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African Histoplasmosis
African histoplasmosis is a fungal infection caused by ''Histoplasma capsulatum'' var. ''duboisii'', or ''Histoplama duboisii'' (Hcd). Disease has been most often reported in Uganda, Nigeria, Zaire (Democratic Republic of the Congo) and Senegal, as Hcd is exclusive to Africa. In human disease it manifests differently than histoplasmosis (caused by ''Histoplasma capsulatum'', or Hcc), most often involving the skin and bones and rarely involving the lungs. Also unlike Hcc, Hcd has been reported to rarely present in those with HIV, likely due to underreporting. However, this along with the differences in Hcc and Hcd have been disputed. The favored locations of African histoplasmosis are "osteoarticular, ganglionic and pulmonary". Genitourinary skin damage is rare, occurring in only 4-11% patients and typically as a secondary skin invasion in those with disseminated infection. It presents as "localized with isolated skin, bone, or lymph node infections or disseminated with multiple cu ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Histoplasma Duboisii
''Histoplasma duboisii'' is a saprotrophic fungus responsible for the invasive infection known as African histoplasmosis. This species is a close relative of ''Histoplasma capsulatum'', the agent of classical histoplasmosis, and the two occur in similar habitats. ''Histoplasma duboisii'' is restricted to continental Africa and Madagascar, although scattered reports have arisen from other places usually in individuals with an African travel history. Like, ''H. capsulatum'', ''H. duboisii'' is dimorphic – growing as a filamentous fungus at ambient temperature and a yeast at body temperature. It differs morphologically from ''H. capsulatum'' by the typical production of a large-celled yeast form. Both agents cause similar forms of disease, although ''H. duboisii'' predominantly causes cutaneous and subcutaneous disease in humans and non-human primates. The agent responds to many antifungal drug therapies used to treat serious fungal diseases. History Histoplasmosis was first repo ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Liver
The liver is a major Organ (anatomy), organ only found in vertebrates which performs many essential biological functions such as detoxification of the organism, and the Protein biosynthesis, synthesis of proteins and biochemicals necessary for digestion and growth. In humans, it is located in the quadrant (anatomy), right upper quadrant of the abdomen, below the thoracic diaphragm, diaphragm. Its other roles in metabolism include the regulation of Glycogen, glycogen storage, decomposition of red blood cells, and the production of hormones. The liver is an accessory digestive organ that produces bile, an alkaline fluid containing cholesterol and bile acids, which helps the fatty acid degradation, breakdown of fat. The gallbladder, a small pouch that sits just under the liver, stores bile produced by the liver which is later moved to the small intestine to complete digestion. The liver's highly specialized biological tissue, tissue, consisting mostly of hepatocytes, regulates a w ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Fistulization
A fistula (plural: fistulas or fistulae ; from Latin ''fistula'', "tube, pipe") in anatomy is an abnormal connection between two hollow spaces (technically, two epithelialized surfaces), such as blood vessels, intestines, or other hollow organs. Types of fistula can be described by their location. Anal fistulas connect between the anal canal and the perianal skin. Anovaginal or rectovaginal fistulas occur when a hole develops between the anus or rectum and the vagina. Colovaginal fistulas occur between the colon and the vagina. Urinary tract fistulas are abnormal openings within the urinary tract or an abnormal connection between the urinary tract and another organ such as between the bladder and the uterus in a vesicouterine fistula, between the bladder and the vagina in a vesicovaginal fistula, and between the urethra and the vagina in urethrovaginal fistula. When occurring between two parts of the intestine, it is known as an enteroenteral fistula, between the small intesti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Cold Abscess
Cold abscess refers to an abscess that lacks the intense inflammation usually associated with infection. This may be associated with infections due to bacteria like ''Mycobacterium tuberculosis'', the cause of tuberculosis, and fungi like those from the genus ''Blastomyces'', which cause blastomycosis, that do not tend to stimulate acute inflammation. Alternatively, cold abscesses are typical in persons with hyperimmunoglobulin E syndrome, even when infected with an organism like ''Staphylococcus aureus'' that causes abscesses with inflammation in others. Signs of acute inflammation are absent, so the abscess is not hot and red as in a typical abscess filled with pus. Cold abscesses are generally painless cysts that may be subcutaneous, ocular, or in deep tissue such as the spine. See also * Tuberculous cervical lymphadenitis The disease mycobacterial cervical lymphadenitis, also known as scrofula and historically as king's evil, involves a lymphadenitis of the cervical lymph n ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Ulcer
An ulcer is a discontinuity or break in a bodily membrane that impedes normal function of the affected organ. According to Robbins's pathology, "ulcer is the breach of the continuity of skin, epithelium or mucous membrane caused by sloughing out of inflamed necrotic tissue." Common forms of ulcers recognized in medicine include: * Ulcer (dermatology), a discontinuity of the skin or a break in the skin. ** Pressure ulcers, also known as bedsores ** Genital ulcer, an ulcer located on the genital area ** Ulcerative dermatitis, a skin disorder associated with bacterial growth often initiated by self-trauma ** Anal fissure, a.k.a. an ulcer or tear near the anus or within the rectum ** Diabetic foot ulcer, a major complication of the diabetic foot * Corneal ulcer, an inflammatory or infective condition of the cornea * Mouth ulcer, an open sore inside the mouth. ** Aphthous ulcer, a specific type of oral ulcer also known as a canker sore * Peptic ulcer, a discontinuity of the gastroint ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Papule
