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Alfred Bertheim
Alfred Bertheim (17 April 1879 – 17 August 1914) was a German chemist, best known for his research on arsenic compounds with Paul Ehrlich. Bertheim was born in 1879 in Berlin and studied chemistry in Strasbourg and Berlin, where he gained his doctorate in 1901, with a thesis "Ueber die fluorescierende Verbindung aus Chlor-alpha-naphtochinonacetessigeste". He served as an assistant to Privy Councilor Liebermann and Professor Rosenheim in Berlin. In 1904 and 1905, he worked as a manufacturing chemist in Bitterfeld before moving to the Georg-Speyer-Haus in 1906. There, together with Paul Ehrlich, he elucidated the chemical constitution of atoxyl and synthesized innumerable arsenobenzene compounds. He was also responsible for the synthesis of Salvarsan Arsphenamine, also known as Salvarsan or compound 606, is a drug that was introduced at the beginning of the 1910s as the first effective treatment for syphilis, relapsing fever, and African trypanosomiasis. This organoarsenic comp ...
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Chemist
A chemist (from Greek ''chēm(ía)'' alchemy; replacing ''chymist'' from Medieval Latin ''alchemist'') is a scientist trained in the study of chemistry. Chemists study the composition of matter and its properties. Chemists carefully describe the properties they study in terms of quantities, with detail on the level of molecules and their component atoms. Chemists carefully measure substance proportions, chemical reaction rates, and other chemical properties. In Commonwealth English, pharmacists are often called chemists. Chemists use their knowledge to learn the composition and properties of unfamiliar substances, as well as to reproduce and synthesize large quantities of useful naturally occurring substances and create new artificial substances and useful processes. Chemists may specialize in any number of subdisciplines of chemistry. Materials scientists and metallurgists share much of the same education and skills with chemists. The work of chemists is often related to t ...
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Arsenic
Arsenic is a chemical element with the symbol As and atomic number 33. Arsenic occurs in many minerals, usually in combination with sulfur and metals, but also as a pure elemental crystal. Arsenic is a metalloid. It has various allotropes, but only the gray form, which has a metallic appearance, is important to industry. The primary use of arsenic is in alloys of lead (for example, in car batteries and ammunition). Arsenic is a common n-type dopant in semiconductor electronic devices. It is also a component of the III-V compound semiconductor gallium arsenide. Arsenic and its compounds, especially the trioxide, are used in the production of pesticides, treated wood products, herbicides, and insecticides. These applications are declining with the increasing recognition of the toxicity of arsenic and its compounds. A few species of bacteria are able to use arsenic compounds as respiratory metabolites. Trace quantities of arsenic are an essential dietary element in r ...
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Paul Ehrlich
Paul Ehrlich (; 14 March 1854 – 20 August 1915) was a Nobel Prize-winning German physician and scientist who worked in the fields of hematology, immunology, and antimicrobial chemotherapy. Among his foremost achievements were finding a cure for syphilis in 1909 and inventing the precursor technique to Gram staining bacteria. The methods he developed for staining tissue made it possible to distinguish between different types of blood cells, which led to the ability to diagnose numerous blood diseases. His laboratory discovered arsphenamine (Salvarsan), the first effective medicinal treatment for syphilis, thereby initiating and also naming the concept of chemotherapy. Ehrlich popularized the concept of a magic bullet. He also made a decisive contribution to the development of an antiserum to combat diphtheria and conceived a method for standardizing therapeutic serums. In 1908, he received the Nobel Prize in Physiology or Medicine for his contributions to immunology. ...
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Berlin
Berlin ( , ) is the capital and List of cities in Germany by population, largest city of Germany by both area and population. Its 3.7 million inhabitants make it the European Union's List of cities in the European Union by population within city limits, most populous city, according to population within city limits. One of Germany's States of Germany, sixteen constituent states, Berlin is surrounded by the Brandenburg, State of Brandenburg and contiguous with Potsdam, Brandenburg's capital. Berlin's urban area, which has a population of around 4.5 million, is the second most populous urban area in Germany after the Ruhr. The Berlin/Brandenburg Metropolitan Region, Berlin-Brandenburg capital region has around 6.2 million inhabitants and is Metropolitan regions in Germany, Germany's third-largest metropolitan region after the Rhine-Ruhr and Frankfurt Rhine-Main, Rhine-Main regions. Berlin straddles the banks of the Spree (river), Spree, which flows into the Havel (a tributary of ...
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Bitterfeld
Bitterfeld () is a town in the district of Anhalt-Bitterfeld, Saxony-Anhalt, Germany. Since 1 July 2007 it has been part of the town of Bitterfeld-Wolfen. It is situated approximately 25 km south of Dessau, and 30 km northeast of Halle (Saale). At the end of 2016, it had 40,964 inhabitants. History and description The name Bitterfeld most likely comes from the Middle High German words ''bitter'' and ''Feld'' and so means "boggy land". Bitterfeld was built by a colony of Flemish immigrants in 1153. The first documentary mention is from 1224. It was captured by the landgrave of Meissen in 1476, and belonged thenceforth to Saxony, until it was ceded to Prussia in 1815. By 1900, Bitterfeld station was an important junction of the Berlin–Halle and the Magdeburg–Leipzig railways. The population at that time was 11,839; it manufactured drainpipes, paper roofing, and machinery, and had sawmills. There were also several coal mines in the vicinity. Owing to its pleasant ...
