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Anders Krogh
Anders Krogh is a bioinformatician at the University of Copenhagen, where he leads the university's bioinformatics center. He is known for his pioneering work on the use of hidden Markov models in bioinformatics (together with David Haussler), and is co-author of a widely used textbook in bioinformatics. In addition, he also co-authored one of the early textbooks on neural networks.Introduction to the Theory of Neural Computation (Santa Fe Institute Studies in the Sciences of Complexity). (1991) John A. Hertz, Richard G. Palmer, Anders Krogh, Westview Press His current research interests include promoter analysis, non-coding RNA, gene prediction and protein structure prediction. In 2017, Krogh was elected a Fellow of the International Society for Computational Biology (ISCB). See also *ELIXIR ELIXIR (the European life-sciences Infrastructure for biological Information) is an initiative that will allow life science laboratories across Europe to share and store their res ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Promoter (biology)
In genetics, a promoter is a sequence of DNA to which proteins bind to initiate transcription of a single RNA transcript from the DNA downstream of the promoter. The RNA transcript may encode a protein (mRNA), or can have a function in and of itself, such as tRNA or rRNA. Promoters are located near the transcription start sites of genes, upstream on the DNA (towards the 5' region of the sense strand). Promoters can be about 100–1000 base pairs long, the sequence of which is highly dependent on the gene and product of transcription, type or class of RNA polymerase recruited to the site, and species of organism. Promoters control gene expression in bacteria and eukaryotes. RNA polymerase must attach to DNA near a gene for transcription to occur. Promoter DNA sequences provide an enzyme binding site. The -10 sequence is TATAAT. -35 sequences are conserved on average, but not in most promoters. Artificial promoters with conserved -10 and -35 elements transcribe more slowly. All D ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Danish Bioinformaticians
Danish may refer to: * Something of, from, or related to the country of Denmark People * A national or citizen of Denmark, also called a "Dane," see Demographics of Denmark * Culture of Denmark * Danish people or Danes, people with a Danish ancestral or ethnic identity * A member of the Danes, a Germanic tribe * Danish (name), a male given name and surname Language * Danish language, a North Germanic language used mostly in Denmark and Northern Germany * Danish tongue or Old Norse, the parent language of all North Germanic languages Food * Danish cuisine * Danish pastry, often simply called a "Danish" See also * Dane (other) * * Gdańsk * List of Danes * Languages of Denmark The Kingdom of Denmark has only one official language, Danish, the national language of the Danish people, but there are several minority languages spoken, namely Faroese, German, and Greenlandic. A large majority (about 86%) of Danes also s ... {{disambiguation Language a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Living People
Related categories * :Year of birth missing (living people) / :Year of birth unknown * :Date of birth missing (living people) / :Date of birth unknown * :Place of birth missing (living people) / :Place of birth unknown * :Year of death missing / :Year of death unknown * :Date of death missing / :Date of death unknown * :Place of death missing / :Place of death unknown * :Missing middle or first names See also * :Dead people * :Template:L, which generates this category or death years, and birth year and sort keys. : {{DEFAULTSORT:Living people 21st-century people People by status ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
ELIXIR
ELIXIR (the European life-sciences Infrastructure for biological Information) is an initiative that will allow life science laboratories across Europe to share and store their research data as part of an organised network. Its goal is to bring together Europe’s research organisations and data centres to help coordinate the collection, quality control and storage of large amounts of biological data produced by life science experiments. ELIXIR aims to ensure that biological data is integrated into a federated system easily accessible by the scientific community. Mission ELIXIR's mission is to build a sustainable European infrastructure for biological information, supporting life science research and its translation to medicine and the environment, the bio-industries and society. The results from biological experiments produce vast amounts of results that are stored as data using computer software. European countries have invested heavily in research that produces, analyses and ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
International Society For Computational Biology
The International Society for Computational Biology (ISCB) is a scholarly society for researchers in computational biology and bioinformatics. The society was founded in 1997 to provide a stable financial home for the Intelligent Systems for Molecular Biology (ISMB) conference and has grown to become a larger society working towards advancing understanding of living systems through computation and for communicating scientific advances worldwide. In addition to ISMB, the society also organizes a growing number of smaller, more regionally or topically focused conferences and presents a number of annual scientific achievement awards, including the Overton Prize and the ISCB Senior Scientist Awards. Overview Society membership reflects commitment toward the advancement of computational biology. The ISCB is an international non-profit organization whose members come from the global bioinformatics and computational biology communities. The ISCB serves its global membership by providing ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Protein Structure
