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Ataxia–telangiectasia
Ataxia–telangiectasia (AT or A–T), also referred to as ataxia–telangiectasia syndrome or Louis–Bar syndrome, is a rare, neurodegenerative, autosomal recessive disease causing severe disability. Ataxia refers to poor coordination and telangiectasia to small dilated blood vessels, both of which are hallmarks of the disease. A–T affects many parts of the body: * It impairs certain areas of the brain including the cerebellum, causing difficulty with movement and coordination. * It weakens the immune system, causing a predisposition to infection. * It prevents repair of broken DNA, increasing the risk of cancer. Symptoms most often first appear in early childhood (the toddler stage) when children begin to sit or walk. Though they usually start walking at a normal age, they wobble or sway when walking, standing still or sitting. In late pre-school and early school age, they develop difficulty moving their eyes in a natural manner from one place to the next (oculomotor apraxia) ...
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IBM Personal Computer/AT
The IBM Personal Computer/AT (model 5170, abbreviated as IBM AT or PC/AT) was released in 1984 as the fourth model in the IBM Personal Computer line, following the IBM PC/XT and its IBM Portable PC variant. It was designed around the Intel 80286 microprocessor. Name IBM did not specify an expanded form of "AT" on the machine, press releases, brochures or documentation, but some sources expand the term as "Advanced Technology", including at least one internal IBM document. History IBM's 1984 introduction of the AT was seen as an unusual move for the company, which typically waited for competitors to release new products before producing its own models. At $4,000–6,000, it was only slightly more expensive than considerably slower IBM models. The announcement surprised rival executives, who admitted that matching IBM's prices would be difficult. No major competitor showed a comparable computer at COMDEX Las Vegas that year. Features The AT is IBM PC compatible, with the mo ...
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Appalachian Trail
The Appalachian Trail (also called the A.T.), is a hiking trail in the Eastern United States, extending almost between Springer Mountain in Georgia and Mount Katahdin in Maine, and passing through 14 states.Gailey, Chris (2006)"Appalachian Trail FAQs" Outdoors.org (accessed September 14, 2006) The Appalachian Trail Conservancy claims the Appalachian Trail to be the longest hiking-only trail in the world. More than three million people hike segments of the trail each year. The trail was first proposed in 1921 and completed in 1937 after more than a decade of work. Improvements and changes have continued since then. It became the Appalachian National Scenic Trail under the National Trails System Act of 1968. The trail is maintained by 31 trail clubs and multiple partnerships, and managed by the National Park Service, United States Forest Service, and the nonprofit Appalachian Trail Conservancy. Most of the trail is in forest or wild lands, although some portions traverse towns, ...
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AT (form Factor)
In the era of IBM compatible personal computers, the AT form factor comprises the dimensions and layout ( form factor) of the motherboard for the IBM AT. Baby AT motherboards are a little smaller, measuring 8.5" by 13". Like the IBM PC and IBM XT models before it, many third-party manufacturers produced motherboards compatible with the IBM AT form factor, allowing end users to upgrade their computers for faster processors. The IBM AT became a widely copied design in the booming home computer market of the 1980s. IBM clones made at the time began using AT compatible designs, contributing to its popularity. In the 1990s many computers still used AT and its variants. Since 1997, the AT form factor has been largely supplanted by ATX. Design The original AT motherboard, later known as "Full AT", is , which means it will not fit in "mini desktop" or "minitower cases". The board's size also means that it takes up space behind the drive bays, making installation of new drives more dif ...
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Hayes Command Set
The Hayes command set (also known as the AT command set) is a specific command language originally developed by Dennis Hayes for the Hayes Smartmodem 300 baud modem in 1981. The command set consists of a series of short text strings which can be combined to produce commands for operations such as dialing, hanging up, and changing the parameters of the connection. The vast majority of dial-up modems use the Hayes command set in numerous variations. The command set covered only those operations supported by the earliest 300 bit/s modems. When new commands were required to control additional functionality in higher speed modems, a variety of one-off standards emerged from each of the major vendors. These continued to share the basic command structure and syntax, but added any number of new commands using some sort of prefix character – & for Hayes and USR, and \ for Microcom, for instance. Many of these were re-standardized on the Hayes extensions after the introduction of t ...
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Anti-tank Warfare
Anti-tank warfare originated from the need to develop technology and tactics to destroy tanks during World War I. Since the Triple Entente deployed the first tanks in 1916, the German Empire developed the first anti-tank weapons. The first developed anti-tank weapon was a scaled-up bolt-action rifle, the Mauser 1918 T-Gewehr, that fired a 13mm cartridge with a solid bullet that could penetrate the thin armor of tanks of the time and destroy the engine or ricochet inside, killing occupants. Because tanks represent an enemy's strong force projection on land, military strategists have incorporated anti-tank warfare into the doctrine of nearly every combat service since. The most predominant anti-tank weapons at the start of World War II in 1939 included the tank-mounted gun, anti-tank guns and anti-tank grenades used by the infantry, and ground-attack aircraft. Anti-tank warfare evolved rapidly during World War II, leading to the inclusion of infantry-portable weapons such as ...