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Atoxyl
Arsanilic acid, also known as aminophenyl arsenic acid or aminophenyl arsonic acid, is an organoarsenic compound, an amino derivative of phenylarsonic acid whose amine group is in the 4-position. A crystalline powder introduced medically in the late 19th century as Atoxyl, its sodium salt was used by injection in the early 20th century as the first organic arsenical drug, but it was soon found prohibitively toxic for human use. Arsanilic acid saw long use as a veterinary feed additive promoting growth and to prevent or treat dysentery in poultry and swine. In 2013, its approval by US government as an animal drug was voluntarily withdrawn by its sponsors. Still sometimes used in laboratories, arsanilic acid's legacy is principally through its influence on Paul Ehrlich in launching the antimicrobial chemotherapy approach to treating infectious diseases of humans. Chemistry Synthesis was first reported in 1863 by Antoine Béchamp and became the basis of the Bechamp reaction. The ...
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Salvarsan
Arsphenamine, also known as Salvarsan or compound 606, is a drug that was introduced at the beginning of the 1910s as the first effective treatment for syphilis, relapsing fever, and African trypanosomiasis. This organoarsenic compound was the first modern antimicrobial agent. History Arsphenamine was first synthesized in 1907 in Paul Ehrlich's lab by Alfred Bertheim. The antisyphilitic activity of this compound was discovered by Sahachiro Hata in 1909, during a survey of hundreds of newly synthesized organic arsenical compounds. Ehrlich had theorized that by screening many compounds, a drug could be discovered that would have anti-microbial activity but not kill the human patient. Ehrlich's team began their search for such a " magic bullet" among chemical derivatives of the dangerously toxic drug atoxyl. This project was the first organized team effort to optimize the biological activity of a lead compound through systematic chemical modifications, the basis for nearly all mo ...
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1879 Births
Events January–March * January 1 – The Specie Resumption Act takes effect. The United States Note is valued the same as gold, for the first time since the American Civil War. * January 11 – The Anglo-Zulu War begins. * January 22 – Anglo-Zulu War – Battle of Isandlwana: A force of 1,200 British soldiers is wiped out by over 20,000 Zulu warriors. * January 23 – Anglo-Zulu War – Battle of Rorke's Drift: Following the previous day's defeat, a smaller British force of 140 successfully repels an attack by 4,000 Zulus. * February 3 – Mosley Street in Newcastle upon Tyne (England) becomes the world's first public highway to be lit by the electric incandescent light bulb invented by Joseph Swan. * February 8 – At a meeting of the Royal Canadian Institute, engineer and inventor Sandford Fleming first proposes the global adoption of standard time. * March 3 – United States Geological Survey is founded. * March 11 – ...
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1914 Deaths
This year saw the beginning of what became known as World War I, after Archduke Franz Ferdinand of Austria, heir to the Austrian throne was assassinated by Serbian nationalist Gavrilo Princip. It also saw the first airline to provide scheduled regular commercial passenger services with heavier-than-air aircraft, with the St. Petersburg–Tampa Airboat Line. Events January * January 1 – The St. Petersburg–Tampa Airboat Line in the United States starts services between St. Petersburg and Tampa, Florida, becoming the first airline to provide scheduled regular commercial passenger services with heavier-than-air aircraft, with Tony Jannus (the first federally-licensed pilot) conveying passengers in a Benoist XIV flying boat. Abram C. Pheil, mayor of St. Petersburg, is the first airline passenger, and over 3,000 people witness the first departure. * January 11 – The Sakurajima volcano in Japan begins to erupt, becoming effusive after a very large earthquake ...
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Scientists From Berlin
A scientist is a person who conducts scientific research to advance knowledge in an area of the natural sciences. In classical antiquity, there was no real ancient analog of a modern scientist. Instead, philosophers engaged in the philosophical study of nature called natural philosophy, a precursor of natural science. Though Thales (circa 624-545 BC) was arguably the first scientist for describing how cosmic events may be seen as natural, not necessarily caused by gods,Frank N. Magill''The Ancient World: Dictionary of World Biography'', Volume 1 Routledge, 2003 it was not until the 19th century that the term ''scientist'' came into regular use after it was coined by the theologian, philosopher, and historian of science William Whewell in 1833. In modern times, many scientists have advanced degrees in an area of science and pursue careers in various sectors of the economy such as academia, industry, government, and nonprofit environments.'''' History The role ...
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German Military Personnel Killed In World War I
German(s) may refer to: * Germany (of or related to) **Germania (historical use) * Germans, citizens of Germany, people of German ancestry, or native speakers of the German language ** For citizens of Germany, see also German nationality law **Germanic peoples (Roman times) * German language **any of the Germanic languages * German cuisine, traditional foods of Germany People * German (given name) * German (surname) * Germán, a Spanish name Places * German (parish), Isle of Man * German, Albania, or Gërmej * German, Bulgaria * German, Iran * German, North Macedonia * German, New York, U.S. * Agios Germanos, Greece Other uses * German (mythology), a South Slavic mythological being * Germans (band), a Canadian rock band * "German" (song), a 2019 song by No Money Enterprise * ''The German'', a 2008 short film * "The Germans", an episode of ''Fawlty Towers'' * ''The German'', a nickname for Congolese rebel André Kisase Ngandu See also * Germanic (other) * ...
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