Andre Franke
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Andre Franke
Andre Franke, born on 16 October 1978, is a geneticist, academic, and university professor. He is a Full W3 Professor of Molecular Medicine at the Christian-Albrechts-University of Kiel, and a managing director at the Institute of Clinical Molecular Biology. Franke is most known for his work on genetics, genome-wide association studies, microbiome, and internal medicine research. He integrates bioinformatics developments with novel technologies, chronic inflammatory diseases, and has studied the genetic architecture of different complex diseases and traits. Education Franke enrolled at the Christian-Albrecht University of Kiel and graduated with a Diploma in Biology in 2003. From 2004 until 2006, he undertook research in complex disease genetics for a ''Doctor rerum naturalium'' at the Institute of Clinical Molecular Biology under the supervision of Stefan Schreiber and Thomas C.G. Bosch. His dissertation was titled "A systematic genome-wide association analysis for Inflamm ...
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Geneticist
A geneticist is a biologist or physician who studies genetics, the science of genes, heredity, and variation of organisms. A geneticist can be employed as a scientist or a lecturer. Geneticists may perform general research on genetic processes or develop genetic technologies to aid in the pharmaceutical or and agriculture industries. Some geneticists perform experiments in model organisms such as ''Drosophila'', ''C. elegans'', zebrafish, rodents or humans and analyze data to interpret the inheritance of biological traits. A basic science geneticist is a scientist who usually has earned a PhD in genetics and undertakes research and/or lectures in the field. A medical geneticist is a physician who has been trained in medical genetics as a specialization and evaluates, diagnoses, and manages patients with hereditary conditions or congenital malformations; and provides genetic risk calculations and mutation analysis. Education Geneticists participate in courses from many are ...
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Genetics
Genetics is the study of genes, genetic variation, and heredity in organisms.Hartl D, Jones E (2005) It is an important branch in biology because heredity is vital to organisms' evolution. Gregor Mendel, a Moravian Augustinian friar working in the 19th century in Brno, was the first to study genetics scientifically. Mendel studied "trait inheritance", patterns in the way traits are handed down from parents to offspring over time. He observed that organisms (pea plants) inherit traits by way of discrete "units of inheritance". This term, still used today, is a somewhat ambiguous definition of what is referred to as a gene. Trait inheritance and molecular inheritance mechanisms of genes are still primary principles of genetics in the 21st century, but modern genetics has expanded to study the function and behavior of genes. Gene structure and function, variation, and distribution are studied within the context of the cell, the organism (e.g. dominance), and within the ...
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Kiel University
Kiel University, officially the Christian-Albrecht University of Kiel, (german: Christian-Albrechts-Universität zu Kiel, abbreviated CAU, known informally as Christiana Albertina) is a university in the city of Kiel, Germany. It was founded in 1665 as the ''Academia Holsatorum Chiloniensis'' by Christian Albert, Duke of Holstein-Gottorp and has approximately 27,000 students today. Kiel University is the largest, oldest, and most prestigious in the state of Schleswig-Holstein. Until 1864/66 it was not only the northernmost university in Germany but at the same time the 2nd largest university of Denmark. Faculty, alumni, and researchers of the Kiel University have won 12 Nobel Prizes. Kiel University has been a member of the German Universities Excellence Initiative since 2006. The Cluster of Excellence The Future Ocean, which was established in cooperation with the GEOMAR Helmholtz Centre for Ocean Research Kiel in 2006, is internationally recognized. The second Cluster of Excel ...
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University Medical Center Schleswig Holstein
The University Medical Center Schleswig-Holstein (German: Universitätsklinikum Schleswig-Holstein, abbreviated as UKSH) is a university hospital, located in Kiel and Lübeck in the German state of Schleswig-Holstein. Its aim is to ensure medical care in Schleswig-Holstein. History The University Medical Center Schleswig-Holstein is the result of a merger between the university hospitals in Kiel and Lübeck in 2003. The administrative offices are located in Lübeck. The UKSH works with the University of Kiel and the University of Lübeck, whose students in the faculties of medicine and dentistry (only in Kiel) are trained at the UKSH. Both locations have training opportunities for medical professions, such as nurses and medical laboratory scientists. The Faculty of Medicine at the University of Kiel was one of the founding faculties of the university in 1665. There has been a medical facility on the Lübeck campus since 1912. University hospitals in Schleswig-Holstein are asso ...
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Geneticist
A geneticist is a biologist or physician who studies genetics, the science of genes, heredity, and variation of organisms. A geneticist can be employed as a scientist or a lecturer. Geneticists may perform general research on genetic processes or develop genetic technologies to aid in the pharmaceutical or and agriculture industries. Some geneticists perform experiments in model organisms such as ''Drosophila'', ''C. elegans'', zebrafish, rodents or humans and analyze data to interpret the inheritance of biological traits. A basic science geneticist is a scientist who usually has earned a PhD in genetics and undertakes research and/or lectures in the field. A medical geneticist is a physician who has been trained in medical genetics as a specialization and evaluates, diagnoses, and manages patients with hereditary conditions or congenital malformations; and provides genetic risk calculations and mutation analysis. Education Geneticists participate in courses from many are ...