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Athletic Training
Athletic training is an allied health care profession recognized by the American Medical Association (AMA)"What is an Athletic Trainer?". The Board of Certification Website. 2003. Athletic training is also recognized by the Health Resources Services Administration (HRSA) and the Department of Human and Health Services (HHS) as an allied health care profession. Athletic trainers (ATs) are health care professionals who render service or treatment under the direction of or in collaboration with a physician, in accordance with their education, training and the state's statutes, rules and regulations. The practice of athletic training encompasses health promotion and wellness and examination, diagnosis, immediate care, and rehabilitation of clients/patients with emergent, acute, and chronic health conditions. As defined by the Strategic Implementing Team of the National Athletic Trainers' Association (NATA) in August 2007. that "encompasses the prevention, examination, diagnosis, tre ...
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Acceptance Testing
In engineering and its various subdisciplines, acceptance testing is a test conducted to determine if the requirements of a specification or contract are met. It may involve chemical tests, physical tests, or performance tests. In systems engineering, it may involve black-box testing performed on a system (for example: a piece of software, lots of manufactured mechanical parts, or batches of chemical products) prior to its delivery. In software testing, the ISTQB defines ''acceptance testing'' as: Acceptance testing is also known as user acceptance testing (UAT), end-user testing, operational acceptance testing (OAT), acceptance test-driven development (ATDD) or field (acceptance) testing. Acceptance criteria are the criteria that a system or component must satisfy in order to be accepted by a user, customer, or other authorized entity. Overview Testing is a set of activities conducted to facilitate discovery and/or evaluation of properties of one or more items under test ...
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Appropriate Technology
Appropriate technology is a movement (and its manifestations) encompassing technological choice and application that is small-scale, affordable by locals, decentralized, labor-intensive, energy-efficient, environmentally sustainable, and locally autonomous. It was originally articulated as intermediate technology by the economist Ernst Friedrich "Fritz" Schumacher in his work ''Small Is Beautiful.'' Both Schumacher and many modern-day proponents of appropriate technology also emphasize the technology as people-centered. Appropriate technology has been used to address issues in a wide range of fields. Well-known examples of appropriate technology applications include: bike- and hand-powered water pumps (and other self-powered equipment), the universal nut sheller, self-contained solar lamps and streetlights, and passive solar building designs. Today appropriate technology is often developed using open source principles, which have led to ''open-source appropriate technology'' ( ...
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Antithrombin
Antithrombin (AT) is a small glycoprotein that inactivates several enzymes of the coagulation system. It is a 432-amino-acid protein produced by the liver. It contains three disulfide bonds and a total of four possible glycosylation sites. α-Antithrombin is the dominant form of antithrombin found in blood plasma and has an oligosaccharide occupying each of its four glycosylation sites. A single glycosylation site remains consistently un-occupied in the minor form of antithrombin, β-antithrombin. Its activity is increased manyfold by the anticoagulant drug heparin, which enhances the binding of antithrombin to factor IIa (prothrombin) and factor Xa. Nomenclature Antithrombin is also termed antithrombin III (AT III). The designations antithrombin I through to antithrombin IV originate in early studies carried out in the 1950s by Seegers, Johnson and Fell. Antithrombin I (AT I) refers to the absorption of thrombin onto fibrin after thrombin has activated fibrinogen. Antithro ...
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Austria
Austria, , bar, Östareich officially the Republic of Austria, is a country in the southern part of Central Europe, lying in the Eastern Alps. It is a federation of nine states, one of which is the capital, Vienna, the most populous city and state. A landlocked country, Austria is bordered by Germany to the northwest, the Czech Republic to the north, Slovakia to the northeast, Hungary to the east, Slovenia and Italy to the south, and Switzerland and Liechtenstein to the west. The country occupies an area of and has a population of 9 million. Austria emerged from the remnants of the Eastern and Hungarian March at the end of the first millennium. Originally a margraviate of Bavaria, it developed into a duchy of the Holy Roman Empire in 1156 and was later made an archduchy in 1453. In the 16th century, Vienna began serving as the empire's administrative capital and Austria thus became the heartland of the Habsburg monarchy. After the dissolution of the H ...
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Assistive Technology
Assistive technology (AT) is a term for assistive, adaptive, and rehabilitative devices for people with disabilities and the elderly. Disabled people often have difficulty performing activities of daily living (ADLs) independently, or even with assistance. ADLs are self-care activities that include toileting, mobility (ambulation), eating, bathing, dressing, grooming, and personal device care. Assistive technology can ameliorate the effects of disabilities that limit the ability to perform ADLs. Assistive technology promotes greater independence by enabling people to perform tasks they were formerly unable to accomplish, or had great difficulty accomplishing, by providing enhancements to, or changing methods of interacting with, the technology needed to accomplish such tasks. For example, wheelchairs provide independent mobility for those who cannot walk, while assistive eating devices can enable people who cannot feed themselves to do so. Due to assistive technology, disabled pe ...
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