Alexander Fleming Biomedical Sciences Research Center
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Alexander Fleming Biomedical Sciences Research Center
The Biomedical Sciences Research Center "Alexander Fleming" is a non-profit research organisation based in Vari, Athens, Greece. The Center is named after the scientist Alexander Fleming and his widow, Amalia Fleming "created the conditions to set up" this Center.The Fleming Museum of Contemporary Science
fleming.gr. Retrieved 9 April 2020. Since the beginning of its operations in 1998, the Center develops basic as well as translational and applied research programs at the cutting edge of modern biomedical sciences. Currently, the Center hosts 14 research groups distributed in 4 Institutes (Immunology, Molecular Oncology, Molecular Biology and Genetics, Cellular & Developmental Biology). Over the short period since its establishment, BSRC Al. Fleming has gained extensive visibility in the European science arena. Fleming's rese ...
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Vari
Vari ( el, Βάρη) is a southern suburb of Athens and former municipality in East Attica, Greece along the Athens coast. Since the 2011 local government reform it is part of the municipality Vari-Voula-Vouliagmeni, of which it is a municipal unit. nasterjd, on Athena (capital). The municipal unit has an area of 22.633 km2. Geography It lies at the southwestern end of the Mesogeia plain and the southeast shoulder of the Hymettus mountain, near the Saronic Gulf coast. Greek National Road 91 connects Vari with Athens city centre and Sounio. Vari's beach is located in an area called Varkiza, a fishing village that joined the municipality of Vari, in 1997. This particular beach has won the blue flag many years in the past, including 2009. After 1 January 2011 Vari joined Voula and Vouliagmeni, according to Kallikratis regulations, in a joined municipality. Grigoris Konstantellos is the incumbent mayor, elected for a second term at May 26, 2019, for the unified municipality of ...
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Athens
Athens ( ; el, Αθήνα, Athína ; grc, Ἀθῆναι, Athênai (pl.) ) is both the capital and largest city of Greece. With a population close to four million, it is also the seventh largest city in the European Union. Athens dominates and is the capital of the Attica region and is one of the world's oldest cities, with its recorded history spanning over 3,400 years and its earliest human presence beginning somewhere between the 11th and 7th millennia BC. Classical Athens was a powerful city-state. It was a centre for the arts, learning and philosophy, and the home of Plato's Academy and Aristotle's Lyceum. It is widely referred to as the cradle of Western civilization and the birthplace of democracy, largely because of its cultural and political influence on the European continent—particularly Ancient Rome. In modern times, Athens is a large cosmopolitan metropolis and central to economic, financial, industrial, maritime, political and cultural life in Gre ...
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Greece
Greece,, or , romanized: ', officially the Hellenic Republic, is a country in Southeast Europe. It is situated on the southern tip of the Balkans, and is located at the crossroads of Europe, Asia, and Africa. Greece shares land borders with Albania to the northwest, North Macedonia and Bulgaria to the north, and Turkey to the northeast. The Aegean Sea lies to the east of the Geography of Greece, mainland, the Ionian Sea to the west, and the Sea of Crete and the Mediterranean Sea to the south. Greece has the longest coastline on the Mediterranean Basin, featuring List of islands of Greece, thousands of islands. The country consists of nine Geographic regions of Greece, traditional geographic regions, and has a population of approximately 10.4 million. Athens is the nation's capital and List of cities and towns in Greece, largest city, followed by Thessaloniki and Patras. Greece is considered the cradle of Western culture, Western civilization, being the birthplace of Athenian ...
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Alexander Fleming
Sir Alexander Fleming (6 August 1881 – 11 March 1955) was a Scottish physician and microbiologist, best known for discovering the world's first broadly effective antibiotic substance, which he named penicillin. His discovery in 1928 of what was later named benzylpenicillin (or penicillin G) from the mould ''Penicillium rubens'' is described as the "single greatest victory ever achieved over disease." For this discovery, he shared the Nobel Prize in Physiology or Medicine in 1945 with Howard Florey and Ernst Boris Chain. He also discovered the enzyme lysozyme from his nasal discharge in 1922, and along with it a bacterium he named ''Micrococcus Lysodeikticus'', later renamed ''Micrococcus luteus''. Fleming was knighted for his scientific achievements in 1944. In 1999, he was named in ''Time'' magazine's list of the 100 Most Important People of the 20th century. In 2002, he was chosen in the BBC's television poll for determining the 100 Greatest Britons, and in 2009, h ...
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Amalia Fleming
Amalia, Lady Fleming, (née Koutsouri-Vourekas; el, Αμαλία Κουτσούρη-Φλέμινγκ; 28 June 1912 – 26 February 1986) was a Greek physician, bacteriologist, human rights activist and politician. Early life and education Fleming was born in Constantinople, Ottoman Empire (now Istanbul, Turkey), in 1912. Her father was Harikios Koutsouris, a physician."Obituary: Lady Fleming: Greek Patriot and Politician," ''The Times'', 27 February 1986, p. 14. In 1914, with the outbreak of the First World War and the rise of the "racially intolerant Pan-Turkish state",John HaagFleming, Amalia (1912–1986) encyclopedia.com. Retrieved 8 April 2020. with the family home lost and her father's laboratory confiscated, she fled to Athens with her family. She studied medicine, and particularly bacteriology, at the University of Athens. From 1938 to 1944 she worked as a bacteriologist at Athens City Hospital. She married Manoli Vourekas, an architect. Second World War In April 1941 ...