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Molecular Medicine
Molecular medicine is a broad field, where physical, chemical, biological, bioinformatics and medical techniques are used to describe molecular structures and mechanisms, identify fundamental molecular and genetic errors of disease, and to develop molecular interventions to correct them. The molecular medicine perspective emphasizes cellular and molecular phenomena and interventions rather than the previous conceptual and observational focus on patients and their organs. History In November 1949, with the seminal paper, " Sickle Cell Anemia, a Molecular Disease", in ''Science'' magazine, Linus Pauling, Harvey Itano and their collaborators laid the groundwork for establishing the field of molecular medicine. In 1956, Roger J. Williams wrote ''Biochemical Individuality'', a prescient book about genetics, prevention and treatment of disease on a molecular basis, and nutrition which is now variously referred to as individualized medicine and orthomolecular medicine. Another paper in ...
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Genome-wide Association Study
In genomics, a genome-wide association study (GWA study, or GWAS), also known as whole genome association study (WGA study, or WGAS), is an observational study of a genome-wide set of Single-nucleotide polymorphism, genetic variants in different individuals to see if any variant is associated with a trait. GWA studies typically focus on associations between single-nucleotide polymorphisms (SNPs) and traits like major human diseases, but can equally be applied to any other genetic variants and any other organisms. When applied to human data, GWA studies compare the DNA of participants having varying phenotypes for a particular trait or disease. These participants may be people with a disease (cases) and similar people without the disease (controls), or they may be people with different phenotypes for a particular trait, for example blood pressure. This approach is known as phenotype-first, in which the participants are classified first by their clinical manifestation(s), as oppose ...
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Microbiome
A microbiome () is the community of microorganisms that can usually be found living together in any given habitat. It was defined more precisely in 1988 by Whipps ''et al.'' as "a characteristic microbial community occupying a reasonably well-defined habitat which has distinct physio-chemical properties. The term thus not only refers to the microorganisms involved but also encompasses their theatre of activity". In 2020, an international panel of experts published the outcome of their discussions on the definition of the microbiome. They proposed a definition of the microbiome based on a revival of the "compact, clear, and comprehensive description of the term" as originally provided by Whipps ''et al.'', but supplemented with two explanatory paragraphs. The first explanatory paragraph pronounces the dynamic character of the microbiome, and the second explanatory paragraph clearly separates the term ''microbiota'' from the term ''microbiome''. The microbiota consists of all ...
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Bioinformatics
Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combines biology, chemistry, physics, computer science, information engineering, mathematics and statistics to analyze and interpret the biological data. Bioinformatics has been used for '' in silico'' analyses of biological queries using computational and statistical techniques. Bioinformatics includes biological studies that use computer programming as part of their methodology, as well as specific analysis "pipelines" that are repeatedly used, particularly in the field of genomics. Common uses of bioinformatics include the identification of candidates genes and single nucleotide polymorphisms (SNPs). Often, such identification is made with the aim to better understand the genetic basis of disease, unique adaptations, desirable properties (e ...
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Stefan Schreiber
Stefan may refer to: * Stefan (given name) * Stefan (surname) * Ștefan, a Romanian given name and a surname * Štefan, a Slavic given name and surname * Stefan (footballer) (born 1988), Brazilian footballer * Stefan Heym, pseudonym of German writer Helmut Flieg (1913–2001) * Stefan (honorific), a Serbian title * ''Stefan'' (album), a 1987 album by Dennis González See also * Stefan number, a dimensionless number used in heat transfer * Sveti Stefan or Saint Stefan, a small islet in Montenegro * Stefanus (other) Stefanus may refer to: * A variation of the given name Stephen, particularly in regard to: ** Saint Stephen, first martyr of Christianity * St. Stefanus, Ghent, a Catholic church in Belgium dedicated to Saint Stephen * Stefanus Prize, a human righ ...
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Thomas C
Thomas may refer to: People * List of people with given name Thomas * Thomas (name) * Thomas (surname) * Saint Thomas (other) * Thomas Aquinas (1225–1274) Italian Dominican friar, philosopher, and Doctor of the Church * Thomas the Apostle * Thomas (bishop of the East Angles) (fl. 640s–650s), medieval Bishop of the East Angles * Thomas (Archdeacon of Barnstaple) (fl. 1203), Archdeacon of Barnstaple * Thomas, Count of Perche (1195–1217), Count of Perche * Thomas (bishop of Finland) (1248), first known Bishop of Finland * Thomas, Earl of Mar (1330–1377), 14th-century Earl, Aberdeen, Scotland Geography Places in the United States * Thomas, Illinois * Thomas, Indiana * Thomas, Oklahoma * Thomas, Oregon * Thomas, South Dakota * Thomas, Virginia * Thomas, Washington * Thomas, West Virginia * Thomas County (other) * Thomas Township (other) Elsewhere * Thomas Glacier (Greenland) Arts, entertainment, and media * ''Thomas'' (Burton novel) 1969 novel ...
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