Protein structure is the three-dimensional arrangement of atoms in an amino acid-chain molecule. Proteins are polymers specifically polypeptides formed from sequences of amino acids, the monomers of the polymer. A single amino acid monomer may also be called a ''residue'' indicating a repeating unit of a polymer. Proteins form by amino acids undergoing condensation reactions, in which the amino acids lose one water molecule per reaction in order to attach to one another with a peptide bond. By convention, a chain under 30 amino acids is often identified as a peptide, rather than a protein. To be able to perform their biological function, proteins fold into one or more specific spatial conformations driven by a number of non-covalent interactions such as hydrogen bonding, ionic interactions, Van der Waals forces, and hydrophobic packing. To understand the functions of proteins at a molecular level, it is often necessary to determine their three-dimensional structure. This is t ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Gene Prediction
In computational biology, gene prediction or gene finding refers to the process of identifying the regions of genomic DNA that encode genes. This includes protein-coding genes as well as RNA genes, but may also include prediction of other functional elements such as regulatory regions. Gene finding is one of the first and most important steps in understanding the genome of a species once it has been sequenced. In its earliest days, "gene finding" was based on painstaking experimentation on living cells and organisms. Statistical analysis of the rates of homologous recombination of several different genes could determine their order on a certain chromosome, and information from many such experiments could be combined to create a genetic map specifying the rough location of known genes relative to each other. Today, with comprehensive genome sequence and powerful computational resources at the disposal of the research community, gene finding has been redefined as a largely computatio ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Non-coding RNA
A non-coding RNA (ncRNA) is a functional RNA molecule that is not translated into a protein. The DNA sequence from which a functional non-coding RNA is transcribed is often called an RNA gene. Abundant and functionally important types of non-coding RNAs include transfer RNAs (tRNAs) and ribosomal RNAs (rRNAs), as well as small RNAs such as microRNAs, siRNAs, piRNAs, snoRNAs, snRNAs, exRNAs, scaRNAs and the long ncRNAs such as Xist and HOTAIR. The number of non-coding RNAs within the human genome is unknown; however, recent transcriptomic and bioinformatic studies suggest that there are thousands of non-coding transcripts. Many of the newly identified ncRNAs have not been validated for their function. There is no consensus in the literature on how much of non-coding transcription is functional. Some researchers have argued that many ncRNAs are non-functional (sometimes referred to as "junk RNA"), spurious transcriptions. Others, however, disagree, arguing instead that many ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
David Haussler
David Haussler (born 1953) is an American bioinformatician known for his work leading the team that assembled the first human genome sequence in the race to complete the Human Genome Project and subsequently for comparative genome analysis that deepens understanding the molecular function and evolution of the genome. Haussler was elected a member of the National Academy of Engineering in 2018 for developments in computational learning theory and bioinformatics, including first assembly of the human genome, its analysis, and data sharing. He is a distinguished professor of biomolecular engineering and founding scientific director of the UC Santa Cruz Genomics Institute at the University of California, Santa Cruz, director of the California Institute for Quantitative Biosciences (QB3) on the UC Santa Cruz campus, and a consulting professor at the Stanford University School of Medicine and the UC San Francisco Biopharmaceutical Sciences Department. Education Haussler studied art ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
University Of Copenhagen
The University of Copenhagen ( da, Københavns Universitet, KU) is a prestigious public university, public research university in Copenhagen, Copenhagen, Denmark. Founded in 1479, the University of Copenhagen is the second-oldest university in Scandinavia after Uppsala University, and ranks as one of the top universities in the Nordic countries, Europe and the world. Its establishment sanctioned by Pope Sixtus IV, the University of Copenhagen was founded by Christian I of Denmark as a Catholic teaching institution with a predominantly Theology, theological focus. In 1537, it was re-established by King Christian III as part of the Lutheran Reformation. Up until the 18th century, the university was primarily concerned with educating clergymen. Through various reforms in the 18th and 19th century, the University of Copenhagen was transformed into a modern, Secularism, secular university, with science and the humanities replacing theology as the main subjects studied and taught. Th ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Bioinformatics Centre (Copenhagen University)
The Bioinformatics Centre is an interdisciplinary research in bioinformatics at the University of Copenhagen (UCPH). The centre is housed in the Section for Computational and RNA Biology at the Department of Biology within the Faculty of Science. Programmes The Bioinformatics Centre is in charge of a masters program in bioinformatics. Organisation There are four different subgroups in the center, each focussing on different topics: * Micro-RNA group: micro-RNA's are small RNA molecules with important roles in regulation of gene expression. The group analyses the biology of micro-RNA's using computational methods and develop tools that are useful for experimental biologists. * Non-coding RNA group: Many RNA molecules play a functional role in the cell that is different from the classic role of serving as a template for protein synthesis. The group works on secondary structure prediction and multiple alignment of non-coding RNA's. * Promotor analysis group: The group develops statis ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
