
New Jersey is a state in the Mid-Atlantic and Northeastern regions of the United States. It is bordered on the north and east by the state of New York; on the east, southeast, and south by the Atlantic Ocean; on the west by the Delaware River and Pennsylvania; and on the southwest by Delaware Bay and the state of Delaware. At , New Jersey is the fifth-smallest state in land area; but with close to 9.3 million residents, it ranks 11th in population and first in population density. The state capital is Trenton, and the most populous city is Newark. With the exception of Warren County, all of the state's 21 counties lie within the combined statistical areas of New York City or Philadelphia. New Jersey was first inhabited by Native Americans for at least 2,800 years, with the Lenape being the dominant group when Europeans arrived in the early 17th century. Dutch and Swedish colonists founded the first European settlements in the state. The British later seized control o ...
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Georgetown University School Of Medicine
Georgetown University School of Medicine, a medical school opened in 1851, is one of Georgetown University's five graduate schools. It is located on Reservoir Road in the Georgetown neighborhood of Washington, DC, adjacent to the University's main campus. The School of Medicine works in association with the 609-bed MedStar Georgetown University Hospital, MedStar Washington Hospital Center, and nine other affiliated federal and community hospitals in the Washington metropolitan area. Georgetown is the oldest Catholic medical school in the United States. The School is part of the Georgetown University Medical Center, which comprises roughly 80% of the research initiatives occurring at Georgetown University as a whole. It is the closest academic medical center in proximity to the National Institutes of Health. Georgetown and the NIH offer a combined GU-NIH PhD program in biomedical research to foster direct collaboration between the neighboring institutions. The School is ranked ...
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