Alternaria Tenuissima
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Alternaria Tenuissima
''Alternaria tenuissima'' is a saprophyte, saprophytic fungi, fungus and opportunistic plant pathogen. It is Cosmopolitan distribution, cosmopolitan in distribution, and can colonize a wide range of plant hosts. Colonies of ''A. tenuissima'' produce chains on agar growth media. The fungus often forms concentric ring patterns on infected plant leaves. This species produces the allergen Alt a 1, one of the most important outdoor seasonal fungal allergens associated with allergy and asthma provocation. In rare circumstances, this species is also known to infect immunosuppressed humans and animals. Growth and morphology Unlike many other species of ''Alternaria'', the conidiophores of ''A. tenuissima'' can develop in darkness after the colony has been exposed to light even very briefly; however its growth is more robust with longer periods of light exposure. After 5–7 days in culture, colonies of ''A. tenuissima'' reach a diameter of 5 cm on Plate count agar, PCA or V-8 agar (v ...
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Christian Gottfried Daniel Nees Von Esenbeck
Christian Gottfried Daniel Nees von Esenbeck (14 February 1776 – 16 March 1858) was a prolific German botanist, physician, zoologist, and natural philosopher. He was a contemporary of Goethe and was born within the lifetime of Linnaeus. He described approximately 7,000 plant species (almost as many as Linnaeus himself). His last official act as president of the German Academy of Natural Scientists Leopoldina was to admit Charles Darwin as a member. He was the author of numerous monographs on botany and zoology. His best-known works deal with fungi. Biography Nees von Esenbeck was born in Schloss Reichenberg near Reichelsheim (Odenwald). He showed an early interest in science and, after receiving his primary education in Darmstadt, he went on to the University of Jena, obtaining his degree in biology (natural history) and medicine in 1800. He practiced as a physician for Francis I (Erbach-Erbach), but he had developed a great interest in botany during his university studies, ...
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Hypha
A hypha (; ) is a long, branching, filamentous structure of a fungus, oomycete, or actinobacterium. In most fungi, hyphae are the main mode of vegetative growth, and are collectively called a mycelium. Structure A hypha consists of one or more cells surrounded by a tubular cell wall. In most fungi, hyphae are divided into cells by internal cross-walls called "septa" (singular septum). Septa are usually perforated by pores large enough for ribosomes, mitochondria, and sometimes nuclei to flow between cells. The major structural polymer in fungal cell walls is typically chitin, in contrast to plants and oomycetes that have cellulosic cell walls. Some fungi have aseptate hyphae, meaning their hyphae are not partitioned by septa. Hyphae have an average diameter of 4–6 µm. Growth Hyphae grow at their tips. During tip growth, cell walls are extended by the external assembly and polymerization of cell wall components, and the internal production of new cell membrane. The S ...
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Tenuazonic Acid
Tenuazonic acid is a mycotoxin produced by ''Alternaria'' species. It is a powerful eukaryotic protein synthesis inhibitor. It is a tetrameric acid that is ubiquitous in biological environments and prevents the release of newly synthesized protein from the ribosome. Its toxicity is the highest among all ''Alternaria'' mycotoxins and has both phytotoxic and cytotoxic properties. In 1991 Tenuazonic acid was reported to inhibit skin tumor promotion in mice.Tenuazonic acid
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Inhibitory properties

Tenuazonic acid (TeA) is a potent and an effective bio-herbicide d ...
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Mycotoxin
A mycotoxin (from the Greek μύκης , "fungus" and τοξίνη , "toxin") is a toxic secondary metabolite produced by organisms of kingdom Fungi and is capable of causing disease and death in both humans and other animals. The term 'mycotoxin' is usually reserved for the toxic chemical products produced by fungi that readily colonize crops. Examples of mycotoxins causing human and animal illness include aflatoxin, citrinin, fumonisins, ochratoxin A, patulin, trichothecenes, zearalenone, and ergot alkaloids such as ergotamine. One mold species may produce many different mycotoxins, and several species may produce the same mycotoxin. Production Most fungi are aerobic (use oxygen) and are found almost everywhere in extremely small quantities due to the diminute size of their spores. They consume organic matter wherever humidity and temperature are sufficient. Where conditions are right, fungi proliferate into colonies and mycotoxin levels become high. The reason for the product ...
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Antibody
An antibody (Ab), also known as an immunoglobulin (Ig), is a large, Y-shaped protein used by the immune system to identify and neutralize foreign objects such as pathogenic bacteria and viruses. The antibody recognizes a unique molecule of the pathogen, called an antigen. Each tip of the "Y" of an antibody contains a paratope (analogous to a lock) that is specific for one particular epitope (analogous to a key) on an antigen, allowing these two structures to bind together with precision. Using this binding mechanism, an antibody can ''tag'' a microbe or an infected cell for attack by other parts of the immune system, or can neutralize it directly (for example, by blocking a part of a virus that is essential for its invasion). To allow the immune system to recognize millions of different antigens, the antigen-binding sites at both tips of the antibody come in an equally wide variety. In contrast, the remainder of the antibody is relatively constant. It only occurs in a few varia ...