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Expression Profiling
In the field of molecular biology, gene expression profiling is the measurement of the activity (the expression) of thousands of genes at once, to create a global picture of cellular function. These profiles can, for example, distinguish between cells that are actively dividing, or show how the cells react to a particular treatment. Many experiments of this sort measure an entire genome simultaneously, that is, every gene present in a particular cell. Several transcriptomics technologies can be used to generate the necessary data to analyse. DNA microarrays measure the relative activity of previously identified target genes. Sequence based techniques, like RNA-Seq, provide information on the sequences of genes in addition to their expression level. Background Expression profiling is a logical next step after sequencing a genome: the sequence tells us what the cell could possibly do, while the expression profile tells us what it is actually doing at a point in time. Genes con ...
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Flow Cytometry
Flow cytometry (FC) is a technique used to detect and measure physical and chemical characteristics of a population of cells or particles. In this process, a sample containing cells or particles is suspended in a fluid and injected into the flow cytometer instrument. The sample is focused to ideally flow one cell at a time through a laser beam, where the light scattered is characteristic to the cells and their components. Cells are often labeled with fluorescent markers so light is absorbed and then emitted in a band of wavelengths. Tens of thousands of cells can be quickly examined and the data gathered are processed by a computer. Flow cytometry is routinely used in basic research, clinical practice, and clinical trials. Uses for flow cytometry include: * Cell counting * Cell sorting * Determining cell characteristics and function * Detecting microorganisms * Biomarker detection * Protein engineering detection * Diagnosis of health disorders such as blood cancers * Measuring ...
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Protein Chemistry
Molecular biophysics is a rapidly evolving interdisciplinary area of research that combines concepts in physics, chemistry, engineering, mathematics and biology. It seeks to understand biomolecular systems and explain biological function in terms of molecular structure, structural organization, and dynamic behaviour at various levels of complexity (from single molecules to supramolecular structures, viruses and small living systems). This discipline covers topics such as the measurement of molecular forces, molecular associations, allosteric interactions, Brownian motion, and cable theory. Additional areas of study can be found on Outline of Biophysics. The discipline has required development of specialized equipment and procedures capable of imaging and manipulating minute living structures, as well as novel experimental approaches. Overview Molecular biophysics typically addresses biological questions similar to those in biochemistry and molecular biology, seeking to find the ...
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Bioinformatics
Bioinformatics () is an interdisciplinary field that develops methods and software tools for understanding biological data, in particular when the data sets are large and complex. As an interdisciplinary field of science, bioinformatics combines biology, chemistry, physics, computer science, information engineering, mathematics and statistics to analyze and interpret the biological data. Bioinformatics has been used for '' in silico'' analyses of biological queries using computational and statistical techniques. Bioinformatics includes biological studies that use computer programming as part of their methodology, as well as specific analysis "pipelines" that are repeatedly used, particularly in the field of genomics. Common uses of bioinformatics include the identification of candidates genes and single nucleotide polymorphisms (SNPs). Often, such identification is made with the aim to better understand the genetic basis of disease, unique adaptations, desirable properties (e ...
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Animal House
''National Lampoon's Animal House'' is a 1978 American comedy film directed by John Landis and written by Harold Ramis, Douglas Kenney and Chris Miller. It stars John Belushi, Peter Riegert, Tim Matheson, John Vernon, Verna Bloom, Thomas Hulce, Stephen Furst, and Donald Sutherland. The film is about a trouble-making fraternity whose members challenge the authority of the dean of the fictional Faber College. The film was produced by Matty Simmons of '' National Lampoon'' and Ivan Reitman for Universal Pictures. It was inspired by stories written by Miller and published in ''National Lampoon''. The stories were based on Ramis' experience in the Zeta Beta Tau fraternity at Washington University in St. Louis, Miller's Alpha Delta Phi experiences at Dartmouth College in New Hampshire, and producer Reitman's at McMaster University in Hamilton, Ontario. Of the younger lead actors, only the 28-year-old Belushi was an established star, but even he had not yet appeared in a film ...
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Biomedical Research
Medical research (or biomedical research), also known as experimental medicine, encompasses a wide array of research, extending from "basic research" (also called ''bench science'' or ''bench research''), – involving fundamental scientific principles that may apply to a ''preclinical'' understanding – to clinical research, which involves studies of people who may be subjects in clinical trials. Within this spectrum is applied research, or translational research, conducted to expand knowledge in the field of medicine. Both clinical and preclinical research phases exist in the pharmaceutical industry's drug development pipelines, where the clinical phase is denoted by the term ''clinical trial''. However, only part of the clinical or preclinical research is oriented towards a specific pharmaceutical purpose. The need for fundamental and mechanism-based understanding, diagnostics, medical devices, and non-pharmaceutical therapies means that pharmaceutical research i ...
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Medical And Health Organizations Based In Greece
Medicine is the science and practice of caring for a patient, managing the diagnosis, prognosis, prevention, treatment, palliation of their injury or disease, and promoting their health. Medicine encompasses a variety of health care practices evolved to maintain and restore health by the prevention and treatment of illness. Contemporary medicine applies biomedical sciences, biomedical research, genetics, and medical technology to diagnose, treat, and prevent injury and disease, typically through pharmaceuticals or surgery, but also through therapies as diverse as psychotherapy, external splints and traction, medical devices, biologics, and ionizing radiation, amongst others. Medicine has been practiced since prehistoric times, and for most of this time it was an art (an area of skill and knowledge), frequently having connections to the religious and philosophical beliefs of local culture. For example, a medicine man would apply herbs and say prayers for healing, o ...
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