A papule is a small, well-defined bump in the skin. It may have a rounded, pointed or flat top, and may have a dip. It can appear with a stalk, be thread-like or look warty. It can be soft or firm and its surface may be rough or smooth. Some have crusts or scales. A papule can be flesh colored, yellow, white, brown, red, blue or purplish. There may be just one or many, and they may occur irregularly in different parts of the body or appear in clusters. It does not contain fluid but may progress to a pustule or vesicle. A papule is smaller than a nodule; it can be as tiny as a pinhead and is typically less than 1 cm in width, according to some sources, and 0.5 cm according to others. When merged together, it appears as a plaque. Its color might indicate its cause, such as white in milia, red in eczema, yellowish in xanthoma and black in melanoma. They may open when scratched and become infected and crusty. Definition A papule is a small, well-defined bump in the s ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Nodule (medicine)
In medicine, nodules are small firm lumps, usually greater than 1 cm in diameter. If filled with fluid they are referred to as cysts. Smaller (less than 0.5 cm) raised soft tissue bumps may be termed papules. The evaluation of a skin nodule includes a description of its appearance, its location, how it feels to touch and any associated symptoms which may give clues to an underlying medical condition. Nodules in skin include dermatofibroma and pyogenic granuloma. Nodules may form on tendons and muscles in response to injury, and are frequently found on vocal cords. They may occur in organs such as the lung, or thyroid, or be a sign in other medical conditions such as rheumatoid arthritis. Characteristics Nodules are small firm lumps usually greater than 1 cm in diameter, found in skin and other organs. If filled with fluid they are usually softer and referred to as cysts. Smaller (less than 0.5 cm) raised soft tissue bumps may be termed papules. Evaluation The evaluation of a ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Visceral Organ
In biology, an organ is a collection of tissues joined in a structural unit to serve a common function. In the hierarchy of life, an organ lies between tissue and an organ system. Tissues are formed from same type cells to act together in a function. Tissues of different types combine to form an organ which has a specific function. The intestinal wall for example is formed by epithelial tissue and smooth muscle tissue. Two or more organs working together in the execution of a specific body function form an organ system, also called a biological system or body system. An organ's tissues can be broadly categorized as parenchyma, the functional tissue, and stroma, the structural tissue with supportive, connective, or ancillary functions. For example, the gland's tissue that makes the hormones is the parenchyma, whereas the stroma includes the nerves that innervate the parenchyma, the blood vessels that oxygenate and nourish it and carry away its metabolic wastes, and the connecti ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Spleen
The spleen is an organ found in almost all vertebrates. Similar in structure to a large lymph node, it acts primarily as a blood filter. The word spleen comes .σπλήν Henry George Liddell, Robert Scott, ''A Greek-English Lexicon'', on Perseus Digital Library The spleen plays very important roles in regard to s (erythrocytes) and the . It removes old red blood cells and holds a reserve of blood, which can be valuable in case of |
Lymph Node
A lymph node, or lymph gland, is a kidney-shaped organ of the lymphatic system and the adaptive immune system. A large number of lymph nodes are linked throughout the body by the lymphatic vessels. They are major sites of lymphocytes that include B and T cells. Lymph nodes are important for the proper functioning of the immune system, acting as filters for foreign particles including cancer cells, but have no detoxification function. In the lymphatic system a lymph node is a secondary lymphoid organ. A lymph node is enclosed in a fibrous capsule and is made up of an outer cortex and an inner medulla. Lymph nodes become inflamed or enlarged in various diseases, which may range from trivial throat infections to life-threatening cancers. The condition of lymph nodes is very important in cancer staging, which decides the treatment to be used and determines the prognosis. Lymphadenopathy refers to glands that are enlarged or swollen. When inflamed or enlarged, lymph nodes can be ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Uganda
}), is a landlocked country in East Africa East Africa, Eastern Africa, or East of Africa, is the eastern subregion of the African continent. In the United Nations Statistics Division scheme of geographic regions, 10-11-(16*) territories make up Eastern Africa: Due to the historical .... The country is bordered to the east by Kenya, to the north by South Sudan, to the west by the Democratic Republic of the Congo, to the south-west by Rwanda, and to the south by Tanzania. The southern part of the country includes a substantial portion of Lake Victoria, shared with Kenya and Tanzania. Uganda is in the African Great Lakes region. Uganda also lies within the Nile, Nile basin and has a varied but generally a modified equatorial climate. It has a population of around 49 million, of which 8.5 million live in the Capital city, capital and largest city of Kampala. Uganda is named after the Buganda kingdom, which encompasses a large portion of the south of the country, includi ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
Subcutaneous Abscess
A subcutaneous abscess is an abscess located in the subcutaneous tissue (also hypodermis). The abscess is formed due to a hypodermal infection by a bacterium, a fungus or a parasite. Typically, this kind of abscess needs drainage, usually for a minimum of 24 hours, by means of gauze packing or a Penrose drain. Types * neutrophilic abscess * eosinophilic abscess ** eosinophilic granulomatous abscess Eosinophilic (Greek suffix -phil-, meaning ''loves eosin'') is the staining of tissues, cells, or organelles after they have been washed with eosin, a dye. Eosin is an acidic dye for staining cell cytoplasm, collagen, and muscle fibers. '' ... References Cutaneous lesion {{med-sign-stub ... [...More Info...] [...Related Items...] OR: [Wikipedia] [Google] [Baidu] |
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