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Allergen
An allergen is a type of antigen that produces an abnormally vigorous immune response in which the immune system fights off a perceived threat that would otherwise be harmless to the body. Such reactions are called allergies. In technical terms, an allergen is an antigen that is capable of stimulating a type-I hypersensitivity reaction in atopic individuals through immunoglobulin E (IgE) responses. Most humans mount significant Immunoglobulin E responses only as a defense against parasitic infections. However, some individuals may respond to many common environmental antigens. This hereditary predisposition is called atopy. In atopic individuals, non-parasitic antigens stimulate inappropriate IgE production, leading to type I hypersensitivity. Sensitivities vary widely from one person (or from one animal) to another. A very broad range of substances can be allergens to sensitive individuals. Types of allergens Allergens can be found in a variety of sources, such as dust mite e ...
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Alternariosis
Alternariosis is an infection by ''Alternaria'', presenting cutaneously as focal, ulcerated papules and plaques. Treatment with itraconazole has been reported. See also * Skin lesion A skin condition, also known as cutaneous condition, is any medical condition that affects the integumentary system—the organ system that encloses the body and includes skin, nails, and related muscle and glands. The major function of this s ... References External links Mycosis-related cutaneous conditions {{Cutaneous-infection-stub ...
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Subcutaneous Tissue
The subcutaneous tissue (), also called the hypodermis, hypoderm (), subcutis, superficial fascia, is the lowermost layer of the integumentary system in vertebrates. The types of cells found in the layer are fibroblasts, adipose cells, and macrophages. The subcutaneous tissue is derived from the mesoderm, but unlike the dermis, it is not derived from the mesoderm's dermatome region. It consists primarily of loose connective tissue, and contains larger blood vessels and nerves than those found in the dermis. It is a major site of fat storage in the body. In arthropods, a hypodermis can refer to an epidermal layer of cells that secretes the chitinous cuticle. The term also refers to a layer of cells lying immediately below the epidermis of plants. Structure * Fibrous bands anchoring the skin to the deep fascia * Collagen and elastin fibers attaching it to the dermis * Fat is absent from the eyelids, clitoris, penis, much of pinna, and scrotum * Blood vessels on route to the der ...
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Cutaneous
Skin is the layer of usually soft, flexible outer tissue covering the body of a vertebrate animal, with three main functions: protection, regulation, and sensation. Other animal coverings, such as the arthropod exoskeleton, have different developmental origin, structure and chemical composition. The adjective cutaneous means "of the skin" (from Latin ''cutis'' 'skin'). In mammals, the skin is an organ of the integumentary system made up of multiple layers of ectodermal tissue and guards the underlying muscles, bones, ligaments, and internal organs. Skin of a different nature exists in amphibians, reptiles, and birds. Skin (including cutaneous and subcutaneous tissues) plays crucial roles in formation, structure, and function of extraskeletal apparatus such as horns of bovids (e.g., cattle) and rhinos, cervids' antlers, giraffids' ossicones, armadillos' osteoderm, and os penis/os clitoris. All mammals have some hair on their skin, even marine mammals like whales, dolphins, a ...
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Alternaria Alternata
''Alternaria alternata'' is a fungus which has been recorded causing leaf spot and other diseases on over 380 host species of plant. It is an opportunistic pathogen on numerous hosts causing leaf spots, rots and blights on many plant parts. It can also cause upper respiratory tract infections and asthma in humans with compromised immunity. Hosts and symptoms ''Alternaria alternata'' has many different hosts depending on its forma specialis. In this review, only ''Alternaria alternata'' f. sp. ''lycopersici'' (AAL) is going to be assessed. This pathogen infects only certain cultivars of tomato plants and is often referred to as Alternaria stem canker of tomato. AAL's main symptom is cankers in the stem. It resides in seeds and seedlings, and is often spread by spores as they become airborne and land on plants. It can also spread throughout other plants. Under severe infection, lesions enlarge and become coalesced causing blighting of the leaves. This symptom progression occur ...
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Conidium
A conidium ( ; ), sometimes termed an asexual chlamydospore or chlamydoconidium (), is an asexual, non-motile spore of a fungus. The word ''conidium'' comes from the Ancient Greek word for dust, ('). They are also called mitospores due to the way they are generated through the cellular process of mitosis. The two new haploid cells are genetically identical to the haploid parent, and can develop into new organisms if conditions are favorable, and serve in biological dispersal. Asexual reproduction in ascomycetes (the phylum Ascomycota) is by the formation of conidia, which are borne on specialized stalks called conidiophores. The morphology of these specialized conidiophores is often distinctive between species and, before the development of molecular techniques at the end of the 20th century, was widely used for identification of (''e.g.'' ''Metarhizium'') species. The terms microconidia and macroconidia are sometimes used. Conidiogenesis There are two main types of co ...
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Elias Magnus Fries
Elias Magnus Fries (15 August 1794 – 8 February 1878) was a Swedish mycologist and botanist. Career Fries was born at Femsjö (Hylte Municipality), Småland, the son of the pastor there. He attended school in Växjö. He acquired an extensive knowledge of flowering plants from his father. In 1811 Fries entered Lund University where he obtained a doctorate in 1814. In the same year he was appointed an associate professorship in botany. He was elected a member of the Royal Swedish Academy of Sciences, and in 1824, became a full professor. In 1834 he became Borgström professor (Swed. ''Borgströmianska professuren'', a chair endowed by Erik Eriksson Borgström, 1708–1770) in applied economics at Uppsala University. The position was changed to "professor of botany and applied economics" in 1851. He was elected a Foreign Honorary Member of the American Academy of Arts and Sciences in 1849. That year he was also appointed director of the Uppsala University Botanica ...
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